This document discusses pharmacokinetics and distribution of drugs in the body. It defines distribution as the reversible transfer of a drug from one location to another within the body. Once a drug enters systemic circulation through absorption or direct administration, it gets distributed into interstitial and intracellular fluids, with each organ or tissue receiving different doses of the drug and retaining it for varying amounts of time. The document appears to be part of a larger work on principles of pharmacology, pharmacokinetics, and pharmacodynamics.

1. Pharmacokinetics
mr. B.chakraPani m.Pharm (LLB)
associate Professor
DePartment of PharmacoLogy
BaLaji coLLege of Pharmacy
anantaPur

36. Distribution in pharmacology is a branch of pharmacokinetics which
Describes the reversible transfer of a Drug from one location to
another within the boDy.
once a Drug enters into systemic circulation by absorption or Direct
aDministration, it must be DistributeD into interstitial anD
intracellular fluiDs. each organ or tissue can receive Different Doses
of the Drug anD the Drug can remain in the Different organs or tissues
for a varying amount of time

39. principles of
pharmacology
pharmacokinetics
&
pharmacoDynamics