This document discusses properties of the weighted nearest rank method for finding percentiles. It proves two key properties:
1) If weights are integral, the nearest rank is the same whether calculated on the original or "exploded" sequence where each value appears the number of times as its weight.
2) For non-integral weights that sum to 1, the nearest rank can be approximated by calculating it on sequences where the weights are rounded up and corrected to sum to an integer N, and taking the limit as N approaches infinity. This relies on the assumption that the percentile q is not equal to any partial sum of weights.
On Application of Unbounded Hilbert Linear Operators in Quantum MechanicsBRNSS Publication Hub
This research work presents an important Banach space in functional analysis which is known and called
Hilbert space. We verified the crucial operations in this space and their applications in physics, particularly
in quantum mechanics. The operations are restricted to the unbounded linear operators densely defined
in Hilbert space which is the case of prime interest in physics, precisely in quantum machines. Precisely,
we discuss the role of unbounded linear operators in quantum mechanics, particularly, in the study of
Heisenberg uncertainty principle, time-independent Schrödinger equation, Harmonic oscillation, and
finally, the application of Hamilton operator. To make these analyses fruitful, the knowledge of Hilbert
spaces was first investigated followed by the spectral theory of unbounded operators, which are claimed
to be densely defined in Hilbert space. Consequently, the theory of probability is also employed to study
some systems since the operators used in studying these systems are only dense in H (i.e., they must (or
probably) be in the domain of H defined by L2 ( ) −∞,+∞ ).
Application of Schrodinger Equation to particle in one Dimensional Box: Energ...limbraj Ravangave
It is very interesting application of Schrodinger equation.. we find the solution to Schrodinger equation for particle moving under some type of interaction. the motion of particle in one dimensional box is to and fro motion in uniform potential. the problem is explore in easy way and better for understanding to the students.
visit our blog
https://elearnerphysics.blogspot.com/
What is a continuous structure?
How to analyse the vibration of string, bars and shafts?
How to analyse the vibration of beams?
#WikiCourses
https://wikicourses.wikispaces.com/Topic+Vibration+of+Continuous+Structures
https://eau-esa.wikispaces.com/Vibration+of+structures
On Application of Unbounded Hilbert Linear Operators in Quantum MechanicsBRNSS Publication Hub
This research work presents an important Banach space in functional analysis which is known and called
Hilbert space. We verified the crucial operations in this space and their applications in physics, particularly
in quantum mechanics. The operations are restricted to the unbounded linear operators densely defined
in Hilbert space which is the case of prime interest in physics, precisely in quantum machines. Precisely,
we discuss the role of unbounded linear operators in quantum mechanics, particularly, in the study of
Heisenberg uncertainty principle, time-independent Schrödinger equation, Harmonic oscillation, and
finally, the application of Hamilton operator. To make these analyses fruitful, the knowledge of Hilbert
spaces was first investigated followed by the spectral theory of unbounded operators, which are claimed
to be densely defined in Hilbert space. Consequently, the theory of probability is also employed to study
some systems since the operators used in studying these systems are only dense in H (i.e., they must (or
probably) be in the domain of H defined by L2 ( ) −∞,+∞ ).
Application of Schrodinger Equation to particle in one Dimensional Box: Energ...limbraj Ravangave
It is very interesting application of Schrodinger equation.. we find the solution to Schrodinger equation for particle moving under some type of interaction. the motion of particle in one dimensional box is to and fro motion in uniform potential. the problem is explore in easy way and better for understanding to the students.
visit our blog
https://elearnerphysics.blogspot.com/
What is a continuous structure?
How to analyse the vibration of string, bars and shafts?
How to analyse the vibration of beams?
#WikiCourses
https://wikicourses.wikispaces.com/Topic+Vibration+of+Continuous+Structures
https://eau-esa.wikispaces.com/Vibration+of+structures
To give the complete list of Uq(sl2)-actions of the quantum plane, we first obtain the structure of quantum plane automorphisms. Then we introduce some special symbolic matrices to classify the series of actions using the weights. There are uncountably many isomorphism classes of the symmetries. We give the classical limit of the above actions.
This lecture notes were written as part of the course "Pattern Recognition and Machine Learning" taught by Prof. Dinesh Garg at IIT Gandhinagar. This lecture notes deals with Linear Regression.
This pdf is about the Schizophrenia.
For more details visit on YouTube; @SELF-EXPLANATORY;
https://www.youtube.com/channel/UCAiarMZDNhe1A3Rnpr_WkzA/videos
Thanks...!
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
1. Proofs of some elementary facts on the weighted
nearest rank
Vasilis. Anagnostopoulos
April 20, 2021
Abstract
In this note we prove two remarkable properties of the nearest rank
when weights are employed. We use elementary properties to provide
proofs and show that nearest rank is competitive to other percentile
methods in simplicity. The properties also prove its consistency both
when the weights are integral or not. It supports the material presented
in a article about weighted medians in medium.
As explained in The nearest rank method, nearest rank is a good com-
promise in finding the percentile and asymptotically they are the same. The
definition also extends naturally for the weighted case we are interested in.
To this end, lets craft a ”math friendly definition” that will be convenient
enough to help us prove theorems. Suppose we are given a series of weighted
values, say {(x1, w1), . . . , (xm, wm)}. Since this series could model prices
(x) and quantities (w) it is natural to assume that the weights are positive.
Also we make the assumption that the series is sorted in increasing prices
so that cumulative distribution function can be defined. To summarize, the
constraints on this series take the form:
wi ≥ 0 ∀i (1)
wi ≥ wi−1 ∀i ≥ 1 (2)
Now we are ready to give the definitions.
Definition 0.1 (Nearest Rank). We define the weighted q-nearest rank
index as
mq = min{i :
Pi
j=1 wj
Pm
j=1 wj
≥ q} (3)
and the weighted q-nearest rank is
xmq . (4)
1
2. Remark. It is an easy task to prove that the definition given here and the
one in Wikipedia are equivalent. Just match the definitions for the case
where wi = 1 ∀i.
We will find out that these definitions, even though they deviate some-
how from the common median (q-percentile), they satisfy some very desir-
able properties.
1 The invariant property of nearest rank for inte-
gral weights
In this section we prove the first interesting property of nearest rank. If the
weights are integral and we ”explode” the sequence then, the nearest rank
calculated by definition 0.1 is the same whether we apply it on the original
or the exploded sequence. Consider as above a sequence of integral weighted
samples satisfying (1) and (2). Its exploded version is just the same sequence
with every value appearing as many times as its weight. In other words we
replace this sequence
{(x1, w1), (x2, w2), . . . , (xm, wm)} (5)
with
{(x1, 1), . . . , (x1, 1)
| {z }
w1
, (x2, 1), . . . , (x2, 1)
| {z }
w2
, . . . , (xm, 1), . . . , (xm, 1)
| {z }
wm
} (6)
or equivalently
{x1, . . . , x1
| {z }
w1
, x2, . . . , x2
| {z }
w2
, . . . , xm, . . . , xm
| {z }
wm
} (7)
The ”conditions” (1) and (2) are satisfied for the exploded sequence too.
Theorem 1.1. Exploded and unexploded sequences have the same nearest
rank.
Proof. Smart counting is at the core of this theorem. Suppose the calculation
on the ”exploded sequence gives an index nq. Suppose that the x value at
this position, has index m0
q in the 1, . . . , m interval. What we are trying to
prove is that
m0
q = mq. (8)
Please, take your time to understand why. Now, by definition for the
exploded sequence
2
3. Pnq
j=1 1
Pm
j=1 wj
≥ q (9)
and consequently
Pm0
q
j=1 wj
Pm
j=1 wj
≥ q ⇒ m0
q ≥ mq (10)
by the minimality of mq. On the other hand, again by definition of the
exploded sequence, the condition
Pmq
j=1 wj
Pm
j=1 wj
≥ q (11)
implies
nq
X
j=1
1 ≤
mq
X
j=1
wj. (12)
As a matter of fact we have the margin to increase nq until we change
x. This means
m0
q ≤ mq (13)
and the theorem is proved.
2 Nearest rank is accessible through samples
While the previous theorem was more or less expected the next property is
unexpected and makes it super useful for non-integral weights. Suppose we
would like to find the nearest rank of the following sequence satisfying (1)
and (2)
{(x1, w1), (x2, w2), . . . , (xm, wm)} (14)
with nearest rank xmq . We add just another constraint now. the weights
are positive probabilities. The weights now, sum to 1
m
X
i=1
wi = 1 (15)
Suppose now we create another sequence
{(x1, w0
1), (x2, w0
2), . . . , (xm, w0
m)} (16)
3
4. with weights
w0
i = [Nwi]. (17)
In the equation above the reader can identify [.] as the integer part. The
hope is that in the limit of infinite N the previous theorem applies.
By the properties of the integer part
[x] ≤ x < [x] + 1 (18)
and consequently (as the original weights sum to 1)
N − m <
m
X
i=1
[Nwi] ≤ N.
The new weights now do not sum to N, possibly something less but the
error is bounded by m. In order to correct this shortcoming we add 1’s
to the first w0
i until we get to N. This amounts to selecting a decreasing
sequence of 0/1 numbers, say ki such that
w00
i = [Nwi] + ki. (19)
sums to N. Let the nearest rank of this sequence with weights w00 be
xm(N,q) .
We also need a very technical assumption that will help convergence.
Definition 2.1 (Admissible q). We say that q is admissible for the weights
when
q 6=
k
X
i=1
wi for all k. (20)
We can state our theorem.
Theorem 2.1. Non integral nearest rank is accessible through integral com-
putations when weights are probabilities and the q is admissible for them.
In other words
lim
N→∞
xm(N,q)
N
= xmq (21)
Proof. Smart counting is crucial here too. We also make use of 18.
By definition
4
5. mq
X
i=1
wi ≥ q ⇒ (22)
mq
X
i=1
(1 + [Nwi]) ≥ Nq ⇒ (23)
m +
mq
X
i=1
(ki + [Nwi]) ≥ Nq ⇒ (24)
Pmq
i=1 w00
i
Pm
i=1 w00
i
≥ q −
m
N
. (25)
In a similar way,
Pm(N,q)
i=1 w00
i
Pm
i=1 w00
i
≥ q ⇒ (26)
m(N,q)
X
i=1
(ki + [Nwi]) ≥ Nq ⇒ (27)
m +
m(N,q)
X
i=1
Nwi ≥ Nq ⇒ (28)
m(N,q)
X
i=1
wi ≥ q −
m
N
. (29)
We cannot have an infinite N such that m(N, q) < mq. This can be see
from 27 because then
mq−1
X
i=1
wi ≥
m(N,q)
X
i=1
wi ≥ q −
m
N
. (30)
By taking the limits
mq−1
X
i=1
wi ≥ q (31)
which contradicts the minimality of mq. Consequently from a N0 on-
wards
m(N, q) ≥ mq. (32)
Also we can see from 23 that
5
6. m(N, q) > mq + 1. (33)
cannot happen for infinite N . So, from a N0 onwards
either m(N, q) = mq or m(N, q) = mq + 1. (34)
This is where admissibility comes into play. Suppose that m(N, q) =
mq + 1, again for infinite N. By the minimality of m(N, q) and 23 we have
q −
m
N
≤
Pmq)
i=1 w00
i
Pm
i=1 w00
i
< q. (35)
By taking the limits
Pmq)
i=1 w00
i
Pm
i=1 w00
i
= q (36)
which contradicts the admissibility.
The technical assumption come into play in order to select one of the
two possible cases. Otherwise the integral median would oscillate. Take for
example the value 3 and 4 with weights 1
2 respectively. It is not difficult to
see that
m(N,
1
2
) =
3 for N = even
4 for N = odd
are the two possible cases. No convergence can happen.
6