The document discusses the deadly combination of the HIV/AIDS and tuberculosis (TB) pandemics. It states that around 12 million people worldwide are co-infected with HIV and TB, and that each disease makes the other worse. New tools are needed to combat the co-epidemic, including vaccines, diagnostics, and treatments. The Aeras Global TB Vaccine Foundation is working to develop new TB vaccines to help eliminate TB globally by 2050.
This document discusses HIV and TB co-infection. It notes that HIV increases the risk of developing active TB due to immunosuppression. Diagnosing TB is more difficult in HIV patients as sputum smears can be negative and symptoms are atypical. WHO recommends treating TB first before beginning antiretroviral therapy for co-infected patients, and directly observed treatment to ensure adherence. Clinical trials are exploring optimal antiretroviral regimens for co-infected patients.
- There is an estimated 1 million people worldwide who have TB and HIV co-infection, with a high burden in sub-Saharan Africa and Asia.
- People living with HIV are 26-31 times more likely to develop TB than those without HIV. TB is the most common illness in those with HIV and a major cause of HIV-related death.
- Clinical manifestations of TB in those with HIV depend on immune deficiency level, ranging from typical localized TB to atypical disseminated forms with more advanced HIV disease. Diagnosis involves screening algorithms, radiography, sputum smear microscopy, mycobacterial culture, and molecular and serological tests.
This document discusses treatment considerations for patients co-infected with tuberculosis (TB) and HIV. It summarizes evidence on initiating antiretroviral therapy (ART) in patients being treated for TB. Starting ART earlier reduces HIV disease progression and death, but increases the risk of TB-immune reconstitution inflammatory syndrome (IRIS). Later ART initiation reduces IRIS risk, but increases HIV disease progression and death risks. The optimal time to start ART in TB patients may depend on their CD4 count and differs according to the individual's risks.
The document discusses HIV/AIDS and tuberculosis (TB). It provides information on HIV, including how it attacks CD4 cells and weakens the immune system. TB is caused by the bacterium Mycobacterium tuberculosis. HIV increases the risk of active TB for those with latent TB infections. Clinical presentation of TB is often atypical in HIV patients. Proper treatment of both HIV and TB is required to improve prognosis. The case presentation is likely extrapulmonary TB involving the pericardium and lymph nodes based on the symptoms and chest x-ray findings.
The document discusses the need for collaborative programs between HIV and tuberculosis (TB) programs. It notes that HIV is the strongest risk factor for TB and TB is a leading cause of death for people living with HIV. It recommends establishing coordinating bodies between HIV and TB programs to conduct joint planning, monitoring and evaluation. Key collaborative activities include intensified TB case finding, TB preventive therapy, and TB infection control for HIV programs and HIV testing, prevention, care/support and antiretroviral therapy for TB programs. Close collaboration is needed to integrate diagnostic, care and prevention services for people affected by both diseases.
The document discusses the interaction between tuberculosis (TB) and HIV on epidemiological, clinical, and cellular levels. It notes that HIV is the strongest risk factor for reactivation of latent TB infection. Co-infection increases morbidity and mortality as HIV increases the risk of developing active TB disease. A coordinated public health approach is needed that includes intensified case finding, infection control, and isoniazid prophylaxis to address the synergistic relationship between TB and HIV.
This document discusses TB/HIV co-infection, providing information on the global epidemiology, pathogenesis, clinical presentation, diagnosis, and management of TB in HIV patients. Some key points:
- TB is the leading cause of death for people living with HIV globally, with Africa disproportionately affected as rates there continue to rise.
- HIV infection increases the risk of developing active TB due to CD4+ T-cell depletion impairing the immune response to M. tuberculosis. This can lead to atypical clinical presentations and difficulties in diagnosis.
- Diagnosis is challenging as sputum smear-negative TB is more common in HIV patients. Culture remains the gold standard but newer rapid tests like nucleic acid amplification and
The document discusses the deadly combination of the HIV/AIDS and tuberculosis (TB) pandemics. It states that around 12 million people worldwide are co-infected with HIV and TB, and that each disease makes the other worse. New tools are needed to combat the co-epidemic, including vaccines, diagnostics, and treatments. The Aeras Global TB Vaccine Foundation is working to develop new TB vaccines to help eliminate TB globally by 2050.
This document discusses HIV and TB co-infection. It notes that HIV increases the risk of developing active TB due to immunosuppression. Diagnosing TB is more difficult in HIV patients as sputum smears can be negative and symptoms are atypical. WHO recommends treating TB first before beginning antiretroviral therapy for co-infected patients, and directly observed treatment to ensure adherence. Clinical trials are exploring optimal antiretroviral regimens for co-infected patients.
- There is an estimated 1 million people worldwide who have TB and HIV co-infection, with a high burden in sub-Saharan Africa and Asia.
- People living with HIV are 26-31 times more likely to develop TB than those without HIV. TB is the most common illness in those with HIV and a major cause of HIV-related death.
- Clinical manifestations of TB in those with HIV depend on immune deficiency level, ranging from typical localized TB to atypical disseminated forms with more advanced HIV disease. Diagnosis involves screening algorithms, radiography, sputum smear microscopy, mycobacterial culture, and molecular and serological tests.
This document discusses treatment considerations for patients co-infected with tuberculosis (TB) and HIV. It summarizes evidence on initiating antiretroviral therapy (ART) in patients being treated for TB. Starting ART earlier reduces HIV disease progression and death, but increases the risk of TB-immune reconstitution inflammatory syndrome (IRIS). Later ART initiation reduces IRIS risk, but increases HIV disease progression and death risks. The optimal time to start ART in TB patients may depend on their CD4 count and differs according to the individual's risks.
The document discusses HIV/AIDS and tuberculosis (TB). It provides information on HIV, including how it attacks CD4 cells and weakens the immune system. TB is caused by the bacterium Mycobacterium tuberculosis. HIV increases the risk of active TB for those with latent TB infections. Clinical presentation of TB is often atypical in HIV patients. Proper treatment of both HIV and TB is required to improve prognosis. The case presentation is likely extrapulmonary TB involving the pericardium and lymph nodes based on the symptoms and chest x-ray findings.
The document discusses the need for collaborative programs between HIV and tuberculosis (TB) programs. It notes that HIV is the strongest risk factor for TB and TB is a leading cause of death for people living with HIV. It recommends establishing coordinating bodies between HIV and TB programs to conduct joint planning, monitoring and evaluation. Key collaborative activities include intensified TB case finding, TB preventive therapy, and TB infection control for HIV programs and HIV testing, prevention, care/support and antiretroviral therapy for TB programs. Close collaboration is needed to integrate diagnostic, care and prevention services for people affected by both diseases.
The document discusses the interaction between tuberculosis (TB) and HIV on epidemiological, clinical, and cellular levels. It notes that HIV is the strongest risk factor for reactivation of latent TB infection. Co-infection increases morbidity and mortality as HIV increases the risk of developing active TB disease. A coordinated public health approach is needed that includes intensified case finding, infection control, and isoniazid prophylaxis to address the synergistic relationship between TB and HIV.
This document discusses TB/HIV co-infection, providing information on the global epidemiology, pathogenesis, clinical presentation, diagnosis, and management of TB in HIV patients. Some key points:
- TB is the leading cause of death for people living with HIV globally, with Africa disproportionately affected as rates there continue to rise.
- HIV infection increases the risk of developing active TB due to CD4+ T-cell depletion impairing the immune response to M. tuberculosis. This can lead to atypical clinical presentations and difficulties in diagnosis.
- Diagnosis is challenging as sputum smear-negative TB is more common in HIV patients. Culture remains the gold standard but newer rapid tests like nucleic acid amplification and
This document summarizes guidelines for treating HIV-TB coinfection. It notes that India accounts for 10% of the global HIV-TB burden. HIV increases the risk of active TB through depletion of immune cells and reactivation of latent TB. ART reduces this risk but drug interactions with TB treatment can cause toxicity. A key approach is the "3 I's": intensified case finding for TB, isoniazid preventive therapy (IPT) for latent TB, and airborne infection control. IPT for 6 months is recommended to prevent progression to active TB in HIV-positive individuals with no signs of active disease. Managing drug interactions and immune reconstitution inflammatory syndrome (IRIS) is also discussed.
This document provides information about HIV/AIDS and tuberculosis (TB) in South Africa to enhance nursing students' experience at service sites. It discusses transmission, symptoms, diagnosis and treatment of HIV/AIDS and TB. South Africa has the most HIV infections worldwide, especially among young women. TB is highly associated with HIV and a leading cause of death for those infected. The document recommends precautions to prevent transmission and encourages interaction with communities while dismissing stigmas.
HIV infection weakens the immune system by destroying CD4+ T cells, making people more susceptible to developing active tuberculosis. HIV damages the immune system over time by directly infecting and killing T cells. This prolonged destruction of T cells eventually leaves the body unable to control TB infection. As a person's CD4+ count declines due to HIV, they are more likely to develop atypical and disseminated forms of TB that are harder to diagnose. The HIV/TB co-epidemic affects millions worldwide and close monitoring is needed to treat both infections.
1. Early detection of HIV-TB co-infection is challenging but important as TB is a leading cause of death among people living with HIV. New diagnostic approaches like Xpert MTB/RIF can improve detection rates.
2. TB is more difficult to diagnose, spreads faster, and is more deadly in people living with HIV. The risk of developing active TB increases with lower CD4 counts.
3. Screening and testing algorithms along with new tests like Xpert MTB/RIF, LF-LAM, and treatment of latent TB are recommended to reduce the high TB mortality among people living with HIV.
This document discusses the close interlink between tuberculosis (TB) and HIV, noting that TB is a leading cause of HIV-related morbidity and mortality. It explains that HIV increases the risk of developing active TB for those with latent TB infections, and that people living with HIV have a 10-50% increased lifetime risk of developing TB compared to HIV-negative individuals. The document also describes how TB and HIV interact and influence each other, exacerbating the diseases. It provides details on diagnosing and treating co-infections of TB and HIV.
PRESENTATION ON TUBERCULOSIS (TB) AND HUMAN IMMUNODEFICIENCY VIRUS (HIV)Zahra Khan
The document discusses the epidemiology and pathogenesis of tuberculosis (TB) among people living with HIV. Some key points:
- HIV increases the risk of developing active TB due to the weakening of the immune system. About 38% of TB patients in Tanzania are co-infected with HIV.
- The lifetime risk of developing active TB is 30-50% for those co-infected with HIV and TB, compared to 5-10% for HIV-negative individuals.
- Proper screening and treatment of both HIV and TB is important. The preferred first-line antiretroviral therapy regimen for co-infected individuals is TDF+3TC(or FTC)+EFV due to minimal drug interactions
TB/HIV co-infections have risen sharply across Europe between 2011-2015, threatening progress made in reducing TB cases. While TB deaths and cases have decreased and treatment success has increased for most groups, TB/HIV deaths and cases are rising significantly. Drug-resistant TB also remains a major problem, with over half of cases in Europe being multi-drug resistant and about a quarter being extensively drug resistant. Increased efforts are needed across Europe to curb the rise of TB/HIV and improve diagnosis and treatment of drug resistant TB.
This document discusses tuberculosis (TB) in India. It notes that India has the highest TB burden in the world, accounting for nearly 1/5 of global cases. Every year approximately 1.8 million people develop TB in India, of which around 800,000 are new smear-positive cases. India also has the fastest expanding DOTS program for treating TB, which has treated over 7.3 million patients since 1997.
Tuberculosis is a highly infectious disease caused by the bacterium Mycobacterium tuberculosis that typically affects the lungs. It is spread through airborne droplets when people with active TB cough, sneeze or spit. Most infections are asymptomatic and latent, but about 10% of cases progress to active disease. Risk factors include poverty, malnutrition, lack of healthcare, and conditions that weaken the immune system like HIV/AIDS. Globally, TB is one of the top infectious killers and over 95% of cases and deaths are in developing countries.
There are 5 major hepatotropic viruses that can cause viral hepatitis: hepatitis A, B, C, D, and E viruses. Hepatitis A and E viruses are transmitted via the fecal-oral route while hepatitis B, C, and D viruses are transmitted via exposure to infected blood or body fluids. The presentation of viral hepatitis ranges from asymptomatic infection to acute symptomatic hepatitis and even acute liver failure in severe cases. Laboratory tests are used to diagnose viral hepatitis and help determine if infection is acute or chronic. There is no specific treatment for viral hepatitis but supportive care and vaccination can help prevent infection.
This document summarizes key information about tuberculosis (TB), including:
- TB remains a global health problem, infecting around one third of the world's population and killing millions each year. It is one of the top infectious disease killers worldwide.
- The largest number of TB cases occur in Asia, with India and China accounting for over half of all global cases. Sub-Saharan Africa has the highest rates of cases and deaths per capita.
- TB is closely linked to HIV/AIDS, with those coinfected being at much higher risk of falling ill from TB. Over 80% of TB cases among people living with HIV reside in Africa.
This document provides an overview of the epidemiology of HIV/AIDS with recent updates to prevention and treatment programs. It discusses the global and national epidemiology, modes of transmission, clinical manifestations and diagnosis. It summarizes the national AIDS control program in India, including surveillance, counseling/testing services, care/support/treatment. National strategies under NACP-IV are outlined for objectives, key initiatives, services and monitoring. WHO guidelines on treatment initiation, first/second/third line ART regimens, viral load monitoring, post-exposure prophylaxis, and use of co-trimoxazole are summarized.
HIV/AIDS is caused by the human immunodeficiency virus (HIV) which weakens the immune system and leaves the body vulnerable to opportunistic infections. It is transmitted through bodily fluids and has become a global pandemic. As the virus destroys CD4+ T cells over time, it progresses from asymptomatic infection to AIDS, defined by specific infections or a low CD4+ count. Common infections include Pneumocystis pneumonia, tuberculosis, toxoplasmosis, and various cancers like Kaposi's sarcoma. There is no vaccine or cure, but antiretroviral treatment can control the virus.
This document summarizes key information about human immunodeficiency virus (HIV). It was first identified in 1981 and causes AIDS. HIV is a retrovirus that infects and kills CD4+ T cells. Major transmission routes are sexual contact and transmission from mother to child. Untreated infection progresses from primary infection to asymptomatic infection and then symptomatic infection before developing AIDS, which is characterized by opportunistic infections. Common opportunistic infections in people with AIDS include Pneumocystis pneumonia and Kaposi's sarcoma. The document also outlines clinical features, course of infection, and investigations for diagnosing HIV infection.
Human Immunodeficiency Virus (HIV) infects CD4 T cells of the immune system and causes Acquired Immunodeficiency Syndrome (AIDS), resulting in increased susceptibility to opportunistic infections. HIV is transmitted through unprotected sex, sharing needles, or from mother to child. The disease progresses through four stages, from initial infection to AIDS, as CD4 cell counts decline and opportunistic infections develop. Diagnosis involves antibody and viral load testing, while treatment is with antiretroviral therapy to suppress HIV and prevent disease progression.
This document provides guidelines and statistics related to HIV and ART in India. It discusses:
- Global and national HIV prevalence statistics, with over 2 million people living with HIV in India.
- The national response to HIV/AIDS in India, including establishment of organizations and funding for prevention and treatment programs over time.
- Diagnosis of HIV infection, pre-ART care, CD4 count monitoring, and guidelines for primary opportunistic infection prophylaxis.
- Guidelines for initiation of ART based on CD4 count and clinical staging, including first-line ART regimens, management of HIV-TB co-infection, and changes to WHO recommendations over time.
- Potential immune reconstitution inflammatory syndrome (IR
TB and HIV epidemics are closely linked, with each exacerbating the other. People with HIV are at much higher risk of developing active TB disease. TB is also a leading cause of death among people with HIV. Integrated and collaborative efforts are needed globally using the "Three I's" approach of intensified TB case finding, isoniazid preventive therapy, and infection control to reduce the burden of TB among people living with HIV and HIV among TB patients.
This document discusses tuberculosis (TB) and the co-infection of TB and HIV. It notes that globally about 15% of new TB cases occur in HIV positive individuals. In the South-East Asia region, countries like India, Myanmar, Nepal and Thailand have high burdens of TB/HIV co-infection. The study aims to assess knowledge, attitudes and practices regarding TB and TB/HIV co-infection in Nepal to establish a baseline and inform policy. It outlines the objectives, research questions, and definitions that will be used in the study.
Tuberculosis (TB) is a bacterial infection caused by Mycobacterium tuberculosis that most commonly infects the lungs. It can be treated with a combination of anti-TB drugs. TB is spread through airborne droplets when an infected person coughs or sneezes. While latent TB means the immune system has contained the infection, active TB means the person is sick and can spread the infection. Treatment involves a combination of first-line drugs like isoniazid, rifampin and ethambutol over a period of 6-9 months.
This document summarizes the 2015 CDC treatment guidelines for common sexually transmitted diseases. It lists the recommended medications, dosages, and alternative treatments for diseases including bacterial vaginosis, chlamydia, gonorrhea, herpes, trichomoniasis, and others. For each disease, the recommended first-line treatment is provided, as well as alternative options if the first treatment fails or cannot be tolerated. Guidance is given for treating both adults and special populations like pregnant women, infants, and children.
Presented by Leen Meulenbergs
WHO Representative to the European Union and
Executive Manager for Strategic Partnerships (PAR) in the WHO European Union, at the 66th Session of the WHO Regional Committee for Europe.
This document summarizes guidelines for treating HIV-TB coinfection. It notes that India accounts for 10% of the global HIV-TB burden. HIV increases the risk of active TB through depletion of immune cells and reactivation of latent TB. ART reduces this risk but drug interactions with TB treatment can cause toxicity. A key approach is the "3 I's": intensified case finding for TB, isoniazid preventive therapy (IPT) for latent TB, and airborne infection control. IPT for 6 months is recommended to prevent progression to active TB in HIV-positive individuals with no signs of active disease. Managing drug interactions and immune reconstitution inflammatory syndrome (IRIS) is also discussed.
This document provides information about HIV/AIDS and tuberculosis (TB) in South Africa to enhance nursing students' experience at service sites. It discusses transmission, symptoms, diagnosis and treatment of HIV/AIDS and TB. South Africa has the most HIV infections worldwide, especially among young women. TB is highly associated with HIV and a leading cause of death for those infected. The document recommends precautions to prevent transmission and encourages interaction with communities while dismissing stigmas.
HIV infection weakens the immune system by destroying CD4+ T cells, making people more susceptible to developing active tuberculosis. HIV damages the immune system over time by directly infecting and killing T cells. This prolonged destruction of T cells eventually leaves the body unable to control TB infection. As a person's CD4+ count declines due to HIV, they are more likely to develop atypical and disseminated forms of TB that are harder to diagnose. The HIV/TB co-epidemic affects millions worldwide and close monitoring is needed to treat both infections.
1. Early detection of HIV-TB co-infection is challenging but important as TB is a leading cause of death among people living with HIV. New diagnostic approaches like Xpert MTB/RIF can improve detection rates.
2. TB is more difficult to diagnose, spreads faster, and is more deadly in people living with HIV. The risk of developing active TB increases with lower CD4 counts.
3. Screening and testing algorithms along with new tests like Xpert MTB/RIF, LF-LAM, and treatment of latent TB are recommended to reduce the high TB mortality among people living with HIV.
This document discusses the close interlink between tuberculosis (TB) and HIV, noting that TB is a leading cause of HIV-related morbidity and mortality. It explains that HIV increases the risk of developing active TB for those with latent TB infections, and that people living with HIV have a 10-50% increased lifetime risk of developing TB compared to HIV-negative individuals. The document also describes how TB and HIV interact and influence each other, exacerbating the diseases. It provides details on diagnosing and treating co-infections of TB and HIV.
PRESENTATION ON TUBERCULOSIS (TB) AND HUMAN IMMUNODEFICIENCY VIRUS (HIV)Zahra Khan
The document discusses the epidemiology and pathogenesis of tuberculosis (TB) among people living with HIV. Some key points:
- HIV increases the risk of developing active TB due to the weakening of the immune system. About 38% of TB patients in Tanzania are co-infected with HIV.
- The lifetime risk of developing active TB is 30-50% for those co-infected with HIV and TB, compared to 5-10% for HIV-negative individuals.
- Proper screening and treatment of both HIV and TB is important. The preferred first-line antiretroviral therapy regimen for co-infected individuals is TDF+3TC(or FTC)+EFV due to minimal drug interactions
TB/HIV co-infections have risen sharply across Europe between 2011-2015, threatening progress made in reducing TB cases. While TB deaths and cases have decreased and treatment success has increased for most groups, TB/HIV deaths and cases are rising significantly. Drug-resistant TB also remains a major problem, with over half of cases in Europe being multi-drug resistant and about a quarter being extensively drug resistant. Increased efforts are needed across Europe to curb the rise of TB/HIV and improve diagnosis and treatment of drug resistant TB.
This document discusses tuberculosis (TB) in India. It notes that India has the highest TB burden in the world, accounting for nearly 1/5 of global cases. Every year approximately 1.8 million people develop TB in India, of which around 800,000 are new smear-positive cases. India also has the fastest expanding DOTS program for treating TB, which has treated over 7.3 million patients since 1997.
Tuberculosis is a highly infectious disease caused by the bacterium Mycobacterium tuberculosis that typically affects the lungs. It is spread through airborne droplets when people with active TB cough, sneeze or spit. Most infections are asymptomatic and latent, but about 10% of cases progress to active disease. Risk factors include poverty, malnutrition, lack of healthcare, and conditions that weaken the immune system like HIV/AIDS. Globally, TB is one of the top infectious killers and over 95% of cases and deaths are in developing countries.
There are 5 major hepatotropic viruses that can cause viral hepatitis: hepatitis A, B, C, D, and E viruses. Hepatitis A and E viruses are transmitted via the fecal-oral route while hepatitis B, C, and D viruses are transmitted via exposure to infected blood or body fluids. The presentation of viral hepatitis ranges from asymptomatic infection to acute symptomatic hepatitis and even acute liver failure in severe cases. Laboratory tests are used to diagnose viral hepatitis and help determine if infection is acute or chronic. There is no specific treatment for viral hepatitis but supportive care and vaccination can help prevent infection.
This document summarizes key information about tuberculosis (TB), including:
- TB remains a global health problem, infecting around one third of the world's population and killing millions each year. It is one of the top infectious disease killers worldwide.
- The largest number of TB cases occur in Asia, with India and China accounting for over half of all global cases. Sub-Saharan Africa has the highest rates of cases and deaths per capita.
- TB is closely linked to HIV/AIDS, with those coinfected being at much higher risk of falling ill from TB. Over 80% of TB cases among people living with HIV reside in Africa.
This document provides an overview of the epidemiology of HIV/AIDS with recent updates to prevention and treatment programs. It discusses the global and national epidemiology, modes of transmission, clinical manifestations and diagnosis. It summarizes the national AIDS control program in India, including surveillance, counseling/testing services, care/support/treatment. National strategies under NACP-IV are outlined for objectives, key initiatives, services and monitoring. WHO guidelines on treatment initiation, first/second/third line ART regimens, viral load monitoring, post-exposure prophylaxis, and use of co-trimoxazole are summarized.
HIV/AIDS is caused by the human immunodeficiency virus (HIV) which weakens the immune system and leaves the body vulnerable to opportunistic infections. It is transmitted through bodily fluids and has become a global pandemic. As the virus destroys CD4+ T cells over time, it progresses from asymptomatic infection to AIDS, defined by specific infections or a low CD4+ count. Common infections include Pneumocystis pneumonia, tuberculosis, toxoplasmosis, and various cancers like Kaposi's sarcoma. There is no vaccine or cure, but antiretroviral treatment can control the virus.
This document summarizes key information about human immunodeficiency virus (HIV). It was first identified in 1981 and causes AIDS. HIV is a retrovirus that infects and kills CD4+ T cells. Major transmission routes are sexual contact and transmission from mother to child. Untreated infection progresses from primary infection to asymptomatic infection and then symptomatic infection before developing AIDS, which is characterized by opportunistic infections. Common opportunistic infections in people with AIDS include Pneumocystis pneumonia and Kaposi's sarcoma. The document also outlines clinical features, course of infection, and investigations for diagnosing HIV infection.
Human Immunodeficiency Virus (HIV) infects CD4 T cells of the immune system and causes Acquired Immunodeficiency Syndrome (AIDS), resulting in increased susceptibility to opportunistic infections. HIV is transmitted through unprotected sex, sharing needles, or from mother to child. The disease progresses through four stages, from initial infection to AIDS, as CD4 cell counts decline and opportunistic infections develop. Diagnosis involves antibody and viral load testing, while treatment is with antiretroviral therapy to suppress HIV and prevent disease progression.
This document provides guidelines and statistics related to HIV and ART in India. It discusses:
- Global and national HIV prevalence statistics, with over 2 million people living with HIV in India.
- The national response to HIV/AIDS in India, including establishment of organizations and funding for prevention and treatment programs over time.
- Diagnosis of HIV infection, pre-ART care, CD4 count monitoring, and guidelines for primary opportunistic infection prophylaxis.
- Guidelines for initiation of ART based on CD4 count and clinical staging, including first-line ART regimens, management of HIV-TB co-infection, and changes to WHO recommendations over time.
- Potential immune reconstitution inflammatory syndrome (IR
TB and HIV epidemics are closely linked, with each exacerbating the other. People with HIV are at much higher risk of developing active TB disease. TB is also a leading cause of death among people with HIV. Integrated and collaborative efforts are needed globally using the "Three I's" approach of intensified TB case finding, isoniazid preventive therapy, and infection control to reduce the burden of TB among people living with HIV and HIV among TB patients.
This document discusses tuberculosis (TB) and the co-infection of TB and HIV. It notes that globally about 15% of new TB cases occur in HIV positive individuals. In the South-East Asia region, countries like India, Myanmar, Nepal and Thailand have high burdens of TB/HIV co-infection. The study aims to assess knowledge, attitudes and practices regarding TB and TB/HIV co-infection in Nepal to establish a baseline and inform policy. It outlines the objectives, research questions, and definitions that will be used in the study.
Tuberculosis (TB) is a bacterial infection caused by Mycobacterium tuberculosis that most commonly infects the lungs. It can be treated with a combination of anti-TB drugs. TB is spread through airborne droplets when an infected person coughs or sneezes. While latent TB means the immune system has contained the infection, active TB means the person is sick and can spread the infection. Treatment involves a combination of first-line drugs like isoniazid, rifampin and ethambutol over a period of 6-9 months.
This document summarizes the 2015 CDC treatment guidelines for common sexually transmitted diseases. It lists the recommended medications, dosages, and alternative treatments for diseases including bacterial vaginosis, chlamydia, gonorrhea, herpes, trichomoniasis, and others. For each disease, the recommended first-line treatment is provided, as well as alternative options if the first treatment fails or cannot be tolerated. Guidance is given for treating both adults and special populations like pregnant women, infants, and children.
Presented by Leen Meulenbergs
WHO Representative to the European Union and
Executive Manager for Strategic Partnerships (PAR) in the WHO European Union, at the 66th Session of the WHO Regional Committee for Europe.
Strategic directions for the health sector response to viral hepatitis include:
1) Improving surveillance and estimates of disease burden to focus action.
2) Defining essential intervention packages and setting national targets for coverage.
3) Addressing barriers like stigma to make hepatitis services accessible for all populations.
4) Building political commitment and innovative funding approaches for sustainable financing.
5) Prioritizing hepatitis research and rapidly translating findings into practice.
The action plan aims to halt transmission of hepatitis and ensure treatment access for all by 2030.
The WHO Health Emergencies Programme in the European Region focuses on several priority areas:
1) Country health emergency preparedness and International Health Regulations core capacity building.
2) Health emergency information and risk assessment through 24/7 monitoring and early detection of public health events.
3) Emergency operations management for graded health emergencies and coordination of partner responses.
4) Infectious hazard management including prevention and control strategies for high-threat pathogens.
The Programme operates through core services and is working to ensure countries have the capacities for all-hazards health emergency risk management.
Современное лечение ВИЧ : АРТ как профилактика.Contemporary Management of HIV...hivlifeinfo
Contemporary Management of HIV. Antiretroviral Therapy As Prevention.2016
In this downloadable slideset, Kenneth Mayer, MD, and Program Director Eric S. Daar, MD, review key data and optimal approaches for pre- and post-exposure prophylaxis in patients at risk for HIV infection.
Format: Microsoft PowerPoint (.ppt)
File size: 2.13 MB
Presentation by Dr Zsuzsanna Jakab,WHO Regional Director for Europe, at the Third High-level Meeting of the Small Countries Initiative, in Monaco, on 11–12 October 2016
Presentation delivered by Dr Zsuzsanna Jakab, WHO Regional Director for Europe, at the School of Public Health Management (Chisinau, Republic of Moldova, 24 November 2016)
This document provides an overview of primary health care principles including:
- The Alma-Ata Declaration of 1978 established primary health care as the key to achieving Health for All. It defined primary health care and outlined principles.
- Principles of primary health care include equitable distribution of resources, community participation, intersectoral coordination, and use of appropriate technology.
- Primary health care aims to provide essential health services universally and affordably through primary-level facilities as the first point of contact for communities.
- India has evolved its primary health care system over time to strengthen delivery of services in alignment with the goals of Alma-Ata and Health for All.
Fast-track the end of AIDS in the EU - practical evidence-based interventions.
Presentation by: Masoud Dara, WHO Regional Office for Europe
In a two-day meeting under the auspices of the Maltese Presidency of the Council of the European Union (30-31 January 2017), HIV experts from across the European Union discussed how to reverse this trend and how to prepare Europe to achieve the set target of ending AIDS by 2030.
MDR-TB continues to ravage Europe, making it the most affected region globally. Only 50% of MDR-TB patients are detected and half of those successfully treated. This calls for increased access to new TB drugs, faster diagnosis, and patient-centered care as advocated in the new End TB Strategy and European action plan. While TB rates are declining in Europe, nearly 1,000 new cases still occur daily, with high burdens in 18 priority countries where 84% of cases and 90% of deaths occur. MDR rates remain high, underscoring the need for better detection and treatment in Europe.
Presentation by ECDC HIV expert Anastasia Pharris on epidemiological challenges for the HIV response in Europe.
Presented at: 16th European AIDS Conference, 26 October 2017, Milan.
Although HIV is preventable through effective public health measures, significant HIV transmission continues in Europe. In 2015, almost 30 000 people were diagnosed in European Union and European Economic Area Member States; a rate of 6.3 cases in every 100 000 people (when adjusted for reporting delay).
This report, prepared jointly with the WHO Regional Office for Europe, presents data on HIV and AIDS for the whole European Region, including the EU and EEA countries. Analyses are provided for the EU and EEA region.
Presentation during the EU session "Eliminationm of hepatitis B and C in teh EU: challenges and opportunities", at the International Liver Congress (ILC) 2017 in Amsterdam.
Presenter: Erika Duffell, European Centre for Disease Prevention and Control (ECDC)
In 2012, 29,381 new HIV diagnoses were reported in the EU/EEA region, with a rate of 5.8 per 100,000 population. Men who have sex with men accounted for 40.4% of transmissions, while heterosexual contact was 33.8% and injecting drug use was 6.1%. Half of infections were diagnosed at an advanced stage. While HIV levels are low among injecting drug users in most countries, some have seen increases. Interventions must be tailored to local epidemics and focus on testing and treatment to both help individuals and reduce further transmission in vulnerable groups like men who have sex with men.
This document provides a summary of the 2009 AIDS epidemic update published by UNAIDS and the WHO. It finds that the number of people living with HIV globally continues to rise and reached 33.4 million in 2008. An estimated 2.7 million new HIV infections and 2 million AIDS-related deaths occurred in 2008. While the epidemic has stabilized in most regions, prevalence continues to rise in Eastern Europe and Central Asia and parts of Asia. Sub-Saharan Africa remains most heavily affected, accounting for 71% of new infections globally in 2008. The report examines trends by region and finds evidence of successes in HIV prevention in some countries.
The document discusses tuberculosis (TB) in Europe on World TB Day. It notes that while new TB cases are declining by 5% yearly, efforts need to be strengthened to eliminate TB by 2050. Nearly 1000 new cases still occur daily, and Europe is not on track to halve TB mortality by 2015. Multidrug- and extensively drug-resistant TB remain a major problem, with over half of new cases not being detected or successfully treated. The document calls for putting patients at the center of care, developing new drugs with shorter treatment times, improving diagnostics, and increasing funding to eliminate TB in Europe by 2050.
Although HIV is preventable through effective public health measures, significant HIV transmission continues in Europe. In 2014, almost 30 000 people were diagnosed in European Union and European Economic Area Member States. This slide set includes maps, graphs and tables from the 2014 HIV/AIDS surveillance report, published jointly by ECDC and WHO Europe.
Romania’s current tuberculosis (TB) problems illustrate the consequence of what happens when the challenges of such a disease are, for many years, met with lethargy rather than action. The country currently has about 1/4 of all TB cases in the EU and European Economic Area, even though it has just under 4% of the area’s total population. What are the main barriers to addressing TB in Romania? To what extent are there opportunities for change?
Despite notable progress in the past decade, tuberculosis (TB) is still a public health concern in many countries across Europe. The high rates of TB and multidrug-resistant TB outside the European Union/European Economic Area (EU/EEA) are of particular concern, as are the significant number of TB cases among vulnerable populations within the EU/EEA.
This document reports on global progress toward universal access to HIV/AIDS prevention, treatment, and care. Some key points:
- An estimated 34 million people were living with HIV globally in 2010, with sub-Saharan Africa the most affected region at 22.9 million.
- New HIV infections and AIDS-related deaths declined between 2001 and 2010, but progress needs to accelerate to achieve international targets.
- The number of people receiving antiretroviral therapy has increased substantially in low- and middle-income countries, reaching 6.65 million by the end of 2010, but coverage remains inadequate in many areas.
- Preventing mother-to-child transmission has expanded significantly, but more work
- The number of TB cases in the EU/EEA decreased by 30% from 2006 to 2015 while the notification rate decreased by 37% over this period.
- The highest notification rate in 2015 was observed in the 25-44 year old age group. Males had higher notification rates than females in most age groups.
- Treatment success rates for TB cases remained stable around 72-75% from 2005-2014. The treatment success rate for MDR TB cases was lower at 40.4%.
Fast-track the end of AIDS in the EU - practical evidence-based interventions.
Presentation: ECDC Acting Director Dr Andrea Ammon.
a two-day meeting under the auspices of the Maltese Presidency of the Council of the European Union (30-31 January 2017), HIV experts from across the European Union discussed how to reverse this trend and how to prepare Europe to achieve the set target of ending AIDS by 2030.
Fast-track the end of AIDS in the EU - practical evidence-based interventions.
Presentation by: Amanda Mocroft, UCL
In a two-day meeting under the auspices of the Maltese Presidency of the Council of the European Union (30-31 January 2017), HIV experts from across the European Union discussed how to reverse this trend and how to prepare Europe to achieve the set target of ending AIDS by 2030.
Teymur Noori, ECDC
22nd International AIDS Conference, Amsterdam 2018
2018 European African HIV/AIDS & Hepatitis C Community Summit. "Our Voices Matter for a lasting solution!!"
This document discusses emerging infectious diseases and antimicrobial resistance as key issues for health governance in Europe. It provides information on progress made in several areas:
1) Establishing a WHO European action plan to address antimicrobial resistance that has been adopted by all 53 member states.
2) Expanding infectious disease surveillance networks to cover all member states.
3) Collecting region-wide data on antimicrobial use and consumption to support action by countries.
4) Adopting strategies in the European action plan for HIV/AIDS from 2012-2015 to reduce vulnerability and optimize prevention and treatment outcomes.
Fast-track the end of AIDS in the EU - practical evidence-based interventions.
Presentation by: Valerie Delpech, Public Health Engand
In a two-day meeting under the auspices of the Maltese Presidency of the Council of the European Union (30-31 January 2017), HIV experts from across the European Union discussed how to reverse this trend and how to prepare Europe to achieve the set target of ending AIDS by 2030.
Similar to Presentation - TB and HIV infection in the WHO European Region (20)
This document summarizes measles and rubella surveillance data from the WHO European Region from March 2021 to February 2022. It finds that 22 countries reported 222 measles cases, with the majority (87%) occurring in 10 countries including Tajikistan, Turkey, Belgium, and Poland. 107 rubella cases were reported by 12 countries, with 96 cases in 5 countries including Poland, Turkey, Ukraine, and Germany. The data also examines case trends over time and genotypes in an effort to monitor elimination goals for these vaccine-preventable diseases.
This document summarizes reported measles cases in the WHO European Region from March 2021 to February 2022. It shows the total number of measles cases and incidence rate per country over this period. The highest numbers of cases were reported in Poland, Germany, Italy, and Ukraine. Overall, there were 222 measles cases reported in March 2021, rising to a peak of 35 cases in October 2021, before declining to 33 cases in February 2022.
The document summarizes measles and rubella surveillance data from the WHO European Region. It provides data on measles and rubella cases, incidence, genotypes, and vaccination coverage from 2021-2022. The top countries for measles and rubella cases in this period are reported, with Turkey, Poland, and Ukraine among those with the highest numbers of measles cases and Poland reporting the most rubella cases.
The document provides an overview of measles and rubella cases and vaccination coverage in the WHO European Region from 2021-2022. It summarizes measles and rubella data for 2021, including the top 10 countries by cases. Turkey had the most measles cases in 2021 while Poland had the most rubella cases. Vaccination coverage for measles-containing vaccines was over 90% from 2010-2021.
The document summarizes measles and rubella surveillance data from the WHO European Region from December 2020 to November 2021. It finds that 148 measles cases were reported in this period, with the majority (89%) occurring in 11 countries including Turkey, France, Poland, and Belgium. 103 rubella cases were reported in the same period, with over 90% concentrated in 5 countries including Italy, Germany, Turkey, and Ukraine. Overall measles and rubella cases have declined in the region since 2018 but surveillance and vaccination efforts need to remain vigilant to prevent further outbreaks.
Reported measles cases for the period November 2020—October 2021 (data as of 02 December 2021).A monthly summary of the epidemiological data on selected vaccine-preventable diseases in the WHO European Region
The document summarizes measles and rubella surveillance data from the WHO European Region from October 2020 to September 2021. It finds that Turkey, Ukraine, and Poland reported the most measles cases, with Turkey reporting 35 cases. It also finds that Azerbaijan, Germany, Turkey, Ukraine, and Poland reported the most rubella cases, with Poland reporting 47 cases. Overall, measles and rubella cases have decreased in the region since 2019, but ongoing vaccination efforts are still needed to eliminate both diseases.
The document provides information on measles and rubella cases in the WHO European Region from September 2020 to August 2021. It summarizes that Turkey, Ukraine, and Poland reported the most measles cases, while Poland, Ukraine, and Turkey reported the most rubella cases. Overall measles and rubella cases have declined compared to previous years but outbreaks still occur periodically in some countries. The document also provides links to additional measles and rubella surveillance resources on the WHO website.
The document provides an overview of measles and rubella cases in the WHO European Region from August 2020 to July 2021. It summarizes measles and rubella data, including the number of reported cases by country, genotype information, and monthly trends over multiple years. Turkey had the highest number of measles cases while Poland had the most rubella cases. Measles cases were highest among unvaccinated children under 5 years old.
The document summarizes measles and rubella surveillance data from the WHO European Region from July 2020 to June 2021. It finds that for measles, Turkey, Ukraine, Belgium, Poland and France reported the most cases, with Turkey reporting 30 cases. For rubella, Italy, Turkey, Germany, Ukraine and Poland reported most of the 80 total cases. The number of measles cases decreased from 2020 to 2021 while the number of rubella cases remained low. Vaccination coverage and outbreaks varied by country.
The document provides measles and rubella surveillance data for the WHO European Region from May 2020 to April 2021. It shows that:
- Kazakhstan reported the highest number of measles cases, while Poland, France, and others also reported cases.
- For rubella, Poland reported the highest number of cases between May 2020 to April 2021, while Italy, Turkey, Germany and Ukraine also reported cases.
- Both measles and rubella cases were highest in 2020 compared to previous years, though rubella cases remained low overall, with 188 cases reported for 2020.
Uzbekistan and Kazakhstan reported the highest numbers of measles cases between April 2020-March 2021, with 446 and 423 cases respectively. Overall, 1,511 measles cases were reported in this period in the WHO European Region, with 96% occurring in the top 10 reporting countries. For rubella, 86 total cases were reported between April 2020-March 2021, with 97% found in the top 5 countries of Italy, Turkey, Germany, Ukraine, and Poland.
Pictorial and detailed description of patellar instability with sign and symptoms and how to diagnose , what investigations you should go with and how to approach with treatment options . I have presented this slide in my 2nd year junior residency in orthopedics at LLRM medical college Meerut and got good reviews for it
After getting it read you will definitely understand the topic.
BBB and BCF
control the entry of compounds into the brain and
regulate brain homeostasis.
restricts access to brain cells of blood–borne compounds and
facilitates nutrients essential for normal metabolism to reach brain cells
STUDIES IN SUPPORT OF SPECIAL POPULATIONS: GERIATRICS E7shruti jagirdar
Unit 4: MRA 103T Regulatory affairs
This guideline is directed principally toward new Molecular Entities that are
likely to have significant use in the elderly, either because the disease intended
to be treated is characteristically a disease of aging ( e.g., Alzheimer's disease) or
because the population to be treated is known to include substantial numbers of
geriatric patients (e.g., hypertension).
The biomechanics of running involves the study of the mechanical principles underlying running movements. It includes the analysis of the running gait cycle, which consists of the stance phase (foot contact to push-off) and the swing phase (foot lift-off to next contact). Key aspects include kinematics (joint angles and movements, stride length and frequency) and kinetics (forces involved in running, including ground reaction and muscle forces). Understanding these factors helps in improving running performance, optimizing technique, and preventing injuries.
“Environmental sanitation means the art and science of applying sanitary, biological and physical science principles and knowledge to improve and control the environment therein for the protection of the health and welfare of the public”.The overall importance of sanitation are to provide a healthy living environment for everyone, to protect the natural resources (such as surface water, groundwater, soil ), and to provide safety, security and dignity for people when they defecate or urinate .Sanitation refers to public health conditions such as drinking clean water, sewage treatment, etc. All the effective tools and actions that help in keeping the environment clean come under sanitation. Sanitation refers to public health conditions such as drinking clean water, sewage treatment. All the effective tools and actions that help in keeping the environment clean and promotes public health is the necessary in todays life.
Spontaneous Bacterial Peritonitis - Pathogenesis , Clinical Features & Manage...Jim Jacob Roy
In this presentation , SBP ( spontaneous bacterial peritonitis ) , which is a common complication in patients with cirrhosis and ascites is described in detail.
The reference for this presentation is Sleisenger and Fordtran's Gastrointestinal and Liver Disease Textbook ( 11th edition ).
As the world population is aging, Health tourism has become vitally important and will be increased day by day. Because
of the availability of quality health services and more favorable prices as well as to shorten the waiting list for medical
services regionally and internationally. There are some aspects of managing and doing marketing activities in order for
medical tourism to be feasible, in a region called as clustering in a region with main stakeholders groups includes Health
providers, Tourism cluster, etc. There are some related and affecting factors to be considered for the feasibility of medical
tourism within this study such as competitiveness, clustering, Entrepreneurship, SMEs. One of the growth phenomenon
is Health tourism in the city of Izmir and Turkey. The model of five competitive forces of Porter and The Diamond model
that is an economical model that shows the four main factors that affect the competitiveness of a nation and its industries
in this study. The short literature of medical tourism and regional clustering have been mentioned.
CLASSIFICATION OF H1 ANTIHISTAMINICS-
FIRST GENERATION ANTIHISTAMINICS-
1)HIGHLY SEDATIVE-DIPHENHYDRAMINE,DIMENHYDRINATE,PROMETHAZINE,HYDROXYZINE 2)MODERATELY SEDATIVE- PHENARIMINE,CYPROHEPTADINE, MECLIZINE,CINNARIZINE
3)MILD SEDATIVE-CHLORPHENIRAMINE,DEXCHLORPHENIRAMINE
TRIPROLIDINE,CLEMASTINE
SECOND GENERATION ANTIHISTAMINICS-FEXOFENADINE,
LORATADINE,DESLORATADINE,CETIRIZINE,LEVOCETIRIZINE,
AZELASTINE,MIZOLASTINE,EBASTINE,RUPATADINE. Mechanism of action of 2nd generation antihistaminics-
These drugs competitively antagonize actions of
histamine at the H1 receptors.
Pharmacological actions-
Antagonism of histamine-The H1 antagonists effectively block histamine induced bronchoconstriction, contraction of intestinal and other smooth muscle and triple response especially wheal, flare and itch. Constriction of larger blood vessel by histamine is also antagonized.
2) Antiallergic actions-Many manifestations of immediate hypersensitivity (type I reactions)are suppressed. Urticaria, itching and angioedema are well controlled.3) CNS action-The older antihistamines produce variable degree of CNS depression.But in case of 2nd gen antihistaminics there is less CNS depressant property as these cross BBB to significantly lesser extent.
4) Anticholinergic action- many H1 blockers
in addition antagonize muscarinic actions of ACh. BUT IN 2ND gen histaminics there is Higher H1 selectivitiy : no anticholinergic side effects
- Video recording of this lecture in English language: https://youtu.be/RvdYsTzgQq8
- Video recording of this lecture in Arabic language: https://youtu.be/ECILGWtgZko
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Osvaldo Bernardo Muchanga-GASTROINTESTINAL INFECTIONS AND GASTRITIS-2024.pdfOsvaldo Bernardo Muchanga
GASTROINTESTINAL INFECTIONS AND GASTRITIS
Osvaldo Bernardo Muchanga
Gastrointestinal Infections
GASTROINTESTINAL INFECTIONS result from the ingestion of pathogens that cause infections at the level of this tract, generally being transmitted by food, water and hands contaminated by microorganisms such as E. coli, Salmonella, Shigella, Vibrio cholerae, Campylobacter, Staphylococcus, Rotavirus among others that are generally contained in feces, thus configuring a FECAL-ORAL type of transmission.
Among the factors that lead to the occurrence of gastrointestinal infections are the hygienic and sanitary deficiencies that characterize our markets and other places where raw or cooked food is sold, poor environmental sanitation in communities, deficiencies in water treatment (or in the process of its plumbing), risky hygienic-sanitary habits (not washing hands after major and/or minor needs), among others.
These are generally consequences (signs and symptoms) resulting from gastrointestinal infections: diarrhea, vomiting, fever and malaise, among others.
The treatment consists of replacing lost liquids and electrolytes (drinking drinking water and other recommended liquids, including consumption of juicy fruits such as papayas, apples, pears, among others that contain water in their composition).
To prevent this, it is necessary to promote health education, improve the hygienic-sanitary conditions of markets and communities in general as a way of promoting, preserving and prolonging PUBLIC HEALTH.
Gastritis and Gastric Health
Gastric Health is one of the most relevant concerns in human health, with gastrointestinal infections being among the main illnesses that affect humans.
Among gastric problems, we have GASTRITIS AND GASTRIC ULCERS as the main public health problems. Gastritis and gastric ulcers normally result from inflammation and corrosion of the walls of the stomach (gastric mucosa) and are generally associated (caused) by the bacterium Helicobacter pylor, which, according to the literature, this bacterium settles on these walls (of the stomach) and starts to release urease that ends up altering the normal pH of the stomach (acid), which leads to inflammation and corrosion of the mucous membranes and consequent gastritis or ulcers, respectively.
In addition to bacterial infections, gastritis and gastric ulcers are associated with several factors, with emphasis on prolonged fasting, chemical substances including drugs, alcohol, foods with strong seasonings including chilli, which ends up causing inflammation of the stomach walls and/or corrosion. of the same, resulting in the appearance of wounds and consequent gastritis or ulcers, respectively.
Among patients with gastritis and/or ulcers, one of the dilemmas is associated with the foods to consume in order to minimize the sensation of pain and discomfort.
Giloy in Ayurveda - Classical Categorization and SynonymsPlanet Ayurveda
Giloy, also known as Guduchi or Amrita in classical Ayurvedic texts, is a revered herb renowned for its myriad health benefits. It is categorized as a Rasayana, meaning it has rejuvenating properties that enhance vitality and longevity. Giloy is celebrated for its ability to boost the immune system, detoxify the body, and promote overall wellness. Its anti-inflammatory, antipyretic, and antioxidant properties make it a staple in managing conditions like fever, diabetes, and stress. The versatility and efficacy of Giloy in supporting health naturally highlight its importance in Ayurveda. At Planet Ayurveda, we provide a comprehensive range of health services and 100% herbal supplements that harness the power of natural ingredients like Giloy. Our products are globally available and affordable, ensuring that everyone can benefit from the ancient wisdom of Ayurveda. If you or your loved ones are dealing with health issues, contact Planet Ayurveda at 01725214040 to book an online video consultation with our professional doctors. Let us help you achieve optimal health and wellness naturally.
9. 9
What is new in the new TB action plan?
• Scale-up of rapid diagnosis
• Expanded patient-centred care models
• Shorter, more effective treatment regimens and new
medicines
• Research for new tools
• Intersectoral approach to inequities
10. 10
TB action plan for the WHO European Region
2016–2020
• 3.1 million lives will have been saved
• 1.4 million TB patients will have been cured
• 1.7 million new cases of all forms of TB
will have been prevented
• US$ 48 billion will have been saved
11. 11
Less progress in prevention and control of HIV infection in
the WHO European Region
Despite progress in implementation
of the European action plan for
HIV/AIDS 2012–2015 and more
people on treatment, the HIV
epidemic in this Region is still
increasing.
12. 12
0
20
40
60
80
100
120
140
160
2004 2005 2006 2007 2008 2009 2010 2011 2012 2013
Thousands
WHO European Region
East
West
Centre
WHO European Region
Centre
West
East
Newly diagnosed HIV infections, WHO European Region,
2004–2013
14. 14
Populations disproportionately affected
• People who inject drugs (and their sexual
partners)
• Men who have sex with men
• Sex workers
• Transgender people
• Prisoners
• Migrants
15. 15
Late diagnoses in Europe
WHO European Region:
Percentages of new cases of HIV
infection with CD4 cell counts
< 350/mm3 and < 200/mm3 at
diagnosis, 2013
Source: ECDC/WHO (2014). HIV/AIDS Surveillance in Europe, 2013
49%
27%
16. 16
East:
Percentages of new cases of HIV infection
with CD4 cell count < 350/mm3 at
diagnosis, by transmission mode, 2013
Late diagnoses in eastern Europe
17. 17
Treatment gap
People with HIV infection receiving antiretroviral therapy (ART) in Europe, 2009–2013
0
200
400
600
800
1000
1200
1400
1600
1800
2000
2009 2010 2011 2012 2013
Thousands
ART western and central Europe
ART eastern Europe
Cumulative HIV cases
26%↑
124%↑
41%↑
18. 18
Prevention of mother-to-child transmission
14%
37%
67%
75%
81%
92%
75%
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%
Eastern Mediterranean Region
South-East Asia Region
Western Pacific Region
African Region
Region of the Americas
European Region
Global
Percentage of pregnant women living with HIV
infection in low- and middle-income countries who
received ART, globally and by WHO region, 2014
19. 19
Global health sector strategies on HIV infection, viral
hepatitis and STIs, 2016–2021
http://www.who.int/hiv/strategy2016-2021/en/
Strategic directions:
• Information for focus and accountability
• Interventions for impact
• Delivery for quality and equity
• Financing for sustainability
• Innovation for acceleration Regional
consultation
(33 countries),
June 2015