This document outlines plans for an Obstetrical Intensive Care Program with the goals of:
1) Providing comprehensive critical care expertise for obstetric patients through a dedicated program.
2) Serving as a model for critical care of obstetric patients in the Midwest region.
3) Ensuring optimal outcomes for mothers, fetuses, and newborns through collaboration between obstetric, neonatal, and critical care teams.
The program would admit patients requiring intensive monitoring and treatment for conditions such as preeclampsia, postpartum hemorrhage, heart disease, infections, and multi-organ dysfunction. It aims to improve outcomes over traditional ICUs through staff trained in obstetric critical
This document discusses critical care for obstetric patients. It begins with an introduction and epidemiology section noting that while the proportion of obstetric patients in ICUs is low, the most common reasons for admission are postpartum hemorrhage and hypertensive disorders. It then covers obstetric critical care, basic principles for obstetric emergencies, transfer to critical care settings, the role of obstetricians, resuscitative hysterotomy, and supportive care. It provides recommendations including prioritizing maternal stabilization, consulting obstetricians, and not withholding necessary treatments due to fetal concerns. The document aims to guide management of critically ill obstetric patients.
Thromboprophylaxis in pregnancy and puerperiumManju Puri
This presentation is about thromboprophylaxis in pregnancy and puerperium and describes the risk assessment , indications, drugs to be used, when to start, for how long to continue.
Organizing an obstetrical critical care unit drmcbansal
The document discusses the need for organizing an obstetrical critical care unit. It notes that 0.5-1% of obstetrical admissions require intensive care, decreasing mortality by 10 times. An obstetrical ICU requires a multidisciplinary team including skilled obstetricians, intensivists, respiratory therapists, trained nursing staff, and clinical pharmacists to provide specialized care for critically ill pregnant patients. The nursing staff in particular requires high-risk obstetric training and a 1:1 nurse to patient ratio is recommended. Protocols and guidelines should be established to ensure standardized, quality care is provided across the multidisciplinary team.
Day care obstetrics and gynecology provides inpatient level care to patients on an outpatient basis. It was first established in 1969 in the US and has since expanded globally. Day care allows for monitoring of high-risk pregnancies, infertility procedures, fetal medicine procedures, and gynecological surgeries. Patients are selected based on surgical, medical, and social criteria to ensure safety. Procedures are performed using local anesthesia, IV sedation, or general anesthesia with rapid induction and recovery. Strict discharge criteria involving patient status and availability of a caretaker ensure safe recovery at home.
THIS WAS PRESENTED AT SAFOG MOGS "SMART CONFERENCE "IN MUMBAI
PREPARED WITH HELP OF DR SUCHITRA PANDIT,DR CN PURANDARE AND DR ALPESH GANDHI.....VIDEOS CAN BE SEEN AT U TUBE
This document summarizes presentations on maternal near miss in Sudan. It defines maternal near miss as a severe life-threatening complication during pregnancy, childbirth, or postpartum that requires urgent intervention to prevent death. The document discusses how analyzing near miss cases can provide insights into health system failures in obstetric care. It notes that the leading causes of near miss in Sudan are hemorrhage, infection, hypertensive disorders, and anemia. The document also outlines Sudan's policy on identifying near miss criteria and qualitative research examining determinants of maternal morbidity and mortality in post-conflict areas.
This document discusses placenta accreta syndrome, including risk factors, diagnostic methods, and management strategies. It begins with an overview of placenta accreta classifications. Ultrasound and MRI are important diagnostic tools, with ultrasound being the primary method. Risk factors include prior c-sections, placenta previa, and uterine surgeries. Early diagnosis allows for elective c-section and interventions like arterial embolization to reduce bleeding. Hysterectomy is often needed to control hemorrhage but conservative approaches aim to preserve the uterus. Proper multidisciplinary care and prevention of delays in management can improve outcomes for this serious condition.
Maternal collapse during pregnancy and puerperiumDoc Nadia
The document discusses maternal collapse during pregnancy and postpartum. It defines maternal collapse and identifies women at risk. Common causes include hemorrhage, thromboembolism, amniotic fluid embolism, cardiac disease, sepsis, and other medical conditions. The initial management of maternal collapse follows resuscitation guidelines, securing the airway, providing oxygen, performing chest compressions if needed, and administering IV fluids and medications. If collapse occurs after 20 weeks gestation and there is no response to 4 minutes of CPR, perimortem cesarean delivery should be performed within 5 minutes to help maternal resuscitation efforts.
This document discusses critical care for obstetric patients. It begins with an introduction and epidemiology section noting that while the proportion of obstetric patients in ICUs is low, the most common reasons for admission are postpartum hemorrhage and hypertensive disorders. It then covers obstetric critical care, basic principles for obstetric emergencies, transfer to critical care settings, the role of obstetricians, resuscitative hysterotomy, and supportive care. It provides recommendations including prioritizing maternal stabilization, consulting obstetricians, and not withholding necessary treatments due to fetal concerns. The document aims to guide management of critically ill obstetric patients.
Thromboprophylaxis in pregnancy and puerperiumManju Puri
This presentation is about thromboprophylaxis in pregnancy and puerperium and describes the risk assessment , indications, drugs to be used, when to start, for how long to continue.
Organizing an obstetrical critical care unit drmcbansal
The document discusses the need for organizing an obstetrical critical care unit. It notes that 0.5-1% of obstetrical admissions require intensive care, decreasing mortality by 10 times. An obstetrical ICU requires a multidisciplinary team including skilled obstetricians, intensivists, respiratory therapists, trained nursing staff, and clinical pharmacists to provide specialized care for critically ill pregnant patients. The nursing staff in particular requires high-risk obstetric training and a 1:1 nurse to patient ratio is recommended. Protocols and guidelines should be established to ensure standardized, quality care is provided across the multidisciplinary team.
Day care obstetrics and gynecology provides inpatient level care to patients on an outpatient basis. It was first established in 1969 in the US and has since expanded globally. Day care allows for monitoring of high-risk pregnancies, infertility procedures, fetal medicine procedures, and gynecological surgeries. Patients are selected based on surgical, medical, and social criteria to ensure safety. Procedures are performed using local anesthesia, IV sedation, or general anesthesia with rapid induction and recovery. Strict discharge criteria involving patient status and availability of a caretaker ensure safe recovery at home.
THIS WAS PRESENTED AT SAFOG MOGS "SMART CONFERENCE "IN MUMBAI
PREPARED WITH HELP OF DR SUCHITRA PANDIT,DR CN PURANDARE AND DR ALPESH GANDHI.....VIDEOS CAN BE SEEN AT U TUBE
This document summarizes presentations on maternal near miss in Sudan. It defines maternal near miss as a severe life-threatening complication during pregnancy, childbirth, or postpartum that requires urgent intervention to prevent death. The document discusses how analyzing near miss cases can provide insights into health system failures in obstetric care. It notes that the leading causes of near miss in Sudan are hemorrhage, infection, hypertensive disorders, and anemia. The document also outlines Sudan's policy on identifying near miss criteria and qualitative research examining determinants of maternal morbidity and mortality in post-conflict areas.
This document discusses placenta accreta syndrome, including risk factors, diagnostic methods, and management strategies. It begins with an overview of placenta accreta classifications. Ultrasound and MRI are important diagnostic tools, with ultrasound being the primary method. Risk factors include prior c-sections, placenta previa, and uterine surgeries. Early diagnosis allows for elective c-section and interventions like arterial embolization to reduce bleeding. Hysterectomy is often needed to control hemorrhage but conservative approaches aim to preserve the uterus. Proper multidisciplinary care and prevention of delays in management can improve outcomes for this serious condition.
Maternal collapse during pregnancy and puerperiumDoc Nadia
The document discusses maternal collapse during pregnancy and postpartum. It defines maternal collapse and identifies women at risk. Common causes include hemorrhage, thromboembolism, amniotic fluid embolism, cardiac disease, sepsis, and other medical conditions. The initial management of maternal collapse follows resuscitation guidelines, securing the airway, providing oxygen, performing chest compressions if needed, and administering IV fluids and medications. If collapse occurs after 20 weeks gestation and there is no response to 4 minutes of CPR, perimortem cesarean delivery should be performed within 5 minutes to help maternal resuscitation efforts.
Maternal collapse is a life-threatening medical emergency defined as an acute event involving the cardiorespiratory systems and brain in a pregnant or recently pregnant woman, resulting in a reduced or absent level of consciousness. Prompt resuscitation is essential, beginning with shaking and shouting to assess responsiveness, calling for help, providing oxygen, and performing CPR with manual left uterine displacement. If there is no return of spontaneous circulation after 4 minutes of CPR, perimortem cesarean section should be performed within 5 minutes. Thorough documentation, incident reporting, training, and debriefing are important for clinical governance following maternal collapse. Outcomes depend on the underlying cause, location, speed of response, and provider skills
Placenta Accreta Spectrum Disorders Challenges and managementAhmed Elbohoty
This document discusses placenta accreta spectrum disorders, including challenges in management. Key points include: PAS disorders occur when the placenta invades the uterine wall abnormally. Risk factors include prior c-sections and placenta previa. Incidence has risen with increasing c-section rates. Ultrasound is used to diagnose but risks false positives/negatives. Management involves a multidisciplinary team and individualized delivery timing/plan. Surgery poses challenges like hemorrhage, but techniques like leaving the placenta in situ and internal iliac ligation can help. Careful dissection is needed to avoid injury to structures like the bladder and ureters.
Amniotic fluid embolism (AFE) occurs when amniotic fluid enters maternal circulation, most commonly during labor and delivery. It can cause respiratory failure, cardiogenic shock, and disseminated intravascular coagulation. Symptoms are nonspecific initially but may progress rapidly to include hypoxia, cardiac collapse, and seizures. While the exact cause is unknown, it is thought to involve an immune response or abnormal substances in amniotic fluid. Prompt diagnosis and treatment of hypoxia, shock, and coagulopathy is needed but outcomes remain poor, with maternal mortality rates around 60-90%.
This document discusses morbidly adherent placenta, which occurs when the placenta attaches abnormally deeply into the uterine wall. The incidence has increased from 1 in 2500 deliveries in the 1980s to 1 in 553 deliveries in 2015. Risk factors include prior C-sections, uterine surgery, and multiple pregnancies. Ultrasound is useful for diagnosis but may miss some cases. Management options include C-section hysterectomy, leaving the placenta in situ, myometrial resection, the triple P procedure, compression sutures, and lower segment folding. Conservative options have high risks of infection and bleeding requiring additional surgery.
Placenta praevia, placenta praevia accreta and vasa praeviaAboubakr Elnashar
This document provides guidelines for screening, diagnosis, management and delivery planning for three conditions: placenta praevia, placenta accreta, and vasa praevia. For placenta praevia and suspected accreta, routine ultrasound screening at 20 weeks is recommended, with follow up imaging based on findings. Management involves preventing anemia, planning for possible preterm labor and hemorrhage. Delivery planning includes consent discussions, availability of blood products, and ensuring appropriate staff and facilities are available. For placenta accreta, conservative management of the placenta is preferable to disruption if possible. Vasa praevia screening is not routinely recommended, but diagnosis is by ultrasound and management involves
This document discusses respiratory problems in pregnancy including tuberculosis (TB), pneumonia, and acute respiratory distress syndrome (ARDS). It provides details on the incidence, risk factors, clinical presentation, diagnostic criteria, and management recommendations for each condition. TB in pregnancy can lead to adverse maternal and neonatal outcomes if left untreated. Community-acquired pneumonia is one of the most common lung infections in pregnancy and requires prompt antibiotic treatment. ARDS is a serious condition characterized by hypoxemic respiratory failure and diffuse lung infiltrates. Sepsis, aspiration, and conditions unique to pregnancy such as preeclampsia can potentially cause ARDS in pregnant women.
This document discusses the role of anticoagulants in pregnancy. It describes different types of anticoagulants including unfractionated heparin, low molecular weight heparin, warfarin, and newer oral anticoagulants. It provides dosing guidelines for prophylactic and therapeutic uses of unfractionated heparin and low molecular weight heparins in pregnancy. It also discusses indications, monitoring, switching between anticoagulants during pregnancy and postpartum, contraindications, and guidelines from organizations like ACOG.
THROMBOPROPHYLAXIS DURING PREGNANCY, LABOUR AND AFTER DELIVERYAboubakr Elnashar
The document provides guidelines for assessing risk of venous thromboembolism (VTE) in pregnancy and recommending thromboprophylaxis. It states that all women should be assessed for VTE risk factors in early pregnancy and if risk factors develop. It recommends screening women with a previous VTE for inherited thrombophilia. Women with a previous VTE or additional risk factors may qualify for low molecular weight heparin prophylaxis during pregnancy and for 6 weeks postpartum depending on their specific risks.
This document discusses the diagnosis and management of two obstetric emergency cases. The first case involves a 26-year-old pregnant woman at 8 months gestation presenting with vaginal bleeding. This is diagnosed as antepartum haemorrhage, which can be caused by placental abruption or placenta previa. Ultrasound is used to differentiate between the two. The second case involves a woman who just gave birth with continuous bleeding. This is diagnosed as postpartum haemorrhage, which is most commonly caused by uterine atony. Management of both cases involves initial resuscitation, identifying the cause, controlling bleeding through medical or surgical methods such as uterotonic drugs, compression sutures,
This document discusses uterine rupture and dehiscence. It defines uterine rupture as a disruption of the uterine muscle extending to the uterine serosa or other organs, while uterine dehiscence is a disruption of the uterine muscle with an intact serosa. Risk factors for rupture include prior c-sections, myomectomy scars, and uterine abnormalities. Signs of rupture include severe abdominal pain, vaginal bleeding, maternal tachycardia, and fetal distress. Management involves stabilizing the mother, rapidly delivering the baby via c-section, and potentially performing a hysterectomy. For future pregnancies, women are advised to have planned c-sections or consider permanent contraception due to the risks.
This document discusses complications that can occur during hysteroscopic procedures. It begins by defining various complications such as perforation, bleeding, fluid overload, and infection. It then discusses incidence rates and risk factors for complications. The remainder of the document provides details on specific complications, how to recognize them, and strategies for prevention and management. It emphasizes the importance of proper patient positioning, techniques such as gradual dilation to avoid false passages, and using distension media carefully to prevent fluid overload.
Intrapartum sonography can be used to more accurately assess fetal head position, station, descent, and rotation during labor compared to digital examination alone. It also helps predict success of induction of labor and instrumental delivery. The document outlines the basic technique, objectives, and various clinical applications of intrapartum sonography during different stages of labor.
This study compared outcomes of two methods for delivering an impacted fetal head during cesarean delivery: the "push" method, where the head is pushed through the vagina, versus the "pull" method, also called reverse breech extraction, where the fetus is pulled out by the feet. The study reviewed records of 63 deliveries at a hospital in South India from 2014-2015 that required one of these methods. It found that the pull method was associated with fewer complications for mothers, including less extension of the uterine incision and fewer cases of postoperative fever, compared to the push method. The conclusion is that the pull method appears to be safer for delivering an impacted fetal head during cesarean delivery.
1. Tubal anastomosis or IVF-ET must be considered based on factors like age, tubal damage extent, cost, and patient preference.
2. IVF-ET has a higher per-cycle success rate while tubal anastomosis has a higher cumulative success rate and may be more cost-effective.
3. Both have risks and neither is clearly superior, so options should be discussed individually to help couples feel they explored all options.
1. Pregnancy places significant demands on the cardiovascular system due to increases in blood volume, cardiac output, and heart rate.
2. Common cardiac problems during pregnancy include congenital heart defects, heart failure, and pulmonary hypertension. These conditions can lead to complications for both mother and baby if not properly managed.
3. Testing such as echocardiography and stress testing are used to evaluate cardiac function during pregnancy. Treatment depends on the severity and type of condition, with termination of pregnancy recommended for very high risk cases.
Maternal collapse is defined as an acute event involving the cardiorespiratory systems and/or brain, resulting in reduced or absent consciousness. Potential causes include postpartum hemorrhage, pulmonary embolism, amniotic fluid embolism, cardiac issues, intracranial events, drug overdose, and hypoglycemia. Postpartum hemorrhage is the leading cause and may be due to uterine atony, retained placenta, genital tract lacerations, coagulopathy, or acute uterine inversion. Management involves ABC resuscitation, IV fluids, uterotonic drugs, bimanual compression, exploration or hysterectomy if needed.
1) Pregnancy places significant demands on the cardiovascular system due to increases in blood volume, cardiac output, heart rate and changes in blood pressure and chemistry.
2) Women with preexisting heart conditions like rheumatic heart disease may experience worsening symptoms during pregnancy due to these demands. Care during pregnancy involves monitoring, activity restriction, medication and potential termination if risk is too high.
3) Delivery requires close supervision by obstetricians and cardiologists due to risks of heart failure from labor and postpartum blood loss. Overall maternal mortality is low for mild conditions but can be over 7% for severe illnesses if not properly managed.
This document discusses the approach to cardiac disease in pregnancy. It begins by outlining the normal physiological changes in pregnancy that place additional strain on the cardiovascular system. It then describes a systematic approach to evaluating and monitoring different types of cardiac lesions during pregnancy based on how well they are tolerated by the increased cardiovascular demands. High-risk cardiac conditions that require close monitoring and individualized treatment plans are also outlined.
Management of the critically ill obstetric patient.prof.salahSalah Roshdy AHMED
The document discusses the management of critically ill obstetric patients. It begins by outlining the leading causes of ICU admission for pregnant women as preeclampsia and hemorrhage. It then discusses important considerations when treating critically ill obstetric patients, such as accounting for normal physiological changes of pregnancy and treating the mother and fetus. The document proceeds to discuss specific multi-organ system diseases that can occur in critically ill pregnant patients such as ARDS, shock, and DIC. It concludes by focusing on management of hemorrhage, preeclampsia, and DIC.
Nhi Nguyen is an Intensivist from Nepean Hopsital, with a particular interest in feto-maternal health. She gave this lecture on the Registrar day at the Bedside Critical Care conference 2012 (#BCC3). Go to www.intensivecarenetwork.com for more details.
Maternal collapse is a life-threatening medical emergency defined as an acute event involving the cardiorespiratory systems and brain in a pregnant or recently pregnant woman, resulting in a reduced or absent level of consciousness. Prompt resuscitation is essential, beginning with shaking and shouting to assess responsiveness, calling for help, providing oxygen, and performing CPR with manual left uterine displacement. If there is no return of spontaneous circulation after 4 minutes of CPR, perimortem cesarean section should be performed within 5 minutes. Thorough documentation, incident reporting, training, and debriefing are important for clinical governance following maternal collapse. Outcomes depend on the underlying cause, location, speed of response, and provider skills
Placenta Accreta Spectrum Disorders Challenges and managementAhmed Elbohoty
This document discusses placenta accreta spectrum disorders, including challenges in management. Key points include: PAS disorders occur when the placenta invades the uterine wall abnormally. Risk factors include prior c-sections and placenta previa. Incidence has risen with increasing c-section rates. Ultrasound is used to diagnose but risks false positives/negatives. Management involves a multidisciplinary team and individualized delivery timing/plan. Surgery poses challenges like hemorrhage, but techniques like leaving the placenta in situ and internal iliac ligation can help. Careful dissection is needed to avoid injury to structures like the bladder and ureters.
Amniotic fluid embolism (AFE) occurs when amniotic fluid enters maternal circulation, most commonly during labor and delivery. It can cause respiratory failure, cardiogenic shock, and disseminated intravascular coagulation. Symptoms are nonspecific initially but may progress rapidly to include hypoxia, cardiac collapse, and seizures. While the exact cause is unknown, it is thought to involve an immune response or abnormal substances in amniotic fluid. Prompt diagnosis and treatment of hypoxia, shock, and coagulopathy is needed but outcomes remain poor, with maternal mortality rates around 60-90%.
This document discusses morbidly adherent placenta, which occurs when the placenta attaches abnormally deeply into the uterine wall. The incidence has increased from 1 in 2500 deliveries in the 1980s to 1 in 553 deliveries in 2015. Risk factors include prior C-sections, uterine surgery, and multiple pregnancies. Ultrasound is useful for diagnosis but may miss some cases. Management options include C-section hysterectomy, leaving the placenta in situ, myometrial resection, the triple P procedure, compression sutures, and lower segment folding. Conservative options have high risks of infection and bleeding requiring additional surgery.
Placenta praevia, placenta praevia accreta and vasa praeviaAboubakr Elnashar
This document provides guidelines for screening, diagnosis, management and delivery planning for three conditions: placenta praevia, placenta accreta, and vasa praevia. For placenta praevia and suspected accreta, routine ultrasound screening at 20 weeks is recommended, with follow up imaging based on findings. Management involves preventing anemia, planning for possible preterm labor and hemorrhage. Delivery planning includes consent discussions, availability of blood products, and ensuring appropriate staff and facilities are available. For placenta accreta, conservative management of the placenta is preferable to disruption if possible. Vasa praevia screening is not routinely recommended, but diagnosis is by ultrasound and management involves
This document discusses respiratory problems in pregnancy including tuberculosis (TB), pneumonia, and acute respiratory distress syndrome (ARDS). It provides details on the incidence, risk factors, clinical presentation, diagnostic criteria, and management recommendations for each condition. TB in pregnancy can lead to adverse maternal and neonatal outcomes if left untreated. Community-acquired pneumonia is one of the most common lung infections in pregnancy and requires prompt antibiotic treatment. ARDS is a serious condition characterized by hypoxemic respiratory failure and diffuse lung infiltrates. Sepsis, aspiration, and conditions unique to pregnancy such as preeclampsia can potentially cause ARDS in pregnant women.
This document discusses the role of anticoagulants in pregnancy. It describes different types of anticoagulants including unfractionated heparin, low molecular weight heparin, warfarin, and newer oral anticoagulants. It provides dosing guidelines for prophylactic and therapeutic uses of unfractionated heparin and low molecular weight heparins in pregnancy. It also discusses indications, monitoring, switching between anticoagulants during pregnancy and postpartum, contraindications, and guidelines from organizations like ACOG.
THROMBOPROPHYLAXIS DURING PREGNANCY, LABOUR AND AFTER DELIVERYAboubakr Elnashar
The document provides guidelines for assessing risk of venous thromboembolism (VTE) in pregnancy and recommending thromboprophylaxis. It states that all women should be assessed for VTE risk factors in early pregnancy and if risk factors develop. It recommends screening women with a previous VTE for inherited thrombophilia. Women with a previous VTE or additional risk factors may qualify for low molecular weight heparin prophylaxis during pregnancy and for 6 weeks postpartum depending on their specific risks.
This document discusses the diagnosis and management of two obstetric emergency cases. The first case involves a 26-year-old pregnant woman at 8 months gestation presenting with vaginal bleeding. This is diagnosed as antepartum haemorrhage, which can be caused by placental abruption or placenta previa. Ultrasound is used to differentiate between the two. The second case involves a woman who just gave birth with continuous bleeding. This is diagnosed as postpartum haemorrhage, which is most commonly caused by uterine atony. Management of both cases involves initial resuscitation, identifying the cause, controlling bleeding through medical or surgical methods such as uterotonic drugs, compression sutures,
This document discusses uterine rupture and dehiscence. It defines uterine rupture as a disruption of the uterine muscle extending to the uterine serosa or other organs, while uterine dehiscence is a disruption of the uterine muscle with an intact serosa. Risk factors for rupture include prior c-sections, myomectomy scars, and uterine abnormalities. Signs of rupture include severe abdominal pain, vaginal bleeding, maternal tachycardia, and fetal distress. Management involves stabilizing the mother, rapidly delivering the baby via c-section, and potentially performing a hysterectomy. For future pregnancies, women are advised to have planned c-sections or consider permanent contraception due to the risks.
This document discusses complications that can occur during hysteroscopic procedures. It begins by defining various complications such as perforation, bleeding, fluid overload, and infection. It then discusses incidence rates and risk factors for complications. The remainder of the document provides details on specific complications, how to recognize them, and strategies for prevention and management. It emphasizes the importance of proper patient positioning, techniques such as gradual dilation to avoid false passages, and using distension media carefully to prevent fluid overload.
Intrapartum sonography can be used to more accurately assess fetal head position, station, descent, and rotation during labor compared to digital examination alone. It also helps predict success of induction of labor and instrumental delivery. The document outlines the basic technique, objectives, and various clinical applications of intrapartum sonography during different stages of labor.
This study compared outcomes of two methods for delivering an impacted fetal head during cesarean delivery: the "push" method, where the head is pushed through the vagina, versus the "pull" method, also called reverse breech extraction, where the fetus is pulled out by the feet. The study reviewed records of 63 deliveries at a hospital in South India from 2014-2015 that required one of these methods. It found that the pull method was associated with fewer complications for mothers, including less extension of the uterine incision and fewer cases of postoperative fever, compared to the push method. The conclusion is that the pull method appears to be safer for delivering an impacted fetal head during cesarean delivery.
1. Tubal anastomosis or IVF-ET must be considered based on factors like age, tubal damage extent, cost, and patient preference.
2. IVF-ET has a higher per-cycle success rate while tubal anastomosis has a higher cumulative success rate and may be more cost-effective.
3. Both have risks and neither is clearly superior, so options should be discussed individually to help couples feel they explored all options.
1. Pregnancy places significant demands on the cardiovascular system due to increases in blood volume, cardiac output, and heart rate.
2. Common cardiac problems during pregnancy include congenital heart defects, heart failure, and pulmonary hypertension. These conditions can lead to complications for both mother and baby if not properly managed.
3. Testing such as echocardiography and stress testing are used to evaluate cardiac function during pregnancy. Treatment depends on the severity and type of condition, with termination of pregnancy recommended for very high risk cases.
Maternal collapse is defined as an acute event involving the cardiorespiratory systems and/or brain, resulting in reduced or absent consciousness. Potential causes include postpartum hemorrhage, pulmonary embolism, amniotic fluid embolism, cardiac issues, intracranial events, drug overdose, and hypoglycemia. Postpartum hemorrhage is the leading cause and may be due to uterine atony, retained placenta, genital tract lacerations, coagulopathy, or acute uterine inversion. Management involves ABC resuscitation, IV fluids, uterotonic drugs, bimanual compression, exploration or hysterectomy if needed.
1) Pregnancy places significant demands on the cardiovascular system due to increases in blood volume, cardiac output, heart rate and changes in blood pressure and chemistry.
2) Women with preexisting heart conditions like rheumatic heart disease may experience worsening symptoms during pregnancy due to these demands. Care during pregnancy involves monitoring, activity restriction, medication and potential termination if risk is too high.
3) Delivery requires close supervision by obstetricians and cardiologists due to risks of heart failure from labor and postpartum blood loss. Overall maternal mortality is low for mild conditions but can be over 7% for severe illnesses if not properly managed.
This document discusses the approach to cardiac disease in pregnancy. It begins by outlining the normal physiological changes in pregnancy that place additional strain on the cardiovascular system. It then describes a systematic approach to evaluating and monitoring different types of cardiac lesions during pregnancy based on how well they are tolerated by the increased cardiovascular demands. High-risk cardiac conditions that require close monitoring and individualized treatment plans are also outlined.
Management of the critically ill obstetric patient.prof.salahSalah Roshdy AHMED
The document discusses the management of critically ill obstetric patients. It begins by outlining the leading causes of ICU admission for pregnant women as preeclampsia and hemorrhage. It then discusses important considerations when treating critically ill obstetric patients, such as accounting for normal physiological changes of pregnancy and treating the mother and fetus. The document proceeds to discuss specific multi-organ system diseases that can occur in critically ill pregnant patients such as ARDS, shock, and DIC. It concludes by focusing on management of hemorrhage, preeclampsia, and DIC.
Nhi Nguyen is an Intensivist from Nepean Hopsital, with a particular interest in feto-maternal health. She gave this lecture on the Registrar day at the Bedside Critical Care conference 2012 (#BCC3). Go to www.intensivecarenetwork.com for more details.
This document discusses maternity care practices and how they affect breastfeeding. It provides information on:
1) The benefits of breastfeeding for mother, baby, and society in terms of health, economic and environmental impacts.
2) Elements of maternity care that can support breastfeeding including prenatal nutrition, breast examinations, discussing barriers to breastfeeding, and the importance of practitioner knowledge.
3) Practices that can negatively impact breastfeeding like induction of labor, IV fluids, narcotic pain medications, cesarean sections, early cord clamping and suctioning of newborns.
4) The importance of immediate skin-to-skin contact and rooming-in to support breastfeeding
This document discusses three obstetric emergencies: retained placenta, adherent placenta, and inversion of the uterus. For retained placenta, it defines it as occurring when the placenta remains in the uterus 30 minutes after delivery. Manual removal of the placenta is described as the management. Adherent placenta occurs when the placenta does not separate from the uterine wall, and types include placenta accreta, increta, and percreta. Inversion of the uterus is defined as the uterus turning inside out, and can be caused by fundal pressure or cord traction after delivery. Replacement by working from the cervix to fundus is the first step
The document discusses maternal mortality, defining it as the death of a woman during or within 42 days of pregnancy termination from pregnancy-related causes. It provides global and Indian statistics on maternal mortality and approaches to measure it. The leading causes of maternal death worldwide and in India are discussed. Preventive measures to reduce maternal mortality are outlined, including antenatal care, skilled birth attendance, emergency obstetric care, and addressing social determinants. Initiatives taken in India like maternal death audits and clinical guidelines developed in Kerala are also summarized.
The reproductive child health programme was launched in 1997 with the main aims of reducing infant and maternal mortality rates. It has elements of safe motherhood, child survival, and fertility regulation. The objectives include meeting all contraceptive needs, reducing infant and maternal morbidity and mortality rates.
The programme interventions include essential and emergency obstetric care, immunization services, and interventions for maternal, neonatal and child health. It provides drugs, medical equipment and kits to different levels of healthcare facilities. The programme has been implemented in two phases with the second phase strengthening referral systems and integrating management of neonatal and childhood illnesses.
In India, roughly one maternal death occurs every five minutes. Maternal mortality is defined as the death of a woman during or within 42 days of pregnancy termination from pregnancy-related causes. The highest maternal mortality rates in 2010 were in Chad, Somalia, Central African Republic, Sierra Leone and Burundi, while the lowest were in Estonia and Singapore. Though India's maternal mortality ratio has declined from 400 in 1997 to 212 per 100,000 live births in 2007-2009, it still has a long way to go to meet its Millennium Development Goal of 109 by 2015. Anemia and unsafe abortion are significant causes of maternal death in India. National initiatives aim to strengthen antenatal, intranatal and
The document discusses critical care, describing the intensive care team, critical care nursing, the seven Cs of critical care, and the roles of critical care nurses, units, and physicians. It outlines staffing requirements for critical care units, including nurses, respiratory therapists, and physician subspecialists who should be available to treat critically ill patients.
National health programs are one of the measures taken by the government of India to improve the health status of the people.National health Programs useful to controlling or eradicating diseases which cause considerable morbidity and mortality in India
which are either centrally sponsored
initial assessment of critically ill patients(PRESENTED AT IMA HOUSE,CUTTACK)Prerna Biswal
1. A 52-year-old male presented with severe breathlessness and sweating for 5 hours and was admitted to the ICU in a critically ill state.
2. Initial assessment and resuscitation focused on the ABCDE approach to address airway, breathing, circulation, disability and exposure/environment. Basic investigations were sent.
3. The patient was diagnosed with an acute exacerbation of COPD. He was treated with oxygen, steroids, bronchodilators and antibiotics. Due to worsening, non-invasive ventilation was added and the patient showed gradual improvement.
This document discusses severe maternal morbidity, also known as near-misses, which are life-threatening complications during pregnancy, childbirth, or postpartum that women survive only through medical intervention. It notes that over 50 million women experience maternal health issues annually. The document then provides definitions of near-miss cases and discusses risk factors. It presents statistics on near-miss cases from a private hospital in India compared to a rural hospital, finding higher rates in the rural hospital. The leading causes of near-misses are identified as pre-eclampsia/eclampsia and hemorrhage. The conclusion emphasizes the need for improved management of near-miss cases to reduce maternal mortality.
The document outlines several national health programs in India focused on improving child health. Key programs discussed include:
1. The Reproductive and Child Health Program which aims to reduce infant, child, and maternal mortality rates.
2. The Universal Immunization Program which aims to achieve 100% immunization coverage of various diseases.
3. The Integrated Child Development Services scheme which provides supplementary nutrition, immunization, health checkups and education to children under 6.
4. Several national nutritional programs focused on reducing anemia, iodine deficiency disorders, and providing midday meals.
The document discusses the maternal and child health programme in India. It outlines that MCH programmes aim to improve nutrition, ensure healthy births, and prevent disease among mothers and children. The key activities of MCH programmes are providing medical services from prenatal to postnatal care as well as pediatric care. Community health nurses play an important role in direct care of mothers and children, managing MCH services, and providing health education. The goals of the MCH programme are to reduce maternal, infant, and child mortality and morbidity rates.
Maternity and child health care programmeskeshavapavan
The document discusses maternal and child health care services provided at primary health care centers in rural India. It outlines antenatal care including registration, checkups and services; intrapartum care including normal and assisted deliveries; postnatal home visits and newborn care. It also discusses care of children including immunizations and nutrition, family planning services, and adolescent and school health programs. The primary health centers aim to provide these essential services to reduce preventable maternal, newborn and child deaths.
Maternal and child health (MCH) services aim to promote the health of mothers and children. This includes prenatal, intranatal, and postnatal care from conception through early childhood. The goals are to reduce mortality and morbidity through services like antenatal care, safe delivery practices, postpartum care, immunizations, and monitoring of child growth and development. Community health nurses play a key role in providing direct clinical care, health education, and managing MCH programs. Assessment of MCH programs is done using indicators such as maternal mortality rate, infant mortality rate, and under-five mortality rate.
One woman dies every minute from pregnancy or childbirth complications, with 80% being preventable. Maternal mortality is classified as direct, indirect, fortuitous or late. The main causes of maternal death in the state are postpartum hemorrhage, pulmonary embolism, eclampsia, and cardiac disease. The state achieved its MDG 5 target of reducing maternal mortality ratio to below 11.08 per 100,000 live births by 2013. However, deficiencies were still noted and plans of action were proposed to further improve maternal health services and reduce preventable maternal deaths.
This document describes a modified early obstetric warning system (MEOWS) used at Kettering General Hospital. The MEOWS is based on the national early warning score (NEWS) but is modified for use in pregnant and postnatal women. It incorporates standard vital signs measured in NEWS as well as parameters specific to pregnancy like diastolic blood pressure, severity of pain, discharge/lochia, and proteinuria. Scores are assigned based on deviations from normal ranges. Triggers are in place for escalating care based on total scores. The goal is early recognition of deterioration in maternal health.
This document discusses the management of high risk parturients, or pregnant women with medical complications or risk factors. It defines high risk parturients and outlines common medical conditions and obstetric risks that classify women as high risk. The document discusses strategies for assessing risk, creating individualized obstetric and anesthesia plans, and ensuring appropriate care for high risk women during labor, delivery and emergencies. It emphasizes the importance of a multidisciplinary team approach, systems to facilitate safe handovers of care, and the need for regional high risk obstetric databases and audits to continually improve care for this patient population.
High risk approach in maternal and child healthShrooti Shah
This document discusses high risk approaches in maternal and child health. It defines high risk pregnancies and cases according to the WHO. It describes screening high risk cases and managing them, including proper antenatal, intranatal and neonatal care. It discusses interventions to reduce maternal mortality such as skilled birth attendants. It also discusses referral systems and maternal, newborn and child health policies and programs in Nepal.
This document outlines the aims of critical care management for obstetric patients. It discusses how the physiological changes of pregnancy can complicate diagnosis and treatment. The goals of management are to ensure adequate oxygen delivery and tissue perfusion while also considering the fetus. Specific organ systems like cardiovascular and respiratory systems are discussed. Management may involve resuscitation, monitoring, supportive therapies, and consideration of delivery depending on gestational age and maternal/fetal status. A multidisciplinary approach is emphasized.
1. Maternal mortality is a major issue in developing countries, where 99% of maternal deaths occur. The leading causes are direct obstetric complications and indirect medical conditions exacerbated by pregnancy.
2. Emergency obstetric care (EmOC) provides life-saving interventions for direct obstetric complications and must be available 24/7. International goals aim to increase access to and quality of EmOC.
3. Ensuring basic and comprehensive EmOC requires essential equipment, skilled birth attendants, clinical protocols, financial access, and emergency transport systems between facilities.
Antenatal care aims to ensure a healthy pregnancy and delivery for both mother and baby. It involves regular checkups including medical history, examinations, tests and education. The document outlines the definition, goals, models and process of antenatal care. It discusses the traditional model involving monthly visits and a newer WHO model with a minimum of eight contacts. Key aspects of antenatal care covered include comprehensive maternity services, risk assessment, monitoring of mother and baby, and addressing issues that could impact pregnancy outcomes.
This document discusses high risk approaches in maternal and child health. It defines high risk pregnancies as those complicated by factors that can adversely impact maternal or neonatal outcomes. Approximately 20-30% of pregnancies are considered high risk. The document outlines various risk factors to screen for during antenatal exams and describes how to manage high risk cases through close monitoring, early interventions, specialized care, and strengthening the healthcare system and community support networks. Traditional approaches like risk screening and antenatal care are important but have limitations in predicting and preventing life-threatening complications, demonstrating that all pregnancies carry some risk.
Maternal mortality remains a significant issue worldwide, with over 500,000 deaths annually. Through initiatives like the Confidential Enquiries into Maternal Deaths system, Malaysia has significantly reduced its maternal mortality rate from 540/100,000 live births in 1950 to 28.1/100,000 in 2000. Postpartum hemorrhage is a leading cause of death in Malaysia, while medical conditions, sepsis, and hypertensive disorders also contribute substantially. Recommendations focus on increasing access to emergency care and transportation, improving provider training, and expanding family planning programs.
This document discusses organ transplantation and pregnancy. It begins by introducing that organ transplantation is life-saving but can restore fertility, and that successful pregnancies have occurred in transplant recipients. It then summarizes key details on pregnancies in recipients of kidney, liver, pancreas/kidney, heart/lung, and intestine transplants. Important considerations for transplant recipients planning pregnancy include optimal timing, vaccination, contraception, preconception counseling, and close monitoring during high-risk pregnancies. Factors that can influence pregnancy outcomes are also outlined.
The document discusses the organization and setup of a Neonatal Intensive Care Unit (NICU). It describes the personnel, equipment, and facilities required in a NICU. Key personnel include neonatologists, nurses, respiratory therapists, and other support staff. Essential equipment includes incubators, monitors to assess vital signs, oxygen supplies, feeding equipment, and ventilators. Transport of sick infants to the NICU is also addressed, emphasizing the importance of stabilizing infants before transferring and maintaining their body temperature. Nurses play an important role in providing physical, emotional and family support to critically ill newborns in the NICU.
This study examined perinatal outcomes in 131 pregnancies among women with sickle cell disease (SCD) receiving care at a hospital in London between 2007-2017. The pregnancies of women with SCD were matched to 1310 unaffected pregnancies based on ethnicity and year of delivery. The study found higher risks of stillbirth, preeclampsia, preterm birth, and admission to the neonatal unit among pregnancies of women with SCD compared to unaffected pregnancies, after adjusting for maternal characteristics. Limitations included limited power to examine associations with maternal and fetal mortality and lack of data for some outcomes in the comparison group.
maternal_survival_sepsis_guidelines_mgmh_20_2.pptxDr. Tara D
- The document presents a case of maternal sepsis that was initially missed due to lack of fever and clear infection source, as well as elevated white blood cell count being attributed to betamethasone rather than infection.
- It discusses the vulnerability of pregnant women to sepsis, risk factors, definitions and guidelines for managing maternal sepsis. Early recognition is key, but screening tools have limitations due to normal physiological changes in pregnancy.
- A two-step approach is recommended for diagnosis of maternal sepsis - an initial screening with vital signs and white blood cell count, followed by tests to evaluate end organ dysfunction if screening is positive. This helps address the limitations of single screening tools in pregnancy.
This document provides information on prenatal care and female reproduction. It defines a midwife as a health professional trained to support women during pregnancy, labor, birth, and postnatal care. It discusses the nursing process used in midwifery. It also outlines the three levels of care - clinics, community health centers, and district/tertiary hospitals - and their respective functions, staffing, and facilities. Finally, it covers topics like the female reproductive system, fertilization process, and standards for record keeping in midwifery.
Esta es la actualización sobre criterios y manejo de Sindrome Hipertensivo del embarazo que se han comenzado a usar este año.
Publicación actualmente no liberada.
Nuevos criterios diagnósticos de preeclampsia
Actualización 2013-2014 de sindrome hipertensivo del embarazo ACOG
Hypertensionin pregnancy ACOG Actualización Diciembre 2013
'National Standards for Bereavement Care Following Pregnancy Loss and Perinat...Irish Hospice Foundation
'National Standards for Bereavement Care Following Pregnancy Loss and Perinatal Death' (Presentation at Maternity and Neonatal Network, April 2015) [MNN 13]
The proportion of births assisted by a skilled provider has increased from 6% in 2000 to 26% in 2011, and to 28% in 2016.
- Place of delivery: Home deliveries remain high at 84% of births in the five years preceding the survey.
- Delivery assistance: The majority of births (72%) are assisted by relatives or traditional birth attendants. Only 28% are assisted by a skilled provider.
- Regional variation: Institutional deliveries range from 2% in Somali region to 46% in Addis Ababa.
- Wealth quintile: Women in the highest wealth quintile are over seven times more likely to deliver in a health facility compared to women in the lowest wealth quintile (
Risk profiling, multiple long term conditions & complex patients, integrated ...Dr Bruce Pollington
Dr Bruce Pollington web-ex presentation to LTC QIPP programme
Utilising risk profiling, and risk stratification to identify patients with multiple long term conditions requiring complex care through integrated care teams.
Neonatal intensive care nurses provide care for premature and sick newborns. An associate's or bachelor's degree in nursing is required along with certification from passing a national exam. These nurses can work in Level II-IV neonatal intensive units that care for babies with different needs. They may become specialists in areas like development. Ethical issues around access to care, costs, and outcomes must be considered. National organizations like AWHONN support neonatal nurses through advocacy, education and setting standards of practice.
Similar to Obstetrical Intensive Care Program (20)
This document discusses fetal surgery techniques and criteria. It outlines various prenatal interventions that can be performed including transplacental treatments, needle-based procedures, fetoscopic surgeries, and open repairs. Fetal surgery is performed to treat conditions where prenatal diagnosis is possible, the natural history is known, and there are no effective postnatal treatments. Interventions are done in specialized centers according to strict protocols and ethics approval. Examples of conditions treated include spina bifida, twin-twin transfusion syndrome (TTTS), and lower urinary tract obstruction (LUTO). The document presents data from trials demonstrating improved outcomes for fetal surgery compared to postnatal care for conditions like myelomeningocele (MMC).
Implementing American Heart Association Practice Standards for Inpatient ECG ...Allina Health
Implementing American Heart Association Practice Standards for Inpatient ECG Monitoring: An Interventional Study at Abbott Northwestern Hospital presented by Kristin Sandau, PhD, RN
This study aimed to examine the impact of acupuncture on pain, nausea, anxiety and coping in women undergoing mastectomy surgery. The study involved a randomized controlled trial where women were assigned to either receive acupuncture post-surgery or usual care. Results found that acupuncture was effective in reducing anxiety, improving coping ability, and decreasing pain and nausea, with statistically significant differences between the acupuncture and usual care groups. Limitations included a small sample size and lack of diversity. Future research could involve a larger, more diverse population and exploring optimal timing of acupuncture interventions.
The document discusses using data and analytics to drive improvements in healthcare. It outlines the components of a data-driven organization, including an enterprise data warehouse, metrics, predictive models, protocols, and governance. It also discusses how analytics can help healthcare providers transition to value-based payments by measuring quality, reducing variation, and eliminating waste. Specific examples are provided on how one healthcare system used data to reduce variation in spine care, lower bleeding complications after PCI procedures, identify drug cost opportunities in knee replacements, and lower supply costs for lumbar fusion procedures.
Critical Care Research: Connection to PracticeAllina Health
1) The document discusses a critical care research program at Abbott Northwestern Hospital with the goals of conducting studies to improve patient outcomes, enhance quality of care, and reduce costs.
2) The program involves intensivists, hospitalists, and other clinical specialties conducting studies and presenting findings to improve practice.
3) Several ongoing studies are summarized that examine issues like postoperative monitoring, pulmonary ultrasound scoring, infection risks, and outcomes after procedures.
Enhancing Mental Health Care Transitions: A Recovery-Based ModelAllina Health
The document describes a pilot program between Abbott Northwestern Hospital and five community mental health agencies to improve care transitions for mental health patients. The program hired a Mental Health Navigator and Peer Support Specialist to enhance discharge planning and establish outpatient services. Initial outcomes include a 30% reduction in readmissions, increased engagement in recovery planning, and positive patient experiences and feedback. The success of the program is attributed to improved communication, care coordination, and a focus on patient engagement through trusting relationships and recovery-oriented services.
New Results from National Institutes of Health R01 GrantAllina Health
This document summarizes the results of a National Institutes of Health grant studying integrative medicine (IM) at a large hospital. Key findings include:
- Median time to first IM referral varied by clinical service line, from under 5 hours for oncology to over 2 days for mental health.
- Analysis of IM therapies for joint replacement, oncology, and cardiovascular patients found significant reductions in pain and anxiety scores post-treatment.
- A pilot study of acupuncture in the emergency department found it reduced pain scores significantly, with many patients able to avoid opioid pain medications.
- Future studies are planned to analyze the data and publish results in 2016-2017, including understanding factors influencing IM therapy selection and examining
Cancer genetic counseling services provide important benefits for those with and without cancer. Genetic counselors educate patients about their cancer risks, help patients understand genetic testing results, and empower informed decision making. While genetic testing identifies only a small percentage of cancer cases, it allows for targeted treatment and screening that can prevent cancer in families. Expanding access to genetic risk assessment and counseling could help identify more high-risk individuals and families earlier to reduce cancer burden through prevention and early detection strategies.
This document provides information on lung cancer screening. It discusses:
1) The purpose of screening is to detect cancer early before symptoms appear when treatment may be more effective.
2) Screening can save lives for some individuals but also causes small harms for many through unnecessary follow up testing from false positives. Care must be taken to balance these benefits and harms.
3) Effective screening requires a organized program with eligibility criteria, shared decision making, low-dose CT scans interpreted by experts and with multidisciplinary teams available to evaluate and treat any abnormalities found. Data collection is also important to monitor outcomes.
Responsive Neurostimulation (RNS) for Intractable EpilepsyAllina Health
The RNS system is an FDA-approved treatment for drug-resistant epilepsy that involves surgically implanting a neurostimulator device to detect and respond to seizure activity. Clinical trials found that the RNS system provided a median seizure reduction of over 37% within 3 months for treated patients compared to a 25.2% reduction for the sham group. Long-term follow-up over 7 years found the RNS system maintained seizure control effectiveness and was safe, with no chronic neurological effects reported. The RNS system may be an option for patients who have failed two or more anti-seizure medications and are not candidates for resective epilepsy surgery.
Pituitary Adenoma: How Registry and Statistical Learning Can Improve Care and...Allina Health
1. Statistical learning techniques like hierarchical clustering and k-means clustering were used to analyze immunohistochemistry (IHC) data from pituitary adenoma samples to develop a more accurate and efficient diagnostic algorithm.
2. The new algorithm stratifies adenomas into gonadotroph, corticotroph, or "null" categories based on expression of SF-1, Pit-1, and ACTH, reducing the number of required IHCs.
3. Testing on an independent validation set found the new algorithm provided a more accurate diagnosis in 39 of 59 cases compared to previous methods, using one-third fewer IHCs on average.
Mother Baby Mental Health Program: Use of Technology & Team-Based Care to Ext...Allina Health
The document discusses a perinatal mental health program that uses team-based care and technology to extend its reach. It highlights strategic initiatives like establishing provider networks, web-based cognitive behavioral therapy, and a perinatal psychiatry consultation line to support providers. The program aims to improve identification and treatment of perinatal mental illness by increasing treatment options, educating providers, and implementing standardized care processes.
The Evolution and Outcomes of Pharmacist Medication History ServicesAllina Health
The document discusses the evolution of pharmacist medication history services at Abbott Northwestern Hospital. It describes challenges with accurate medication histories and additional services pharmacists provide, such as obtaining medication lists from outside sources. The presentation reviews two patient cases where pharmacist involvement led to improved outcomes by identifying an overdose and undisclosed herbal supplement use. Data demonstrates pharmacists can reduce adverse drug events and hospital costs by enhancing medication reconciliation.
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
These lecture slides, by Dr Sidra Arshad, offer a simplified look into the mechanisms involved in the regulation of respiration:
Learning objectives:
1. Describe the organisation of respiratory center
2. Describe the nervous control of inspiration and respiratory rhythm
3. Describe the functions of the dorsal and respiratory groups of neurons
4. Describe the influences of the Pneumotaxic and Apneustic centers
5. Explain the role of Hering-Breur inflation reflex in regulation of inspiration
6. Explain the role of central chemoreceptors in regulation of respiration
7. Explain the role of peripheral chemoreceptors in regulation of respiration
8. Explain the regulation of respiration during exercise
9. Integrate the respiratory regulatory mechanisms
10. Describe the Cheyne-Stokes breathing
Study Resources:
1. Chapter 42, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 36, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 13, Human Physiology by Lauralee Sherwood, 9th edition
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
Adhd Medication Shortage Uk - trinexpharmacy.comreignlana06
The UK is currently facing a Adhd Medication Shortage Uk, which has left many patients and their families grappling with uncertainty and frustration. ADHD, or Attention Deficit Hyperactivity Disorder, is a chronic condition that requires consistent medication to manage effectively. This shortage has highlighted the critical role these medications play in the daily lives of those affected by ADHD. Contact : +1 (747) 209 – 3649 E-mail : sales@trinexpharmacy.com
TEST BANK For Community Health Nursing A Canadian Perspective, 5th Edition by...Donc Test
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Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
2. 2
Mission
• Collaboration with already comprehensive high-risk perinatal services and transfer program
• Ultimately to make a significant difference in the lives of our antenatal/postnatal mothers
with critical complications of pregnancy
• Dedicated program to provide comprehensive critical care expertise for obstetric patients
3. 3
GOAL
• MODEL OF THE ONLY PROGRAM WITHIN THE MIDWEST REGION DEDICATED TO CRITICAL
CARE OBSTETRIC ILLNESS
• 24/7 One Call Transfer to the Unit: 612-863-1000
• Collaboration with our team as well as neonatal physicians/APRN’s/Pediatric surgical team
within the MBC/MWFCC/Minneapolis + St Paul Children’s to provide the most advanced
treatment therapies available to ensure optimal outcome for mother/fetus/newborn as the
central focus
• Patient care, teaching, and research efforts to provide and improve state of the art care of
critically ill obstetric patients will remain the central focus to enhance and optimize their
care and serve as a model for future generations of mothers and babies
4. 4
Measurable Milestones/Benefits
• Training and maintaining up to date critical care knowledge
• Ensuring state of the art care across the system which can be measured in CME/simulation
and advancing similar knowledge based criteria and performance
• Improved educational opportunities for residents and fellows, who DO NOT have that
availability within their academic training programs
• Each of the above HIGHLIGHT the unique opportunity for MBCSL/Critical Care Medicine
partnership to provide that training and to be the “premier” provider for the program
5. 5
Measurable Milestones/Benefits
• Close and direct bedside critical care:
– Problems detected earlier
– Complications averted/prevented
• Subtle changes in maternal/fetal
condition not always reflected in
patient notes: “Can only be detected
by serial observation at the bedside"
• Complex/Continuity of care will be
readily organized within single
Obstetric ICU
• OB team will gain knowledge and
expertise in hemodynamic
monitoring
• Reduce need to transfer patient “off
service” to individuals who do not
possess same knowledge base of the
unique physiologic and
hemodynamic variables attributable
to pregnancy (pre/post delivery)
6. 6
Current Resources
• Seamless continuity with Neonatal
team
• Dedicated nursing/cross cover with
special expertise in critical obstetric
illness
• ACLS/Antepartum FHR monitoring
expertise
• In room 24/7 availability of multi-
channel hemodynamic monitor
assessment
• Point of Care Ultrasound expertise
for
– Extended Focused Assessment with
Sonography for Trauma (eFAST)
– ECHO
– Aorta/IVC
– Intra-abdominal
– DVT/vascular access
• Designated Critical Care bed system
within newly designed Critical Care
Unit*
7. 7
ANW Critical Care/OB Partnership
Model
Intensivist
Obstetrical
Patient in ICU
*Team Nursing (ICU/OB RN Partnership)
1. Key interactions for optimal patient care
a. Bedside shift report (ICU & OB RN at bedside)
b. Multidisciplinary rounds (MDRs) (11am PB2000, ? H4100/4200)
2. OB RN assigned to ICU patient
a. Come to ICU for bedside shift report with ICU RN
b. Care Team huddles throughout shift (need to further define when, how
often)
Supportive Consultants
NICU-NNP &
Neuonatology
Lactation Consultant
Subspecialties
Maternal Fetal Medicine
Respiratory Therapy
ICU & Perinatal Nurse*
Medical Specialist
Clinical Pharmacist
Family
Neonatal Providers
ICU Clinical Nurse Specialists
Social Work-
ICU, OB, NICU
Spiritual Care
OB & ICU RNCCs
OB Clinical Practice Coordinator
Dietician
8. 8
Criteria for Obstetric Intensive Care Program Admission
• Successful epidemiologic evaluation of any particular disease has several prerequisites:
– Condition should be accurately defined
– Measurable outcomes of interest
– Systematic way of data collection or surveillance that allows measurement of the outcomes of
interest and associated risk factors
• Epidemiologic evaluation of critical illness associated with pregnancy has met with mixed
success on all these accounts
9. 9
Criteria for Obstetric Intensive Care Program Admission
• Focus traditionally based on the well-defined outcome of maternal mortality in order to
identify illnesses or conditions that might lead to maternal death
• Maternal mortality in US 11.5/100,00 live births
• Tracking maternal death may not be best way to assess pregnancy-related critical illness
• “Death represents only the tip of the iceberg, the size of which is unknown”
10. 10
Criteria for Obstetric Intensive Care Program Admission
• Each of several conditions complicating pregnancy (preexisting or complicated by
pregnancy) can and are associated with significant complications that have the potential for
serious morbidity, disability, and mortality
• Stage which condition becomes severe enough to be classified as critical illness has not
been clearly defined
• More helpful to consider critical illness as IMPENDING, DEVELOPING, or ESTABLISHED organ
dysfunction, that can lead to long-term morbidity or death
• Allows flexibility as conditions can deteriorate quickly
11. 11
Criteria for Obstetric Intensive Care Program Admission
• Specific surveillance systems to track severe complications of pregnancy NOT associated
with maternal mortality are lacking
• Most women suffering from critical illness in pregnancy will spend some time in an ICU
setting
• Cases are described as “near miss” mortality cases
• 2/3 of maternal deaths occur in WOMEN WHO NEVER REACH and ICU
12. 12
ICU Mortality of Obstetric Patients and Prediction by APACHE II
score
• APACHE II Scores of 10-14 should correlate with and ~ 15% mortality rate in
patients admitted to ICU without preceding surgery and ~ 7% admitted
following surgery
• ICU mortality in the “all obstetric admissions” was 2.3% (APACHE II-10.9) and in
non-obstetric cohort was 14.7% (APACHE II-13.7)
• Second study in same group mortality was 3.2% in “currently pregnant” group
(APACHE II -12), 1.7% in “recently pregnant” group (APACHE II-10.4) and 11% in
the non-obstetric group (APACHE II-13.3)
Intensive Care and National Audit Research Centre (ICNARC). Female admissions (aged 16-50 years) to adult, general critical care units in England, Wales, and Northern Ireland, reported as ”currently pregnant” or ”recently pregnant.” 1
January 2007 to 3 December 2007
Harrison DA, Penny JA, etal. Critical Care. 2005:9:s25
13. 13
IMPACT
•APACHE II scores over predict mortality in the obstetric ICU
population
–Possible explanations:
• Hypertensive disease of pregnancy and hemorrhage account for the majority
of ICU admissions
• Each can cause significant physiologic derangements (leading to higher APACHE
II scores) but are relatively self-limited when supportive and urgent operative
care is provided
• Adaptive changes in physiologic parameters in pregnancy WOULD BE DEEMED
abnormal by APACHE II scoring criteria
• Combined, adaptive physiologic parameters at presentation are relatively out
of step with clinical course
–Argues for new/unique scoring system for obstetric ICU patients
14. 14
Cause of death in Obstetric Patients in
ICU
• Hypertensive disease: 26%
• Respiratory (pneumonia, AFE, ARDS, PE): 20%
• Cardiac (Eisenmenger’s complex, MI/arrhythmia/cardiomyopathy): 12%
• OB Hemorrhage: 10%
• CNS Hemorrhage: 7%
• Infection/Sepsis: 8%
• Malignancy: 6%
Cantwell R, Clutton-Brock T, Cooper G, et al. Saving Mothers’ Lives: reviewing maternal deaths to make motherhood safer
2006-2008
Eighth Report of the Confidential Enquiries into Maternal Deaths in the UK. BJOG. 2011; 118 (supp 1): 1-203
15. 15
Admission criteria to Obstetric Intensive Care Program
Important to recognize that BOTH the pregnant patient with
deteriorating health status secondary to comorbid medical conditions
and the healthy pregnant patient that is unstable from obstetric
complications may equally benefit from care in the ICU
Aggressive management in a DEDICATED OBSTETRICAL CRITICAL CARE
PROGRAM vs ”general ICU” of this patient population, combined with
their overall better health status, YIELD LOWER MORBIDITY AND
MORTALITY RATES
16. 16
Overview of obstetric critical illness by organ system
• Hypertensive disorders (acute/chronic hypertensive emergencies)
• Morbidly adherent placenta complexities (integrated into the Center of Excellence for the
diagnosis and surgical management of abnormal placentation within the Mother Baby
Center)
• Corrected/acquired maternal congenital heart disease (CHD)
• Endocrine crises:
– Diabetic Ketoacidosis
– Thyroid storm
– Adrenal crises
17. 17
Overview of obstetric critical illness by organ system
• Infectious disease complicated by:
– Systemic Inflammatory Response Syndrome (SIRS)/Sepsis
– Septic shock
– Multisystem end organ dysfunction/failure
• Renal disease
– Acute Kidney Injury (AKI)
– Chronic Kidney Disease (CKD)
– End Stage Renal Disease (ESRD)
– Continuous/intermittent renal replacement therapy (CRRT)/Dialysis
18. 18
Overview of obstetric critical illness by organ system
• Complicated chemical dependency: Withdrawal
• Thromboembolism/Pulmonary embolism/amniotic fluid anaphylaxis
• Oncology
• Neurologic
– CVA/Neuro thromboembolic emergency
– Seizure disorders
– Eclampsia and sequelae
19. 19
Dedicated Team: multidisciplinary experts
• 24/7 Critical Care Intensivists
• 24/7 Critical Care/Surgical MFM Specialists
• Invasive/Non-invasive cardiology including acute/chronic heart failure team
• Collaborative educational programs for ICU and Obstetric Nurses
• State of the art facilities with current up to date technology/monitoring (mother and fetus)
including:
– Point of care focused ultrasound/echocardiography with immediate non-invasive hemodynamic
monitoring
– Immediate availability of invasive hemodynamic monitoring
– ECMO (V/A and VV)
20. 20
Dedicated Team: multidisciplinary experts
• Collaborative team of subspecialists:
– Pediatric Cardiology
– Pediatric Cardiology subspecialized in the management of adults with corrected congenital heart
lesions
– Urology/Nephrology
– Anesthesia team specially trained in the critical care management of obstetric patients with life
threatening maternal cardiac disease
– Oncology specialists
– Cardiothoracic/Vascular Surgery 24/7 immediate availability
21. 21
Dedicated Comprehensive Medical Services
• Respiratory Therapy (RCAT)
• All current modes of ventilator therapy tailored to patient needs and underlying respiratory
compromise
• Adult/Neonatal ECMO
• Transfusion experts for complications of massive transfusion therapy with ROTEM
integration
• Continuous remote cardiac telemetry as needed
22. 22
Background
• Recent case series suggest between 0.1% and 0.8% of obstetric patients are admitted to
“traditional ICU”
• Risk of death ranges from 2% to 11%, mortality substantially higher than the maternal
mortality ratio in the developed world
• In addition, 1-2% pregnant patients receive critical care outside of a traditional ICU but
within dedicated obstetric care unit
• Overall estimates 1-3% of pregnant women require critical care services
23. 23
Background
• Unique Hemodynamic and other physiologic adaptations that occur in pregnancy poses
exceptional challenges in this patient population
• Knowledge of these physiologic adaptations and specific pregnancy-related disorders is
mandatory for optimal management
• Dedicated Obstetric ICU is designed to fit this need and bridge the critical care delivery
from traditional ICU units.
24. 24
Benefits of obstetric dedicated ICU not realized by traditional ICU
setting
• Intensive care personnel dedicated and trained in the observation and organization of the
unit allows for prevention of complications and early recognition and treatment of
complications
• Familiarity and cross training of resources of both invasive/non-invasive monitoring will
provide prompt, rational treatment of hemodynamically unstable patients
• Continuity of care for mother, fetus, and neonate will be improved before and after
delivery
25. 25
Benefits of obstetric dedicated ICU not realized by traditional ICU
setting
• Multidisciplinary teaching program will foster up to date information for
residents/fellows/attending's to ensure “state of the art” care to improve quality of
outcomes, in particular those rare complications of pregnancy that will need transfer to our
quaternary center
• Provide a broad spectrum of patients in which research in the area of hemodynamic
compromise related to pregnancy can be maintained and contributions to the literature
may be ensured to provide insight into evidence based critical care management
26. 26
Integrated program/patient profiles
• Quaternary center of referral for > 5000 deliveries/year (MBC)
• Referral base for metropolitan and more broadly, instate/outstate within the Midwest
region
• Growth potential for the program likely to increase exponentially
• No existing Midwest Regional Center for the critically ill obstetric patient exists in current
format to bridge the outpatient/inpatient clinical expertise
• Integrated outpatient program with Maternal Obstetric Medical and Surgical complications
of pregnancy subspecialty clinic (MOMS)
27. 27
Integrated program/patient profiles
• Seamless program to enhance the overall quality of care with improved outcomes to
provide the “only dedicated Center of Excellence in this area” within our region
• Measurable outcomes for the most seriously ill and at risk for critical illness:
– LOS
– Morbidity
– Mortality
– Readmission to ICU
28. 28
Overview of Criteria for OB
ICU Admission and D/C
Massive
Hemorrhage
Eclampsia
Maternal/fetal
collapse
Unexpected
nature of OB
complication
Patients requiring intensive nursing
care and titrated patient care 24/7
Patients with Acute Respiratory
Failure/intubation or at imminent
risk of requiring ventilator
support/airway management
Requiring advanced invasive
hemodynamic monitoring and/or CV
organ support with vasoactive
therapy (inotropes/vasopressors)
Intracranial pressure monitoring
Advance cardiac support (Right/left
heart Cath/cardioversion/arrhythmia
therapy)
Coma
Multisystem end organ failure
29. 29
Minnesota Perinatal Physicians
Marijo Aguilera, MD Suresh Ahanya, MD Elizabeth Baldwin, MD Lea Fairbanks, MD
David Lynch-Salamon, MD Patricia Mills, MD Lisa Saul, MD Heidi Thorson, MD William Wagner, MD Donald Wothe, MD
Meiling Parker, MD Matthew Loichinger MD
Laura Colicchia, MD
30. 30
Criteria for admission
High probability of MI
Hemodynamically unstable
Arrhythmias
Congestive heart failure
Pacing requirement
Urgent/Emergent
hypertensive crises
with/without evidence of
end organ failure
HELLP Syndrome
Eclampsia
Compromised gas
exchange
At risk for impending
respiratory failure
(Asthma/Pneumonia/Pul
monary edema)
Requirement for minute-
minute monitoring of vital
signs
(suspected/confirmed PE )
or need for aggressive
pulmonary physiotherapy
Eclampsia
Seizure from known or
unknown cause
Known prior neurologic
event that places current
maternal well being in
jeopardy
31. 31
Criteria for admission
Need for frequent
neurologic
assessment
Need for continuous
pulmonary/cardiac
monitoring that is at
risk for hemodynamic
instability
UGI/LGI bleeding requiring
transfusion therapy
Hepatic failure:
AFLP
TTP/HUS
Hepatorenal Syndrome
Pancreatitis
DKA
Thyrotoxicosis/Storm
Complicated
parathyroid/calcium
metabolism
Congenital metabolic
disorders
32. 32
Criteria for admission
• Surgical
–Severe hemorrhage requiring
MTP
•Morbidly adherent
placenta
•PPH
•Peripartum hysterectomy
that requires close
monitoring/fluid
resuscitation
• Renal
–Unstable AKI
–Chronic Kidney
Disease/unstable
–CRRT
–Plasmapheresis
34. 34
ANW Mother Baby Center 2016
Maternal Early Warning Signs Identification, Notification, Evaluation and
Escalation Checklist
Verify single abnormal values and increase monitoring (VS and systems/OB assessments)
frequency q 5-15 min until stable and concerns resolved.
Maternal Early Warning Signs
* Temp: < 96.8 F (36C)or >100.4 F (38C)
* Pulse: persistent maternal HR <=50 or >120
* Respiratory rate (RR): <10 or >24
* BP: Systolic <90 mmHg or >=160 mmHg
o Diastolic <45 or >=105
* SaO2 < 95%
* Oliguria:<35 mL for 2 hours, or <0.5 mL/Kg/hr for
2 hours
Maternal Signs/Symptoms:
* Visual changes
* Epigastric pain, upper right quadrant pain
* Absent DTR’s on magnesium sulfate
* Agitation
* Patient with preeclampsia reporting a non-remitting headache or shortness of breath
* Significant bleeding (weigh blood loss) or suspected internal bleeding (see PPH checklist and move to
OR if >1500 cc blood loss and not resolved);
o persistent maternal tachycardia
o abdominal pain or distention
o hypotension
* Concern for infection with abnormal VS (temp and RR as above, Pulse >110, and/or WBC >15 or < 4)
* MAP <70 (Mean arterial pressure = 1/3 pulse pressure + diastolic)
* Severe abdominal pain
* Hypertensive emergency (follow orderset) not controlled within 1 hour, provider to the bedside.
Notify provider. Provider reassess within 1 hour if s/s not resolved
* Notify Community Charge and Team Lead RN
* Notify provider, prompt beside evaluation, & document assessments, interventions,
and communications (urgent concerns call OB Hospitalist)
Provider notification using SBAR, prompt beside evaluation & documentation
Rapid Response (Code Blue as indicated), Call OB Hospitalist, and Anesthesia and notify primary
provider* Chest Pain
* Suspected Sepsis
* Shortness of breath
* Unresponsiveness
* Change in neuro status including;
o Confusion
o Focal neuro deficits
o Seizure
o Suspected stroke
* Unwitnessed fall or fall with suspected injury
* Concern for maternal stability
Provider bedside evaluation:
If provider evaluation is non diagnostic or the
abnormal VS or S/S are felt to reflect normal
physiology for that patient, a plan for
subsequent patient monitoring, re-
notification, and re-evaluation plan should be
communicated and documented by the
provider.
35. 35
Technical Resources
Arterial hemodynamics
CVC Hemodynamics
SvcO2
C𝑣𝑜2
Shunt Fraction
Oxygen Delivery
Cardiac Output (CI/SI)
All ventilator modes
capability
24/7 RCAT
24/7 availability for secure
airway
Fetal monitors for
antepartum/intrapartum
need
Specific birthing beds for
vaginal delivery
Capability for immediate
C/S (Critically ill
patient/fetal
compromise/Peri-
Mortem)
36. 36
Staffing Resources
• Lines of communication that go directly to lab personnel/blood bank in setting of Massive
Transfusion Protocols (MTP)
• Dedicated Critical Care Pharmacy
• RCAT
• Multidisciplinary Intensivists including
– Medical
– Surgical
– Cardiac
– ECMO
37. 37
Staffing Resources
• MFM/Critical Care OB Specialist/Intensivist specialist as Co-Directors of the program
• Minimum of 10 obstetric/cross cover RN/(APRN’s) to assure at least one available for each
bed in unit (24/7)
• All RN’s/APRN’s would have ≧ 2 years of intrapartum care experience or cross cover
intensive care training
• Teaching:
– MFM/Critical Care fellows/Medicine residents to be part of staffing resources and ongoing
educational opportunities provided by staff will be MAJOR FOCUS of education while assigned to unit
38. 38
Staffing Resources
• All nurses to have ability to attend CME’s for obstetric intensive care:
– Adaptive changes in pregnancy that potentially impact critical illness
– Annual OB ICU course commitment that also includes simulation to maintain up to date skills set
– Formal hemodynamic monitor training
– Ventilator management therapy
– Cross cover training in the medical ICU of the L/D nursing team to fill resource requirements with all
certified ACLS
39. 39
Overview of obstetric critical illness by organ system
• Post surgical complications of pregnancy
– Sepsis
– DIC
– Massive Transfusion Protocol (MTP)
• Organ transplant/complications of immunosuppression therapy
• Respiratory disease:
– ARDS
– Acute Lung Injury (ALI)
– Status asthmaticus