Gastroenteritis is an inflammatory disease of the stomach and intestines characterized by sudden onset of diarrhea and vomiting. It is commonly caused by viruses, bacteria, parasites, and other non-infectious agents. The main symptoms include diarrhea, fever, abdominal cramps, and dehydration. Treatment involves oral rehydration therapy to replace lost fluids based on the level of dehydration, along with continued breastfeeding and nutritional supplements. Antibiotics may be given for specific bacterial infections. The goal of management is to prevent and treat dehydration through oral or intravenous fluid replacement.
This presentation focuses on Acute Bacterial Meningitis.
Viral and fungal cause is mentioned but focus is on bacterial meningitis in Pediatrics Patient.
Feel free to correct if there is any error.
Refer to other reference books for clarity.
This presentation focuses on Acute Bacterial Meningitis.
Viral and fungal cause is mentioned but focus is on bacterial meningitis in Pediatrics Patient.
Feel free to correct if there is any error.
Refer to other reference books for clarity.
Is defined as diarrhea with visible blood in
stools.
The most important and frequent cause of
acute dysentery is Shigella. Other causes
include Campylobacter jujeni, Salmonella,
and enteroinvasive E. coli.
Entameba histolytica causes dysentery in
older children but rarely in children under 5
years of age
Dysentery is specially sever in :-
1. Malnourished infants and children.
2.Those who develop clinically evident
dehydration during their illness. 3. Those who
are not breast fed. 4. Children with measles
or had measles in the preceding month.
5. Those who present with convulsion or
develop coma.
Acute infectious diarrhea
Seminar Prepared by :-
Mohammed Musa
Mohammed Saadi
Hussein Jassam
Mahmoud Ahmed
Meran Salih
Internal Medicine
College of Medicine - University of Kirkuk
Defined as inflammation of the mucous membrane of stomach and intestine usually causing nausea ,vomiting and diarrhea.
Gastro-intestinal infections represent a major public health and clinical problem worldwide. Many species of bacteria, viruses and protozoa cause gastro-intestinal infection.
Diarrhea and vomiting in children
Vomiting (throwing up) and diarrhea (frequent, watery bowel movements) can be caused by viruses, bacteria, parasites, foods that are hard to digest (such as too many sweets) and other things.
Diarrhea is loose, watery stools. Having
diarrhea means passing loose stools three or more times a day. Acute diarrhea
is a common problem that usually lasts 1 or 2 days and goes away on its own.
Diarrhea lasting more than 2 days may be a
sign of a more serious problem. Chronic diarrhea—diarrhea that lasts at least 4
weeks—may be a symptom of a chronic disease. Chronic diarrhea symptoms may be
continual or they may come and go.
Diarrhea of any duration may cause
dehydration, which means the body lacks enough fluid and electrolytes—chemicals
in salts, including sodium, potassium, and chloride—to function properly. Loose
stools contain more fluid and electrolytes and weigh more than solid stools.
People of all ages can get diarrhea. In the
United States, adults average one bout of acute diarrhea each year, and young
children have an average of two episodes of acute diarrhea each year.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
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Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
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TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
3. DEFINITION;Gastroenteritis is an
inflamatory disease of the gastric,and
enteric sites of the gastrointestinal tract.
It is characterised by a sudden onset of
diarhea with or without vomiting.
Diarhea in infants and small children may
quikly dehydrate or get hypovolemic shock
if fluids and electrolytes are not admistered
immediately.
Causes include;virus,bacteria,protozoal,and
non infectious causes.
4. 1.Viral causes.
Viruses account for the largest causes
of diarhea in pediatrics
Rotavirus is the leading viral pathogen
worldwide.
Others;calivirus,astovirus,norovirus,an
d adenovirus in gastroenteritis.
6. 2.Bacterial agents
Also called food poisoning.
Bacteria is the second leading cause
of diarhea in peaeiatrics.
Compylobacter Jejuni is the leading
bacterial cause of gastroenteritis
developed countries.
Other forms of bacteria
include;shigella,Enterohemorhagic
Escherichia coli,and salmonella
enterica in developed countries.
7. In developing
countries;Enterotoxigenic ecoli is the
leading cause of gastroenteritis of the
paediatrics.
Others include;compylobacter
jejuni,shigella and salmonela enterica.
9. 3.History of antibiotics use.
A history of recent use of antibiotics
like;penicillins,cephalosporins,and
clyndamycim, to the pediatrics may
increase the likelyhood of toxix
chlostridium difficile infexion,which
causes gastroenteritis.
50% of neonates are colonised with
chlostridium difficile hence
symptomatic diesease is unlikely to
occur in them.
10. 4.Parasites
A number of protozoans like;Giardia
lamblia,Entamoeba hystolitica,and
crystosporidium,remain the leading
cause of gastroenteritis inpaediatrics.
Symptoms include;watery stool,and
travel to an endemic area.
11. Transmission.
Bottle feeding of babies with
unsanitized bottles.
Poor hygiene among children in
crowded areas.
Prexisting poor nutritional status.
13. Pathophysiology of
gastroenteritis.
GE is defined as vomiting or diarhea due
to infections of the small or large
intestines.
Changes are majorly non-inflammatory,in
the small intestines,but inflammatory in
large intestines.
Abdominal crambs,increased thirst,due
to excessive water dehydration and
scanty urine occurs.
Most dangerous symptoms include,high
fever above 38.9 degrees celcius,blood
or mucus in the diarhea,blood in the
vomit,and severe abdominal pains or
swellings.
14. cntd, Phathophysiology
Most of the infective microrganisms
mentioned like;viruses,bacteria,and
protozoans,damage the mucosal lining
or the brushborder in the small
intestines.
Loss of protein-rich fluids and decreased
ability to absorb the lost fluids occurs.
Invasion of the intestinall wall may cause
bleeding especially incase of
shigella,E.hystolytica and salmonella
enterica.
Loss of a lot of water salts causes
dehydration.
15. TYPES OF DIARRHEA.
A.Secretory diarrhea.
Caused by increased active secretion
or due to inhibition of absorption.
Occurs due to secretion of anions
especially the chloride ions.
Main cause is cholera toxins.
Intestinal fluid secretion is isotonic
with plasma even during fasting.
To maintain a charge balance in the
lumen,sodium is carried along with
water.
16. 2.Osmotic diarrhea.
Occurs when water is drawn into the
bowels.
Excessive drinking of fluids with
excess sugar and salt may also be a
cause.
May also result from mal-absorption
e.g pancreatic disease or celiac
disease.
Laxatives,constipation,or too much of
magnesium,vitamin c,or undigested
17. 3.Motility related diarrhea.
Hypermotility diarrhea.
Due to hypermotility of the
intestines,no sufficient time for
sufficient nutrient and water
absorption.
Its may be due to a vagotomy or
diabetic neouropathy.
18. 4.Exudative diarrhea.
Caused by presence of pus and blood
in the lumen.
Occurs with inflammatory bowel
disease like chrohns
disease,ulcerative colitis,and severe
infections like E.coli.
19. 5.Inflammatory diarrhea.
Occurs due to the mucosal damage to
the mucosal lining or brush
border,causing passive loss of protein-
rich fluids and a decreased ability to
absorb the lost fluid.
Majorly due to viral infections,parasitic
infections,or autoimmune problems.
20. 6.Dysentery.
It’s a blood stained diarrhea.
Blood presence indicates invasion of
the bowel tissue by microrganisms like
shigella,Entamoeba hystolitica and
salmonella enterica.
21. 7.Infectious diarrhea.
Mainly caused by virus,and bacteria.
Norovirus,rotavirus,and adenovirus
are the most significant causes of viral
diarrhea.
Compylobacter spp. Is the most
common cause of bacterial diarrhea.
Salmonella,shigella spp.and some
strains of E.coli too contribute as
causative agents.
22. Diagnostic investigations of
GE.
Stool samples are collected for
microscopy.A stoll sample in viral GE
does not contain any recognisable
exudate,and its free from inflamatory
cells,blood and fibrin.
Presence of leukocytes indicates
presence of bacterial agent.
Cysts and trophozoites indicate parasitic
GE.
Blood tests for;FBC,renal function and
electrolytes can also be done to rule any
systemic effects.
Blood culture if giving antibiotics therapy.
23. Dehydration due to diarrhea
according to WHO.
Dehydration is defined as an incident
in which water and
electrolytes(sodium,pottasium,and
bicarbonate)are lost through liquid
stools,vomit,sweat,urine and
breathing.
Dehydration occurs when these losses
are not replaced.
24. Classification of dehydration.
1.Early dehydration .The body has lost about 2%of its total
fluids.No signs or symptoms.
2.Moderate dehydration.Its characterised by;
Thirst
Restless or irritable behaviour.
Decreased skin elasticity.
Sunken eyes.
Decreased urine output.Less than six diapers in babies
and eight hours of older children without urination.
Few or no tears when crying.
Lghtheadedness or dizziness.
Sleeplessnes or tiredness.
Muscle weaknes.
25. 3.Severe dehydration.
Its characterised by;
1. Shock
2. Diminished consciousnes and delirium.
3. Little or no urine output.
4. Cool and moist extremities
5. Low blood pressure
6. Sunken eyes.
7. Very dry mouth,mucus membranes.
8. Infants will have sunken fontanels.
9. Shrivelled and dry skin which lacks
elasticity.
26. Management of
gastroeneritis.
According to(Integrated management of
child illnesses,IMCI)Protocol plan A,B
and C.
Plan A;Management of the
dehydration.Fluid management.
A. Early dehydration.
a) Rehydration therapy is not required.
b) Replacement of losses.Less than
10kgs,give 60-120 oral dehydration
solution for each diarrhea stool or
vomiting episode.
28. B.Moderate dehydration.
Rehydration therapy.Give oral
rehydration solution 50 to 100mls/kg
for 3 to hours.
Replacement of losses.Less than
10kgs body weight,60 to 120mls oral
ryhydration solutions for each
diarrhea stool or vomiting episode.
Those who are more than 10kgs, body
weight 120 to 140 mls,oral rehydration
solution for each diarrhea stool or
vomiting episode.
29. Severe dehydration
management.
Rehydration therapy.Adminster
intravenous Ringers lactate or
N/S(20mls per kg)untill perfusion and
mental states improve,followed by
100ml/kg oral rehydration salution
over four hours,or 50% dextrose half
N/S intravenous at twice maintenance
rates.
30. Replacement therapy.
10kgs,body weight 60 to 120mls oral
rehydration solution for dehydration
stool or vomiting episode.
More than 10kgs body weight give 120
to 140 mls,oral rehydration solution for
each diarhea stool or vomiting
episode.
If unable to drink adminster through
nasogastric tube or intravenously
adminster 5% dextrose on fourth
N/S,with 20mEq/L pottasium chloride.
31. Plan B;Medical management.
Compylobacter spp,its treated with Erythromycin.
Clostridium difficile,discontinue the causative
antibiotic.If antibiotics cant be stopped,oral
mentronidazole or vancomycin is adminstered.
Entamoeba hystolytica;metronidazole followed by
iodoquimol,or paramomycin.
E.coli;sulfamethoxazole in moderate
diarrhea,while third and fourth cephalosporin are
indicated for systemic complications.
Zinc suplements are given to reduce severity of
diarrhea,10-20mg/day for 10-14 days for chidren
younger 5yrs.
Don’t give antidiarrheal drugs.
32. Plan C;Nutritional
management.
During rehydration therapy;
Continue breast feeding.
Don’t give solid foods.
In children without flag symptoms and
signs,don’t routinely give oral fluids
other than ORS,however consider
supplementation with the childs
fluids;breast milk or water but not fruit
juices or carbonated drinks,if they
refuse the ORS solution.
33. Cntd,
In children with red flag symptoms or signs,don’t
give oral fluids other than ORS SOLUTION.
After rehydration;Give full-strength milk straight
away.
Re-introduce the childs usual solid foods.
Avoid giving fruit juices and carbonated drinks
until the diarrhea has stopped.
NB;Not all commercial ORS formulas promote
optimal absorption of electrolytes,water and
nutrients.
An ideal solution should have an osmolarity
of(210-250)and sodium content of 50-
60mmol/litre.
WHO recomends use of the ORT form of ORS.