Osteoarthritis is a chronic condition that causes breakdown of cartilage in joints, resulting in pain, swelling, and loss of motion. It most commonly affects weight-bearing joints like the hips and knees. Risk factors include age, genetics, excess weight, and joint injuries. Osteoarthritis can profoundly impact one's physical and mental health by limiting mobility and social activities. Treatment focuses on reducing pain and inflammation through medications, exercise, weight loss, and sometimes surgery like joint replacement for severe cases.