Pediatric cervical injuries
AHMAD ALTHEKAIR, MD
CONSULTANT, PEDIATRIC EMERGENCY AND TRAUMA
Objectives
 Epidemiology
 Mechanism of injury
 Clinical presentation
 Approach
 Clinical vs. radiological clearance
 Current evidence
Incidence
Annually 30-46/1,000,000
Males 60-80%
MVCs
35%
Falls
25%
MVC vs.
pedestrian
20%
Diving
6%
sports
14%
LEONARD ET AL, PEDIATRICS VOLUME 133, NUMBER 5, MAY 2014
Age variation
<8 years are susceptible to higher cervical injuries (C1-C3) because of:
1. Larger heads than bodies
2. Position of C-spine fulcrum
3. Weaker cervical muscles
4. Increased laxity of ligaments
5. Immature vertebral joints
Anatomical predispositions
Causes
Mechanism of injury
COURTESY OF ALISON CHANTAL CAVINESS, MD.
Evaluation
Symptoms:
◦ Classic triad of: local pain, muscle spasm, and decreased range of motion of
the neck.
◦ Also may complain of transient or persistent paresthesia or weakness.
◦ A retrospective review of 72 previously normal children with cervical spine
injury found that all those with asymptomatic injuries had both a high-risk
injury mechanism and a distracting injury.
◦ “Burning hand syndrome”
“Neck immobilization should be maintained during evaluation and
management”
BAKER ET A, AM J EMERG MED. 1999;17(3):230.
Evaluation
Physical Examination:
◦ Vital signs, Neck exam and
Neurologic exam.
In toddlers and infants with minor
trauma and normal neurological
exam; palpate C-spine and assess
ROM. If normal, clinically cleared.
NEXUS criteria
1. No cervical midline tenderness
2. No focal neurological deficit
3. No intoxication
4. Normal alertness
5. No painful distracting injuries
 34,069 trauma victims in 21 nation-wide Emergency departments had 99%
sensitivity for C-spine injuries and 99.6% for clinically significant C-spine
injuries in adults.
HOFFMAN ET AL, N. ENGL. J. MED. 2000;343:94-9
Limitations in Pediatric
 3,065 children were involved, 30 had C-spine injuries.
 Sensitivity 100% , Specificity 19.9%.
 None of the children studied was younger than 2 years, and only 817 (27%)
were younger than age 8 years .
PEDIATRICS 2001;108:E20
Further studies
 Single-center, 20-year review applied the NEXUS criteria to 190
children with significant cervical spine injury found that the criteria
were 94% sensitive among children aged less than 8 years and 100%
sensitive in those greater than age 8 years.
 A Pediatric Emergency Care Applied Research Network (PECARN)
study found that the NEXUS criteria were 83% sensitive among 539
children with spinal injury who presented to the emergency
department. Of the 90 children missed by the NEXUS criteria, 58 (64%)
were younger than 8 years of age.
GARTON ET AL, NEUROSURGERY 2008;62:700-8
LEONARD ET AL, ANN EMERG MED 2011 AUG;58(2):145-55
Canadian C-spine Rules
Canadian C-spine vs. NEXUS
Canadian C-spine NEXUS
Sensitivity 99.4% 90.7% P<0.001
Specificity 45.1% 36.8% P<0.001
Radiography rates 55.9% 66.6% P<0.001
 The Canadian C-spine Rule would have missed 1 patient and the NEXUS
would have missed 16 patients with important injuries.
 But, both are not meant for pediatric population.
STIELL ET AL, N ENGL J MED 2003; 349:2510-2518
Trauma Association of Canada
CHUNG ET AL, TRAUMA ASSOCIATION OF CANADA PEDIATRIC SUBCOMMITTEE NATIONAL PEDIATRIC CERVICAL SPINE EVALUATION
PATHWAY: CONSENSUS GUIDELINES. J TRAUMA 2011
Trauma Association of Canada
CHUNG ET AL, TRAUMA ASSOCIATION OF CANADA PEDIATRIC SUBCOMMITTEE NATIONAL PEDIATRIC CERVICAL SPINE EVALUATION
PATHWAY: CONSENSUS GUIDELINES. J TRAUMA 2011
Radiological evaluation
 Children with suspected cervical spine injury based on history or physical
examination must undergo radiologic evaluation (Cross-table lateral, AP
and when obtainable open-mouth odontoid).
Indications
 High risk-mechanism:
◦ High speed motor vehicle collision, bicycle injury, diving or other activity with
hyperextension or hyperflexion of neck, falls greater than body height, and
other acceleration-deceleration injuries of the head.
Multiple system with severe injuries
Distracting pain
Injury above clavicle
Altered mental status
Neck pain, tenderness or limitation of movement
Acute neurological deficit
C-spine xrays
• Coverage
• Alignment
• Disc spaces
• Prevertebral soft tissues
• Edge of image
Anterior vertebral line
Posterior vertebral line
Spinolaminar line
C-spine xrays
• Coverage
• Alignment
• Bone
• Spacing
• Soft tissues
• Edge of image
C-spine xrays
• This view is considered
adequate if it shows the
alignment of the lateral
processes of C1 and C2 (red
circles)
• The distance between the peg
and the lateral masses of C1
(asterisks) should be equal on
each side
Extra views?
If C7/T1 has not been adequately
viewed on the lateral image
Flexion / Extension views
 If Normal plain films AND No neurological deficit AND continued neck pain
AND can actively flex/extend neck for examination.
Efforts to reduce radiation
 A simple decision instrument based on clinical criteria can help
physicians to identify reliably the patients who need radiography of the
cervical spine after blunt trauma. Application of this instrument could
reduce the use of imaging in such patients.
The NEXUS decision instrument performed well in children, and its use
could reduce pediatric cervical spine imaging by nearly 20%. However,
the small number of infants and toddlers in the study suggests caution
in applying the NEXUS criteria to this particular age group.
HOFFMAN ET AL, N ENGL J MED. 2000;343(2):94.
VICCELLIO ET AL, PEDIATRICS. 2001;108(2):E20.
More efforts
CSI in patients younger than 3 years is uncommon. Four simple clinical
predictors can be used in conjunction to the physical examination to
substantially reduce the use of radiographic imaging in this patient
population.
The protocol used has been effective in detecting cervical spine
injuries in noncommunicative children after trauma. The combination of
clinical information and radiographic studies is essential for safely
clearing the cervical spine in these complex situations. Clearance of the
cervical spine without CT or MR imaging studies is possible in the
majority of cases, even in very young patients.
PIERETTI-VANMARCKE ET AL, J TRAUMA. 2009;67(3):543.
ANDERSON ET AL, J NEUROSURG PEDIATR. 2010;5(3):292.
Indications for CT C-spine
Lower or upper C-spines not visualized on plain films
Abnormal or suspicious C-spine on plain films
Suspicion of injury despite normal plain cervical radiographs
As part of initial evaluation of severe head trauma (GCS ≤12) instead of
plain films
CHUNG ET AL, TRAUMA ASSOCIATION OF CANADA PEDIATRIC SUBCOMMITTEE NATIONAL PEDIATRIC CERVICAL
SPINE EVALUATION PATHWAY: CONSENSUS GUIDELINES. J TRAUMA 2011; 70:873.
Indications for MRI
Children with an abnormal neurologic examination and those requiring
imaging of the soft tissues of the spinal column and spinal cord
Patients with normal plain films but persistent concern for neurologic
injury based upon history
Patients with prolonged loss of consciousness in whom cervical spine
cannot be cleared by 24 to 72 hours post injury
CHUNG ET AL, TRAUMA ASSOCIATION OF CANADA PEDIATRIC SUBCOMMITTEE NATIONAL PEDIATRIC CERVICAL
SPINE EVALUATION PATHWAY: CONSENSUS GUIDELINES. J TRAUMA 2011; 70:873.
Real life cases
7 year old girl cheerleader, fell
from 4 meters on the back of her
head and had loss of
consciousness. C/O tingling
sensation at her arms.
Case 2
14 year old involved in a fight and
was hit with a stick to his forhead.
C/O multiple facial fractures
Case 3
11 year old boy on a bicycle not
wearing helmet, smashed a phone
booth and fell with severe orbital
swelling.
Case 4
1 year and 6/12 old girl fell from
2nd floor balcony to the street.
Unwitnessed. Crying from neck
pain.
Take home message
The patient's ability to walk does not exclude cervical spine injury.
Immobilization should be maintained until clearance.
Spinal cord injury can happen without radiological evidence.
Thank you

Pediatric c-spine injuries

  • 1.
    Pediatric cervical injuries AHMADALTHEKAIR, MD CONSULTANT, PEDIATRIC EMERGENCY AND TRAUMA
  • 2.
    Objectives  Epidemiology  Mechanismof injury  Clinical presentation  Approach  Clinical vs. radiological clearance  Current evidence
  • 3.
    Incidence Annually 30-46/1,000,000 Males 60-80% MVCs 35% Falls 25% MVCvs. pedestrian 20% Diving 6% sports 14% LEONARD ET AL, PEDIATRICS VOLUME 133, NUMBER 5, MAY 2014
  • 4.
    Age variation <8 yearsare susceptible to higher cervical injuries (C1-C3) because of: 1. Larger heads than bodies 2. Position of C-spine fulcrum 3. Weaker cervical muscles 4. Increased laxity of ligaments 5. Immature vertebral joints
  • 5.
  • 6.
  • 7.
    Mechanism of injury COURTESYOF ALISON CHANTAL CAVINESS, MD.
  • 8.
    Evaluation Symptoms: ◦ Classic triadof: local pain, muscle spasm, and decreased range of motion of the neck. ◦ Also may complain of transient or persistent paresthesia or weakness. ◦ A retrospective review of 72 previously normal children with cervical spine injury found that all those with asymptomatic injuries had both a high-risk injury mechanism and a distracting injury. ◦ “Burning hand syndrome” “Neck immobilization should be maintained during evaluation and management” BAKER ET A, AM J EMERG MED. 1999;17(3):230.
  • 9.
    Evaluation Physical Examination: ◦ Vitalsigns, Neck exam and Neurologic exam. In toddlers and infants with minor trauma and normal neurological exam; palpate C-spine and assess ROM. If normal, clinically cleared.
  • 10.
    NEXUS criteria 1. Nocervical midline tenderness 2. No focal neurological deficit 3. No intoxication 4. Normal alertness 5. No painful distracting injuries  34,069 trauma victims in 21 nation-wide Emergency departments had 99% sensitivity for C-spine injuries and 99.6% for clinically significant C-spine injuries in adults. HOFFMAN ET AL, N. ENGL. J. MED. 2000;343:94-9
  • 11.
    Limitations in Pediatric 3,065 children were involved, 30 had C-spine injuries.  Sensitivity 100% , Specificity 19.9%.  None of the children studied was younger than 2 years, and only 817 (27%) were younger than age 8 years . PEDIATRICS 2001;108:E20
  • 12.
    Further studies  Single-center,20-year review applied the NEXUS criteria to 190 children with significant cervical spine injury found that the criteria were 94% sensitive among children aged less than 8 years and 100% sensitive in those greater than age 8 years.  A Pediatric Emergency Care Applied Research Network (PECARN) study found that the NEXUS criteria were 83% sensitive among 539 children with spinal injury who presented to the emergency department. Of the 90 children missed by the NEXUS criteria, 58 (64%) were younger than 8 years of age. GARTON ET AL, NEUROSURGERY 2008;62:700-8 LEONARD ET AL, ANN EMERG MED 2011 AUG;58(2):145-55
  • 13.
  • 14.
    Canadian C-spine vs.NEXUS Canadian C-spine NEXUS Sensitivity 99.4% 90.7% P<0.001 Specificity 45.1% 36.8% P<0.001 Radiography rates 55.9% 66.6% P<0.001  The Canadian C-spine Rule would have missed 1 patient and the NEXUS would have missed 16 patients with important injuries.  But, both are not meant for pediatric population. STIELL ET AL, N ENGL J MED 2003; 349:2510-2518
  • 15.
    Trauma Association ofCanada CHUNG ET AL, TRAUMA ASSOCIATION OF CANADA PEDIATRIC SUBCOMMITTEE NATIONAL PEDIATRIC CERVICAL SPINE EVALUATION PATHWAY: CONSENSUS GUIDELINES. J TRAUMA 2011
  • 16.
    Trauma Association ofCanada CHUNG ET AL, TRAUMA ASSOCIATION OF CANADA PEDIATRIC SUBCOMMITTEE NATIONAL PEDIATRIC CERVICAL SPINE EVALUATION PATHWAY: CONSENSUS GUIDELINES. J TRAUMA 2011
  • 17.
    Radiological evaluation  Childrenwith suspected cervical spine injury based on history or physical examination must undergo radiologic evaluation (Cross-table lateral, AP and when obtainable open-mouth odontoid).
  • 18.
    Indications  High risk-mechanism: ◦High speed motor vehicle collision, bicycle injury, diving or other activity with hyperextension or hyperflexion of neck, falls greater than body height, and other acceleration-deceleration injuries of the head. Multiple system with severe injuries Distracting pain Injury above clavicle Altered mental status Neck pain, tenderness or limitation of movement Acute neurological deficit
  • 19.
    C-spine xrays • Coverage •Alignment • Disc spaces • Prevertebral soft tissues • Edge of image Anterior vertebral line Posterior vertebral line Spinolaminar line
  • 20.
    C-spine xrays • Coverage •Alignment • Bone • Spacing • Soft tissues • Edge of image
  • 21.
    C-spine xrays • Thisview is considered adequate if it shows the alignment of the lateral processes of C1 and C2 (red circles) • The distance between the peg and the lateral masses of C1 (asterisks) should be equal on each side
  • 22.
    Extra views? If C7/T1has not been adequately viewed on the lateral image
  • 23.
    Flexion / Extensionviews  If Normal plain films AND No neurological deficit AND continued neck pain AND can actively flex/extend neck for examination.
  • 24.
    Efforts to reduceradiation  A simple decision instrument based on clinical criteria can help physicians to identify reliably the patients who need radiography of the cervical spine after blunt trauma. Application of this instrument could reduce the use of imaging in such patients. The NEXUS decision instrument performed well in children, and its use could reduce pediatric cervical spine imaging by nearly 20%. However, the small number of infants and toddlers in the study suggests caution in applying the NEXUS criteria to this particular age group. HOFFMAN ET AL, N ENGL J MED. 2000;343(2):94. VICCELLIO ET AL, PEDIATRICS. 2001;108(2):E20.
  • 25.
    More efforts CSI inpatients younger than 3 years is uncommon. Four simple clinical predictors can be used in conjunction to the physical examination to substantially reduce the use of radiographic imaging in this patient population. The protocol used has been effective in detecting cervical spine injuries in noncommunicative children after trauma. The combination of clinical information and radiographic studies is essential for safely clearing the cervical spine in these complex situations. Clearance of the cervical spine without CT or MR imaging studies is possible in the majority of cases, even in very young patients. PIERETTI-VANMARCKE ET AL, J TRAUMA. 2009;67(3):543. ANDERSON ET AL, J NEUROSURG PEDIATR. 2010;5(3):292.
  • 26.
    Indications for CTC-spine Lower or upper C-spines not visualized on plain films Abnormal or suspicious C-spine on plain films Suspicion of injury despite normal plain cervical radiographs As part of initial evaluation of severe head trauma (GCS ≤12) instead of plain films CHUNG ET AL, TRAUMA ASSOCIATION OF CANADA PEDIATRIC SUBCOMMITTEE NATIONAL PEDIATRIC CERVICAL SPINE EVALUATION PATHWAY: CONSENSUS GUIDELINES. J TRAUMA 2011; 70:873.
  • 27.
    Indications for MRI Childrenwith an abnormal neurologic examination and those requiring imaging of the soft tissues of the spinal column and spinal cord Patients with normal plain films but persistent concern for neurologic injury based upon history Patients with prolonged loss of consciousness in whom cervical spine cannot be cleared by 24 to 72 hours post injury CHUNG ET AL, TRAUMA ASSOCIATION OF CANADA PEDIATRIC SUBCOMMITTEE NATIONAL PEDIATRIC CERVICAL SPINE EVALUATION PATHWAY: CONSENSUS GUIDELINES. J TRAUMA 2011; 70:873.
  • 28.
    Real life cases 7year old girl cheerleader, fell from 4 meters on the back of her head and had loss of consciousness. C/O tingling sensation at her arms.
  • 29.
    Case 2 14 yearold involved in a fight and was hit with a stick to his forhead. C/O multiple facial fractures
  • 30.
    Case 3 11 yearold boy on a bicycle not wearing helmet, smashed a phone booth and fell with severe orbital swelling.
  • 31.
    Case 4 1 yearand 6/12 old girl fell from 2nd floor balcony to the street. Unwitnessed. Crying from neck pain.
  • 34.
    Take home message Thepatient's ability to walk does not exclude cervical spine injury. Immobilization should be maintained until clearance. Spinal cord injury can happen without radiological evidence.
  • 35.

Editor's Notes

  • #4 Cervical spinal injury (CSI) occurs in about 1% to 1.5% of children evaluated following blunt trauma. The majority of these injuries are in older children; < 5% of CSIs are in children aged < 2 years.
  • #5  The head circumference of a child reaches 50 percent of adult size by two years of age; in contrast, the chest circumference reaches 50 percent of adult size by eight years of age. progresses caudally from C2-3 at birth to C5-6 at eight years of age. greater mobility of the upper cervical spine. horizontally inclined articulating facets that facilitate sliding of the upper cervical spine.
  • #6 Down syndrome (approximately 15 percent have atlantoaxial instability) Morquio syndrome (mucopolysaccharidosis IV), which is associated with hypoplasia of the odontoid Klippel-Feil syndrome (congenital fusion of variable numbers of cervical vertebrae and associated defects including scoliosis, renal anomalies, elevated scapula (Sprengel deformity), congenital heart disease, and deafness) Larsen syndrome, which may have associated cervical vertebrae hypoplasia and is otherwise characterized by multiple joint dislocations, flat facies, and short fingernails.
  • #8 can occur through flexion, extension, vertical compression, rotation, or a combination of these. Most spinal cord injuries result from direct compression or disruption of the cord by fracture fragments or subluxed vertebrae. Hyperflexion injuries are the most common and may cause wedge fractures of the anterior vertebral body with disruption of the posterior elements  Hyperextension injuries may cause compression of the posterior elements and disruption of the anterior longitudinal ligament. An example is the hangman's fracture of the posterior neural arch of C1 or the pedicles of C2 Axial loading may cause burst or comminuted fractures of the arches of C1 in the upper cervical spine or of the vertebral bodies in the lower cervical spine Rotational injuries may cause fracture or dislocation of the facets Chin trauma may provide a clue to cervical spine injury since the force of injury may be transmitted to the jaw and cervical spine.
  • #9 The history should include the presence of symptoms at any time after the injury, even if they have resolved. Transient burning dysesthesias in the hands and fingers may indicate hyperextension of the cervical spine with central cord contusion.
  • #16 Awake, alert, GCS 15 Meet NEXUS criteria and moveflexion, extension and 45 degrees rotation.
  • #17 Unconcious, decreased LOC<15
  • #20 Coverage - All vertebrae are visible from the skull base to the top of T2 (T1 is considered adequate) - If T1 is not visible then a repeat image with the patient's shoulders lowered or a 'swimmer's' view may be necessary Alignment - Check the Anterior line (the line of the anterior longitudinal ligament), the Posterior line (the line of the posterior longitudinal ligament), and the Spinolaminar line (the line formed by the anterior edge of the spinous processes - extends from inner edge of skull) Disc spaces - The vertebral bodies are spaced apart by the intervertebral discs - not directly visible with X-rays. These spaces should be approximately equal in height Pre-vertebral soft tissue - Some fractures cause widening of the pre-vertebral soft tissue due to pre-vertebral haematoma - Normal pre-vertebral soft tissue (asterisks) - narrow down to C4 and wider below - Above C4 ≤ 1/3rd vertebral body width - Below C4 ≤ 100% vertebral body width Note: Not all C-spine fractures are accompanied by pre-vertebral haematoma - lack of pre-vertebral soft tissue thickening should NOT be taken as reassuring Edge of image - Check other visible structures
  • #21 Coverage - The AP view should cover the whole C-spine and the upper thoracic spine Alignment - The lateral edges of the C-spine are aligned (red lines ) Bone - Fractures are often less clearly visible on this view than on the lateral Spacing - The spinous processes (orange) are in a straight line and spaced approximately evenly Soft tissues - Check for surgical emphysema Edges of image - Check for injury to the upper ribs and the lung apices for pneumothorax