There are two main types of cells: prokaryotic and eukaryotic. Prokaryotic cells were the earliest life on Earth and lack membrane-bound organelles, while eukaryotic cells evolved later and have organelles within membranes. Key differences include prokaryotes being smaller, unicellular, and lacking a nucleus, while eukaryotes can be multicellular, have organelles like mitochondria and chloroplasts, and contain DNA within the nucleus. Both share some basic structures like the cell membrane but eukaryotes are generally larger and more complex.