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z
This slide is made with the assistance of Medicos
PDF app:
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Pelvic inflammatory
disease (PID) salpingitis
z
Pathophysiology
• Acute inflammation of the upper genital tract – the
uterus or adnexa – from an ascending infection –
usually chlamydia or gonorrhea (25%). May lead to
epithelial damage thus allowing further pathogen entry.
• Involves any combination of endometritis, salpingitis,
tubo-ovarian abscess, or pelvic peritonitis.
• Rarer causes: Gardnerella vaginalis, H. influenzae, Strep
agalactiae (Group B Strep), CMV.
• Often no pathogen is found.
z
PID
Medicos
Slides:
z
Signs and symptoms
 Symptoms:
• Varies from asymptomatic to severe.
• Pain: lower abdominal (often bilateral), lower back, and
deep dyspareunia.
• Systemic: fever, nausea and vomiting.
• Discharge and bleeding: cervical or vaginal mucopurulent
discharge, postcoital or intermenstrual bleeding.
 On bimanual examination, tenderness in the uterus,
adnexa, and cervix ('cervical excitation').
z
Risk factors
• Sexually active, especially if unprotected.
• History of STIs.
• Age 18-25.
• IUCD
z
Investigations
 Initial tests:
• Bloods: ↑WBC, ↑ESR/CRP.
• Vaginal or endocervical swabs: send for chlamydia and
gonorrhea nucleic acid amplification test.
• Urine: rule out UTI, and pregnancy test to rule out
ectopic.
z
Investigations
 Optional further tests:
• Transvaginal US may show fluid-filled fallopian tubes,
endometrial thickening, or tubo-ovarian abscess. Also helps
rule out other conditions.
• Screen for other STIs.
• Consider pelvic CT or MRI if severe.
• Laparoscopy can help make the diagnosis and rule out
alternative causes, but is invasive and not routinely used.
z
Investigations
 Diagnosis:
• Can often be made clinically, especially as swabs may be
negative even if PID present.
• However, PID is unlikely if WBC, ESR, and swabs are
normal.
z
Medicos PDF app:
z
Management
 Antibiotics:
• Ceftriaxone IM once, then doxycycline PO ± metronidazole PO for
2 weeks.
• If severe – >38°C, peritonitis, or abscess – give ceftriaxone IV +
metronidazole IV + doxycycline PO, then switch to metronidazole
PO + doxycycline PO.
• Screen and treat sexual contacts.
 Also:
• Analgesia
• Consider removing IUCD, but balance against risks of pregnancy.
• Repeat testing 3-6 months later to ensure no recurrence.
z
Complications
• Scarring and adhesions to nearby tissue or organs,
causing chronic pain.
• Tubo-ovarian abscess.
• Fitz-Hugh Curtis syndrome (10%): RUQ pain due to
perihepatitis.
• Obstetric: infertility, ectopic pregnancy.
z
Thank You
 Keep supporting Medicos PDF app. To find hundreds of books,
slides and news visit the app.
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Pelvic inflammatory disease (pid)

  • 1. z This slide is made with the assistance of Medicos PDF app: https://bookapp.page.link/slideshare Pelvic inflammatory disease (PID) salpingitis
  • 2. z Pathophysiology • Acute inflammation of the upper genital tract – the uterus or adnexa – from an ascending infection – usually chlamydia or gonorrhea (25%). May lead to epithelial damage thus allowing further pathogen entry. • Involves any combination of endometritis, salpingitis, tubo-ovarian abscess, or pelvic peritonitis. • Rarer causes: Gardnerella vaginalis, H. influenzae, Strep agalactiae (Group B Strep), CMV. • Often no pathogen is found.
  • 4. z Signs and symptoms  Symptoms: • Varies from asymptomatic to severe. • Pain: lower abdominal (often bilateral), lower back, and deep dyspareunia. • Systemic: fever, nausea and vomiting. • Discharge and bleeding: cervical or vaginal mucopurulent discharge, postcoital or intermenstrual bleeding.  On bimanual examination, tenderness in the uterus, adnexa, and cervix ('cervical excitation').
  • 5. z Risk factors • Sexually active, especially if unprotected. • History of STIs. • Age 18-25. • IUCD
  • 6. z Investigations  Initial tests: • Bloods: ↑WBC, ↑ESR/CRP. • Vaginal or endocervical swabs: send for chlamydia and gonorrhea nucleic acid amplification test. • Urine: rule out UTI, and pregnancy test to rule out ectopic.
  • 7. z Investigations  Optional further tests: • Transvaginal US may show fluid-filled fallopian tubes, endometrial thickening, or tubo-ovarian abscess. Also helps rule out other conditions. • Screen for other STIs. • Consider pelvic CT or MRI if severe. • Laparoscopy can help make the diagnosis and rule out alternative causes, but is invasive and not routinely used.
  • 8. z Investigations  Diagnosis: • Can often be made clinically, especially as swabs may be negative even if PID present. • However, PID is unlikely if WBC, ESR, and swabs are normal.
  • 10. z Management  Antibiotics: • Ceftriaxone IM once, then doxycycline PO ± metronidazole PO for 2 weeks. • If severe – >38°C, peritonitis, or abscess – give ceftriaxone IV + metronidazole IV + doxycycline PO, then switch to metronidazole PO + doxycycline PO. • Screen and treat sexual contacts.  Also: • Analgesia • Consider removing IUCD, but balance against risks of pregnancy. • Repeat testing 3-6 months later to ensure no recurrence.
  • 11. z Complications • Scarring and adhesions to nearby tissue or organs, causing chronic pain. • Tubo-ovarian abscess. • Fitz-Hugh Curtis syndrome (10%): RUQ pain due to perihepatitis. • Obstetric: infertility, ectopic pregnancy.
  • 12. z Thank You  Keep supporting Medicos PDF app. To find hundreds of books, slides and news visit the app. https://bookapp.page.link/slideshare