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Multiple
Pregnancy
PRESENTED BY
MITAL S PATEL
LECTURER CL II
GCON ,BHAVNAGAR
Definition
A multiple pregnancy is a pregnancy in
which more than one fetus develops in the
uterus at the same time. Multiple pregnancies
occur in 1–2% of pregnancies.
Simultaneous development of two fetuses
(twins) is commonest although rare,
development of three fetuses (triplets), four
fetuses (quintuplets) or six fetuses (sextuplets)
may also occur.
Incidence
TWINS 1:80
TRIPLETS 1:802
QUADRIPLETS 1:803
Monozygotic Twins:
• It is around 33% or 1/3 of all twins.
• It results from fertilization of single ovum by
one sperm.
• Two embryo will develop and closed by single
chorion, single placenta , two seperate
amniotic sac.
Monozygotic Twins:
Dizygotic Twins
• Most common represents 2/3 of cases.
• Fertilization of more than one egg by more
than one sperm.
• Non identical ,may be of different sex.
• Two chorion and two amnion.
• Placenta may be separate or fused.
Dizygotic Twins
Difference:
Characteristic Monozygotic Dizygotic
Placenta One with vascular
communication
Two may be fused but
with no vascular
communication
Membrane 2 amnion & 1 chorion 2 amnion & 2 chorion
Sex Always same Same/ different
Genetic feature Same Different
Abo-Rh Same Different
Finger print Different Different
Skin grafting Acceptance Rejection
Follow up Usually identical Not identical
Difference:
Etiology
• Hereditary  mother important than father.
• Age  peak at 37 years of age.
• Parity  increase more than six times.
• Ovulation inducing drug
Diagnosis
1. History.
2. Clinical Examination.
3. Investigations.
History
• Family history.
• Advanced age.
• High parity.
• Medication.
Clinical Examination
• Symptoms:
– minor ailments aggravated, increased nausea and
vomiting in early months
– Cardio-respiratory embarrassment which is in later
months palpitation or shortness of breath
– Tendency of swelling of legs
– Unusual rate of abdominal enlargement
• General Examination:
– Prevalence of Anemia, unusual weight gain not
explained by preeclampsia or obesity
Continue….
• Abdominal Examination-
– Inspection: Barrel shaped and unduly enlarged abdomen
– Palpation: The height of uterus is more than period of
amenorrhea. The girth of abdomen at the level of umbilicus
is more than the normal average at term (100 cms.) Fetal
bulk seems disproportionately larger. Palpation of too many
fetal parts
– Auscultation: 2 FHS at difference of 10 beats / min are
heard by two observers at two sites.
• Internal examination: In some cases, one head is felt deep in
the pelvis, while other one is located by abdominal
examination.
Continue….
• Investigation:
– Sonography: two gestational sac as early as 5
to 6 wks.
– Chorionicity of the placenta
– Radiography: it’s done after 30 wks to confirm
diagnosis and to diagnose triplet & conjoint
twins.
– Biochemical tests
Differential Diagnosis:
• Hydramnios
• Big baby
• Fibroid or ovarian tumors with pregnancy
• Ascitis with pregnancy
COMPLICATION OF MULTIPLE
PREGNANCIES
Maternal Fetal
Nausea ,vomiting Abortion
Anemia Vanishing twins
PIH Preterm Birth
Polyhydramnions/
oligohydramnios
Fetal anomalies
Preterm labor Discordant growth
Malpresentation Intrauterine death of one fetus
APH Twin transfusion syndrome
Mechanical distress Cord prolapsed
Prolong labor Locked twins
Operative interference Increased Perinatal mortality
PPH ---------
Locked twins
Complication Of Monochorionic
Twins
• Twin Transfusion Syndrome
• Conjoin Twin
Conjoined Twins
• Anterior (thoracopagus)
• Posterior (pygopagus)
• Cephalic (craniopagus)
• Caudal (ischiopagus)
Conjoined Twins
THORACOPGUS
WITH
OMPHALOCELE
SHARING A
HEART AND A
LIVER
Conjoined Twins
CRANIOPAGUS BUT
ACTUALLY
CRANIOTHORACOPAGUS
(SIAMISE TWINS)
Antenatal Management
Advice:
• Diet
• Increased rest
• Supplement therapy
• Interval of antenatal visit
• Fetal surveillance
Antenatal Management
Hospitalization:
• Routine :Rest improves utero-placental
circulation. This results in
–Increased birth weight of babies
–Prolongation of the duration of pregnancy
• Emergency : Development of complicating
factors necessitates urgent admission
irrespective of the period of gestation.
MANAGEMENT DURING LABOR
THANK YOU

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Ppt multiple pregnancy