Psoriasis and systemic lupus erythematosus (SLE) are both autoimmune diseases but they differ in their symptoms and causes. Psoriasis causes raised patches of thick, dry, scaly skin and is linked to the immune system mistakenly attacking healthy skin cells. SLE can affect multiple organs and cause a variety of symptoms like rashes, pain, fatigue, and hair loss. Its causes may be genetic, environmental, or linked to certain medicines. The two diseases are diagnosed differently, with doctors examining skin for psoriasis and using antibody tests for SLE. Treatments for psoriasis focus on removing scales and slowing skin cell growth, while SLE treatments control symptoms and minimize flare-