OS20 Online 15 December

1. 1EuFMD | Open Session special edition | #OS20se
SEUNG HEON LEE
Center for FMD Vaccine Research, Animal and Plant Quarantine Agency, Republic of Korea
EXPERIMENTAL EVALUATION OF FOOT-
AND-MOUTH DISEASE O SKR VACCINE:
PROTECTIVE EFFICACY AND
SEROLOGICAL PERFORMANCE IN PIGS

2. 2EuFMD | Open Session special edition | #OS20se
• Evaluation of the efficacy of the O SKR 7/10 vaccine by
in vivo challenge test with FMDV O/jincheon/SKR/2014
strain (Mya-98 lineage) in FMD seronegative pigs
MAIN IDEAS
☞ The vaccine belonged to the same O/SEA/Mya-98 lineage as
that of the challenge virus
• Evaluation of the serological performance of the O
SKR 7/10 vaccine in pig farms (field trial)

3. 3EuFMD | Open Session special edition | #OS20se
• The O SKR 7/10 vaccine conferred complete protection in
SPF pigs against homologous challenge, which explained
by the strong serological relationship (r1 ≥ 0.92) between
vaccine and challenge virus
OUTCOMES

4. 4EuFMD | Open Session special edition | #OS20se
• On the other hand, no satisfactory serological elevation
were observed, even in the prime-boost vaccination
groups demonstrating that the vaccine seems to be
somewhat lacking for the field because it dose not
overcome the interference effect of MDA
OUTCOMES

5. eufmdvirtual.com
8, 10, 15, 17 December 2020
EuFMD / Open Session