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DIFFERENCESB/WPSORIASIS&
SYSTEMICLUPUSERYTHEMATOSUS.
BY : DR. ROHAN SHRIVASTAVA
B.D.S ( DENTAL SURGEON)
Definition:
PSORIASIS :
 Psoriasis is an autoimmune disease that causes plaques,
which are itchy or sore patches of thick, dry, discolored
skin.
SYSTEMIC LUPUS ERYTHEMATOSUS :
 Systemic lupus erythematosus (SLE), is the most common type
of lupus. SLE is an autoimmune disease in which the immune
system attacks its own tissues, causing widespread inflammation
and tissue damage in the affected organs. It can affect the joints,
skin, brain, lungs, kidneys, and blood vessels.
Etiology:
PSORIASIS :
 the immune system mistakenly attacking healthy skin cells.
SYSTEMIC LUPUS ERYTHEMATOSUS :
 The cause of SLE is not clearly known. It may be linked to
the following factors:
• Genetic
• Environmental
• Hormonal
• Certain medicines
Symptoms:
PSORIASIS :
• Discolored patches or raised plaques of skin that are covered with scales
• Dry or cracked skin that bleeds
• Burning, itching, or soreness near the affected areas
• Pitted or thickened fingernails or toenails
• Swollen joints
SYSTEMIC LUPUS ERYTHEMATOSUS :
 Pain areas: in the muscles
 Pain types: can be sharp in the chest
 Pain circumstances: can occur while breathing
 Whole body: anaemia, fatigue, fever, or malaise
 Hair: hair loss or loss of scalp hair
 Skin: red rashes or scaly rashes
 Mouth: dryness or ulcers
 Also common: anxiety, blood in urine, clinical depression, face rash, flare, headache, joint
stiffness, raynaud's, sensitivity to light, swelling, water retention, or weight loss.
Diagnosis:
PSORIASIS :
 examine your skin, nails, and scalp for signs of this
condition.
SYSTEMIC LUPUS ERYTHEMATOSUS :
 Antinuclear antibody titer is the primary laboratory test
used to diagnose systemic lupus erythematosus.
Differential
Diagnosis:
PSORIASIS :
 Lichen planus, atopic dermatitis, nummular eczema,
pityriasis lichenoides chronica, and dermatomyositis.
SYSTEMIC LUPUS ERYTHEMATOSUS :
 Fever,Breathing problem (Dyspnoea),
Thromboembolism, Acute arthritis, Thrombocytopenia,
Cerebral lupus, Red cheeks, Malignancies , Eczema.
Treatment:
PSORIASIS :
 Treatment aims to remove scales and stop skin cells from
growing so quickly. Topical ointments, light therapy and
medication can offer relief.
SYSTEMIC LUPUS ERYTHEMATOSUS :
 there's no cure for lupus, current treatments focus on
improving quality of life through controlling symptoms and
minimizing flare-ups. This begins with lifestyle modifications,
including sun protection and diet. Further disease
management includes medication such as anti-
inflammatories and steroids.

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Psoriasis vs sle

  • 1. DIFFERENCESB/WPSORIASIS& SYSTEMICLUPUSERYTHEMATOSUS. BY : DR. ROHAN SHRIVASTAVA B.D.S ( DENTAL SURGEON)
  • 2. Definition: PSORIASIS :  Psoriasis is an autoimmune disease that causes plaques, which are itchy or sore patches of thick, dry, discolored skin. SYSTEMIC LUPUS ERYTHEMATOSUS :  Systemic lupus erythematosus (SLE), is the most common type of lupus. SLE is an autoimmune disease in which the immune system attacks its own tissues, causing widespread inflammation and tissue damage in the affected organs. It can affect the joints, skin, brain, lungs, kidneys, and blood vessels.
  • 3. Etiology: PSORIASIS :  the immune system mistakenly attacking healthy skin cells. SYSTEMIC LUPUS ERYTHEMATOSUS :  The cause of SLE is not clearly known. It may be linked to the following factors: • Genetic • Environmental • Hormonal • Certain medicines
  • 4. Symptoms: PSORIASIS : • Discolored patches or raised plaques of skin that are covered with scales • Dry or cracked skin that bleeds • Burning, itching, or soreness near the affected areas • Pitted or thickened fingernails or toenails • Swollen joints SYSTEMIC LUPUS ERYTHEMATOSUS :  Pain areas: in the muscles  Pain types: can be sharp in the chest  Pain circumstances: can occur while breathing  Whole body: anaemia, fatigue, fever, or malaise  Hair: hair loss or loss of scalp hair  Skin: red rashes or scaly rashes  Mouth: dryness or ulcers  Also common: anxiety, blood in urine, clinical depression, face rash, flare, headache, joint stiffness, raynaud's, sensitivity to light, swelling, water retention, or weight loss.
  • 5. Diagnosis: PSORIASIS :  examine your skin, nails, and scalp for signs of this condition. SYSTEMIC LUPUS ERYTHEMATOSUS :  Antinuclear antibody titer is the primary laboratory test used to diagnose systemic lupus erythematosus.
  • 6. Differential Diagnosis: PSORIASIS :  Lichen planus, atopic dermatitis, nummular eczema, pityriasis lichenoides chronica, and dermatomyositis. SYSTEMIC LUPUS ERYTHEMATOSUS :  Fever,Breathing problem (Dyspnoea), Thromboembolism, Acute arthritis, Thrombocytopenia, Cerebral lupus, Red cheeks, Malignancies , Eczema.
  • 7. Treatment: PSORIASIS :  Treatment aims to remove scales and stop skin cells from growing so quickly. Topical ointments, light therapy and medication can offer relief. SYSTEMIC LUPUS ERYTHEMATOSUS :  there's no cure for lupus, current treatments focus on improving quality of life through controlling symptoms and minimizing flare-ups. This begins with lifestyle modifications, including sun protection and diet. Further disease management includes medication such as anti- inflammatories and steroids.