Psychoactive drugs alter brain function and consciousness. There are four main groups of psychoactive drugs: stimulants, depressants, narcotics, and hallucinogens. Stimulants like cocaine, caffeine, nicotine, and amphetamines speed up brain and body functions but high doses can cause physical and mental effects like increased heart rate and anxiety. Caffeine is widely used but can be physically addictive causing withdrawal symptoms like headaches.