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Gen Z spends the most amount of time on social media, so the notion that social media negatively affects mental health appears to be correlated. Unfortunately, Gen Z is also the generation that’s least comfortable discussing mental health concerns with healthcare professionals. Only 40% of them state they’re comfortable discussing their issues with a professional compared to 60% of Millennials and 65% of Boomers.
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The treatment consists of replacing lost liquids and electrolytes (drinking drinking water and other recommended liquids, including consumption of juicy fruits such as papayas, apples, pears, among others that contain water in their composition).
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Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.
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Staging involves determining the size of the tumor (T), the involvement of regional lymph nodes (N), and the presence of distant metastasis (M). The American Joint Committee on Cancer (AJCC) staging system is commonly used. Accurate staging is critical as it guides treatment decisions.
Treatment Options
Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.
Call Girls In Mumbai +91-7426014248 High Profile Call Girl Mumbai
Call Girls In Mumbai +91-7426014248 High Profile Call Girl Mumbai
Hemodialysis: Chapter 6, Hemodialysis Adequacy and Dose - Dr.Gawad
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- Video recording of this lecture in Arabic language: https://youtu.be/ECILGWtgZko
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
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Pharmacology of 5-hydroxytryptamine and Antagonist
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It is mostly found in the brain, intestines, and blood platelets.
5-HT is utilised to transport messages between nerve cells, is known to be involved in smooth muscle contraction, and adds to overall well-being and pleasure, among other benefits. 5-HT regulates the body's sleep-wake cycles and internal clock by acting as a precursor to melatonin.
It is hypothesised to regulate hunger, emotions, motor, cognitive, and autonomic processes.
Pharmacology of Prostaglandins, Thromboxanes and Leukotrienes
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How to Prepare For a Successful Job Search for 2024
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Social Media Marketing Trends 2024 // The Global Indie Insights
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Trends In Paid Search: Navigating The Digital Landscape In 2024
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Watch Sreekant Lanka from iQuanti and Irina Klein from OneMain Financial as they dive into the future of paid search and explore the trends, strategies, and technologies that will shape the search marketing landscape.
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5 Public speaking tips from TED - Visualized summary
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With over one billion views in a year, it’s no wonder that so many speakers are looking to TED for ideas on how to share their message more effectively.
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See the full article and more summaries like this on SpeakerHub here: https://speakerhub.com/blog/5-presentation-tips-ted-gives-its-speakers
See the original article on Forbes here:
http://www.forbes.com/forbes/welcome/?toURL=http://www.forbes.com/sites/carminegallo/2016/05/06/5-public-speaking-tips-ted-gives-its-speakers/&refURL=&referrer=#5c07a8221d9b
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* ChatGPT and OpenAI belong to OpenAI, L.L.C.
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More than Just Lines on a Map: Best Practices for U.S Bike RoutesProject for Public Spaces & National Center for Biking and Walking
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Presenters:
Presenter: Kevin Luecke Toole Design Group
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• Go beyond discussing the status of everyday work to higher level topics, including recognition, performance, development, and career aspirations
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About the Speakers
Jamie Resker - Founder and Practice Leader for Employee Performance Solutions (EPS)
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Teala Wilson - Senior Consultant, Strategic Services, Saba Software
Teala is a Talent Management Consultant at Halogen Software, now a part of Saba Software. She has worked with teams on a national and global level supporting human resources in areas such as performance management, recruitment, employee benefit programs, training and talent development, workforce planning and internal communications. Teala also has a personal passion for visual arts and design.
Want to learn more? Join us for an upcoming Product Tour!
http://bit.ly/2yitfqu
Introduction to C Programming Language
This video by Simplilearn will explain to you Introduction to C Programming Language. Introduction to C Programming Language Tutorial For Beginners will explain to you the C language's history, C's importance, its features, real-world applications, and some of its advantages and disadvantages.
00:00 Introduction to C
1:42-History of C language
Dennis Ritchie, a computer scientist, could identify the gaps and tap out the best features from both B and BCPL languages to invent a new hybrid.
Hence, C was born in 1972 at Bell Laboratories. A remarkably simple and highly readable programming language resulted in groundbreaking advancements in the IT industry.
2:48-Importance and unraveling the powerful capabilities of C,
The widespread use of C started to take over the IT industry. Unraveling the potential of C, the designers began to discover new possibilities that led them to focus on the big picture.
3:56-C's cutting-edge features
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6:35-The popular real-world applications of C
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-google file system
-Mozilla
-Graphical user interface
8:30-The advantages and disadvantages of C
10:34-The popular IT companies and their domains that employ C
· MasterCard
· IBM
· Flipkart
· Dell
· Twitter
· GitHub and twitch
11:09-First c program.
🔥 Explore our FREE courses with completion certificates: https://www.simplilearn.com/skillup-f...
✅Subscribe to our Channel to learn more about the top Technologies: https://bit.ly/2VT4WtH
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#IntroductiontoCProgrammingLanguage #CLanguage #CProgramming #CProgram #CProgrammingLanguage #LearnCProgramming #HowToCodeInCForBeginners #CTutorialForBeginners #LearnCProgramming #Simplilearn
Dennis Ritchie, a computer scientist, was able to identify the gaps and tap out the best features from both B and BCPL languages to invent a new hybrid.
Hence, C was born in 1972 at Bell Laboratories. A remarkably simple and highly readable programming language resulted in groundbreaking advancements in the IT industry.
✅What is C++ Programming?
C++ is an enhanced and extended version of C programming language, developed by Bjarne Stroustrup in 1979 as part of his Ph.D. project. Bjarne developed what he called ‘C with Classes’ (later renamed C++) because he felt limited by the existing programming languages that were not ideal for large scale projects. He used C to build what he wanted because C was already a general-purpose language that was efficient and fast in its operations.
✅C++ Career Prospects:
With just C++ programming expertise, you will have excellent job opportunities, salaries, and career prospects. However, for a career based on programming languages such as Java and Python (which are in more demand than C++) or for careers based on front-end, back-end, and full-stack
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FaceLake ® FL400 Pulse Oximeter
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