Oxygen therapy provides oxygen to tissues through various delivery methods. It is indicated for patients with hypoxemia or critical illness putting them at risk of tissue hypoxia. Low-flow devices like nasal cannulas or face masks deliver oxygen at rates lower than patient demand, mixing it with room air. High-flow devices exceed patient demand to maintain a constant oxygen concentration. Humidification is important to prevent drying of airways from medical gases. Potential complications include carbon dioxide narcosis, atelectasis, oxygen toxicity, and retrolental fibroplasia from extended high oxygen use.