The presentation deals with a detailed study of soft gelatin capsules. this involves the production of soft gelatin capsule based on the importance of base adsorption factor and minim/gram factor. also quality control studies was also elaborated.
The presentation deals with a detailed study of soft gelatin capsules. this involves the production of soft gelatin capsule based on the importance of base adsorption factor and minim/gram factor. also quality control studies was also elaborated.
Methods of enhancing Dissolution and bioavailability of poorly soluble drugsRam Kanth
Greetings!
Good Day to all...
Topic: Methods of Enhancing Bioavailability
Several approaches discussed are
1. Micrnoization
2. Use of Surrfactants
3. Use of Salt forms
4. Alteration of pH of microenvironment
5. Use of metastable polymorphs
6. Solute-Solvent Complexation
7. Solvent Deposition
8. Selective Adsorption on Insoluble Carriers
9. Solid Solutions
10. Eutectic Mixtures
11. Solid Dispersions
12. Molecular Encapsulation with Cyclodextrins
Please do clarify for doubts if any....
Thank you all for watching this presentation.
The chapter deals with the preformulation studies that have to be considered while designing a dosage form and developing a formulation that is suitable for a patient. Here, physical and chemical properties of a drug substance are studied along with biopharmaceutical classification of drugs. Also a detailed study on the application of preformulation studies in different dosage forms are also studied.
These presentation describes the rules and regulations for the manufacture of drugs and grant of license. Loan License and Repacking License is also described. These presentation is the part of series Drugs & Cosmetics Act.
Liquid oral topic in Industrial Pharmacy contains many topics like solution, elixirs, syrups, emulsion, and suspension. This topic includes general introduction, types, formulation, components, uses, and Quality control tests. These are also beneficial in other subjects like Pharmaceutics.
Potential of Seabuckthorn (Hippophae L.) - A Multipurpose Under-utilized Crop...apaari
Potential of Seabuckthorn (Hippophae L.) - A Multipurpose Under-utilized Crop of Dry Temperate Himalayas by Virendra Singh, HPKV, India - Regional Expert Consultation on Underutilized Crops for Food and Nutritional Security in Asia and the Pacific November 13-15, 2017, Bangkok
ANTIOXIDANT ACTIVITY AND HEPATOPROTECTIVE EFFECT OF POMEGRANATE PEEL AND WHEY...Anurag Raghuvanshi
The antioxidant activity of pomegranate peel powder (PPP) and whey powder (WP) was evaluated, their hepatoprotective effect of each alone or in combination (PPWP) at equal levels was also evaluated in Wistar rats against carbon tetrachloride (CCL4) induced liver injury.
The hepatoprotective activity was assessed using various biochemical parameters and histopathological studies.
Methods of enhancing Dissolution and bioavailability of poorly soluble drugsRam Kanth
Greetings!
Good Day to all...
Topic: Methods of Enhancing Bioavailability
Several approaches discussed are
1. Micrnoization
2. Use of Surrfactants
3. Use of Salt forms
4. Alteration of pH of microenvironment
5. Use of metastable polymorphs
6. Solute-Solvent Complexation
7. Solvent Deposition
8. Selective Adsorption on Insoluble Carriers
9. Solid Solutions
10. Eutectic Mixtures
11. Solid Dispersions
12. Molecular Encapsulation with Cyclodextrins
Please do clarify for doubts if any....
Thank you all for watching this presentation.
The chapter deals with the preformulation studies that have to be considered while designing a dosage form and developing a formulation that is suitable for a patient. Here, physical and chemical properties of a drug substance are studied along with biopharmaceutical classification of drugs. Also a detailed study on the application of preformulation studies in different dosage forms are also studied.
These presentation describes the rules and regulations for the manufacture of drugs and grant of license. Loan License and Repacking License is also described. These presentation is the part of series Drugs & Cosmetics Act.
Liquid oral topic in Industrial Pharmacy contains many topics like solution, elixirs, syrups, emulsion, and suspension. This topic includes general introduction, types, formulation, components, uses, and Quality control tests. These are also beneficial in other subjects like Pharmaceutics.
Potential of Seabuckthorn (Hippophae L.) - A Multipurpose Under-utilized Crop...apaari
Potential of Seabuckthorn (Hippophae L.) - A Multipurpose Under-utilized Crop of Dry Temperate Himalayas by Virendra Singh, HPKV, India - Regional Expert Consultation on Underutilized Crops for Food and Nutritional Security in Asia and the Pacific November 13-15, 2017, Bangkok
ANTIOXIDANT ACTIVITY AND HEPATOPROTECTIVE EFFECT OF POMEGRANATE PEEL AND WHEY...Anurag Raghuvanshi
The antioxidant activity of pomegranate peel powder (PPP) and whey powder (WP) was evaluated, their hepatoprotective effect of each alone or in combination (PPWP) at equal levels was also evaluated in Wistar rats against carbon tetrachloride (CCL4) induced liver injury.
The hepatoprotective activity was assessed using various biochemical parameters and histopathological studies.
Spirulina Filipina Foundation is a new concept of livelihood generation combined with humanitarian activities. SFF is a non profit organisation.
Mission
To encourage VOLUNTEERS to join the organization and provide them additional income for their work while distributing the profits and donations of the Fondation through feeding programs and other usefull activities in favor of less fortunate people and eldery community.
Company Overview
SFF is the operational non-profit arm of DLA NATURALS inc. and is active in providing system to generate income for the Volunteers joining the organization while distributing its income through feeding programs and other usuefull actions in favor of less fortunate people.
Spirulina is a microscopic form of bacteria, growing naturally for centuries in alkaline waters. They are corkscrew-shaped multicellular filaments--thus the name Spirulina.
Check the links below
http://www.spirulinafilipina.com/
http://www.spirulinafilipina.com/products/
Its minerals and vitamins are naturally bio-chelated, meaning they are wrapped in amino-acids for excellent assimilation by the body. It contains over 100 synergistic nutrients and is nature's richest and most complete single source of total organic nutrition.
Spirulina is a completely natural, powerful, wide-ranging and diverse group of nutrients which provides the body with proper and balanced nutrition. It is also a superior approach to nutrition therapy to prevent today’s prevalent ailments and diseases.
Spirulina health benefits based on nutrition therapy:
1. CELLULAR Repair
2. CELLULAR Protection
3. CELLULAR Nourishment
4. BOOSTS the immune system
5. PROTECTS and REPAIRS CELLS from DAMAGE
due to FREE RADICALS.
6. Improves internal-external wound healing
7. Helps build healthy Lactobacillus
8. ELEVATES ENERGY LEVELS
9. Anti-Radiation
10. Eliminates Malnutrition
11. Helps to correct sugar levels
12. Neuro-protective (Brain)
13. Cardio-protective (Heart) 14. Hepatoprotective (Liver)
15. Renal-Protective (Kidney)
16. Balances Blood Chemistry
17. Strengthens circulation
18. Strengthens nerves
19. Anti-AUTOIMMUNE DISEASES
20. PREVENTS and FIGHTS BODY ILLNESSES
21. Superior Anti-inflammatory
22. Nerve and Muscle relaxant
23. Food for the Eyesight
24. Helps your body produce it own Glutathione
25. Balances body’s hormonal secretions
26. Food for all ages!
Spirulina is endorsed by such respectable and highly-reputed organizations such as:
1967: “The International Conference on Applied Microbiology” has announced that, “Spirulina must be considered as an important future food source.”
1974: UN (United Nations)announced in the World Food Conference that Spirulina is, “The most ideal food for mankind.”
1974: FAO (Food and Agriculture Organization) introduced Spirulina as, “The best food for tomorrow.”
1981: FDA (Food and Drug Administration) of USA has certified that Spirulina is, “The healthy and safety product free from side effects.”
1983: IFE (International Food Exposition) held in East Germany awarded the prize: “The Best Natural Food” to Spirulina.
1992: WHO (World Health Organization) introduced Spirulina as, “The healthy product in 21st Century” and has been declared by NASA as, “One of the most nutritious foods on earth.” One (1) gram ( 2 capsules of 500 milligrams) of pure Spirulina is equivalent to one (1) kilo of assorted leafy vegetables.
2005: In the 60th Session of the United Nations General Assembly, it was declared that Spirulina be promoted as the solution for malnutrition.
This presentation was made in Sept 2010 at Manila during the Poultry show. Target audience were nutritionists , poultry consultants and feed manufacturers
Comparative Studies of the Aqueous Extracts of OcimumGratissimum, Aloe Vera, ...IOSR Journals
The current orthodox treatment modalities for diabetic mellitus have many setbacks including undesirable side effects and the high cost of long term treatment. The aim of this study was to determine the anti-diabetic effectsand compare some biochemical parameters of four plants; Ocimumgratissimum (OG),Aloe vera (AV), Brassica oleracea(BO) and Ipomoea batatas(IB) on alloxan induced diabetic rats. The preliminary phytochemical screening reveals the presence ofalkaloid, tannin, cardiac glycoside, resin and steroids in all four plants. Diabetic was induced by interperitonial injection of alloxan monohydrate while treatment was done for 21 days. Diabetic rats had significant increased (P˂0.05)cholesterol, triglyceride (TG), Low Density Lipoprotein (LDL) and artherogenic index (AI). Treatment of experimental rats with 150 mg/kg bw. of aqueous extractsof plants significantly decrease (P˂0.05) the levels of cholesterol and LDL in OG and BO treated groups when compare with the control. Computed artherogenic index was significantly reduced (P˂0.05) in AV treated group when compared to the control. Aqueous extracts also significantly (P˂0.05) alter serum concentrations of alkaline phosphatase (ALP), alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in a similar manner with metformin treated group. Result showed that decrease in plasma glucose was in the order IB˃OG˃BO˃AV. All plant extracts possess antidiabetic, anti-hyperlipidemic effects and were able to ameliorate the weight loss observed in diabetic rats
Presentation during the Bureau of Agricultural Research (BAR) Seminar Series on June 22, 2017 at RDMIC Bldg., cor. Visayas Ave., Elliptical Rd., Diliman, Quezon City
Ecuadorian Rainforest, LLC is a supplier of all natural fruit, herb, marine, spice and vegetable ingredients.
This presentation highlights the health benefits of ingredients found in Latin America.
For more information, a sample or pricing please use the contact form or email us at info@intotherainforest.com
A phytosome is a complex of a natural active ingredient and a phospholipid - mostly lecithin. It is claimed that phytosome increases absorption of "conventional herbal extracts" or isolated active principles both topically as well as orally.
FENFURO™ is a proprietary product derived from Fenugreek seeds (Trigonella Foenum Graecum) by an innovative process. It is a group of furostanolic saponins that help to maintain healthy blood glucose levels. FENFURO contains a rich variety of saponins and flavonoids. All of these substances are known to play valuable role in maintaining a stable Glucose levels.
Fenfuro is supported by 7 international patents and has also been clinically evaluated on 454 diabetic patients. The clinical studies have been published in well-known international journals and have won awards in many international conferences.
It is an Over the Counter (OTC) product and has been approved by FSSAI.
a review of prebiotic product used in human and animal nutritionSeidu Oluwaseunla
A nondigestible food ingredient that beneficially affects the host by selectively stimulating the growth and/or activity of one or a limited number of bacteria in the colon, and thus improves host health (Gibson and Roberfroid. 1995)
Somatropin human growth hormone (HGH) dosage & administrationJS Biology
Somatropin human growth hormone (HGH) dosage & administration schedule should be individualized for each patient. Therapy should not be continued if epiphyseal fusion has occurred. Response to growth hormone therapy tends to decrease with time. However, failure to increase growth rate, particularly during the first year of therapy, should prompt close assessment of compliance and evaluation of other causes of growth failure such as hypothyroidism, under-nutrition, and advanced bone age. Growth hormone-deficient pediatric patients --The recommended weekly dosage is 0.18 mg/kg (0.54 IU/kg) of body weight. The maximal replacement weekly dosage is 0.3 mg/kg (0.90 IU/kg) of body weight. It should be divided into equal doses given either on 3 alternate days, 6 times per week, or daily. The subcutaneous route of administration is preferable; intramuscular injection is also acceptable. The dosage and administration schedule for Somatropin should be individualized for each patient.
Dietary Intervention with Yoghurt, Synbiotic Yogurt or Traditional Fermented ...Mostafa Gouda
Dietary Intervention with Yoghurt, Synbiotic
Yogurt or Traditional Fermented Sobya:
Bio-Potency among Male Adolescents Using
Five Bio-Markers of Relevance to Colonic
Metabolic Activities
Pushing the limits of ePRTC: 100ns holdover for 100 daysAdtran
At WSTS 2024, Alon Stern explored the topic of parametric holdover and explained how recent research findings can be implemented in real-world PNT networks to achieve 100 nanoseconds of accuracy for up to 100 days.
The Art of the Pitch: WordPress Relationships and SalesLaura Byrne
Clients don’t know what they don’t know. What web solutions are right for them? How does WordPress come into the picture? How do you make sure you understand scope and timeline? What do you do if sometime changes?
All these questions and more will be explored as we talk about matching clients’ needs with what your agency offers without pulling teeth or pulling your hair out. Practical tips, and strategies for successful relationship building that leads to closing the deal.
GDG Cloud Southlake #33: Boule & Rebala: Effective AppSec in SDLC using Deplo...James Anderson
Effective Application Security in Software Delivery lifecycle using Deployment Firewall and DBOM
The modern software delivery process (or the CI/CD process) includes many tools, distributed teams, open-source code, and cloud platforms. Constant focus on speed to release software to market, along with the traditional slow and manual security checks has caused gaps in continuous security as an important piece in the software supply chain. Today organizations feel more susceptible to external and internal cyber threats due to the vast attack surface in their applications supply chain and the lack of end-to-end governance and risk management.
The software team must secure its software delivery process to avoid vulnerability and security breaches. This needs to be achieved with existing tool chains and without extensive rework of the delivery processes. This talk will present strategies and techniques for providing visibility into the true risk of the existing vulnerabilities, preventing the introduction of security issues in the software, resolving vulnerabilities in production environments quickly, and capturing the deployment bill of materials (DBOM).
Speakers:
Bob Boule
Robert Boule is a technology enthusiast with PASSION for technology and making things work along with a knack for helping others understand how things work. He comes with around 20 years of solution engineering experience in application security, software continuous delivery, and SaaS platforms. He is known for his dynamic presentations in CI/CD and application security integrated in software delivery lifecycle.
Gopinath Rebala
Gopinath Rebala is the CTO of OpsMx, where he has overall responsibility for the machine learning and data processing architectures for Secure Software Delivery. Gopi also has a strong connection with our customers, leading design and architecture for strategic implementations. Gopi is a frequent speaker and well-known leader in continuous delivery and integrating security into software delivery.
Unlocking Productivity: Leveraging the Potential of Copilot in Microsoft 365, a presentation by Christoforos Vlachos, Senior Solutions Manager – Modern Workplace, Uni Systems
Communications Mining Series - Zero to Hero - Session 1DianaGray10
This session provides introduction to UiPath Communication Mining, importance and platform overview. You will acquire a good understand of the phases in Communication Mining as we go over the platform with you. Topics covered:
• Communication Mining Overview
• Why is it important?
• How can it help today’s business and the benefits
• Phases in Communication Mining
• Demo on Platform overview
• Q/A
Enchancing adoption of Open Source Libraries. A case study on Albumentations.AIVladimir Iglovikov, Ph.D.
Presented by Vladimir Iglovikov:
- https://www.linkedin.com/in/iglovikov/
- https://x.com/viglovikov
- https://www.instagram.com/ternaus/
This presentation delves into the journey of Albumentations.ai, a highly successful open-source library for data augmentation.
Created out of a necessity for superior performance in Kaggle competitions, Albumentations has grown to become a widely used tool among data scientists and machine learning practitioners.
This case study covers various aspects, including:
People: The contributors and community that have supported Albumentations.
Metrics: The success indicators such as downloads, daily active users, GitHub stars, and financial contributions.
Challenges: The hurdles in monetizing open-source projects and measuring user engagement.
Development Practices: Best practices for creating, maintaining, and scaling open-source libraries, including code hygiene, CI/CD, and fast iteration.
Community Building: Strategies for making adoption easy, iterating quickly, and fostering a vibrant, engaged community.
Marketing: Both online and offline marketing tactics, focusing on real, impactful interactions and collaborations.
Mental Health: Maintaining balance and not feeling pressured by user demands.
Key insights include the importance of automation, making the adoption process seamless, and leveraging offline interactions for marketing. The presentation also emphasizes the need for continuous small improvements and building a friendly, inclusive community that contributes to the project's growth.
Vladimir Iglovikov brings his extensive experience as a Kaggle Grandmaster, ex-Staff ML Engineer at Lyft, sharing valuable lessons and practical advice for anyone looking to enhance the adoption of their open-source projects.
Explore more about Albumentations and join the community at:
GitHub: https://github.com/albumentations-team/albumentations
Website: https://albumentations.ai/
LinkedIn: https://www.linkedin.com/company/100504475
Twitter: https://x.com/albumentations
Why You Should Replace Windows 11 with Nitrux Linux 3.5.0 for enhanced perfor...SOFTTECHHUB
The choice of an operating system plays a pivotal role in shaping our computing experience. For decades, Microsoft's Windows has dominated the market, offering a familiar and widely adopted platform for personal and professional use. However, as technological advancements continue to push the boundaries of innovation, alternative operating systems have emerged, challenging the status quo and offering users a fresh perspective on computing.
One such alternative that has garnered significant attention and acclaim is Nitrux Linux 3.5.0, a sleek, powerful, and user-friendly Linux distribution that promises to redefine the way we interact with our devices. With its focus on performance, security, and customization, Nitrux Linux presents a compelling case for those seeking to break free from the constraints of proprietary software and embrace the freedom and flexibility of open-source computing.
Generative AI Deep Dive: Advancing from Proof of Concept to ProductionAggregage
Join Maher Hanafi, VP of Engineering at Betterworks, in this new session where he'll share a practical framework to transform Gen AI prototypes into impactful products! He'll delve into the complexities of data collection and management, model selection and optimization, and ensuring security, scalability, and responsible use.
Climate Impact of Software Testing at Nordic Testing DaysKari Kakkonen
My slides at Nordic Testing Days 6.6.2024
Climate impact / sustainability of software testing discussed on the talk. ICT and testing must carry their part of global responsibility to help with the climat warming. We can minimize the carbon footprint but we can also have a carbon handprint, a positive impact on the climate. Quality characteristics can be added with sustainability, and then measured continuously. Test environments can be used less, and in smaller scale and on demand. Test techniques can be used in optimizing or minimizing number of tests. Test automation can be used to speed up testing.
Epistemic Interaction - tuning interfaces to provide information for AI supportAlan Dix
Paper presented at SYNERGY workshop at AVI 2024, Genoa, Italy. 3rd June 2024
https://alandix.com/academic/papers/synergy2024-epistemic/
As machine learning integrates deeper into human-computer interactions, the concept of epistemic interaction emerges, aiming to refine these interactions to enhance system adaptability. This approach encourages minor, intentional adjustments in user behaviour to enrich the data available for system learning. This paper introduces epistemic interaction within the context of human-system communication, illustrating how deliberate interaction design can improve system understanding and adaptation. Through concrete examples, we demonstrate the potential of epistemic interaction to significantly advance human-computer interaction by leveraging intuitive human communication strategies to inform system design and functionality, offering a novel pathway for enriching user-system engagements.
Encryption in Microsoft 365 - ExpertsLive Netherlands 2024Albert Hoitingh
In this session I delve into the encryption technology used in Microsoft 365 and Microsoft Purview. Including the concepts of Customer Key and Double Key Encryption.
GridMate - End to end testing is a critical piece to ensure quality and avoid...ThomasParaiso2
End to end testing is a critical piece to ensure quality and avoid regressions. In this session, we share our journey building an E2E testing pipeline for GridMate components (LWC and Aura) using Cypress, JSForce, FakerJS…
Goodbye Windows 11: Make Way for Nitrux Linux 3.5.0!SOFTTECHHUB
As the digital landscape continually evolves, operating systems play a critical role in shaping user experiences and productivity. The launch of Nitrux Linux 3.5.0 marks a significant milestone, offering a robust alternative to traditional systems such as Windows 11. This article delves into the essence of Nitrux Linux 3.5.0, exploring its unique features, advantages, and how it stands as a compelling choice for both casual users and tech enthusiasts.
In the rapidly evolving landscape of technologies, XML continues to play a vital role in structuring, storing, and transporting data across diverse systems. The recent advancements in artificial intelligence (AI) present new methodologies for enhancing XML development workflows, introducing efficiency, automation, and intelligent capabilities. This presentation will outline the scope and perspective of utilizing AI in XML development. The potential benefits and the possible pitfalls will be highlighted, providing a balanced view of the subject.
We will explore the capabilities of AI in understanding XML markup languages and autonomously creating structured XML content. Additionally, we will examine the capacity of AI to enrich plain text with appropriate XML markup. Practical examples and methodological guidelines will be provided to elucidate how AI can be effectively prompted to interpret and generate accurate XML markup.
Further emphasis will be placed on the role of AI in developing XSLT, or schemas such as XSD and Schematron. We will address the techniques and strategies adopted to create prompts for generating code, explaining code, or refactoring the code, and the results achieved.
The discussion will extend to how AI can be used to transform XML content. In particular, the focus will be on the use of AI XPath extension functions in XSLT, Schematron, Schematron Quick Fixes, or for XML content refactoring.
The presentation aims to deliver a comprehensive overview of AI usage in XML development, providing attendees with the necessary knowledge to make informed decisions. Whether you’re at the early stages of adopting AI or considering integrating it in advanced XML development, this presentation will cover all levels of expertise.
By highlighting the potential advantages and challenges of integrating AI with XML development tools and languages, the presentation seeks to inspire thoughtful conversation around the future of XML development. We’ll not only delve into the technical aspects of AI-powered XML development but also discuss practical implications and possible future directions.
2. INNOVATOR COMPANY
Indena Phytosome® U.S. Patent # 4,764,508
world's leading company in the identification,
development and production of active principles
derived from plants, for use in pharmaceutical, health-
food and personal care industy.
6. Siliphos® Bioavailable silybin
Plasma levels of total silybin after oral Silipide® and silybin in rats, where Silipide® (200
mg/kg as silybin) and silybin (200 mg/kg) were administered by gavage as aqueous
suspensions to 6 male rats.
7. Ginkgoselect® Phytosome vs Ginkgo biloba
extract
Fifteen healthy volunteers two groups and administered
respectively 160 mg of free formulation of GBE and
160 mg of Ginkgoselect® Phytosome®
8. Meriva® vs Curcumin
In comparative study in humans the overall curcuminoid absorption was about 29-fold higher.
12. Conclusion
All that man needs for health and healing has
been provided by God in nature, the challenge of
science is to find it.
Novel drug delivery systems of herbal drugs have a
potential future for enhancing the activity and
overcoming problems associated with plant
medicines.
