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Jim McVeigh
Director
Public Health Institute
Anabolic steroids: a global public
health perspective
Surveillance data from NSPs (1991 - 2016);
UK survey data (2013- 2016) 1549 IPED users:
demographics, drug use histories, health profiles, risk
behaviour and motivations for use;
HIV, hepatitis B and hepatitis C prevalence data from PHE
surveillance system of people who inject drugs (from1992 -
2016) and two bespoke IPED injector surveys;
Global Drug Survey 2015
Datasources
Reproduced from www.ifbb.ru
News U.S. Sport TV&Showbiz Australia Femail Health Science Money Video Travel Fashion Finder
adlines News World News Arts Headlines France Pictures Most read Wires Discounts Login
Mug shot: Moat was well known to
Northumbria Police, and he
believed they victimised him
Control freak and his reign
of terror: Pumped full of
steroids, sword-wielding
club bouncer Moat thought
he was irresistible
By PAUL SIMS FOR MAILONLINE
UPDATED: 09:41, 5 July 2010
Raoul Moat is an
unpredictable control freak
with a violent temper who
snaps without warning, say
friends and family.
The 6ft-plus ex-nightclub
bouncer, who is addicted to
steroids and anti-
depressants, is so paranoid
that he wired his house up
with CCTV cameras and
microphones, neighbours
said.
He was caught by police
carrying a serrated steel
knuckle duster and a
terrifying 5ft long Samurai
sword and has links to
Newcastle gangsters.
But Samantha Stobbart was
almost blind to his serious flaws, said her half sister, Kelly, 27.
'Sam thought he was the bee's knees,' she said yesterday.
'Her problem was that she could not see above Raoul's chest.
View comments
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PICTURE EXCLUSIVE:
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FIRST LOOK: A yoga-
loving health inspector,
a handsome architect
and the oldest baking
contestant yet: Meet the
eclectic Bake Off stars
of Channel 4 relaunch
I wanted to hate Bake
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have to eat my words:
SARAH RAINEY's first
review of Channel 4's
Great British Bake Off
Lindsay Lohan flaunts
her cleavage in a
plunging red swimsuit...
and relaxes with a male
In reality…
Anabolic steroids definition
Mimic the effects of testosterone
Testosterone - anabolic & androgenic
Anabolic - growth & development of tissue
Androgenic - secondary male sexual
characteristics
Testosterone production
PANIC!
PANIC!
Berthold 1849
Testosterone
0
0.2
0.4
0.6
0.8
1
1.2
last year
Ever
YP last year
“Have you ever taken anabolic steroids
(steroids) (not prescribed by a doctor) even
if it was a long time ago?”
Anabolic steroid use in last year/ever
Adults ever 356,000 (302,000 – 411,000)
Adults last year 61,000 (38,000 – 83,000)
YP last year 23,000 (5,000 – 40,000)
‘All’ & ‘new’ clients attending agency based NSPs in
Liverpool City Region (1991 to 2011)
0
500
1,000
1,500
2,000
2,500
3,000
1991
1992
1993
1994
1995
1996
1997
1998
1999
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
2010
2011
Number
of
Clients
Year of Presentation/Attendance
New AS injecting clients
New other injecting clients
AS injecting clients
Other injecting clients
Middlesbrough 67%
Kirklees 60%
Sheffield 62%
Newcastle 52%
Sunderland 60%
Bradford 41%
Halton 86%
Liverpool 83%
Sefton 43%
St Helens 34%
Warrington 86%
Wirral 77%
Manchester 60%
Bolton 52%
NSP clients using anabolic steroids in Northern England
(Kimergard & McVeigh, 2014)
Anabolic steroid users accessing NSPs in
Cheshire and Merseyside, UK (1995 and 2015)
(McVeigh & Begley, 2017)
Anabolic steroid users attending NSPs in
Liverpool City Region (1995 and 2015)
1995 2015
Number of anabolic steroid NSP clients 553 2446
Proportion of NSP clients 17% 55%
Syringes provided to steroid users 14,293 139,956
Mean syringes per steroid user 26 57
(McVeigh & Begley, 2017)
Harms associated with
anabolic steroid use
Adverse effects on several organ/systems in particular:
Cardiovascular effects
Haematologic effects
Psychiatric and neuropsychologic effects
Hormonal and metabolic effects
Variety of less frequent effects on various other bodily tissues.
Pope et al, 2013
Adverse Health Consequences of Performance Enhancing Drugs
An Endocrine Society Scientific Statement
Bilateral deltoid abscesses pre-operative clinical appearance
Marquis & Maffulli, 2006
Marquis & Maffulli, 2006
Intra-operative drainage
2010/11 2012/13
Anti-HIV Prevalence 1.5% (400) 2.0% (249)
Anti-HBc Prevalence 8.7% (400) 2.8% (249)
Anti-HCV Prevalence 5.4% (400) 3.6% (249)
Level of sharing (direct & indirect) 8.9% (392) 13% (243)
Hepatitis B vaccine uptake 24% (375) 40% (246)
Symptom of injection site infection 6.9% (389) 16% (238)
Ever been in prison 17% (377) 24% (247)
Unlinked Anonymous Monitoring Survey of People Who Inject image
and performance enhancing drugs
Hope, McVeigh et al, 2014
22
From Glass R et al Secondary distribution of injecting equipment obtained from needle and syringe programmes
by people injecting image and performance enhancing drugs: England & Wales, 2012-15.
One in three of people using IPEDs
who use NSP distribute equipment
to others
Mid-point:
160 participants 1,040 others
Estimated extend of secondary distribution
There were 564 participants in the sample.
160 collected for others.
Minimum:
160 participants 667 others
23
Range of
users
which may
not be
engaging
with NSP
from our
sample
Glass R et al Secondary distribution of injecting equipment obtained from needle and syringe programmes by
people injecting image and performance enhancing drugs: England & Wales, 2012-15.
24
14%
86%
Ever injected a
psychoactive drug
Yes
No 46%
54%
Injected psychoactive drugs
during last year
Yes
No
Hope et al. Drug and Alcohol Dependence 2017;179 :83-86
Injection of psychoactive drugs
Prevalence of antibodies to hepatitis C
Overall one in twenty had antibodies
25
1.4%
39%
14%
0% 25% 50% 75% 100%
Never injected a psychoactive drug
Recently (in preceding 12 months)
injected a psychoactive
Previously injected a psychoactive
Hope et al. Drug and Alcohol Dependence 2017;179 :83-86
Awareness of having had hepatitis C
26
Hope et al. Drug and Alcohol Dependence 2017;’, 179 :83-86
0 5 10 15 20
Never injected a psychoactive drug
Recently (in preceding 12 months)
injected a psychoactive
Previously injected a psychoactive
Aware Unaware
Global phenomenon
993 male
anabolic
steroid users
96
250
525
104
Other 17
Global Drug Survey 2015 (89,509 responses)
Zahnow et al (2017)
Region of residence: AAS users as proportion of
GDS participants
Characteristics Total males Ever
used
% of total
males ever
used
Used in the
last 12
months
% of total male
used in last 12
months
Region
Europe 47,424 525 (1.10) 158 (0.33)
North America 3,038 96 (3.06) 27 (0.86)
South Americas 3,133 250 (7.39) 84 (2.48)
Oceania 4,080 104 (2.49) 38 (0.91)
Other 537 17 (3.07) 8 (1.44)
Total 58,212 993 (1.68) 315 (0.53)
Zahnow et al (2017)
Global Drug Survey – 993 steroid users
Drug Used in last 12
months
Lifetime use
Cannabis 63.1 87.8
Other drugs * 44.6 71.4
Ecstasy 41.8 61.3
Cocaine 38.7 61.3
Amphetamines 20.6 49.1
LSD 18.1 41.1
Benzodiazepines 28.2 34.8
NPS 14.0 31.0
Opiates 15.3 30.0
* Including magic mushrooms, poppers, nitrous, ketamine and GHB
Zahnow et al (2017)
Hope, V. D., McVeigh, J., Smith, J., Glass, R., Njoroge, J., Tanner, C., . . . Desai, M. (2017). Low levels of hepatitis C diagnosis and
testing uptake among people who inject image and performance enhancing drugs in England and Wales, 2012-15. Drug and Alcohol
Dependence, 179, 83-86.
McVeigh, J., & Begley, E. (2017). Anabolic steroids in the UK: an increasing issue for public health. Drugs: Education, Prevention and
Policy, 24.:3, 278-285
Hope, V. D., McVeigh, J., Marongiu, A., Evans-Brown, M., Smith, J., Kimergard, A., . . . Bellis, M. A. (2013). Prevalence of, and risk factors
for, HIV, hepatitis B and C infections among men who inject image and performance enhancing drugs: a cross-sectional study. BMJ
OPEN, 3(9), 11
McVeigh, J., Beynon, C., & Bellis, M. A. (2003). New challenges for agency based syringe exchange schemes: Analysis of 11 years of
data (1991-2001) in Merseyside and Cheshire, United Kingdom. International Journal of Drug Policy, 14(5-6), 399-405.
Zahnow, R., McVeigh, J., Ferris, J., & Winstock, A. (2017). Adverse effects, health service engagement, and service satisfaction among
anabolic androgenic steroid users. Contemporary Drug Problems 44(1):69-83 01
Hope, V. D., Harris, R., McVeigh, J., Cullen, K. J., Smith, J., Parry, J. V., . . . Ncube, F. (2016). Risk of HIV and Hepatitis B and C Over
Time Among Men Who Inject Image and Performance Enhancing Drugs in England and Wales: Results From Cross-Sectional Prevalence
Surveys, 1992-2013. JAIDS, 71(3), 331-337
Hope, V. D., McVeigh, J., Marongiu, A., Evans-Brown, M., Smith, J., Kimergard, A., . . . Ncube, F. (2015). Injection site infections and
injuries in men who inject image- and performance-enhancing drugs: prevalence, risks factors, and healthcare seeking. Epidemiology and
Infection, 143(1), 132-140.
McVeigh, J., bates, G., & chandler, M. (2015). Steroids and Image Enhancing Drugs 2014 Survey Results. http://www.cph.org.uk/wp-
content/uploads/2015/07/SIEDs-report-GB-JL-10-7-15-Final.pdf
Bates, G., & McVeigh, J. (2016). Image and Performance Enhancing Drugs 2015 Survey Results. Liverpool: Liverpool John Moores
University. http://www.cph.org.uk/wp-content/uploads/2016/07/IPEDs-2015-survey_final1.pdf
Kimergard, A., & McVeigh, J. (2014). Environments, risk and health harms: a qualitative investigation into the illicit use of anabolic steroids
among people using harm reduction services in the UK. BMJ Open, 4(6),
References
Jim McVeigh
Director
Public Health Institute
Liverpool John Moores University
0151 231 4512
j.mcveigh@ljmu.ac.uk

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Pharmacology pppdgsi u hb bh uidhhd hi ihbeh

  • 1. Jim McVeigh Director Public Health Institute Anabolic steroids: a global public health perspective
  • 2. Surveillance data from NSPs (1991 - 2016); UK survey data (2013- 2016) 1549 IPED users: demographics, drug use histories, health profiles, risk behaviour and motivations for use; HIV, hepatitis B and hepatitis C prevalence data from PHE surveillance system of people who inject drugs (from1992 - 2016) and two bespoke IPED injector surveys; Global Drug Survey 2015 Datasources
  • 3.
  • 5. News U.S. Sport TV&Showbiz Australia Femail Health Science Money Video Travel Fashion Finder adlines News World News Arts Headlines France Pictures Most read Wires Discounts Login Mug shot: Moat was well known to Northumbria Police, and he believed they victimised him Control freak and his reign of terror: Pumped full of steroids, sword-wielding club bouncer Moat thought he was irresistible By PAUL SIMS FOR MAILONLINE UPDATED: 09:41, 5 July 2010 Raoul Moat is an unpredictable control freak with a violent temper who snaps without warning, say friends and family. The 6ft-plus ex-nightclub bouncer, who is addicted to steroids and anti- depressants, is so paranoid that he wired his house up with CCTV cameras and microphones, neighbours said. He was caught by police carrying a serrated steel knuckle duster and a terrifying 5ft long Samurai sword and has links to Newcastle gangsters. But Samantha Stobbart was almost blind to his serious flaws, said her half sister, Kelly, 27. 'Sam thought he was the bee's knees,' she said yesterday. 'Her problem was that she could not see above Raoul's chest. View comments Site Web Enter your search Like Daily Mail Follow @dailymailuk Follow Daily Mail +1 Daily Mail DON'T MISS 'If you value your life, keep the f*** out of Islam': Loose Women star Saira Khan reports death threat to police after abusive comments on bikini picture Braless Demi Rose Mawby sets pulses racing as she displays her eye-popping assets and sensational curves in a plunging maroon dress for sizzling shoot PICTURE EXCLUSIVE: Pregnant Ferne McCann goes make-up free as she hides her blossoming bump in a sporty sweatshirt following gym session Blac Chyna flaunts her assets in a feathery semi-sheer micro dress for night out with busty pal Amber Rose... who looks unrecognisable in a long dark wig FIRST LOOK: A yoga- loving health inspector, a handsome architect and the oldest baking contestant yet: Meet the eclectic Bake Off stars of Channel 4 relaunch I wanted to hate Bake Off after Mary... but I have to eat my words: SARAH RAINEY's first review of Channel 4's Great British Bake Off Lindsay Lohan flaunts her cleavage in a plunging red swimsuit... and relaxes with a male
  • 6.
  • 8. Anabolic steroids definition Mimic the effects of testosterone Testosterone - anabolic & androgenic Anabolic - growth & development of tissue Androgenic - secondary male sexual characteristics
  • 12. 0 0.2 0.4 0.6 0.8 1 1.2 last year Ever YP last year “Have you ever taken anabolic steroids (steroids) (not prescribed by a doctor) even if it was a long time ago?” Anabolic steroid use in last year/ever Adults ever 356,000 (302,000 – 411,000) Adults last year 61,000 (38,000 – 83,000) YP last year 23,000 (5,000 – 40,000)
  • 13. ‘All’ & ‘new’ clients attending agency based NSPs in Liverpool City Region (1991 to 2011) 0 500 1,000 1,500 2,000 2,500 3,000 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 Number of Clients Year of Presentation/Attendance New AS injecting clients New other injecting clients AS injecting clients Other injecting clients
  • 14. Middlesbrough 67% Kirklees 60% Sheffield 62% Newcastle 52% Sunderland 60% Bradford 41% Halton 86% Liverpool 83% Sefton 43% St Helens 34% Warrington 86% Wirral 77% Manchester 60% Bolton 52% NSP clients using anabolic steroids in Northern England (Kimergard & McVeigh, 2014)
  • 15. Anabolic steroid users accessing NSPs in Cheshire and Merseyside, UK (1995 and 2015) (McVeigh & Begley, 2017)
  • 16. Anabolic steroid users attending NSPs in Liverpool City Region (1995 and 2015) 1995 2015 Number of anabolic steroid NSP clients 553 2446 Proportion of NSP clients 17% 55% Syringes provided to steroid users 14,293 139,956 Mean syringes per steroid user 26 57 (McVeigh & Begley, 2017)
  • 18. Adverse effects on several organ/systems in particular: Cardiovascular effects Haematologic effects Psychiatric and neuropsychologic effects Hormonal and metabolic effects Variety of less frequent effects on various other bodily tissues. Pope et al, 2013 Adverse Health Consequences of Performance Enhancing Drugs An Endocrine Society Scientific Statement
  • 19. Bilateral deltoid abscesses pre-operative clinical appearance Marquis & Maffulli, 2006
  • 20. Marquis & Maffulli, 2006 Intra-operative drainage
  • 21. 2010/11 2012/13 Anti-HIV Prevalence 1.5% (400) 2.0% (249) Anti-HBc Prevalence 8.7% (400) 2.8% (249) Anti-HCV Prevalence 5.4% (400) 3.6% (249) Level of sharing (direct & indirect) 8.9% (392) 13% (243) Hepatitis B vaccine uptake 24% (375) 40% (246) Symptom of injection site infection 6.9% (389) 16% (238) Ever been in prison 17% (377) 24% (247) Unlinked Anonymous Monitoring Survey of People Who Inject image and performance enhancing drugs Hope, McVeigh et al, 2014
  • 22. 22 From Glass R et al Secondary distribution of injecting equipment obtained from needle and syringe programmes by people injecting image and performance enhancing drugs: England & Wales, 2012-15. One in three of people using IPEDs who use NSP distribute equipment to others
  • 23. Mid-point: 160 participants 1,040 others Estimated extend of secondary distribution There were 564 participants in the sample. 160 collected for others. Minimum: 160 participants 667 others 23 Range of users which may not be engaging with NSP from our sample Glass R et al Secondary distribution of injecting equipment obtained from needle and syringe programmes by people injecting image and performance enhancing drugs: England & Wales, 2012-15.
  • 24. 24 14% 86% Ever injected a psychoactive drug Yes No 46% 54% Injected psychoactive drugs during last year Yes No Hope et al. Drug and Alcohol Dependence 2017;179 :83-86 Injection of psychoactive drugs
  • 25. Prevalence of antibodies to hepatitis C Overall one in twenty had antibodies 25 1.4% 39% 14% 0% 25% 50% 75% 100% Never injected a psychoactive drug Recently (in preceding 12 months) injected a psychoactive Previously injected a psychoactive Hope et al. Drug and Alcohol Dependence 2017;179 :83-86
  • 26. Awareness of having had hepatitis C 26 Hope et al. Drug and Alcohol Dependence 2017;’, 179 :83-86 0 5 10 15 20 Never injected a psychoactive drug Recently (in preceding 12 months) injected a psychoactive Previously injected a psychoactive Aware Unaware
  • 28. 993 male anabolic steroid users 96 250 525 104 Other 17 Global Drug Survey 2015 (89,509 responses) Zahnow et al (2017)
  • 29. Region of residence: AAS users as proportion of GDS participants Characteristics Total males Ever used % of total males ever used Used in the last 12 months % of total male used in last 12 months Region Europe 47,424 525 (1.10) 158 (0.33) North America 3,038 96 (3.06) 27 (0.86) South Americas 3,133 250 (7.39) 84 (2.48) Oceania 4,080 104 (2.49) 38 (0.91) Other 537 17 (3.07) 8 (1.44) Total 58,212 993 (1.68) 315 (0.53) Zahnow et al (2017)
  • 30. Global Drug Survey – 993 steroid users Drug Used in last 12 months Lifetime use Cannabis 63.1 87.8 Other drugs * 44.6 71.4 Ecstasy 41.8 61.3 Cocaine 38.7 61.3 Amphetamines 20.6 49.1 LSD 18.1 41.1 Benzodiazepines 28.2 34.8 NPS 14.0 31.0 Opiates 15.3 30.0 * Including magic mushrooms, poppers, nitrous, ketamine and GHB Zahnow et al (2017)
  • 31. Hope, V. D., McVeigh, J., Smith, J., Glass, R., Njoroge, J., Tanner, C., . . . Desai, M. (2017). Low levels of hepatitis C diagnosis and testing uptake among people who inject image and performance enhancing drugs in England and Wales, 2012-15. Drug and Alcohol Dependence, 179, 83-86. McVeigh, J., & Begley, E. (2017). Anabolic steroids in the UK: an increasing issue for public health. Drugs: Education, Prevention and Policy, 24.:3, 278-285 Hope, V. D., McVeigh, J., Marongiu, A., Evans-Brown, M., Smith, J., Kimergard, A., . . . Bellis, M. A. (2013). Prevalence of, and risk factors for, HIV, hepatitis B and C infections among men who inject image and performance enhancing drugs: a cross-sectional study. BMJ OPEN, 3(9), 11 McVeigh, J., Beynon, C., & Bellis, M. A. (2003). New challenges for agency based syringe exchange schemes: Analysis of 11 years of data (1991-2001) in Merseyside and Cheshire, United Kingdom. International Journal of Drug Policy, 14(5-6), 399-405. Zahnow, R., McVeigh, J., Ferris, J., & Winstock, A. (2017). Adverse effects, health service engagement, and service satisfaction among anabolic androgenic steroid users. Contemporary Drug Problems 44(1):69-83 01 Hope, V. D., Harris, R., McVeigh, J., Cullen, K. J., Smith, J., Parry, J. V., . . . Ncube, F. (2016). Risk of HIV and Hepatitis B and C Over Time Among Men Who Inject Image and Performance Enhancing Drugs in England and Wales: Results From Cross-Sectional Prevalence Surveys, 1992-2013. JAIDS, 71(3), 331-337 Hope, V. D., McVeigh, J., Marongiu, A., Evans-Brown, M., Smith, J., Kimergard, A., . . . Ncube, F. (2015). Injection site infections and injuries in men who inject image- and performance-enhancing drugs: prevalence, risks factors, and healthcare seeking. Epidemiology and Infection, 143(1), 132-140. McVeigh, J., bates, G., & chandler, M. (2015). Steroids and Image Enhancing Drugs 2014 Survey Results. http://www.cph.org.uk/wp- content/uploads/2015/07/SIEDs-report-GB-JL-10-7-15-Final.pdf Bates, G., & McVeigh, J. (2016). Image and Performance Enhancing Drugs 2015 Survey Results. Liverpool: Liverpool John Moores University. http://www.cph.org.uk/wp-content/uploads/2016/07/IPEDs-2015-survey_final1.pdf Kimergard, A., & McVeigh, J. (2014). Environments, risk and health harms: a qualitative investigation into the illicit use of anabolic steroids among people using harm reduction services in the UK. BMJ Open, 4(6), References
  • 32. Jim McVeigh Director Public Health Institute Liverpool John Moores University 0151 231 4512 j.mcveigh@ljmu.ac.uk