Orthokeratology Lecture
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Orthokeratology, also known as ortho-k, is a non-surgical alternative to LASIK that uses specially designed contact lenses to reshape the cornea while sleeping. The contact lenses are worn overnight and push the epithelial cells outward to temporarily correct vision without glasses or contacts during the day. Possible side effects include infection which is prevented through proper lens care, and over-correction causing initial blurriness. Ortho-k is suitable for those who want to avoid glasses or contacts, cannot receive LASIK due to age, or want a more affordable option to slow myopia progression.
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Orthokeratology for Controlling Myopia: Clinical Experiences
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After reading the outcomes of the LORIC, CRAYON and SMART studies, two US opticians then undertook their own investigation into whether Overnight Vision Correction (OVC) can slow down or halt the further development of short-sightedness once patients are fitted with overnight ortho-k corrective contact lenses. TOrtho k workshop
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This document provides information about orthokeratology (Ortho-K), a procedure that uses contact lenses to reshape the cornea and reduce or correct myopia. It discusses how Ortho-K works similarly to braces correcting teeth, but the cornea returns to its original shape, so retainer lenses must be worn. Benefits of Ortho-K include being lens-free during the day and potentially slowing myopia progression. Risks and limitations are also outlined. The history and improvements to Ortho-K technology over time are reviewed.
Orthokeratology and Its Effects on Children
This document summarizes the evidence from clinical trials on using orthokeratology (overnight vision correction treatment) to slow the progression of myopia in children. It discusses two key studies, the LORIC study from Hong Kong and the CRAYON study from the US, that found orthokeratology can slow further myopia progression. However, the author notes more research is still needed to provide stronger evidence and ensure the safety of overnight orthokeratology lens wear in children, as it may increase the risk of microbial keratitis. The review then examines two small pilot studies that also found orthokeratology appears to slow myopia progression in children compared to single vision spectacle wear, but controlled trials are still lacking.
Ortho - k lenses by Ashith Tripathi
Orthokeratology, also known as corneal reshaping therapy, uses specially designed contact lenses to temporarily reshape the cornea and reduce or eliminate refractive errors. It allows patients to have clear unaided vision for most of the day by modifying the corneal curvature through overnight lens wear. Studies have shown orthokeratology can slow the progression of myopia in children by an average of 50%. A trial fitting is performed to assess the fluorescein pattern and ensure proper centration, bearing, and tear reservoir before beginning overnight wear to achieve the desired refractive change. Orthokeratology provides an alternative to glasses or surgery and is reversible.
dr Oh's article in Korean CLsociety journal
Orthokeratology has been used since the 1960s to temporarily reshape the cornea and correct refractive errors using rigid gas permeable contact lenses. Its use has grown significantly over the past few decades, especially in Asia where myopia rates have increased rapidly. Recent studies estimate over 1.8 million patients using orthokeratology in China alone. While orthokeratology has been shown to slow myopia progression by 40-60% compared to glasses or soft lenses, researchers aim to develop new customized lens designs and methods that can achieve 100% control of myopia progression by inducing precise peripheral defocus through contact lenses or glasses.
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This document provides an overview of orthokeratology (orthokeratology), which aims to temporarily reshape the cornea through the overnight use of specialized contact lenses to reduce or eliminate the need for refractive correction. It discusses the history of orthokeratology from its origins in the 1960s using conventional geometry lenses to more modern techniques employing reverse geometry lenses made of high Dk materials. The mechanisms by which orthokeratology reshapes the cornea, patient selection criteria, potential indications and contraindications are described. Advantages include reversibility and potentially slowing myopia progression in children, while disadvantages include its non-permanence and risk of non-compliance.
Recommended
Orthokeratology for Controlling Myopia: Clinical Experiences
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Eye care that is new to children, and adults. Find what optometrists are doing that is new using the latest technology in vision care. Freedom from glasses and contacts in the daytime. Look and feel great!
Orthokeratology power point presentation
This document provides information about orthokeratology (Ortho-K), a procedure that uses contact lenses to reshape the cornea and reduce or correct myopia. It discusses how Ortho-K works similarly to braces correcting teeth, but the cornea returns to its original shape, so retainer lenses must be worn. Benefits of Ortho-K include being lens-free during the day and potentially slowing myopia progression. Risks and limitations are also outlined. The history and improvements to Ortho-K technology over time are reviewed.
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Ortho - k lenses by Ashith Tripathi
Orthokeratology, also known as corneal reshaping therapy, uses specially designed contact lenses to temporarily reshape the cornea and reduce or eliminate refractive errors. It allows patients to have clear unaided vision for most of the day by modifying the corneal curvature through overnight lens wear. Studies have shown orthokeratology can slow the progression of myopia in children by an average of 50%. A trial fitting is performed to assess the fluorescein pattern and ensure proper centration, bearing, and tear reservoir before beginning overnight wear to achieve the desired refractive change. Orthokeratology provides an alternative to glasses or surgery and is reversible.
dr Oh's article in Korean CLsociety journal
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Dispensing of ortho k lenses
Orthokeratology uses rigid gas permeable contact lenses worn overnight to temporarily reshape the cornea and reduce or eliminate low to moderate degrees of myopia and astigmatism. The lenses have a molding effect on the cornea through epithelial redistribution, allowing patients to be correction-free during the day. However, the effect is not permanent and vision returns to the pre-treatment level if lenses are not worn. Ortho-k treatment generally takes one month for effects to stabilize and is most effective for prescriptions between -1.00 to -4.50 diopters of myopia and up to -1.50 diopters of astigmatism.
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Cataract,Lasik,Retina,Glaucoma Surgeries at Rushabh Eye Hospital and Laser Ce...
Rated as one of India 's leading Eye Hospitals, Rushabh offers the most advanced Eye Care Treatment and Technology in India today. We also combine the expertise of our team which includes specialist Eye Surgeons who are highly experienced in their specialties of Cataract, Retina, Glaucoma and Laser Eye Surgeries.
Refractive error surgery in india at mumbai and delhi at low cost
Refractive Errors Surgery abroad in India cost Refractive Error surgery India,Refractive Error surgery hospitals India,Refractive eye surgeons India.
Cataract jem
A cataract is a clouding of the normally clear lens of your eye. For people who have cataracts, seeing through cloudy lenses is a bit like looking
Cataract And Presbyopia
This document discusses cataracts and presbyopia, as well as treatment options performed by Dr. Helga Fuenfhausen Pizio. A cataract is a clouding of the eye's lens that causes vision problems and is common in older adults. Symptoms include blurry or faded vision. Surgery is the only treatment and involves removing the clouded lens and replacing it with an artificial lens. For presbyopia, which causes near vision issues, multifocal lenses can provide both near and distance vision after cataract surgery without glasses. Dr. Pizio performs cataract surgery using small incisions and ultrasound and was the first in Nevada to implant a new multifocal lens.
BIONIC EYE
A visual prosthesis, often referred to as a bionic eye, is an experimental visual device intended to restore functional vision in those suffering from partial or total blindness
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Cataract,Lasik,Retina,Glaucoma Surgeries at Rushabh Eye Hospital and Laser Ce...
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Refractive error surgery in india at mumbai and delhi at low cost
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Osvaldo Bernardo Muchanga-GASTROINTESTINAL INFECTIONS AND GASTRITIS-2024.pdf
Osvaldo Bernardo Muchanga-GASTROINTESTINAL INFECTIONS AND GASTRITIS-2024.pdfOsvaldo Bernardo Muchanga
GASTROINTESTINAL INFECTIONS AND GASTRITIS
Osvaldo Bernardo Muchanga
Gastrointestinal Infections
GASTROINTESTINAL INFECTIONS result from the ingestion of pathogens that cause infections at the level of this tract, generally being transmitted by food, water and hands contaminated by microorganisms such as E. coli, Salmonella, Shigella, Vibrio cholerae, Campylobacter, Staphylococcus, Rotavirus among others that are generally contained in feces, thus configuring a FECAL-ORAL type of transmission.
Among the factors that lead to the occurrence of gastrointestinal infections are the hygienic and sanitary deficiencies that characterize our markets and other places where raw or cooked food is sold, poor environmental sanitation in communities, deficiencies in water treatment (or in the process of its plumbing), risky hygienic-sanitary habits (not washing hands after major and/or minor needs), among others.
These are generally consequences (signs and symptoms) resulting from gastrointestinal infections: diarrhea, vomiting, fever and malaise, among others.
The treatment consists of replacing lost liquids and electrolytes (drinking drinking water and other recommended liquids, including consumption of juicy fruits such as papayas, apples, pears, among others that contain water in their composition).
To prevent this, it is necessary to promote health education, improve the hygienic-sanitary conditions of markets and communities in general as a way of promoting, preserving and prolonging PUBLIC HEALTH.
Gastritis and Gastric Health
Gastric Health is one of the most relevant concerns in human health, with gastrointestinal infections being among the main illnesses that affect humans.
Among gastric problems, we have GASTRITIS AND GASTRIC ULCERS as the main public health problems. Gastritis and gastric ulcers normally result from inflammation and corrosion of the walls of the stomach (gastric mucosa) and are generally associated (caused) by the bacterium Helicobacter pylor, which, according to the literature, this bacterium settles on these walls (of the stomach) and starts to release urease that ends up altering the normal pH of the stomach (acid), which leads to inflammation and corrosion of the mucous membranes and consequent gastritis or ulcers, respectively.
In addition to bacterial infections, gastritis and gastric ulcers are associated with several factors, with emphasis on prolonged fasting, chemical substances including drugs, alcohol, foods with strong seasonings including chilli, which ends up causing inflammation of the stomach walls and/or corrosion. of the same, resulting in the appearance of wounds and consequent gastritis or ulcers, respectively.
Among patients with gastritis and/or ulcers, one of the dilemmas is associated with the foods to consume in order to minimize the sensation of pain and discomfort. Nano-gold for Cancer Therapy chemistry investigatory project
chemistry investigatory project
The development of nanogold-based cancer therapy could revolutionize oncology by providing a more targeted, less invasive treatment option. This project contributes to the growing body of research aimed at harnessing nanotechnology for medical applications, paving the way for future clinical trials and potential commercial applications.
Cancer remains one of the leading causes of death worldwide, prompting the need for innovative treatment methods. Nanotechnology offers promising new approaches, including the use of gold nanoparticles (nanogold) for targeted cancer therapy. Nanogold particles possess unique physical and chemical properties that make them suitable for drug delivery, imaging, and photothermal therapy.
Gene Expression System-viral gene delivery Mpharm(Pharamaceutics)
Gene therapy can be broadly defined as the transfer of genetic material to cure a disease or at least to improve the clinical status of a patient.
One of the basic concepts of gene therapy is to transform viruses into genetic shuttles, which will deliver the gene of interest into the target cells.
Safe methods have been devised to do this, using several viral and non-viral vectors.
In the future, this technique may allow doctors to treat a disorder by inserting a gene into a patient's cells instead of using drugs or surgery.
The biggest hurdle faced by medical research in gene therapy is the availability of effective gene-carrying vectors that meet all of the following criteria:
Protection of transgene or genetic cargo from degradative action of systemic and endonucleases,
Delivery of genetic material to the target site, i.e., either cell cytoplasm or nucleus,
Low potential of triggering unwanted immune responses or genotoxicity,
Economical and feasible availability for patients .
Viruses are naturally evolved vehicles that efficiently transfer their genes into host cells.
Choice of viral vector is dependent on gene transfer efficiency, capacity to carry foreign genes, toxicity, stability, immune responses towards viral antigens and potential viral recombination.
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The most common vector system based on retroviruses, adenoviruses, herpes simplex viruses, adeno associated viruses.
Pharmacology of Drugs for Congestive Heart Failure
Congestive Heart failure is caused by low cardiac output and high sympathetic discharge. Diuretics reduce preload, ACE inhibitors lower afterload, beta blockers reduce sympathetic activity, and digitalis has inotropic effects. Newer medications target vasodilation and myosin activation to improve heart efficiency while lowering energy requirements. Combination therapy, following an assessment of cardiac function and volume status, is the most effective strategy to heart failure care.
PGx Analysis in VarSeq: A User’s Perspective
Since our release of the PGx capabilities in VarSeq, we’ve had a few months to gather some insights from various use cases. Some users approach PGx workflows by means of array genotyping or what seems to be a growing trend of adding the star allele calling to the existing NGS pipeline for whole genome data. Luckily, both approaches are supported with the VarSeq software platform. The genotyping method being used will also dictate what the scope of the tertiary analysis will be. For example, are your PGx reports a standalone pipeline or would your lab’s goal be to handle a dual-purpose workflow and report on PGx + Diagnostic findings.
The purpose of this webcast is to:
Discuss and demonstrate the approaches with array and NGS genotyping methods for star allele calling to prep for downstream analysis.
Following genotyping, explore alternative tertiary workflow concepts in VarSeq to handle PGx reporting.
Moreover, we will include insights users will need to consider when validating their PGx workflow for all possible star alleles and options you have for automating your PGx analysis for large number of samples. Please join us for a session dedicated to the application of star allele genotyping and subsequent PGx workflows in our VarSeq software.
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5-hydroxytryptamine or 5-HT or Serotonin is a neurotransmitter that serves a range of roles in the human body. It is sometimes referred to as the happy chemical since it promotes overall well-being and happiness.
It is mostly found in the brain, intestines, and blood platelets.
5-HT is utilised to transport messages between nerve cells, is known to be involved in smooth muscle contraction, and adds to overall well-being and pleasure, among other benefits. 5-HT regulates the body's sleep-wake cycles and internal clock by acting as a precursor to melatonin.
It is hypothesised to regulate hunger, emotions, motor, cognitive, and autonomic processes.
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Giloy in Ayurveda - Classical Categorization and Synonyms
Giloy, also known as Guduchi or Amrita in classical Ayurvedic texts, is a revered herb renowned for its myriad health benefits. It is categorized as a Rasayana, meaning it has rejuvenating properties that enhance vitality and longevity. Giloy is celebrated for its ability to boost the immune system, detoxify the body, and promote overall wellness. Its anti-inflammatory, antipyretic, and antioxidant properties make it a staple in managing conditions like fever, diabetes, and stress. The versatility and efficacy of Giloy in supporting health naturally highlight its importance in Ayurveda. At Planet Ayurveda, we provide a comprehensive range of health services and 100% herbal supplements that harness the power of natural ingredients like Giloy. Our products are globally available and affordable, ensuring that everyone can benefit from the ancient wisdom of Ayurveda. If you or your loved ones are dealing with health issues, contact Planet Ayurveda at 01725214040 to book an online video consultation with our professional doctors. Let us help you achieve optimal health and wellness naturally.
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Public Health Lecture 4 Social Sciences and Public Health
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Orthokeratology Lecture
- 1. orthokeratology LASIK is not the only way
- 2. HISTORY Ancient Chinese thought to sleep with sandbags on the eyes to correct vision Jessen Method introduced in 1962 outlined the fundamental theory. Corneal refractive therapy 2000 became one of the first FDA approved methods for ortho-k
- 3. WHO IS IT FOR? Those want to be free of glasses and contacts Those sensitive to cost of LASIK Emerging presbyopes (~40) Under age 18 (cannot receive LASIK) Progressive myopes
- 4. WHAT HAPPENS? DESIGN SLEEP GO
- 5. A LITTLE DEEPER Epithelial cells are pushed outward shaping the eye Cells will ‘re-migrate’ meaning that ortho-k is not permanent.
- 6. Catch the WAVE Computer aided design Topographer takes over 14K data points on the cornea The software then allows a ‘tailored fit’ contact lens Design is sent electronically to production lab
- 7. SIDE EFFECTS Possible infection: good lens care is important Over-correction. Some blur may occur in the first hours if there the doctor ‘over-prescribes’. This is done frequently to increase the longevity of the effect.
- 8. The bottom line Slows myopic progression Adjustable for emerging presbyopes Frees you from glasses or contacts Non surgical Economical