Tests That Use DNA from Mother’s Blood to Determine Sex of Fetus Often Effective and Genetic Analysis of Amniotic Fluid Shows Promise for Monitoring Fetal Development
Many pregnant women experience symptoms that suggest preterm labor. These may include uterine contractions, changes in vaginal discharge, backaches, pelvic pressure, cramping, and cervical dilation. However, not all symptomatic women will actually have a preterm delivery. The majority will go on to deliver at term.
Preimplantation Genetic Diagnosis (PGD)/Screening (PGS) With IVFKaberi Banerjee
Pre-implantation genetic Screening (PGS) or Pre-implantation genetic diagnosis (PGD) plays an important role in increasing the chances of pregnancy for infertile couples.
Preimplantation genetic diagnosis (PGD) is a procedure used to diagnose embryos for known genetic disorders that both the patients and partners.
Read more: https://www.advancefertility.in/preimplantation-genetic-diagnosis-pgd-pgs-with-ivf/
Multicenter screening for pre-eclampsia by maternal factors and biomarkers at 11–13 weeks' gestation: comparison with NICE guidelines and ACOG recommendations
N. O'Gorman, D. Wright, L. C. Poon, D. L. Rolnik, A. Syngelaki, M. de Alvarado, I. F. Carbone, V. Dutemeyer, M. Fiolna, A. Frick, N. Karagiotis, S. Mastrodima, C. de Paco Matallana, G. Papaioannou, A. Pazos, W. Plasencia, K. H. Nicolaides
Volume 49, Issue 6, Pages 756–760
Slides prepared by Dr Fiona Brownfoot (UOG Editor-for-Trainees)
Read the free-access article: http://onlinelibrary.wiley.com/doi/10.1002/uog.17455/full
Increased nuchal translucency thickness and risk of neurodevelopmental disorders
S. G. Hellmuth, L. H. Pedersen, C. B. Miltoft, O. B. Petersen, S. Kjærgaard, C. Ekelund, A. Tabor
Volume 49, Issue 5; Date: May (pages 592–598)
Slides prepared by Dr Maddalena Morlando (UOG Editors-for-Trainees)
Link to free-access article: http://onlinelibrary.wiley.com/doi/10.1002/uog.15961/full
Perinatal and long-term outcomes in fetuses diagnosed with isolated unilateral ventriculomegaly: systemic review and meta-analysis
C. Scala, A. Familiari, A. Pinas, A.T. Papageorghiou, A. Bhide, B. Thilaganathan, A. Khalil
Volume 49, Issue 4, Date: April (pages 450–459)
Slides prepared by Dr Yael Raz (UOG Editor-for-Trainees)
Link to free-access article: http://onlinelibrary.wiley.com/doi/10.1002/uog.15943/full
PGD combines advances in Molecular genetics and in assisted reproductive technology and is conducted before the embryo is placed inside the womb of the woman.Pre implantation genetic diagnosis was introduced to prevent the inheritance of sex linked diseases
Many pregnant women experience symptoms that suggest preterm labor. These may include uterine contractions, changes in vaginal discharge, backaches, pelvic pressure, cramping, and cervical dilation. However, not all symptomatic women will actually have a preterm delivery. The majority will go on to deliver at term.
Preimplantation Genetic Diagnosis (PGD)/Screening (PGS) With IVFKaberi Banerjee
Pre-implantation genetic Screening (PGS) or Pre-implantation genetic diagnosis (PGD) plays an important role in increasing the chances of pregnancy for infertile couples.
Preimplantation genetic diagnosis (PGD) is a procedure used to diagnose embryos for known genetic disorders that both the patients and partners.
Read more: https://www.advancefertility.in/preimplantation-genetic-diagnosis-pgd-pgs-with-ivf/
Multicenter screening for pre-eclampsia by maternal factors and biomarkers at 11–13 weeks' gestation: comparison with NICE guidelines and ACOG recommendations
N. O'Gorman, D. Wright, L. C. Poon, D. L. Rolnik, A. Syngelaki, M. de Alvarado, I. F. Carbone, V. Dutemeyer, M. Fiolna, A. Frick, N. Karagiotis, S. Mastrodima, C. de Paco Matallana, G. Papaioannou, A. Pazos, W. Plasencia, K. H. Nicolaides
Volume 49, Issue 6, Pages 756–760
Slides prepared by Dr Fiona Brownfoot (UOG Editor-for-Trainees)
Read the free-access article: http://onlinelibrary.wiley.com/doi/10.1002/uog.17455/full
Increased nuchal translucency thickness and risk of neurodevelopmental disorders
S. G. Hellmuth, L. H. Pedersen, C. B. Miltoft, O. B. Petersen, S. Kjærgaard, C. Ekelund, A. Tabor
Volume 49, Issue 5; Date: May (pages 592–598)
Slides prepared by Dr Maddalena Morlando (UOG Editors-for-Trainees)
Link to free-access article: http://onlinelibrary.wiley.com/doi/10.1002/uog.15961/full
Perinatal and long-term outcomes in fetuses diagnosed with isolated unilateral ventriculomegaly: systemic review and meta-analysis
C. Scala, A. Familiari, A. Pinas, A.T. Papageorghiou, A. Bhide, B. Thilaganathan, A. Khalil
Volume 49, Issue 4, Date: April (pages 450–459)
Slides prepared by Dr Yael Raz (UOG Editor-for-Trainees)
Link to free-access article: http://onlinelibrary.wiley.com/doi/10.1002/uog.15943/full
PGD combines advances in Molecular genetics and in assisted reproductive technology and is conducted before the embryo is placed inside the womb of the woman.Pre implantation genetic diagnosis was introduced to prevent the inheritance of sex linked diseases
Reproductive Genetics: Introduction to Genetic Testing Optionskanew396
GenomeSmart can help you navigate the different reproductive genetic testing options to allow you to make informed decisions for the health of yourself and your family.
The importance of prenatal genetic screeningTia-Nia Drayton.docxoreo10
The importance of prenatal genetic screening
Tia-Nia Drayton
Institution:
Date:
Prenatal genetic testing is a medical procedure that allows the pregnant mother to determine her chances of giving birth to a baby with a genetic disorder. The genetic disorders are usually as a result of abnormalities in the chromosome components leading to conditions such as Downs Syndrome Trisomy and Trisomy-8. This procedure informs the actions of the mother to be, in case the fetus is found with any deformity which can vary severity. The problem, however, is that prenatal genetic testing has faced a myriad of ethical and moral debates with individuals arguing that they tend to be invasive and also add emotional burden to the expectant mother. Therefore, the purpose of this paper is to highlight the importance of prenatal testing due to the evidence-based benefits associated with it. Prenatal testing is critical for every mother, more so, the high-risk cases, because it places them a better position to handle any issue, besides advancements in science and technology, have made the risks negligible.
The benefits of prenatal genetic testing
Advanced age adds a significant risk to the reproductive status of a woman. In this context, as a woman reaches her menopausal stage (35 years or older), the likelihood of giving birth to an infant with chromosomal disorders increases. In case a woman at this age range falls pregnant, undertaking a prenatal genetic testing will be very useful in determining the condition of the fetus. It also further informs the action that will be taken by the mother after the test results indicate a disorder. It also allows the parents to be emotionally and financially prepared to handle the caring of the infant should the pregnancy be allowed to advance. However, the downside is that this has propagated termination of pregnancies. According to Mansfield et al. (1999), it was found that termination rates increased by, for instance, 92 % after a prenatal diagnosis of Down syndrome.
The parents have more say in the kind of testing they would like to undertake. Today advancements have been made in genetic testing which offers a wide variety genetic markers. Depending on the preferences of the parents, they can choose the markers which indicate the conditions which their pre-born infants will be predisposed. This also protects the privacy of the parents from scrutiny. Jong et al.(2016) highlights the current advancements which are available to pregnant mothers which include: a)Rapid aneuploidy detection, this is found in developed countries and is used to identify any abnormalities with microscopically visible chromosomes including numerical or structural status, deletions, and duplications; b)prenatal ultrasound, this is performed during the second trimester and allows the physician to identifies any abnormalities in the fetus’ structure but also any other genetic disorders; c)genome-wide molecular testing, this t ...
Key Trends Shaping the Future of Infrastructure.pdfCheryl Hung
Keynote at DIGIT West Expo, Glasgow on 29 May 2024.
Cheryl Hung, ochery.com
Sr Director, Infrastructure Ecosystem, Arm.
The key trends across hardware, cloud and open-source; exploring how these areas are likely to mature and develop over the short and long-term, and then considering how organisations can position themselves to adapt and thrive.
Dev Dives: Train smarter, not harder – active learning and UiPath LLMs for do...UiPathCommunity
💥 Speed, accuracy, and scaling – discover the superpowers of GenAI in action with UiPath Document Understanding and Communications Mining™:
See how to accelerate model training and optimize model performance with active learning
Learn about the latest enhancements to out-of-the-box document processing – with little to no training required
Get an exclusive demo of the new family of UiPath LLMs – GenAI models specialized for processing different types of documents and messages
This is a hands-on session specifically designed for automation developers and AI enthusiasts seeking to enhance their knowledge in leveraging the latest intelligent document processing capabilities offered by UiPath.
Speakers:
👨🏫 Andras Palfi, Senior Product Manager, UiPath
👩🏫 Lenka Dulovicova, Product Program Manager, UiPath
Builder.ai Founder Sachin Dev Duggal's Strategic Approach to Create an Innova...Ramesh Iyer
In today's fast-changing business world, Companies that adapt and embrace new ideas often need help to keep up with the competition. However, fostering a culture of innovation takes much work. It takes vision, leadership and willingness to take risks in the right proportion. Sachin Dev Duggal, co-founder of Builder.ai, has perfected the art of this balance, creating a company culture where creativity and growth are nurtured at each stage.
State of ICS and IoT Cyber Threat Landscape Report 2024 previewPrayukth K V
The IoT and OT threat landscape report has been prepared by the Threat Research Team at Sectrio using data from Sectrio, cyber threat intelligence farming facilities spread across over 85 cities around the world. In addition, Sectrio also runs AI-based advanced threat and payload engagement facilities that serve as sinks to attract and engage sophisticated threat actors, and newer malware including new variants and latent threats that are at an earlier stage of development.
The latest edition of the OT/ICS and IoT security Threat Landscape Report 2024 also covers:
State of global ICS asset and network exposure
Sectoral targets and attacks as well as the cost of ransom
Global APT activity, AI usage, actor and tactic profiles, and implications
Rise in volumes of AI-powered cyberattacks
Major cyber events in 2024
Malware and malicious payload trends
Cyberattack types and targets
Vulnerability exploit attempts on CVEs
Attacks on counties – USA
Expansion of bot farms – how, where, and why
In-depth analysis of the cyber threat landscape across North America, South America, Europe, APAC, and the Middle East
Why are attacks on smart factories rising?
Cyber risk predictions
Axis of attacks – Europe
Systemic attacks in the Middle East
Download the full report from here:
https://sectrio.com/resources/ot-threat-landscape-reports/sectrio-releases-ot-ics-and-iot-security-threat-landscape-report-2024/
Kubernetes & AI - Beauty and the Beast !?! @KCD Istanbul 2024Tobias Schneck
As AI technology is pushing into IT I was wondering myself, as an “infrastructure container kubernetes guy”, how get this fancy AI technology get managed from an infrastructure operational view? Is it possible to apply our lovely cloud native principals as well? What benefit’s both technologies could bring to each other?
Let me take this questions and provide you a short journey through existing deployment models and use cases for AI software. On practical examples, we discuss what cloud/on-premise strategy we may need for applying it to our own infrastructure to get it to work from an enterprise perspective. I want to give an overview about infrastructure requirements and technologies, what could be beneficial or limiting your AI use cases in an enterprise environment. An interactive Demo will give you some insides, what approaches I got already working for real.
LF Energy Webinar: Electrical Grid Modelling and Simulation Through PowSyBl -...DanBrown980551
Do you want to learn how to model and simulate an electrical network from scratch in under an hour?
Then welcome to this PowSyBl workshop, hosted by Rte, the French Transmission System Operator (TSO)!
During the webinar, you will discover the PowSyBl ecosystem as well as handle and study an electrical network through an interactive Python notebook.
PowSyBl is an open source project hosted by LF Energy, which offers a comprehensive set of features for electrical grid modelling and simulation. Among other advanced features, PowSyBl provides:
- A fully editable and extendable library for grid component modelling;
- Visualization tools to display your network;
- Grid simulation tools, such as power flows, security analyses (with or without remedial actions) and sensitivity analyses;
The framework is mostly written in Java, with a Python binding so that Python developers can access PowSyBl functionalities as well.
What you will learn during the webinar:
- For beginners: discover PowSyBl's functionalities through a quick general presentation and the notebook, without needing any expert coding skills;
- For advanced developers: master the skills to efficiently apply PowSyBl functionalities to your real-world scenarios.
Smart TV Buyer Insights Survey 2024 by 91mobiles.pdf91mobiles
91mobiles recently conducted a Smart TV Buyer Insights Survey in which we asked over 3,000 respondents about the TV they own, aspects they look at on a new TV, and their TV buying preferences.
Search and Society: Reimagining Information Access for Radical FuturesBhaskar Mitra
The field of Information retrieval (IR) is currently undergoing a transformative shift, at least partly due to the emerging applications of generative AI to information access. In this talk, we will deliberate on the sociotechnical implications of generative AI for information access. We will argue that there is both a critical necessity and an exciting opportunity for the IR community to re-center our research agendas on societal needs while dismantling the artificial separation between the work on fairness, accountability, transparency, and ethics in IR and the rest of IR research. Instead of adopting a reactionary strategy of trying to mitigate potential social harms from emerging technologies, the community should aim to proactively set the research agenda for the kinds of systems we should build inspired by diverse explicitly stated sociotechnical imaginaries. The sociotechnical imaginaries that underpin the design and development of information access technologies needs to be explicitly articulated, and we need to develop theories of change in context of these diverse perspectives. Our guiding future imaginaries must be informed by other academic fields, such as democratic theory and critical theory, and should be co-developed with social science scholars, legal scholars, civil rights and social justice activists, and artists, among others.
Neuro-symbolic is not enough, we need neuro-*semantic*Frank van Harmelen
Neuro-symbolic (NeSy) AI is on the rise. However, simply machine learning on just any symbolic structure is not sufficient to really harvest the gains of NeSy. These will only be gained when the symbolic structures have an actual semantics. I give an operational definition of semantics as “predictable inference”.
All of this illustrated with link prediction over knowledge graphs, but the argument is general.
Epistemic Interaction - tuning interfaces to provide information for AI supportAlan Dix
Paper presented at SYNERGY workshop at AVI 2024, Genoa, Italy. 3rd June 2024
https://alandix.com/academic/papers/synergy2024-epistemic/
As machine learning integrates deeper into human-computer interactions, the concept of epistemic interaction emerges, aiming to refine these interactions to enhance system adaptability. This approach encourages minor, intentional adjustments in user behaviour to enrich the data available for system learning. This paper introduces epistemic interaction within the context of human-system communication, illustrating how deliberate interaction design can improve system understanding and adaptation. Through concrete examples, we demonstrate the potential of epistemic interaction to significantly advance human-computer interaction by leveraging intuitive human communication strategies to inform system design and functionality, offering a novel pathway for enriching user-system engagements.
GDG Cloud Southlake #33: Boule & Rebala: Effective AppSec in SDLC using Deplo...James Anderson
Effective Application Security in Software Delivery lifecycle using Deployment Firewall and DBOM
The modern software delivery process (or the CI/CD process) includes many tools, distributed teams, open-source code, and cloud platforms. Constant focus on speed to release software to market, along with the traditional slow and manual security checks has caused gaps in continuous security as an important piece in the software supply chain. Today organizations feel more susceptible to external and internal cyber threats due to the vast attack surface in their applications supply chain and the lack of end-to-end governance and risk management.
The software team must secure its software delivery process to avoid vulnerability and security breaches. This needs to be achieved with existing tool chains and without extensive rework of the delivery processes. This talk will present strategies and techniques for providing visibility into the true risk of the existing vulnerabilities, preventing the introduction of security issues in the software, resolving vulnerabilities in production environments quickly, and capturing the deployment bill of materials (DBOM).
Speakers:
Bob Boule
Robert Boule is a technology enthusiast with PASSION for technology and making things work along with a knack for helping others understand how things work. He comes with around 20 years of solution engineering experience in application security, software continuous delivery, and SaaS platforms. He is known for his dynamic presentations in CI/CD and application security integrated in software delivery lifecycle.
Gopinath Rebala
Gopinath Rebala is the CTO of OpsMx, where he has overall responsibility for the machine learning and data processing architectures for Secure Software Delivery. Gopi also has a strong connection with our customers, leading design and architecture for strategic implementations. Gopi is a frequent speaker and well-known leader in continuous delivery and integrating security into software delivery.
Transcript: Selling digital books in 2024: Insights from industry leaders - T...BookNet Canada
The publishing industry has been selling digital audiobooks and ebooks for over a decade and has found its groove. What’s changed? What has stayed the same? Where do we go from here? Join a group of leading sales peers from across the industry for a conversation about the lessons learned since the popularization of digital books, best practices, digital book supply chain management, and more.
Link to video recording: https://bnctechforum.ca/sessions/selling-digital-books-in-2024-insights-from-industry-leaders/
Presented by BookNet Canada on May 28, 2024, with support from the Department of Canadian Heritage.
From Siloed Products to Connected Ecosystem: Building a Sustainable and Scala...
Tests that use dna from mother’s blood to
1. Manuela Amaya Cossio Medicine student 3rd semester Molecular biology Tests That Use DNA from Mother’s Blood to Determine Sex of Fetus Often Effective and Genetic Analysis of Amniotic Fluid Shows Promise for Monitoring Fetal Development
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4. Thistechniqueneedsthe DNA amplificationformakingbiggertheworkszoneitoffersitthe performance, duration, specificity, detectioncapability and fidelitytothemethod Withalltheapplicationsthe PCR has, thevariations of themethod has to look foranspecifictopic and makeit a betterofferforgettingtheproblem, they determine , increaseamplify, generate copies and impruvesensitivityforsome DNA fragments
5. Tests That Use DNA from Mother’s Blood to Determine Sex of Fetus Often Effective Science Daily (Aug. 9, 2011)
6. Tests That Use DNA from Mother’s Blood to Determine Sex of Fetus Often Effective Noninvasive prenatal determination of fetal sex could provide an important alternative to invasive cytogenetic determination, which is currently the gold standard for determining sex and single-gene disorders.
7. Tests That Use DNA from Mother’s Blood to Determine Sex of Fetus Often Effective Using cell-free fetal DNA which describes the test's ability to detect Y chromosome sequences within maternal samples, as well as the clinical validity of the test, as indicated by its ability to correctly identify fetal sex.
8. Tests That Use DNA from Mother’s Blood to Determine Sex of Fetus Often Effective Performance was high using maternal blood. DNA methodology and gestational age had the largest effects on test performance, with real-time quantitative polymerase chain reaction (RTQ-PCR) outperforming conventional PCR
9. Student observation lot of diseases have been diagnosticated latter on life's person , just because there is not technology for doing it, so here is a tool could help people to do it, preventing those identity, sexual, psychological, physical and family problems.
10. Genetic Analysis of Amniotic Fluid Shows Promise for Monitoring Fetal Development Science Daily (Aug. 9, 2011
11. Genetic Analysis of Amniotic Fluid Shows Promise for Monitoring Fetal Development Using a previously developed SNAP gene panel as proof of concept, investigators determined that 7 of the 21 genes assayed were expressed differently depending on fetal sex or gestational age. Results were obtained from amniotic fluid supernatant samples from fetuses between 15 to 20 weeks of gestation, when standard amniotic fluid testing is performed.
12. Genetic Analysis of Amniotic Fluid Shows Promise for Monitoring Fetal Development According to the investigators, further studies using this gene panel approach could elucidate the complex immune pathways involved in the maternal-fetal relationship.
13. Genetic Analysis of Amniotic Fluid Shows Promise for Monitoring Fetal Development Focused fetal gene expression analysis of target genes found in amniotic fluid using Standardized NanoArray PCR (SNAP) technology. And showed that This analysis could be used to monitor fetal development.
14. Student observation A fetus development involve lot of moments and each one needs the biggest attention because in any of them could occur a mistake, having the tool for follow this process can give parents the thrusts they need or the opportunity to give the baby a prudent treatment and prevent with it something worst for baby´s live
16. Medical utility Overthe time, technology has helphumansgettingtheirdreams and makethem true, todaywe can seeit and enjoyitwiththings as live, borntoday has becomeon a verycareposibility and baby´shealthmeansthemostimportantobjective.
17. Medical utility Medicine takesthosediscoveries and putthemonparentshandsgivingthem more options in case theyneedthemjustlookingforsomethingbetter. In this case thechniqueis use foranearlydiagnostic of sexual deseases, it can changes a complete life.
18. Medical utility Withthismethodparents can knowhowisgoingontheirsbabydevelopmentevenif he hasn´tborn, thedetection and earlytreatment of deformations, disseases, geneticdesorders and anyotherproblems can bediagnosticatedwithmotheramnioticliquid.
19. Bibliography MARTINEZ S. Lina maría. Biología molecular. 6 ed. Medellín: UPB facultad de medicina. 2011. 113-126. p. · Tests That Use DNA from Mother’s Blood to Determine Sex of Fetus Often Effective Science Daily (Aug. 9, 2011) de: http://www.sciencedaily.com/releases/2011/08/110809162000.htm · Genetic Analysis of Amniotic Fluid Shows Promise for Monitoring Fetal Development Science Daily (Aug. 9, 2011) de: http://www.sciencedaily.com/releases/2011/08/110808083812.htm