Ocean Mammals
•Download as PPT, PDF•
0 likes•27 views
Gene sequence of ocean mammals results a ghost gene leaves in it and this genes are responsible for vulnerable to some pesticides.
Report
Share
Report
Share
Recommended
Toxicology
The document provides an overview of toxicology including definitions, sub-disciplines, related terms, mechanisms of toxicity, dose-response relationships, time-effect relationships, classification of toxic agents, factors affecting toxicity, and general management techniques. It also discusses the mechanisms and management of specific toxicities including acetaminophen, benzodiazepines, antidepressants, opiates, and lead poisoning.
Novel antibiotic resistance proteins in V parahaemolyticus
This document describes a study aimed at determining if two genes, emrA and emrB, found in Vibrio parahaemolyticus encode for an efflux pump. V. parahaemolyticus is a pathogenic bacteria that causes food poisoning. Efflux pumps are one mechanism by which bacteria develop antibiotic resistance by actively pumping antibiotics out of the cell. The genes were cloned into an expression vector and introduced into E. coli. Minimum inhibitory concentration assays were performed using four different antibiotics on the transformed E. coli to test the ability of the genes to confer antibiotic resistance, which would suggest they encode for an efflux pump. The results were inconclusive but further research may determine if the genes do encode for an eff
our paper
This document summarizes a study that investigated the effects of o-phenylenediamine (oPD) exposure on biochemical parameters in the liver and brain of zebrafish. Zebrafish were exposed to 1ppm and 5ppm of oPD for 15 days. Biological oxygen demand tests found moderate pollution in water treated with both concentrations of oPD. Exposure resulted in increased liver oxidative stress and alterations in liver detoxification enzymes and brain monoamine oxidase activity, suggesting oPD toxicity affects multiple organ systems. The study aims to understand the chronic effects and toxicity mechanism of oPD in aquatic animals like zebrafish.
Aflatoxins -biochemistry_and_molecular_biology
This chapter discusses the biotransformation of aflatoxin B1 (AFB1) and its relationship to the differential toxicological response in commercial poultry species. AFB1 is highly toxic to most animal species, though some are more susceptible than others. The toxic effects of AFB1 are dose- and time-dependent, and can cause acute or chronic aflatoxicosis. While AFB1 exposure primarily damages the liver in poultry, different species vary in their sensitivity, from most sensitive (ducklings) to less sensitive (chickens). Differences in biotransformation of AFB1, specifically variations in cytochrome P450-mediated metabolism, may contribute to this differential toxicity between p
aflatoxinas
This chapter discusses the biotransformation of aflatoxin B1 (AFB1) and its relationship to the differential toxicological response in commercial poultry species. AFB1 is highly toxic to most animal species, though some are more susceptible than others. The toxic effects of AFB1 are dose- and time-dependent, and can cause acute or chronic aflatoxicosis. While AFB1 exposure primarily damages the liver in poultry, different species vary in their sensitivity, from most sensitive (ducklings) to less sensitive (chickens). Differences in biotransformation of AFB1, specifically variations in cytochrome P450-mediated metabolism, may contribute to this differential toxicity between p
Organophosphorous poisoning
Organophosphorus (OP) compounds are a large family of chemicals that are widely used as pesticides and were developed as nerve agents. Exposure to OPs can cause acute poisoning by inhibiting acetylcholinesterase and overstimulating the parasympathetic nervous system. This can result in muscle weakness, seizures, respiratory failure and death. Several cases of accidental and intentional OP poisoning in India are described, including an incident where school children were poisoned by contaminated food, resulting in many deaths. Chronic low-level exposure to OP pesticides also poses health risks and is a major cause of poisoning in developing nations.
Fluorescent probes
Fluorescent probes are single fluorophores or fluorophores covalently conjugated with biological molecules. Several types of fluorescent probes are provided on BOC Sciences website.
Recommended
Toxicology
The document provides an overview of toxicology including definitions, sub-disciplines, related terms, mechanisms of toxicity, dose-response relationships, time-effect relationships, classification of toxic agents, factors affecting toxicity, and general management techniques. It also discusses the mechanisms and management of specific toxicities including acetaminophen, benzodiazepines, antidepressants, opiates, and lead poisoning.
Novel antibiotic resistance proteins in V parahaemolyticus
This document describes a study aimed at determining if two genes, emrA and emrB, found in Vibrio parahaemolyticus encode for an efflux pump. V. parahaemolyticus is a pathogenic bacteria that causes food poisoning. Efflux pumps are one mechanism by which bacteria develop antibiotic resistance by actively pumping antibiotics out of the cell. The genes were cloned into an expression vector and introduced into E. coli. Minimum inhibitory concentration assays were performed using four different antibiotics on the transformed E. coli to test the ability of the genes to confer antibiotic resistance, which would suggest they encode for an efflux pump. The results were inconclusive but further research may determine if the genes do encode for an eff
our paper
This document summarizes a study that investigated the effects of o-phenylenediamine (oPD) exposure on biochemical parameters in the liver and brain of zebrafish. Zebrafish were exposed to 1ppm and 5ppm of oPD for 15 days. Biological oxygen demand tests found moderate pollution in water treated with both concentrations of oPD. Exposure resulted in increased liver oxidative stress and alterations in liver detoxification enzymes and brain monoamine oxidase activity, suggesting oPD toxicity affects multiple organ systems. The study aims to understand the chronic effects and toxicity mechanism of oPD in aquatic animals like zebrafish.
Aflatoxins -biochemistry_and_molecular_biology
This chapter discusses the biotransformation of aflatoxin B1 (AFB1) and its relationship to the differential toxicological response in commercial poultry species. AFB1 is highly toxic to most animal species, though some are more susceptible than others. The toxic effects of AFB1 are dose- and time-dependent, and can cause acute or chronic aflatoxicosis. While AFB1 exposure primarily damages the liver in poultry, different species vary in their sensitivity, from most sensitive (ducklings) to less sensitive (chickens). Differences in biotransformation of AFB1, specifically variations in cytochrome P450-mediated metabolism, may contribute to this differential toxicity between p
aflatoxinas
This chapter discusses the biotransformation of aflatoxin B1 (AFB1) and its relationship to the differential toxicological response in commercial poultry species. AFB1 is highly toxic to most animal species, though some are more susceptible than others. The toxic effects of AFB1 are dose- and time-dependent, and can cause acute or chronic aflatoxicosis. While AFB1 exposure primarily damages the liver in poultry, different species vary in their sensitivity, from most sensitive (ducklings) to less sensitive (chickens). Differences in biotransformation of AFB1, specifically variations in cytochrome P450-mediated metabolism, may contribute to this differential toxicity between p
Organophosphorous poisoning
Organophosphorus (OP) compounds are a large family of chemicals that are widely used as pesticides and were developed as nerve agents. Exposure to OPs can cause acute poisoning by inhibiting acetylcholinesterase and overstimulating the parasympathetic nervous system. This can result in muscle weakness, seizures, respiratory failure and death. Several cases of accidental and intentional OP poisoning in India are described, including an incident where school children were poisoned by contaminated food, resulting in many deaths. Chronic low-level exposure to OP pesticides also poses health risks and is a major cause of poisoning in developing nations.
Fluorescent probes
Fluorescent probes are single fluorophores or fluorophores covalently conjugated with biological molecules. Several types of fluorescent probes are provided on BOC Sciences website.
Toxicity of Pesticides
This document discusses toxicity from pesticides, specifically organophosphates and paraquat. It provides information on:
1) Organophosphates are commonly found in household and agricultural pesticides as well as some medical treatments. They work by inhibiting cholinesterase enzymes, leading to excess acetylcholine and symptoms like muscle fasciculations, weakness, and seizures.
2) Paraquat is a herbicide that is toxic when ingested, with a lethal dose between 1-4 grams. It causes lung damage through redox cycling and production of reactive oxygen species.
3) Clinical manifestations of organophosphate toxicity include muscarinic effects like increased salivation as well as nicotinic effects
QUINALPHOS INDUCED BIOCHEMICAL AND PATHOPHYSIOLOGICAL CHANGES IN FRESHWATER E...
This document discusses a study on the biochemical and pathophysiological changes in the freshwater fish Cyprinus carpio exposed to the organophosphate pesticide quinalphos. The study aims to understand the toxic effects of lethal and sublethal concentrations of quinalphos on C. carpio over different exposure periods. Biochemical parameters like proteins, oxidative stress markers, acetylcholinesterase activity, ions, and ATPases will be analyzed in the gills, kidney, and liver tissues of exposed fish. Histopathological changes and accumulation of the pesticide will also be examined in these tissues. The results will provide insights into the toxic impacts of quinalphos exposure on C. carpio at biochemical
1.pdf
Five bacterial strains capable of degrading polycyclic aromatic hydrocarbons (PAHs) like phenanthrene, anthracene, and pyrene were isolated from an activated sludge wastewater treatment plant. The isolates were identified as Sphingopyxis ummariensis through 16S rRNA gene sequencing. Batch experiments showed the isolates could utilize the PAHs as their sole carbon and energy source. A first-order kinetic model fit the phenanthrene degradation profiles well. Rate constants for phenanthrene degradation ranged from 0.653 to 0.878 day-1, with half-lives of 0.79 to 1.06 days. The isolates showed preference for degrading phenanthrene over anthracene
Aqtox3067.pdf.l644g84
This document is a research article that examines the effects of the pesticide carbofuran on the early life stages of Nile tilapia (Oreochromis niloticus). The article describes experiments exposing tilapia larvae to various concentrations of carbofuran to determine mortality rates, effects on cholinesterase enzyme activity, and impacts on behaviors like vision, swimming, prey capture, and response to predators. The results showed sublethal carbofuran exposure can inhibit cholinesterase activity, impair vision and reduce swimming speed, prey capture attempts, growth, and ability to avoid predators in tilapia larvae.
Classification of Insecticide ppppot.pptx
This document discusses the classification of insecticides. It can be classified in several ways:
1. By chemical composition - inorganic (arsenic, fluorine) and organic (plant-derived like pyrethrins or synthetic like DDT and organophosphates).
2. By mode of entry - contact poisons, stomach poisons, fumigants, and systemic insecticides.
3. By mode of action - physical poisons, protoplasmic poisons, respiratory poisons, nerve poisons, and chitin inhibition.
4. By toxicity - extremely toxic, moderately toxic, highly toxic, and less toxic.
5. By stage specificity - ovicides, larvicides
Phytotoxin
Phytotoxin
phtotoxin produce by bacteria and fungi
Bacterial toxin are two types endotoxin and exotoxins
Fungi produce toxin Mycotoxins
Mycotoxins - Aflatoxins B1, B2, G1, G2,
Products contaminated by aflatoxins such as cereal, tree nuts, dry fruits, spices, dairy products, eggs, and medicinal plants.
There are various methods use for the detections of aflatoxins like HPLC, HPTLC, ELISA,TLC, and LC-MS.
Aflatoxins cause chronic and acute toxicity.
Chronic- slow growth, immunity problems, cirrhosis, and liver cancer.
Acute- Hemorrhage, edema and acute liver toxicity.
Or4d11 Olfactory Receptors
The document discusses olfactory receptors and compares the olfactory receptor gene OR4D11 between humans and chimpanzees. It finds that OR4D11 is a pseudogene in humans but intact in chimpanzees. It also summarizes the results of BLAST searches comparing the human and chimpanzee OR4D11 sequences and structures, finding them to be 96% similar. Phylogenetic analysis shows OR4D11 is conserved in other species like mice, dogs, and rats.
95.full
1) The olsA gene mediates the synthesis of ornithine lipids in P. aeruginosa under phosphate-limiting conditions. Ornithine lipids are phosphate-free and their production allows the bacteria to reduce phosphate utilization in its membranes.
2) Mass spectrometry analysis confirmed the production and structure of ornithine lipids in P. aeruginosa, which contain mainly C16:0 and C18:1 fatty acid chains.
3) While resistance to antimicrobial peptides increases under phosphate limitation, ornithine lipid production was found to not be required for this increased resistance or for virulence in a C. elegans infection model.
ausama PP.PDF
The study evaluated the long-term effects of administering silibinin, epigallocatechin, quercetin, or rutin on the absorption and tissue distribution of zinc, copper, and iron in rats. The results showed that all flavonoids increased serum and tissue levels of the trace elements compared to controls. Specifically, the flavonoids increased absorption of all three elements and their availability in brain, kidney, and liver tissues. However, the effects varied between flavonoids, with epigallocatechin generally having the greatest effect on iron absorption and tissue levels. The study suggests long-term intake of high-dose flavonoid supplements could increase absorption and tissue accumulation of some trace elements.
Presentation of antioxidant activity of marine bioactive compounds
Marine organisms are rich sources of bioactive compounds with antioxidant properties. This study analyzed the antioxidant activity of compounds extracted from marine bioresources such as algae, fungi, bacteria, and invertebrates. Phenolic compounds, carotenoids, and anthraquinones with antioxidant effects were isolated from marine fungi using solvent extraction. The extracts were tested for antioxidant activity using methods like DPPH radical scavenging and reducing power assays. Compounds with potential antioxidant properties were identified that could serve as natural antioxidants or lead to new drugs.
FUNGICIDE RESIDUE AND HEALTH HAZARDS.pptx
This document discusses the health hazards of fungicide residues. It begins by defining fungicides and fungicide residues. It then discusses how pesticide residues occur in agriculture and related terms like persistence and deposit. It outlines some maximum residue limits set by India and the Codex Alimentarius. It details several toxic effects of pesticide residues on human health like neuronal damage, long-term neuropsychiatric disorders, persistent memory and cognitive deficits, psychomotor performance deficits, oxidative stress, cancer development, and reproductive disorders.
Current Research, Technology Bioluminescent
This document discusses the isolation and characterization of bioluminescent bacteria from marine environments in Puerto Rico. 125 pure isolates of bioluminescent bacteria were obtained using general microbiological techniques. The isolates are undergoing molecular analysis including 16S rRNA gene sequencing to identify the bacteria and amplification of the lux genes responsible for bioluminescence. The goals are to report on the diversity of bioluminescent bacteria found in Puerto Rico's marine environments and evaluate the potential of the isolates as biosensors to detect water contaminants.
THESIS_APRIL2015_0501_Final
This thesis studied the metabolic pathways altered in Pseudomonas fluorescens Pf-5 due to hexavalent chromium stress using NMR-based metabolomics. P. fluorescens was exposed to 50 ppm of chromium for 6 and 24 hours. Metabolite extracts were analyzed using NMR and principal component analysis showed distinct metabolic profiles between control and stressed cells. Further analysis identified significant metabolites and probable pathways impacted by chromium stress.
Two research articles on pesticides in cambodia 2011 02 28 vs 07 2011
Brief discussion of the implication of two articles concerning pesticide use in vegetable production in Cambodia and effects on pesticide resiues in market vegetables.
screening model for Parkinson's disease.pptx
Parkinson's disease (PD) is a complex neurodegenerative disorder characterized by the progressive degeneration of dopaminergic neurons in the substantia nigra region of the brain. This degeneration results in a wide range of motor and non-motor symptoms, including bradykinesia, rigidity, tremors, and postural instability. PD not only affects motor function but also leads to cognitive and psychiatric impairments, significantly reducing the quality of life for those afflicted.
1) The first abstract suggest that predator prey relationship outc.pdf
1) The first abstract suggest that predator / prey relationship outcome of P.fiesteria and
rhodomonas is determined by presence and absence of specific bacterium that is a alpha-
proteobacterium which have sequence similarity with roseobactor species present in toxic
dianoflagellete species. In the presence of this bacterial isolate consumption of rhodomonas is
increase that ultimately leads to the growth of Pfiesteria. Molecular analysis of ameboied stages
of toxic culture of clonal P. fiesteria species by verious research group suggested that P. fiesteria
species differe in response to fresh fish mucus, algal prey and inorganic nutrient enrichment
depending on funtional type or toxicity status. There are three functional type of P. fiesteria
ToxA, ToxB, NonIND depending upon their toxicity in the presence of fish, zoospore production
and attraction to fish excreta and mucus. So, this study suggest that Non IND strain should not
used for research about environment control on toxic strain of P fiesteria species.
Right environment condition (overencrichment of nutrient (N&P) - P. fiesteria exposed to large
number of finfish- increase toxin production- distroy fish epidermis- once fish dead- reduce its
toxin production- feeds on the fish either as zoospores or other forms
Whenenvironment condition change- finfish few or low in number - P.fiesteria become nontoxic
or dormant
P. fiesteria also effect people learning and reading capacity and couse other symptoms who are
very close to the contaminated water such as fishermen.
P. fiesteria growth is controlled by temperature and water quality.
3) Production of toxin, toxic activity and attraction to fresh fish tissue and excreta are the
responsed that activated by signal in variably toxic strains of P.fiesteria.
4) inorganic nutrient enrichment, presence of fresh fish and algal prey cause the development of
three strains
5) development of toxicity in Pfiesteria is caused by presence of fresh fish tissue and excreta and
its couse death of live fish. ToxA cause maximum killing have strong attraction to live fish
whereas Tox B has intermediate effect, and Non IND has negligible effect becouse have low
attraction to fresh fish and maximum zoospore production capacity.
2) THE symbiotic relationship of bacteria with Pfiesteria control its growth and consumption of
rhodomonas so to increase consumption of itself P.fiesteria adopt a colonization with bacteria.
Solution
1) The first abstract suggest that predator / prey relationship outcome of P.fiesteria and
rhodomonas is determined by presence and absence of specific bacterium that is a alpha-
proteobacterium which have sequence similarity with roseobactor species present in toxic
dianoflagellete species. In the presence of this bacterial isolate consumption of rhodomonas is
increase that ultimately leads to the growth of Pfiesteria. Molecular analysis of ameboied stages
of toxic culture of clonal P. fiesteria species by verious research group suggested th.
Aflatoxin
Mycotoxins are toxic metabolites produced by fungi that can contaminate foods. They are classified into six major types including aflatoxins, ochratoxin A, patulin, fumonisins, deoxynivalenol, and zearalenone. Aflatoxins are the most studied mycotoxins and are produced by Aspergillus species of fungi. They are carcinogenic and pose health risks such as liver cancer. Preventing pre-harvest and post-harvest contamination is important to reduce human exposure to these toxic fungal metabolites in food.
Aflatoxin.pdf
Mycotoxins are toxic metabolites produced by fungi that can contaminate foods. Major mycotoxins include aflatoxins, ochratoxin A, patulin, fumonisins, deoxynivalenol, and zearalenone. Aflatoxins are produced by Aspergillus species and pose health risks as they are carcinogenic and can cause acute toxicity in humans and animals. Regulatory bodies set maximum limits for mycotoxins in foods and feeds.
Presentation3
This document discusses the development of transgenic zebrafish as biosensors to detect acid pollution in Minnesota waters. Researchers injected zebrafish with a vector containing GPI-GFP and a blue heart gene, resulting in fluorescent expression localized to tissues. They are currently sequencing the GPI-SEP vector to create a potential pH-sensitive biosensor fish. Two additional biosensor fish lines were added to the library. The ongoing work involves further developing the pH-sensitive fish and testing it and other biosensors against Minnesota pollutants to expand the library of tools for assessing environmental quality in classrooms.
Pharmaceuticals in the aquatic environment and their effects in fish
Name: Viktoriia Burkina
Title of thesis: Pharmaceuticals in the aquatic environment and their effects in fish.
Tesis doctoral, acerca del efecto de fármacos en el pez Oncorhynchus mykiss, incluye la interacción y publicaciones realizadas.
THEMATIC APPERCEPTION TEST(TAT) cognitive abilities, creativity, and critic...
THEMATIC APPERCEPTION TEST(TAT) cognitive abilities, creativity, and critic...Abdul Wali Khan University Mardan,kP,Pakistan
hematic appreciation test is a psychological assessment tool used to measure an individual's appreciation and understanding of specific themes or topics. This test helps to evaluate an individual's ability to connect different ideas and concepts within a given theme, as well as their overall comprehension and interpretation skills. The results of the test can provide valuable insights into an individual's cognitive abilities, creativity, and critical thinking skillsMore Related Content
Similar to Ocean Mammals
Toxicity of Pesticides
This document discusses toxicity from pesticides, specifically organophosphates and paraquat. It provides information on:
1) Organophosphates are commonly found in household and agricultural pesticides as well as some medical treatments. They work by inhibiting cholinesterase enzymes, leading to excess acetylcholine and symptoms like muscle fasciculations, weakness, and seizures.
2) Paraquat is a herbicide that is toxic when ingested, with a lethal dose between 1-4 grams. It causes lung damage through redox cycling and production of reactive oxygen species.
3) Clinical manifestations of organophosphate toxicity include muscarinic effects like increased salivation as well as nicotinic effects
QUINALPHOS INDUCED BIOCHEMICAL AND PATHOPHYSIOLOGICAL CHANGES IN FRESHWATER E...
This document discusses a study on the biochemical and pathophysiological changes in the freshwater fish Cyprinus carpio exposed to the organophosphate pesticide quinalphos. The study aims to understand the toxic effects of lethal and sublethal concentrations of quinalphos on C. carpio over different exposure periods. Biochemical parameters like proteins, oxidative stress markers, acetylcholinesterase activity, ions, and ATPases will be analyzed in the gills, kidney, and liver tissues of exposed fish. Histopathological changes and accumulation of the pesticide will also be examined in these tissues. The results will provide insights into the toxic impacts of quinalphos exposure on C. carpio at biochemical
1.pdf
Five bacterial strains capable of degrading polycyclic aromatic hydrocarbons (PAHs) like phenanthrene, anthracene, and pyrene were isolated from an activated sludge wastewater treatment plant. The isolates were identified as Sphingopyxis ummariensis through 16S rRNA gene sequencing. Batch experiments showed the isolates could utilize the PAHs as their sole carbon and energy source. A first-order kinetic model fit the phenanthrene degradation profiles well. Rate constants for phenanthrene degradation ranged from 0.653 to 0.878 day-1, with half-lives of 0.79 to 1.06 days. The isolates showed preference for degrading phenanthrene over anthracene
Aqtox3067.pdf.l644g84
This document is a research article that examines the effects of the pesticide carbofuran on the early life stages of Nile tilapia (Oreochromis niloticus). The article describes experiments exposing tilapia larvae to various concentrations of carbofuran to determine mortality rates, effects on cholinesterase enzyme activity, and impacts on behaviors like vision, swimming, prey capture, and response to predators. The results showed sublethal carbofuran exposure can inhibit cholinesterase activity, impair vision and reduce swimming speed, prey capture attempts, growth, and ability to avoid predators in tilapia larvae.
Classification of Insecticide ppppot.pptx
This document discusses the classification of insecticides. It can be classified in several ways:
1. By chemical composition - inorganic (arsenic, fluorine) and organic (plant-derived like pyrethrins or synthetic like DDT and organophosphates).
2. By mode of entry - contact poisons, stomach poisons, fumigants, and systemic insecticides.
3. By mode of action - physical poisons, protoplasmic poisons, respiratory poisons, nerve poisons, and chitin inhibition.
4. By toxicity - extremely toxic, moderately toxic, highly toxic, and less toxic.
5. By stage specificity - ovicides, larvicides
Phytotoxin
Phytotoxin
phtotoxin produce by bacteria and fungi
Bacterial toxin are two types endotoxin and exotoxins
Fungi produce toxin Mycotoxins
Mycotoxins - Aflatoxins B1, B2, G1, G2,
Products contaminated by aflatoxins such as cereal, tree nuts, dry fruits, spices, dairy products, eggs, and medicinal plants.
There are various methods use for the detections of aflatoxins like HPLC, HPTLC, ELISA,TLC, and LC-MS.
Aflatoxins cause chronic and acute toxicity.
Chronic- slow growth, immunity problems, cirrhosis, and liver cancer.
Acute- Hemorrhage, edema and acute liver toxicity.
Or4d11 Olfactory Receptors
The document discusses olfactory receptors and compares the olfactory receptor gene OR4D11 between humans and chimpanzees. It finds that OR4D11 is a pseudogene in humans but intact in chimpanzees. It also summarizes the results of BLAST searches comparing the human and chimpanzee OR4D11 sequences and structures, finding them to be 96% similar. Phylogenetic analysis shows OR4D11 is conserved in other species like mice, dogs, and rats.
95.full
1) The olsA gene mediates the synthesis of ornithine lipids in P. aeruginosa under phosphate-limiting conditions. Ornithine lipids are phosphate-free and their production allows the bacteria to reduce phosphate utilization in its membranes.
2) Mass spectrometry analysis confirmed the production and structure of ornithine lipids in P. aeruginosa, which contain mainly C16:0 and C18:1 fatty acid chains.
3) While resistance to antimicrobial peptides increases under phosphate limitation, ornithine lipid production was found to not be required for this increased resistance or for virulence in a C. elegans infection model.
ausama PP.PDF
The study evaluated the long-term effects of administering silibinin, epigallocatechin, quercetin, or rutin on the absorption and tissue distribution of zinc, copper, and iron in rats. The results showed that all flavonoids increased serum and tissue levels of the trace elements compared to controls. Specifically, the flavonoids increased absorption of all three elements and their availability in brain, kidney, and liver tissues. However, the effects varied between flavonoids, with epigallocatechin generally having the greatest effect on iron absorption and tissue levels. The study suggests long-term intake of high-dose flavonoid supplements could increase absorption and tissue accumulation of some trace elements.
Presentation of antioxidant activity of marine bioactive compounds
Marine organisms are rich sources of bioactive compounds with antioxidant properties. This study analyzed the antioxidant activity of compounds extracted from marine bioresources such as algae, fungi, bacteria, and invertebrates. Phenolic compounds, carotenoids, and anthraquinones with antioxidant effects were isolated from marine fungi using solvent extraction. The extracts were tested for antioxidant activity using methods like DPPH radical scavenging and reducing power assays. Compounds with potential antioxidant properties were identified that could serve as natural antioxidants or lead to new drugs.
FUNGICIDE RESIDUE AND HEALTH HAZARDS.pptx
This document discusses the health hazards of fungicide residues. It begins by defining fungicides and fungicide residues. It then discusses how pesticide residues occur in agriculture and related terms like persistence and deposit. It outlines some maximum residue limits set by India and the Codex Alimentarius. It details several toxic effects of pesticide residues on human health like neuronal damage, long-term neuropsychiatric disorders, persistent memory and cognitive deficits, psychomotor performance deficits, oxidative stress, cancer development, and reproductive disorders.
Current Research, Technology Bioluminescent
This document discusses the isolation and characterization of bioluminescent bacteria from marine environments in Puerto Rico. 125 pure isolates of bioluminescent bacteria were obtained using general microbiological techniques. The isolates are undergoing molecular analysis including 16S rRNA gene sequencing to identify the bacteria and amplification of the lux genes responsible for bioluminescence. The goals are to report on the diversity of bioluminescent bacteria found in Puerto Rico's marine environments and evaluate the potential of the isolates as biosensors to detect water contaminants.
THESIS_APRIL2015_0501_Final
This thesis studied the metabolic pathways altered in Pseudomonas fluorescens Pf-5 due to hexavalent chromium stress using NMR-based metabolomics. P. fluorescens was exposed to 50 ppm of chromium for 6 and 24 hours. Metabolite extracts were analyzed using NMR and principal component analysis showed distinct metabolic profiles between control and stressed cells. Further analysis identified significant metabolites and probable pathways impacted by chromium stress.
Two research articles on pesticides in cambodia 2011 02 28 vs 07 2011
Brief discussion of the implication of two articles concerning pesticide use in vegetable production in Cambodia and effects on pesticide resiues in market vegetables.
screening model for Parkinson's disease.pptx
Parkinson's disease (PD) is a complex neurodegenerative disorder characterized by the progressive degeneration of dopaminergic neurons in the substantia nigra region of the brain. This degeneration results in a wide range of motor and non-motor symptoms, including bradykinesia, rigidity, tremors, and postural instability. PD not only affects motor function but also leads to cognitive and psychiatric impairments, significantly reducing the quality of life for those afflicted.
1) The first abstract suggest that predator prey relationship outc.pdf
1) The first abstract suggest that predator / prey relationship outcome of P.fiesteria and
rhodomonas is determined by presence and absence of specific bacterium that is a alpha-
proteobacterium which have sequence similarity with roseobactor species present in toxic
dianoflagellete species. In the presence of this bacterial isolate consumption of rhodomonas is
increase that ultimately leads to the growth of Pfiesteria. Molecular analysis of ameboied stages
of toxic culture of clonal P. fiesteria species by verious research group suggested that P. fiesteria
species differe in response to fresh fish mucus, algal prey and inorganic nutrient enrichment
depending on funtional type or toxicity status. There are three functional type of P. fiesteria
ToxA, ToxB, NonIND depending upon their toxicity in the presence of fish, zoospore production
and attraction to fish excreta and mucus. So, this study suggest that Non IND strain should not
used for research about environment control on toxic strain of P fiesteria species.
Right environment condition (overencrichment of nutrient (N&P) - P. fiesteria exposed to large
number of finfish- increase toxin production- distroy fish epidermis- once fish dead- reduce its
toxin production- feeds on the fish either as zoospores or other forms
Whenenvironment condition change- finfish few or low in number - P.fiesteria become nontoxic
or dormant
P. fiesteria also effect people learning and reading capacity and couse other symptoms who are
very close to the contaminated water such as fishermen.
P. fiesteria growth is controlled by temperature and water quality.
3) Production of toxin, toxic activity and attraction to fresh fish tissue and excreta are the
responsed that activated by signal in variably toxic strains of P.fiesteria.
4) inorganic nutrient enrichment, presence of fresh fish and algal prey cause the development of
three strains
5) development of toxicity in Pfiesteria is caused by presence of fresh fish tissue and excreta and
its couse death of live fish. ToxA cause maximum killing have strong attraction to live fish
whereas Tox B has intermediate effect, and Non IND has negligible effect becouse have low
attraction to fresh fish and maximum zoospore production capacity.
2) THE symbiotic relationship of bacteria with Pfiesteria control its growth and consumption of
rhodomonas so to increase consumption of itself P.fiesteria adopt a colonization with bacteria.
Solution
1) The first abstract suggest that predator / prey relationship outcome of P.fiesteria and
rhodomonas is determined by presence and absence of specific bacterium that is a alpha-
proteobacterium which have sequence similarity with roseobactor species present in toxic
dianoflagellete species. In the presence of this bacterial isolate consumption of rhodomonas is
increase that ultimately leads to the growth of Pfiesteria. Molecular analysis of ameboied stages
of toxic culture of clonal P. fiesteria species by verious research group suggested th.
Aflatoxin
Mycotoxins are toxic metabolites produced by fungi that can contaminate foods. They are classified into six major types including aflatoxins, ochratoxin A, patulin, fumonisins, deoxynivalenol, and zearalenone. Aflatoxins are the most studied mycotoxins and are produced by Aspergillus species of fungi. They are carcinogenic and pose health risks such as liver cancer. Preventing pre-harvest and post-harvest contamination is important to reduce human exposure to these toxic fungal metabolites in food.
Aflatoxin.pdf
Mycotoxins are toxic metabolites produced by fungi that can contaminate foods. Major mycotoxins include aflatoxins, ochratoxin A, patulin, fumonisins, deoxynivalenol, and zearalenone. Aflatoxins are produced by Aspergillus species and pose health risks as they are carcinogenic and can cause acute toxicity in humans and animals. Regulatory bodies set maximum limits for mycotoxins in foods and feeds.
Presentation3
This document discusses the development of transgenic zebrafish as biosensors to detect acid pollution in Minnesota waters. Researchers injected zebrafish with a vector containing GPI-GFP and a blue heart gene, resulting in fluorescent expression localized to tissues. They are currently sequencing the GPI-SEP vector to create a potential pH-sensitive biosensor fish. Two additional biosensor fish lines were added to the library. The ongoing work involves further developing the pH-sensitive fish and testing it and other biosensors against Minnesota pollutants to expand the library of tools for assessing environmental quality in classrooms.
Pharmaceuticals in the aquatic environment and their effects in fish
Name: Viktoriia Burkina
Title of thesis: Pharmaceuticals in the aquatic environment and their effects in fish.
Tesis doctoral, acerca del efecto de fármacos en el pez Oncorhynchus mykiss, incluye la interacción y publicaciones realizadas.
Similar to Ocean Mammals (20)
QUINALPHOS INDUCED BIOCHEMICAL AND PATHOPHYSIOLOGICAL CHANGES IN FRESHWATER E...
QUINALPHOS INDUCED BIOCHEMICAL AND PATHOPHYSIOLOGICAL CHANGES IN FRESHWATER E...
Presentation of antioxidant activity of marine bioactive compounds
Presentation of antioxidant activity of marine bioactive compounds
Two research articles on pesticides in cambodia 2011 02 28 vs 07 2011
Two research articles on pesticides in cambodia 2011 02 28 vs 07 2011
1) The first abstract suggest that predator prey relationship outc.pdf
1) The first abstract suggest that predator prey relationship outc.pdf
Pharmaceuticals in the aquatic environment and their effects in fish
Pharmaceuticals in the aquatic environment and their effects in fish
Recently uploaded
THEMATIC APPERCEPTION TEST(TAT) cognitive abilities, creativity, and critic...
THEMATIC APPERCEPTION TEST(TAT) cognitive abilities, creativity, and critic...Abdul Wali Khan University Mardan,kP,Pakistan
hematic appreciation test is a psychological assessment tool used to measure an individual's appreciation and understanding of specific themes or topics. This test helps to evaluate an individual's ability to connect different ideas and concepts within a given theme, as well as their overall comprehension and interpretation skills. The results of the test can provide valuable insights into an individual's cognitive abilities, creativity, and critical thinking skillsPhenomics assisted breeding in crop improvement
As the population is increasing and will reach about 9 billion upto 2050. Also due to climate change, it is difficult to meet the food requirement of such a large population. Facing the challenges presented by resource shortages, climate
change, and increasing global population, crop yield and quality need to be improved in a sustainable way over the coming decades. Genetic improvement by breeding is the best way to increase crop productivity. With the rapid progression of functional
genomics, an increasing number of crop genomes have been sequenced and dozens of genes influencing key agronomic traits have been identified. However, current genome sequence information has not been adequately exploited for understanding
the complex characteristics of multiple gene, owing to a lack of crop phenotypic data. Efficient, automatic, and accurate technologies and platforms that can capture phenotypic data that can
be linked to genomics information for crop improvement at all growth stages have become as important as genotyping. Thus,
high-throughput phenotyping has become the major bottleneck restricting crop breeding. Plant phenomics has been defined as the high-throughput, accurate acquisition and analysis of multi-dimensional phenotypes
during crop growing stages at the organism level, including the cell, tissue, organ, individual plant, plot, and field levels. With the rapid development of novel sensors, imaging technology,
and analysis methods, numerous infrastructure platforms have been developed for phenotyping.
Deep Software Variability and Frictionless Reproducibility
Deep Software Variability and Frictionless ReproducibilityUniversity of Rennes, INSA Rennes, Inria/IRISA, CNRS
The ability to recreate computational results with minimal effort and actionable metrics provides a solid foundation for scientific research and software development. When people can replicate an analysis at the touch of a button using open-source software, open data, and methods to assess and compare proposals, it significantly eases verification of results, engagement with a diverse range of contributors, and progress. However, we have yet to fully achieve this; there are still many sociotechnical frictions.
Inspired by David Donoho's vision, this talk aims to revisit the three crucial pillars of frictionless reproducibility (data sharing, code sharing, and competitive challenges) with the perspective of deep software variability.
Our observation is that multiple layers — hardware, operating systems, third-party libraries, software versions, input data, compile-time options, and parameters — are subject to variability that exacerbates frictions but is also essential for achieving robust, generalizable results and fostering innovation. I will first review the literature, providing evidence of how the complex variability interactions across these layers affect qualitative and quantitative software properties, thereby complicating the reproduction and replication of scientific studies in various fields.
I will then present some software engineering and AI techniques that can support the strategic exploration of variability spaces. These include the use of abstractions and models (e.g., feature models), sampling strategies (e.g., uniform, random), cost-effective measurements (e.g., incremental build of software configurations), and dimensionality reduction methods (e.g., transfer learning, feature selection, software debloating).
I will finally argue that deep variability is both the problem and solution of frictionless reproducibility, calling the software science community to develop new methods and tools to manage variability and foster reproducibility in software systems.
Exposé invité Journées Nationales du GDR GPL 2024
Equivariant neural networks and representation theory
Or: Beyond linear.
Abstract: Equivariant neural networks are neural networks that incorporate symmetries. The nonlinear activation functions in these networks result in interesting nonlinear equivariant maps between simple representations, and motivate the key player of this talk: piecewise linear representation theory.
Disclaimer: No one is perfect, so please mind that there might be mistakes and typos.
dtubbenhauer@gmail.com
Corrected slides: dtubbenhauer.com/talks.html
Bob Reedy - Nitrate in Texas Groundwater.pdf
Presented at June 6-7 Texas Alliance of Groundwater Districts Business Meeting
Cytokines and their role in immune regulation.pptx
This presentation covers the content and information on "Cytokines " and their role in immune regulation .
Sharlene Leurig - Enabling Onsite Water Use with Net Zero Water
Sharlene Leurig - Enabling Onsite Water Use with Net Zero WaterTexas Alliance of Groundwater Districts
Presented at June 6-7 Texas Alliance of Groundwater Districts Business MeetingAuthoring a personal GPT for your research and practice: How we created the Q...
Thematic analysis in qualitative research is a time-consuming and systematic task, typically done using teams. Team members must ground their activities on common understandings of the major concepts underlying the thematic analysis, and define criteria for its development. However, conceptual misunderstandings, equivocations, and lack of adherence to criteria are challenges to the quality and speed of this process. Given the distributed and uncertain nature of this process, we wondered if the tasks in thematic analysis could be supported by readily available artificial intelligence chatbots. Our early efforts point to potential benefits: not just saving time in the coding process but better adherence to criteria and grounding, by increasing triangulation between humans and artificial intelligence. This tutorial will provide a description and demonstration of the process we followed, as two academic researchers, to develop a custom ChatGPT to assist with qualitative coding in the thematic data analysis process of immersive learning accounts in a survey of the academic literature: QUAL-E Immersive Learning Thematic Analysis Helper. In the hands-on time, participants will try out QUAL-E and develop their ideas for their own qualitative coding ChatGPT. Participants that have the paid ChatGPT Plus subscription can create a draft of their assistants. The organizers will provide course materials and slide deck that participants will be able to utilize to continue development of their custom GPT. The paid subscription to ChatGPT Plus is not required to participate in this workshop, just for trying out personal GPTs during it.
Shallowest Oil Discovery of Turkiye.pptx
The Petroleum System of the Çukurova Field - the Shallowest Oil Discovery of Türkiye, Adana
Applied Science: Thermodynamics, Laws & Methodology.pdf
When I was asked to give a companion lecture in support of ‘The Philosophy of Science’ (https://shorturl.at/4pUXz) I decided not to walk through the detail of the many methodologies in order of use. Instead, I chose to employ a long standing, and ongoing, scientific development as an exemplar. And so, I chose the ever evolving story of Thermodynamics as a scientific investigation at its best.
Conducted over a period of >200 years, Thermodynamics R&D, and application, benefitted from the highest levels of professionalism, collaboration, and technical thoroughness. New layers of application, methodology, and practice were made possible by the progressive advance of technology. In turn, this has seen measurement and modelling accuracy continually improved at a micro and macro level.
Perhaps most importantly, Thermodynamics rapidly became a primary tool in the advance of applied science/engineering/technology, spanning micro-tech, to aerospace and cosmology. I can think of no better a story to illustrate the breadth of scientific methodologies and applications at their best.
3D Hybrid PIC simulation of the plasma expansion (ISSS-14)
3D Particle-In-Cell (PIC) algorithm,
Plasma expansion in the dipole magnetic field.
8.Isolation of pure cultures and preservation of cultures.pdf
Isolation of pure culture, its various method.
Immersive Learning That Works: Research Grounding and Paths Forward
We will metaverse into the essence of immersive learning, into its three dimensions and conceptual models. This approach encompasses elements from teaching methodologies to social involvement, through organizational concerns and technologies. Challenging the perception of learning as knowledge transfer, we introduce a 'Uses, Practices & Strategies' model operationalized by the 'Immersive Learning Brain' and ‘Immersion Cube’ frameworks. This approach offers a comprehensive guide through the intricacies of immersive educational experiences and spotlighting research frontiers, along the immersion dimensions of system, narrative, and agency. Our discourse extends to stakeholders beyond the academic sphere, addressing the interests of technologists, instructional designers, and policymakers. We span various contexts, from formal education to organizational transformation to the new horizon of an AI-pervasive society. This keynote aims to unite the iLRN community in a collaborative journey towards a future where immersive learning research and practice coalesce, paving the way for innovative educational research and practice landscapes.
Randomised Optimisation Algorithms in DAPHNE
Slides from talk:
Aleš Zamuda: Randomised Optimisation Algorithms in DAPHNE .
Austrian-Slovenian HPC Meeting 2024 – ASHPC24, Seeblickhotel Grundlsee in Austria, 10–13 June 2024
https://ashpc.eu/
waterlessdyeingtechnolgyusing carbon dioxide chemicalspdf
The technology uses reclaimed CO₂ as the dyeing medium in a closed loop process. When pressurized, CO₂ becomes supercritical (SC-CO₂). In this state CO₂ has a very high solvent power, allowing the dye to dissolve easily.
bordetella pertussis.................................ppt
Bordettela is a gram negative cocobacilli spread by air born drop let
Recently uploaded (20)
THEMATIC APPERCEPTION TEST(TAT) cognitive abilities, creativity, and critic...
THEMATIC APPERCEPTION TEST(TAT) cognitive abilities, creativity, and critic...
Deep Software Variability and Frictionless Reproducibility
Deep Software Variability and Frictionless Reproducibility
Equivariant neural networks and representation theory
Equivariant neural networks and representation theory
Cytokines and their role in immune regulation.pptx
Cytokines and their role in immune regulation.pptx
Sharlene Leurig - Enabling Onsite Water Use with Net Zero Water
Sharlene Leurig - Enabling Onsite Water Use with Net Zero Water
Basics of crystallography, crystal systems, classes and different forms
Basics of crystallography, crystal systems, classes and different forms
Authoring a personal GPT for your research and practice: How we created the Q...
Authoring a personal GPT for your research and practice: How we created the Q...
Applied Science: Thermodynamics, Laws & Methodology.pdf
Applied Science: Thermodynamics, Laws & Methodology.pdf
3D Hybrid PIC simulation of the plasma expansion (ISSS-14)
3D Hybrid PIC simulation of the plasma expansion (ISSS-14)
aziz sancar nobel prize winner: from mardin to nobel
aziz sancar nobel prize winner: from mardin to nobel
8.Isolation of pure cultures and preservation of cultures.pdf
8.Isolation of pure cultures and preservation of cultures.pdf
Immersive Learning That Works: Research Grounding and Paths Forward
Immersive Learning That Works: Research Grounding and Paths Forward
waterlessdyeingtechnolgyusing carbon dioxide chemicalspdf
waterlessdyeingtechnolgyusing carbon dioxide chemicalspdf
bordetella pertussis.................................ppt
bordetella pertussis.................................ppt
Ocean Mammals
- 1. A ghost gene leaves ocean mammals vulnerable to some pesticides Submitted by : Nasir Mahmud Student ID: 1511125162 Session: 2014-15 Submitted to : Dr. Mohammad Shariar Shovon Associate Professor Department of Biochemistry and Molecular Biology University of Rajshahi Course No : BMB-402 Course Title : Advanced Metabolism
- 3. Gene which vulnerable to some pesticides > Paraoxonase1 ( PON1) What does PON1 do? > The gene, PON1 carries instructions for making a protein which can break down toxic chemicals found in popular class of pesticides called organophosphates. > PON1 broke down two organophosphate chemicals - Chlorpyrifos oxon and Diazoxon in some marine species.
- 4. Experimental evidence Blood samples from marine and semiaquatic mammals (blue) with a faulty version of a gene called PON1, as well as a mouse with the gene knocked out, showed that most of the animals didn’t break down two organophosphate pesticide chemicals — chlorpyrifos oxon and diazoxon.