Contraception where have we been and where are we going is a presentation made by Dr.Laxmi Shrikhande who is a Fertility Specialist, Laparoscopic Surgeon & no scar Hysterectomy Specialist and a leading Gynaecologist from Nagpur
Speaking at the 2015 CCIH Annual Conference, Dr. Douglas Huber discusses injectable contraceptives and addresses common misunderstandings and misperceptions about how they work and side effects.
Evolution and current practices in emergency contraceptives BY DR ALKA MUKHER...alka mukherjee
ey facts
Emergency contraception (EC) can prevent up to over 95% of pregnancies when taken within 5 days after intercourse.
EC can be used in the following situations: unprotected intercourse, concerns about possible contraceptive failure, incorrect use of contraceptives, and sexual assault if without contraception coverage.
Methods of emergency contraception are the copper-bearing intrauterine devices (IUDs) and the emergency contraceptive pills (ECPs).
A copper-bearing IUD is the most effective form of emergency contraception available.
The emergency contraceptive pill regimens recommended by WHO are ulipristal acetate, levonorgestrel, or combined oral contraceptives (COCs) consisting of ethinyl estradiol plus levonorgestrel.
Contraception where have we been and where are we going is a presentation made by Dr.Laxmi Shrikhande who is a Fertility Specialist, Laparoscopic Surgeon & no scar Hysterectomy Specialist and a leading Gynaecologist from Nagpur
Speaking at the 2015 CCIH Annual Conference, Dr. Douglas Huber discusses injectable contraceptives and addresses common misunderstandings and misperceptions about how they work and side effects.
Evolution and current practices in emergency contraceptives BY DR ALKA MUKHER...alka mukherjee
ey facts
Emergency contraception (EC) can prevent up to over 95% of pregnancies when taken within 5 days after intercourse.
EC can be used in the following situations: unprotected intercourse, concerns about possible contraceptive failure, incorrect use of contraceptives, and sexual assault if without contraception coverage.
Methods of emergency contraception are the copper-bearing intrauterine devices (IUDs) and the emergency contraceptive pills (ECPs).
A copper-bearing IUD is the most effective form of emergency contraception available.
The emergency contraceptive pill regimens recommended by WHO are ulipristal acetate, levonorgestrel, or combined oral contraceptives (COCs) consisting of ethinyl estradiol plus levonorgestrel.
Dr. Douglas Huber discusses a Christian approach to family planning, including technology, programs, and advocacy. He explores attitudes on family planning among various Christian denominations and methods used. He also explains how various methods work to prevent unintended pregnancies.
IUI is a basic but effective form of fertiltiy treatment and can be a viable alternative to the expensive IVF / test tube baby treatment that is normally advised.
This presentation will be very useful for the practising gynecologists, IVF specialists and General practitioners who perform IUI.
Even patients on going through this presentation will be more educated about iui.
Please reach out to me on 9833032120 by whatsapp / Telegram or phone call or email on dalalsj@gmail.com for further details / treatment options.
High cost involved in establishing and maintaining a good ART laboratory, the constant need to upgrade and adopt new technology and the use of stimulation protocols that use expensive drugs, makes ART treatment expensive.
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IUI is a basic but effective form of fertiltiy treatment and can be a viable alternative to the expensive IVF / test tube baby treatment that is normally advised.
This presentation will be very useful for the practising gynecologists, IVF specialists and General practitioners who perform IUI.
Even patients on going through this presentation will be more educated about iui.
Please reach out to me on 9833032120 by whatsapp / Telegram or phone call or email on dalalsj@gmail.com for further details / treatment options.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
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is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
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(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
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Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
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Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
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Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
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Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
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Primitive, less old, and new olfactory systems with different path
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Preview Contraception where have we been and where are we going
1. • Chairperson Elect ICOG –Indian College of OB/GY
• National Corresponding Editor-Journal of OB/GY of India JOGI
• National Corresponding Secretary Association of Medical Women, India
• Founder Patron & President –ISOPARB Vidarbha Chapter
• Chairperson-IMS Education Committee 2021-23
• President-Association of Medical Women, Nagpur AMWN 2021-24
• Nagpur Ratan Award @ hands of Union Minister Shri Nitinji Gadkari
• Received Bharat excellence Award for women’s health
• Received Mehroo Dara Hansotia Best Committee Award for her work as
Chairperson HIV/AIDS Committee, FOGSI 2007-2009
• Received appreciation letter from Maharashtra Government for her work in the
field of SAVE THE GIRL CHILD
• Senior Vice President FOGSI 2012
• President Menopause Society, Nagpur 2016-18
• President Nagpur OB/GY Society 2005-06
• Delivered 11 orations and 450 guest lectures
• Publications-Thirty National & Eleven International
• Sensitized 2 lakh boys and girls on adolescent health issues
Dr. Laxmi Shrikhande
MBBS; MD(OB/GY);
FICOG; FICMU; FICMCH
Medical Director-
Shrikhande Fertility Clinic
Nagpur, Maharashtra
2. Contraception- Where have
we been and
where are we going?
Dr Laxmi Shrikhande
Consultant –Shrikhande Hospital & Research Centre
Pvt Ltd
Nagpur
3. Population Projection – India & Global
India accounts for 17% of world’s population
By 2050 : expected population :
India : 1.63 Billion
World’s population 9.3 billion
(16% in 2050 will be over 65 – more would be over 85 yrs)
• Population increase due to
lack of contraception
Decline in infant mortality
Increase in life expectancy.
4. SDGs and the World Population
• The goals are laudable but cannot be achieved with an ever increasing
population.
• To survive and thrive; the denominator i.e. the population need to be stable.
Contraception is the need of the hour
Global : Unmet need
225 million women in the reproductive age group who want contraception.
80 million unwanted pregnancies
5. 15.6 Million Abortions Occur
Annually in India
The Lancet Global Health—was conducted jointly by researchers at the International Institute for Population Sciences (IIPS), Mumbai; the
Population Council, New Delhi; and the New York–based Guttmacher Institute. 2017
6. Current use of family planning methods (among
married women of reproductive age)
India (%)
Total unmet need 9.4
Any modern method use 56.5
Female sterilization 37.9
Male sterilisation 0.3
IUD/PPIUCD 2.1
Pill 5.1
Condom 9.5
Injectables 0.6
Source: National Family Health Survey (NFHS-5) 2019-20. Ministry of Health & Family Welfare, Government of India
• Unmet need : 9.4 %, indicating that 1 in 10 women want to space or limit births, are not able to do so
• Undue burden of family planning on women, the focus continues to be on female sterilization.
• Adoption of spacing methods and male participation remain low.
11. Injectable Contraceptive MPA (Antara Program)
Long-acting reversible contraceptive (LARC)
• 4th most prevalent contraceptive
• Currently 42 million women worldwide use MPA as a method of choice
• Developed in 1954 by the Upjohn Company for treatment of
endometriosis and habitual or threatened abortions
• Since 1960, licensed to be used as Contraceptive
• USFDA in Feb 1992 approved DMPA as a contraceptive
• Currently approved for use in more than 130 countries
(WHO: Family Planning: A Global Handbook for Providers)
12. Two New Progestin-only contraceptives introduced in India
DMPA –SC (Sayana Press)
Subcutaneous injectables
Subdermal Progesterone Implants
14. DMPA-SC Self injection Way forward …
Client self-
injection under
supervision at
PHC (two visits)
Self-injection
independently at home
for two doses
Client returns to healthcare
facility after six months for
check up and DMPA-SC re-
supply
DMPA-SC can be self –Administered- Improve autonomy
Cost effectiveness : travel, service provision
Improved continuation rates
DMPA SC
injection
admistered by
Healthcare
provider
16. Implants - LARC
Implanon NXT (Nexplanon): 1-rod
effective for 3 years
68 mg of Etonorgestrel
bio-equivalent to Implanon but has an
addition of barium sulphate that makes it
radio-opaque.
Jadelle: 2-rod
effective for 5 years
Levonogestrel 75 mg
Progestin-filled small flexible rod
Inserted under the skin of the Inner upper arm
17. Emergency contraception
Ulipristal acetate
( progesterone receptor modulator)
Single dose 30mg within 120 hours
The UPA EC regimen is slightly more
effective than LNG as shown by a
meta-analysis (n = 3242) of two
randomised controlled comparative
trials
UPA may be more effective than
LNG for women who are obese.
Cu-IUD
Inserted within 120 hours
Large systematic review of 42 studies
showed that Cu‐IUD is the most
effective EC with failure rates of
<0.1%.
Levonorgestrel 1.5 mg single dose ?
Although for use within 72 hours, there is evidence that efficacy may be maintained up to 96 hours post UPSI
Piaggio G, Kapp N, von Hertzen H. Effect on pregnancy rates of the delay in the administration of levonorgestrel for emergency contraception: a combined
analysis of four WHO trials. Contraception 2011;84:35–9
Cheng L, Che Y, Gulmezoglu AM. Interventions for emergency contraception. Cochrane Database Syst Rev 2012;8:CD001324
18. Other newer routes of administration of combined
hormonal contraception
Vaginal rings Contraceptive Patch
Monthly combined
Injectable
19. Women are Dying Every Day…
• Every 15 minute……., somewhere in India, a woman dies in
pregnancy or childbirth
-One – Third of these deaths could be avoided if women
who wanted effective contraception had access to it
21. My World of sharing happiness!
Shrikhande Fertility Clinic
Ph- 91 8805577600
shrikhandedrlaxmi@gmail.com
22. The more you give, the more you will get.
Then life will become a sheer dance of love.
H. H. Sri. Sri. Ravishankar
The Art of Living
Thank you
Editor's Notes
Ask participants:
What are contraceptive implants? <allow participants to answer>
What are some qualities of implants that are unique to this method? <allow participants to answer>
How are implants different from other hormonal methods? <allow participants to answer>
Which brands of implants are available in the facility where you work (or in their country, pharmacy, or program)? <allow participants to answer>
After participants respond, click the mouse to reveal the information on the slide> and discuss the brands and types of Implants. See session plan for more details.
Illustration credits: WHO; Salim Khalaf/FHI