Akoya announced the launch of PhenoCode™ Signature Panels for high-throughput spatial biomarker discovery and validation on the PhenoImager® platforms, providing the flexibility to keep pace with the dynamic combination therapy landscape. Additionally, Akoya has brought new datasets of spatial imaging of complementary RNA and protein biomarkers on the PhenoCycler®-Fusion system, which reveal insights into tumor biology and immunotherapyresponse..https://www.gaiascience.com.sg/branddetails/akoya-biosciences

1. Recently Akoya announced the launch of PhenoCode™ Signature Panels for high-throughput spatial
biomarker discovery and validation on the PhenoImager® platforms, providing the flexibility to keep
pace with the dynamic combination therapy landscape.
Additionally, Akoya has brought new datasets of spatial imaging of complementary RNA and protein
biomarkers on the PhenoCycler®-Fusion system, which reveal insights into tumor biology and
immunotherapy response.
Rapid whole-slide spatial analysis of FFPE tissues
with true multiomic panels enables the discovery of
key cellular niches
These multiomic data show the value of using protein
imaging data for cell typing and clearer differentiation
and overlaying RNA imaging data to understand the
functional state of those same cells of interest.
RNA chemistry is combined with protein chemistry on
the PhenoCycler-Fusion (PCF) imaging system, users
can obtain more exquisite cell typing while
understanding specific functional states of each cell.
Multiomic Spatial Phenotyping of Immunotherapy
Responses in Head and Neck Cancer
This poster demonstrates how multiomic spatial
phenotyping was used to produce a uniquely
comprehensive analysis of the patient's tumor
microenvironment (TME) and how it explains partial
response to immune checkpoint inhibitor therapy.
Compared to traditional H&E staining, using the
powerful multiomic (RNA + protein) assay on the
same tissue of serial sections, researchers can see the
dynamic interplay of cells and their functional states
in the heterogeneous TME.
New Product Introduction
Empower Your
Spatial Multiomics
Research
Posters: Spatial Imaging of Complementary RNA and Protein Biomarkers
PhenoCode Signature panels blend the sensitivity of the Opal-
TSA detection system with features of Akoya's proprietary
barcode-based antibody labeling chemistry on the PhenoImager
platforms. It allows for the easy integration of a novel checkpoint
or immune cell marker; these panels offer 3-fold faster assay
development and optimization times compared to other custom
6-plex panels.
Jumpstart Spatial Signatures
View more posters and recordings of the talks at AGBT 2023
View more posters and recordings of the talks at AGBT 2023