This document discusses various types of personal dosimeters used to measure radiation exposure, including film badges, pocket chambers, pocket dosimeters, and TLDs (thermoluminescent dosimeters). Film badges use multiple filters and sensitive films to measure different types of radiation. Pocket chambers and dosimeters can measure accumulative doses more frequently but require charging. TLDs measure light emitted from crystals when heated to determine exposure and can store doses over long periods. The document provides details on the components, operation, advantages, and disadvantages of each dosimeter type.
Basic Radiation Safety Awareness Training
History of Radiation
Natural and Man-Made Background Sources of Radiation
Fundamentals
Exposure Limits & Regulations
Detection of Radiation
Safe Practices with Radiation
Biological Effects of Radiation
Where to Find Further Information
This article illustrates the principle and working of Colorimeter and Photometer and how absorbance, transmittance and light intensity can be measured.
The era of lamp photobiological safety standards coincided with a proliferation of solid state lighting applications, which led to much discussion on the retinal blue light hazard posed by these sources and much confusion in the interpretation of the EN 62471 standard.
Driven by the desire to circumvent issues encountered in applying this standard, and to reduce the measurement burden of luminaire manufacturers, a new approach to the evaluation of the photobiological safety of luminaires is now in place, according to the latest edition of the luminaire standard, EN 60598-1.
Whilst the new approach includes techniques to perform an analysis based on readily available information, in accordance with the reduction of measurement burden, it will be seen that this approach may lead to overly conservative results. It will also be shown that, in the analysis of sources with high blue light radiance, the determination of hazard distance may in many cases be over-estimated.
Hazard distance is rarely readily calculable for extended sources and determination by measurement can be cumbersome but can give a well-defined framework of assessment which will dispel the interpretations and uncertainties that has plagued lamp photobiological safety standards hitherto. A simple measurement-based approach is proposed.
Talk by Leslie Lyons MPhys, Bentham Instruments Limited
Basic Radiation Safety Awareness Training
History of Radiation
Natural and Man-Made Background Sources of Radiation
Fundamentals
Exposure Limits & Regulations
Detection of Radiation
Safe Practices with Radiation
Biological Effects of Radiation
Where to Find Further Information
This article illustrates the principle and working of Colorimeter and Photometer and how absorbance, transmittance and light intensity can be measured.
The era of lamp photobiological safety standards coincided with a proliferation of solid state lighting applications, which led to much discussion on the retinal blue light hazard posed by these sources and much confusion in the interpretation of the EN 62471 standard.
Driven by the desire to circumvent issues encountered in applying this standard, and to reduce the measurement burden of luminaire manufacturers, a new approach to the evaluation of the photobiological safety of luminaires is now in place, according to the latest edition of the luminaire standard, EN 60598-1.
Whilst the new approach includes techniques to perform an analysis based on readily available information, in accordance with the reduction of measurement burden, it will be seen that this approach may lead to overly conservative results. It will also be shown that, in the analysis of sources with high blue light radiance, the determination of hazard distance may in many cases be over-estimated.
Hazard distance is rarely readily calculable for extended sources and determination by measurement can be cumbersome but can give a well-defined framework of assessment which will dispel the interpretations and uncertainties that has plagued lamp photobiological safety standards hitherto. A simple measurement-based approach is proposed.
Talk by Leslie Lyons MPhys, Bentham Instruments Limited
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Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
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Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
3. Summary
Introduction of dosimetery
Introduction of personal dosimeters
Film badge - structure
- advantage & disadvantages
- function
Pocket chamber - structure
- reading & charging
Pocket dosimeter - structure
- reading & charging
TLD
New device for personal dosimetry 3
4. Ionization radiation
Not audible, not visible
Product ion , biological effects happen with delay
Dosimetery : description of radiation beam &
effects on environment
Exposure: producted pair ion in the air(Rontgen)
Dose & Kerma : absorbed dose per Kg (Gy)
4
8. Personal monitoring
People who are exposed by ionizing radiation need
personal monitoring programs.
Personnel should wear dosimeter when the
possibility of such exposure exists.
Personal monitoring isn’t radiation protection
instrument ; but it is a method for measuring
radiation.
8
11. Introduction
The primary personal dosimetry instrument
Determining x-ray , gamma, beta, and neutron
Is changed for twice a month
Range of radiation: 5-500 mR
11
14. Inside structure
Film : measuring radiation through density
Opening window : determine beta beams
7 filters : allow some energy types to pass,
while blocking others
14
15. Film
At the core of a dosimeter badge
Reacting to radiation & is surrounded by a case
to prevents from light & moisture
A badge contain:
- several films of different sensitivities
OR
- single film with multiple emulsion coating
15
16. Filter
Choosing filter depend on the kind of
radiation
The purpose of using them is determining
types of radiation
16
17. Filter cont.
Plastic filter : 50 mg/cm²
Plastic filter : 300 mg/cm²
Alloy of Al & Cu
Alloy of Cd & Pb
Alloy of Sn & Pb
Lead border
Indium
17
18. Advantages
Inexpensive
Easy to use
Providing a permanent record
Requiring no technical knowledge
Less vulnerable than the other methods of
dosimetry
Determining the types & amount of radiation
energy to predict the biological consequences
18
19. Advantages cont.
Show the direction of radiation
Judging the standards of environment
Distinguish the primary radiation from scatter
High spatial resolution
19
20. Disadvantage
Non reusable
Failure to detect low-energy beams
It is not accurate for any exact measurement
Isn’t used for long time
Less sensitivity in comparison with the other
personal dosimeter devises
No immediate diagnosis
Sensitivity decrease outside the energy range
50kv
21. How do you use them?
Its number is specified for a person
Badge shouldn’t have more or less part
Film must not have holes
Film-badge is worn in front of the chest
Film-badge must not exposure by ionizing
beam when you don’t use it.
21
22. Operation
Film-badge measure radiation when ionizing
radiation confront with silver halide
Film density is depend on quantity of radiation
Photoelectrical densitometer read film density
Small change of emulsion cause large change in
quantity repliment to radiation
22
28. Inside structure
Act as an air-filled condenser like thimble -
chamber
Calibrated by Cs , Co , Ra gamma radiation
Insulator is penetrated at one end to serve as
charging contact
28
29. Inside structure cont.
Has 2 electrodes:
- aluminum rod as central electrode
- chamber’s outer wall as second electrode
The central electrode was suspended at each
end with a polyethylene insulator
29
30. How it works ?
Voltage depressure is the base of pocket chamber
Electrical discharge is proportional to ionization
Pocket chambers need to be charge after reading
30
40. How it works?
charge of anode by positive potential
distributed between wire & fiber
quartz fiber deflected by electrostatic
repulsion
Greater charge cause greater deflection
Radiation produce ionization and electron
40
41. How it works? (Cont.)
electrons attracted to , & collected by
positively charged central anode
electron collection reduce the net positive
charge
In result, quartz fiber return to right position
Fiber movement is proportional to ionization
41
42. Reading & Charging
pocket dosimeter
Pointing dosimeter at a light source
Looking through lenses
Fiber is viewed on a graduated translucent
scale
42
43. Reading & Charging
pocket dosimeter
(Cont.)
Pocket dosimeters charge by handheld
charger through squeezing the lever
Dosimeter placed in or remove from charger
by pulling a trigger
Clamping action hold dosimeter
43
44. pocket chamber vs. pocket dosimeter
pocket chamber needs to reader instrument
pocket dosimeters are larger
Pocket dosimeter are more energy dependent
pocket chambers were far less expensive
pocket chamber is more reliable
chamber dosimeter have to be charged every
time they were read
For military purposes chamber dosimeter is
desirable
44
45. Properties
Is absolute , stable, directional dependence &
user friendly device
Accuracy: within ±1% of true exposure
Ranges: 0-200 mRem , 0-600 mRem
Temperature range: -20 °C – 50 °C
Relative humidity: up to 90%
45
50. Introduction
A thermo luminescent dosimeter, or TLD, is a type
of radiation dosimeter.
A TLD measures ionizing radiation exposure by
measuring the amount of visible light emitted from a
crystal in the detector when the crystal is heated.
The amount of light emitted is dependent upon the
radiation exposure.
50
52. TLD forms
common types of TLD are:
Bulk granulated
Compressed pellets or “chips”
Teflon matrix
Single-crystal plates
Powder enclosed in plastic tubing that can be heated
52
54. Personal dosimetery by TLD
Ability to store doses over long periods.
It can be read by automated system and is fast.
It can be held in film badge holder.
Low doses can be measured.
54
55. Advantages
Small size
Wide useful dose range, from a few millirads to ~103 rad
Economy. Reusability usually reduces cost per reading
TLD phosphors can normally be reused many times until they
become permanently damaged by radiation, heat or
environment.
Readout convenience
55