2. Investigating an Outbreak---a Challenge for the Disease Detective 1.What is an outbreak? 2.Uncovering Outbreaks 3.Why Investigate an Outbreak?
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5. Pathogen Mode of Transmission Factors required for the development and maintenance of a disease outbreak Fig.1
6. Mode of Transmission in Acute Outbreak of Disease ★ Person – to – person ★ common-source exposure
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9. Whether an Investigation Is Warranted? ◇ Apparent number of persons affected ◇ Presence of unusual or severe clinical symptoms ◇ Lack of an obvious explanation for disease occurrence ◇ Perceived need to implement control measures ◇ Level of public concern ◇ Potential for contributing to medical knowledge
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15. What interventions could terminate an outbreak? ◆ Removal or elimination of the source of the pathogen ◆ Blockage of the transmission process ◆ Elimination of susceptibility (eg, through vaccination or medication )