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TB and HIV infection in the WHO European Region
Dr Zsuzsanna Jakab, Regional Director, WHO Regional Office for Europe
Tbilisi, Georgia, 30 September 2015
Regional high-level dialogue on successful transition to domestic funding of the response to HIV
infection and TB in eastern European and central Asian (EECA) countries: “Road to success”
2
Fastest decrease in TB prevalence of all WHO regions
313
280
31 29
122 121
50
39
198
183
96 87
20
200
2009 2010 2011 2012 2013
per100000population(log)
6%
__
1.9%
2.4%
0.3%
2.0%
2.8% African
South-East Asia
Eastern Mediterranean
Western Pacific
European
The Americas
3
TB and MDR-TB burden, 2013
41%
25%
21%
9%
4% 3%
30%
15%
24%
6%
25%
2%
0%
5%
10%
15%
20%
25%
30%
35%
40%
45%
S.E. Asia Africa W. Pacific E. Mediterranean Europe Americas
TB MDR-TB
4
TB/HIV co-infection
2.8
7.8
0
1
2
3
4
5
6
7
8
9
2006 2007 2008 2009 2010 2011 2012 2013
%HIVinfectionamongTBcases
5
Core achievements
Baseline 2015
Estimated prevalence of MDR-TB 9.1 per 100 000 8.4 per 100 000
MDR-TB detection rate 30% 50%
MDR-TB treatment coverage 63% 100%
Approach Small-scale pilot
projects
Nationwide integrated
programmes
6
Stabilization of MDR-TB among previously treated
cases
38.3%
48.6% 48.0%
0%
10%
20%
30%
40%
50%
60%
2007 2008 2009 2010 2011 2012 2013
MDR among previously treated cases
7
Key results
• 1 million TB patients cured, including 53 000 with MDR–TB
• 200 000 MDR–TB cases averted
• 2.6 million lives saved
• US$ 11 billion saved
8
Regional response: “From Berlin, 2007,
to Vilnius, 2015”
9
What is new in the new TB action plan?
• Scale-up of rapid diagnosis
• Expanded patient-centred care models
• Shorter, more effective treatment regimens and new
medicines
• Research for new tools
• Intersectoral approach to inequities
10
TB action plan for the WHO European Region
2016–2020
• 3.1 million lives will have been saved
• 1.4 million TB patients will have been cured
• 1.7 million new cases of all forms of TB
will have been prevented
• US$ 48 billion will have been saved
11
Less progress in prevention and control of HIV infection in
the WHO European Region
Despite progress in implementation
of the European action plan for
HIV/AIDS 2012–2015 and more
people on treatment, the HIV
epidemic in this Region is still
increasing.
12
0
20
40
60
80
100
120
140
160
2004 2005 2006 2007 2008 2009 2010 2011 2012 2013
Thousands
WHO European Region
East
West
Centre
WHO European Region
Centre
West
East
Newly diagnosed HIV infections, WHO European Region,
2004–2013
13
Distribution of newly diagnosed HIV infections in 2013
14
Populations disproportionately affected
• People who inject drugs (and their sexual
partners)
• Men who have sex with men
• Sex workers
• Transgender people
• Prisoners
• Migrants
15
Late diagnoses in Europe
WHO European Region:
Percentages of new cases of HIV
infection with CD4 cell counts
< 350/mm3 and < 200/mm3 at
diagnosis, 2013
Source: ECDC/WHO (2014). HIV/AIDS Surveillance in Europe, 2013
49%
27%
16
East:
Percentages of new cases of HIV infection
with CD4 cell count < 350/mm3 at
diagnosis, by transmission mode, 2013
Late diagnoses in eastern Europe
17
Treatment gap
People with HIV infection receiving antiretroviral therapy (ART) in Europe, 2009–2013
0
200
400
600
800
1000
1200
1400
1600
1800
2000
2009 2010 2011 2012 2013
Thousands
ART western and central Europe
ART eastern Europe
Cumulative HIV cases
26%↑
124%↑
41%↑
18
Prevention of mother-to-child transmission
14%
37%
67%
75%
81%
92%
75%
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%
Eastern Mediterranean Region
South-East Asia Region
Western Pacific Region
African Region
Region of the Americas
European Region
Global
Percentage of pregnant women living with HIV
infection in low- and middle-income countries who
received ART, globally and by WHO region, 2014
19
Global health sector strategies on HIV infection, viral
hepatitis and STIs, 2016–2021
http://www.who.int/hiv/strategy2016-2021/en/
Strategic directions:
• Information for focus and accountability
• Interventions for impact
• Delivery for quality and equity
• Financing for sustainability
• Innovation for acceleration Regional
consultation
(33 countries),
June 2015
20
Thank you very much for your attention

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Presentation - TB and HIV infection in the WHO European Region

  • 1. © Carl Cordonnier © Maxim Dondiuk© Andrei Dadu TB and HIV infection in the WHO European Region Dr Zsuzsanna Jakab, Regional Director, WHO Regional Office for Europe Tbilisi, Georgia, 30 September 2015 Regional high-level dialogue on successful transition to domestic funding of the response to HIV infection and TB in eastern European and central Asian (EECA) countries: “Road to success”
  • 2. 2 Fastest decrease in TB prevalence of all WHO regions 313 280 31 29 122 121 50 39 198 183 96 87 20 200 2009 2010 2011 2012 2013 per100000population(log) 6% __ 1.9% 2.4% 0.3% 2.0% 2.8% African South-East Asia Eastern Mediterranean Western Pacific European The Americas
  • 3. 3 TB and MDR-TB burden, 2013 41% 25% 21% 9% 4% 3% 30% 15% 24% 6% 25% 2% 0% 5% 10% 15% 20% 25% 30% 35% 40% 45% S.E. Asia Africa W. Pacific E. Mediterranean Europe Americas TB MDR-TB
  • 4. 4 TB/HIV co-infection 2.8 7.8 0 1 2 3 4 5 6 7 8 9 2006 2007 2008 2009 2010 2011 2012 2013 %HIVinfectionamongTBcases
  • 5. 5 Core achievements Baseline 2015 Estimated prevalence of MDR-TB 9.1 per 100 000 8.4 per 100 000 MDR-TB detection rate 30% 50% MDR-TB treatment coverage 63% 100% Approach Small-scale pilot projects Nationwide integrated programmes
  • 6. 6 Stabilization of MDR-TB among previously treated cases 38.3% 48.6% 48.0% 0% 10% 20% 30% 40% 50% 60% 2007 2008 2009 2010 2011 2012 2013 MDR among previously treated cases
  • 7. 7 Key results • 1 million TB patients cured, including 53 000 with MDR–TB • 200 000 MDR–TB cases averted • 2.6 million lives saved • US$ 11 billion saved
  • 8. 8 Regional response: “From Berlin, 2007, to Vilnius, 2015”
  • 9. 9 What is new in the new TB action plan? • Scale-up of rapid diagnosis • Expanded patient-centred care models • Shorter, more effective treatment regimens and new medicines • Research for new tools • Intersectoral approach to inequities
  • 10. 10 TB action plan for the WHO European Region 2016–2020 • 3.1 million lives will have been saved • 1.4 million TB patients will have been cured • 1.7 million new cases of all forms of TB will have been prevented • US$ 48 billion will have been saved
  • 11. 11 Less progress in prevention and control of HIV infection in the WHO European Region Despite progress in implementation of the European action plan for HIV/AIDS 2012–2015 and more people on treatment, the HIV epidemic in this Region is still increasing.
  • 12. 12 0 20 40 60 80 100 120 140 160 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 Thousands WHO European Region East West Centre WHO European Region Centre West East Newly diagnosed HIV infections, WHO European Region, 2004–2013
  • 13. 13 Distribution of newly diagnosed HIV infections in 2013
  • 14. 14 Populations disproportionately affected • People who inject drugs (and their sexual partners) • Men who have sex with men • Sex workers • Transgender people • Prisoners • Migrants
  • 15. 15 Late diagnoses in Europe WHO European Region: Percentages of new cases of HIV infection with CD4 cell counts < 350/mm3 and < 200/mm3 at diagnosis, 2013 Source: ECDC/WHO (2014). HIV/AIDS Surveillance in Europe, 2013 49% 27%
  • 16. 16 East: Percentages of new cases of HIV infection with CD4 cell count < 350/mm3 at diagnosis, by transmission mode, 2013 Late diagnoses in eastern Europe
  • 17. 17 Treatment gap People with HIV infection receiving antiretroviral therapy (ART) in Europe, 2009–2013 0 200 400 600 800 1000 1200 1400 1600 1800 2000 2009 2010 2011 2012 2013 Thousands ART western and central Europe ART eastern Europe Cumulative HIV cases 26%↑ 124%↑ 41%↑
  • 18. 18 Prevention of mother-to-child transmission 14% 37% 67% 75% 81% 92% 75% 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% Eastern Mediterranean Region South-East Asia Region Western Pacific Region African Region Region of the Americas European Region Global Percentage of pregnant women living with HIV infection in low- and middle-income countries who received ART, globally and by WHO region, 2014
  • 19. 19 Global health sector strategies on HIV infection, viral hepatitis and STIs, 2016–2021 http://www.who.int/hiv/strategy2016-2021/en/ Strategic directions: • Information for focus and accountability • Interventions for impact • Delivery for quality and equity • Financing for sustainability • Innovation for acceleration Regional consultation (33 countries), June 2015
  • 20. 20 Thank you very much for your attention