A new technique improves the sensitivity of PCR pathogen detection by increasing the target organism's cells in a sample before genetic amplification, allowing detection of pathogens at lower levels. Tests using cell-free fetal DNA from a mother's blood to determine the fetus's sex are often effective and provide an alternative to invasive testing, allowing for early detection of sex-linked disorders. The advances in molecular diagnostics discussed could help improve early disease detection and reduce risks of medical procedures.
Tests That Use DNA from Mother’s Blood to Determine Sex of Fetus Often Effective and Genetic Analysis of Amniotic Fluid Shows Promise for Monitoring Fetal Development
Dr Catherine Mercer and Dr Frank Ratcliff - The 100,000 Genome Project - Jan ...onthewight
The 100,000 Genomes Project will sequence 100,000 genomes from around 70,000 people.
Participants are NHS patients with a rare disease, plus their families, and patients with cancer. Significantly, this is currently the largest national sequencing project of its kind in the world.
This talk explores the project, and ask the question; “Would you have your genome sequenced?”
Tests That Use DNA from Mother’s Blood to Determine Sex of Fetus Often Effective and Genetic Analysis of Amniotic Fluid Shows Promise for Monitoring Fetal Development
Dr Catherine Mercer and Dr Frank Ratcliff - The 100,000 Genome Project - Jan ...onthewight
The 100,000 Genomes Project will sequence 100,000 genomes from around 70,000 people.
Participants are NHS patients with a rare disease, plus their families, and patients with cancer. Significantly, this is currently the largest national sequencing project of its kind in the world.
This talk explores the project, and ask the question; “Would you have your genome sequenced?”
Dr. Jim Shelton of USAID discusses the long-acting reversible hormonal contraceptive DMPA (depot medroxyprogesterone acetate) and addresses concerns about whether or not it increases the risk of HIV acquisition.
Detection and classification of plant disease using image analysis and machine learning. Plant images acquired from a mobile hand-held device are analysed to predict the type and magnitude of disease afflicting the plant.
Dr. Jim Shelton of USAID discusses the long-acting reversible hormonal contraceptive DMPA (depot medroxyprogesterone acetate) and addresses concerns about whether or not it increases the risk of HIV acquisition.
Detection and classification of plant disease using image analysis and machine learning. Plant images acquired from a mobile hand-held device are analysed to predict the type and magnitude of disease afflicting the plant.
Plant - Pathogen Interaction and Disease DevelopmentKK CHANDEL
Plant diseases are the result of infection by any living organisms that adversely affect the growth, development, physiological functioning and productivity of a plant, manifesting outwardly as visible symptoms.
Molecular basis of plant resistance and defense responses to pathogensSenthil Natesan
In response to pathogen attack, plants have evolved sophisticated defense mechanisms to delay or arrest pathogen growth.Unlike animals, plants lack a circulating immune system recognizing microbial pathogens. Plant cells are more autonomous in their defense mechanisms and rely on the innate immune capacity of each cell and systemic signals that disseminate from infection sites (Jones and Dangl, 2006). Plant innate immunity consists of preformed physical and chemical barriers (such as leaf hairs, rigid cell walls, pre-existing antimicrobial compounds) and induced defenses. Should an invading microbe successfully breach the pre-formed barriers, it may be recognized by the plant, resulting in the activation of cellular defense responses that stop or restrict further development of the invader.
Application of Biotechnology In Medicine By Anila Rani Pullaguraanilarani
Biotechnology is a very huge field and its applications are used in a variety of fields of science such as agriculture and medicine. Medicine is by means of biotechnology techniques so much in diagnosing and treating dissimilar diseases. It also gives opportunity for the populace to defend themselves from hazardous diseases.
2nd Epigenetics Discovery congress - Latest agendaTony Couch
Advancements in Epigenetics have certainly given us huge breakthroughs in drug discovery, development and effective diagnosis of diseases. Scientists are working towards making new developments and address challenges in epigenetics for cancer, neurodegenerative diseases and other ailments. The Epigenetics Discovery Congress will provide a platform to such scientists to present their work, learn what their peers are doing, share experiences and overcome challenges that the industry is facing.....
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
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Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?
Plegable Biología Molecular
1. New Technique Improves Sensitivity of PCR Pathogen Detection. AND Tests That Use DNA from Mother’s Blood to Determine Sex of Fetus Often Effective. By Cristina Cruz Agudelo Medicine student UPB Medellin
5. New Technique Improves Sensitivity of PCR Pathogen Detection. Science Daily April 22, 2011 MOLECULAR BIOLOGY
6. New Technique Improves Sensitivity of PCR Pathogen Detection. Science Daily April 22, 2011 MOLECULAR BIOLOGY The diagnostic plant diseases that can cause yield losses and diminished markets among other economic harm. The test's ability to obtain a "genetic fingerprint" conclusively identifying a culprit pathogen hinges on there being a minimum number of its cells.
7. MOLECULAR BIOLOGY New Technique Improves Sensitivity of PCR Pathogen Detection. Science Daily April 22, 2011 preliminary step called Growth-promoting agar or liquid media to increase the number of a target organism's cells in a sample prior to amplification of genetic material.
8. MOLECULAR BIOLOGY New Technique Improves Sensitivity of PCR Pathogen Detection. Science Daily April 22, 2011 Increase sensitivity by 100- to 1000-fold over conventional PCR methods Stops substances called inhibitors from interfering with the action of a key enzyme
9. MOLECULAR BIOLOGY New Technique Improves Sensitivity of PCR Pathogen Detection. Science Daily April 22, 2011 PERSONAL OPINION These studies applied to human medicine, to help early detection of latent diseases in the body, using methods that improve current techniques.
10. MOLECULAR BIOLOGY Tests That Use DNA from Mother’s Blood to Determine Sex of Fetus Often Effective Science Daily August 9, 2011
11. MOLECULAR BIOLOGY Tests That Use DNA from Mother’s Blood to Determine Sex of Fetus Often Effective Science Daily August 9, 2011 Important alternative to invasive cytogenetic determination, Noninvasive prenatal determination of fetal sex
12. MOLECULAR BIOLOGY Tests That Use DNA from Mother’s Blood to Determine Sex of Fetus Often Effective Science Daily August 9, 2011 cell-free fetal DNA from Mother’s Blood some heritable disorders
13. MOLECULAR BIOLOGY Tests That Use DNA from Mother’s Blood to Determine Sex of Fetus Often Effective Science Daily August 9, 2011 Detect Y chromosome sequences within maternal samples this "technology can be useful in clinical settings for early detection of fetuses at risk for sex-linked disorders requiring follow-up testing”.
14. MOLECULAR BIOLOGY It's exciting to see the medicine to serve patients and see how we reduce the risks of the procedures that we as future Doctors will improve the quality of life of mothers. Tests That Use DNA from Mother’s Blood to Determine Sex of Fetus Often Effective Science Daily August 9, 2011 PERSONAL OPINION
16. MEDICAL UTILITY MOLECULAR MEDICINE EVERY DAY BRINGS NEW AND TRANSCENDENTAL ADVANCES TO HUMANS
17. MEDICAL UTILITY EARLY DIAGNOSIS EFFECTIVE AND MOLECULAR TREATMENT ENABLING EFFECTIVE
18. MEDICAL UTILITY INTERVENTIONS AND INCREASINGLY LESS INVASIVE TO PREEMPT THE APPEARANCE OF SIGNS AND SYMPTOMS OF DIFFERENT DISEASES HAVE BEATEN TO HUMANITY.
