Obstetric ultrasonography, or prenatal ultrasound, is the use of medical ultrasonography in pregnancy, in which sound waves are used to create real-time visual images of the developing embryo or fetus in the uterus.
Smart sonography is an ultrasound Diagnostic Centre in Accra. We provide ultrasound services and basic ultrasound training for health practitioners. If you wish to train with us visit our website at www.smartsonography-gh.com.
Obstetrical Ultrasound• Introduced in the late 1950’s ultrasonography is a safe, non- invasive, accurate and cost-effective means to investigate the fetus• Computer generated system that uses sound waves integrated through real time scanners placed in contact with a gel medium to the maternal abdomen• The information from different reflections are reconstructed to provide a continuous picture of the moving fetus on the monitor screen
In this presentation we will discuss
First trimester US especially TVS is an integral part for confirmation of intrauterine pregnancy and to rule out ectopic pregnancy.
First trimester US helps us in suggesting conceptus viability.
First trimester US especially TVS is very efficient in approaching and evaluating the cause of vaginal bleeding.
Obstetric ultrasound uses sound waves to produce pictures of a baby (embryo or fetus) within a pregnant woman, as well as the mother's uterus and ovaries. It does not use ionizing radiation, has no known harmful effects, and is the preferred method for monitoring pregnant women and their unborn babies.
Smart sonography is an ultrasound Diagnostic Centre in Accra. We provide ultrasound services and basic ultrasound training for health practitioners. If you wish to train with us visit our website at www.smartsonography-gh.com.
Obstetrical Ultrasound• Introduced in the late 1950’s ultrasonography is a safe, non- invasive, accurate and cost-effective means to investigate the fetus• Computer generated system that uses sound waves integrated through real time scanners placed in contact with a gel medium to the maternal abdomen• The information from different reflections are reconstructed to provide a continuous picture of the moving fetus on the monitor screen
In this presentation we will discuss
First trimester US especially TVS is an integral part for confirmation of intrauterine pregnancy and to rule out ectopic pregnancy.
First trimester US helps us in suggesting conceptus viability.
First trimester US especially TVS is very efficient in approaching and evaluating the cause of vaginal bleeding.
Obstetric ultrasound uses sound waves to produce pictures of a baby (embryo or fetus) within a pregnant woman, as well as the mother's uterus and ovaries. It does not use ionizing radiation, has no known harmful effects, and is the preferred method for monitoring pregnant women and their unborn babies.
Gestational age is a key piece of data used by healthcare providers to determine the timing of various screening tests and assessments of the fetus and mother throughout pregnancy. Gestational age may be assessed at any time during pregnancy, and several modes of assessment exist, each requiring different equipment or skills and with varying degrees of accuracy. Obtaining more accurate estimates of gestational age through better diagnostic approaches may initiate more prompt medical management of a pregnant patient.
Value of routine ultrasound examination at 35–37 weeks’ gestation in diagnosi...Võ Tá Sơn
Value of routine ultrasound examination at 35–37 weeks’ gestation in diagnosis of fetal abnormalities
Vai trò của siêu âm quý 3 trong phát hiện dị tật thai
Irritable bowel syndrome is a common condition affecting the digestive system.
Symptoms of irritable bowel syndrome include stomach cramps, bloating, diarrhoea and constipation. These may come and go over time.
Making changes to your diet and lifestyle, like avoiding things that trigger your symptoms, can help ease irritable bowel syndrome.
blockage or problem in the urinary tract can mean urine is unable to drain from the kidneys or is able to flow the wrong way up into the kidneys. This can lead to a build-up of urine in the kidneys, causing them to become stretched and swollen.
An injury higher on the spinal cord can cause paralysis in most of your body and affect all limbs (tetraplegia or quadriplegia). A lower injury to the spinal cord may cause paralysis affecting your legs and lower body (paraplegia)
Scoliosis is the abnormal twisting and curvature of the spine. It is usually first noticed by a change in appearance of the back. Typical signs include: a visibly curved spine. one shoulder being higher than the other.
Osteoarthritis (OA) is the most common form of arthritis. Some people call it degenerative joint disease or “wear and tear” arthritis. It occurs most frequently in the hands, hips, and knees.
With OA, the cartilage within a joint begins to break down and the underlying bone begins to change. These changes usually develop slowly and get worse over time. OA can cause pain, stiffness, and swelling. In some cases it also causes reduced function and disability; some people are no longer able to do daily tasks or work.
About 4 out of 5 cases of acute pancreatitis improve quickly and don't cause any serious further problems. However, 1 in 5 cases are severe and can result in life-threatening complications, such as multiple organ failure. In severe cases where complications develop, there's a high risk of the condition being fatal.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
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New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
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The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
2. Ultrasound
orefers to sound waves traveling at a frequency above
20,000 hertz (cycles per second).
oTransducers use wide-bandwidth technology to perform
over a range of frequencies.
o In 2nd trimester, a 4- to 6-megahertz abdominal
transducer is often in close enough proximity to the fetus
to provide precise images.
06/05/2020 2
3. TRANSABDOMINAL
ULTRASOUND
◦ Lower frequency, lower resolution image
◦ Curved linear transducer
◦ Better visualized with full bladder
◦ Can see coronal and sagittal views of
organs and fetus
Bladder
Uterus
06/05/2020 3
4. TRANSVAGINAL ULTRASOUND
◦ Higher frequency, higher resolution image
◦ Endocavitory probe
◦ Better visualized with empty bladder
◦ Can see sagittal or coronal view of uterus
◦ RULE OF THUMB: if possible attempt transabdominal before considering transvaginal to avoid more
invasive procedure.
06/05/2020 4
5. All sonography machines are required to display two indices:
1. Thermal Index
a measure of the relative probability that the examination may raise the
temperature, potentially enough to induce injury.
2. Mechanical Index
a measure of likelihood of adverse effects related to rarefractional
pressure, such as cavitation—which is relevant only in tissues that
contain air.
06/05/2020 5
6. The following guidelines may
help avert injury:
1. Position the patient on the examination table close to you, so that your
elbow is close to your body, with less than 30 degrees shoulder abduction,
keeping your thumb facing up.
2. Adjust the table or chair height so that your forearm is parallel to the floor.
3. If seated, use a chair with back support, support your feet, and keep ankles
in neutral position. Do not lean toward the patient or monitor.
4. Face the monitor squarely and position it so that it is viewed at a neutral
angle, such as 15 degrees downward.
5. Avoid reaching, bending, or twisting while scanning.
6. Frequent breaks may avoid muscle strain. Stretching and strengthening
exercises can be helpful.
06/05/2020 6
7. Indications for Sonography before
14 weeks’ gestation
Confirm an intrauterine pregnancy
Evaluate a suspected ectopic pregnancy
Define the cause of vaginal bleeding
Evaluate pelvic pain
Estimate gestational age
Diagnose or evaluate multifetal gestations
Confirm cardiac activity
Modified from the American Institute of Ultrasound in Medicine, 2013a.
06/05/2020 7
8. Indications for Sonography before
14 weeks’ gestation
Assist chorionic villus sampling, embryo transfer, and localization and
removal of an intrauterine device
Assess for certain fetal anomalies such as anencephaly, in high-risk
patients
Evaluate maternal pelvic masses and/or uterine abnormalities
Measure nuchal translucency when part of a screening program for
fetal aneuploidy
Evaluate suspected gestational trophoblastic disease
Modified from the American Institute of Ultrasound in Medicine, 2013a.
06/05/2020 8
9. Indications for Second or
Third Trimester Ultrasound
Examination
MATERNAL INDICATIONS
Vaginal bleeding
Abdominal/pelvic pain
Pelvic mass
Suspected uterine
abnormality
Suspected ectopic
pregnancy
Suspected molar pregnancy
Suspected placenta previa
and subsequent surveillance
FETAL INDICATIONS
Gestational age estimation
Fetal-growth evaluation
Significant uterine
size/clinical date discrepancy
Suspected multifetal
gestation
Fetal anatomical evaluation
Fetal anomaly screening
Assessment for findings that
may increase the aneuploidy
risk
06/05/2020 9
10. Indications for Second or Third
Trimester Ultrasound Examination
MATERNAL INDICATIONS
Suspected placental
abruption
Preterm premature rupture
of membranes and/or
preterm labor
Cervical insufficiency
Adjunct to cervical cerclage
Adjunct to amniocentesis or
other procedure
Adjunct to external cephalic
version
FETAL INDICATIONS
Abnormal biochemical markers
Fetal presentation determination
Suspected hydramnios or
oligohydramnios
Fetal well-being evaluation
Follow-up evaluation of a fetal
anomaly
History of congenital anomaly in
prior pregnancy
Suspected fetal death
Fetal condition evaluation in late
registrants for prenatal care
06/05/2020 10
11. Components of Standard
Ultrasound Examination by First
Trimester
Gestational sac size, location, and number
Embryo and/or yolk sac identification
Crown-rump length
Fetal number, including amnionicity and chorionicity of multifetal
gestations
06/05/2020 11
12. Components of Standard
Ultrasound Examination by First
Trimester
Embryonic/fetal cardiac activity
Assessment of embryonic/fetal anatomy
appropriate for the first trimester
Evaluation of the maternal uterus, adnexa, and
cul-de-sac
Evaluation of the fetal nuchal region, with
consideration of fetal nuchal translucency
assessment
06/05/2020 12
13. Gestational Sac (GS):
◦ Visible at 4-5wks GA with transvaginal US
◦ Visible at 6 wks GA with transabdominal US
◦ echogenic ring with anechoic center within uterine cavity
◦ Measure by Mean Sac Diameter: average dimensions of
width/length/height of sac
◦ GS size increases by about 1mm/day in early pregnancy
06/05/2020 13
14. Gestational Sac (GS):
Yolk Sac: bright ring with anechoic center located inside GS seen at 5wk GA.
Fetal Pole: represents fetal development at somite stage. Can be seen by
transvaginal US as thickening of yolk at 6wks GA.
Fetal heart beat : usually seen around the time fetal pole is present, further
confirming viability
06/05/2020 14
15. 2nd and 3rd Trimester
sonography
1. Standard sonographic examination
anatomical structures that should be evaluated during
the examination
assessed after approximately 18 weeks
2. Specialized sonographic examinations
targeted examination is a detailed anatomical survey
performed
when an abnormality is suspected on the basis of
standard examination
3. Limited sonographic examination
operform to address a specific clinical question including
amnionic fluid volume assessment, placental location,
or evaluation of fetal presentation or viability
06/05/2020 15
16. Components of Standard
Ultrasound Examination by 2nd
and 3rd Trimester
Fetal number, including amnionicity and chorionicity of multifetal
gestations
Fetal cardiac activity
Fetal presentation
Placental location, appearance, and relationship to the internal
cervical os, with documentation of placental cord insertion site
06/05/2020 16
17. Components of Standard
Ultrasound Examination by 2nd
and 3rd Trimester
Amnionic fluid volume
Gestational age assessment
Fetal weight estimation
Fetal anatomical survey, including documentation of technical
limitations
Evaluation of the maternal uterus, adnexa, and cervix when
appropriate
06/05/2020 17
18. Standard
Examination of Fetal
Anatomy
Head, face, and neck
Lateral cerebral ventricles
Choroid plexus
Midline falx
Cavum septum pellucidi
Cerebellum
Cisterna magna
Upper lip
Nuchal fold
at 15–20weeks
06/05/2020 18
19. Minimal Elements of a Standard
Examination of Fetal Anatomy
Chest
Four-chamber view
Left ventricular
outflow tract
Right ventricular
outflow tract
06/05/2020 19
20. Minimal Elements of a Standard
Examination of Fetal Anatomy
Abdomen
Stomach—presence, size, and situs
Kidneys
Urinary bladder
Umbilical cord insertion into fetal abdomen
Umbilical cord vessel number
06/05/2020 20
21. Minimal Elements of a Standard
Examination of Fetal Anatomy
Spine
Cervical, thoracic, lumbar, and sacral spine
Extremities
Legs and arms
06/05/2020 21
22. Minimal Elements of a Standard
Examination of Fetal Anatomy
Fetal sex
In multifetal gestations and when medically indicated
06/05/2020 22
23. Guidelines for Nuchal
Translucency (NT) Measurement
The margins of NT edges must be clear enough for proper caliper placement
The fetus must be in the midsagittal plane
The image must be magnified so that it is filled by the fetal head, neck, and
upper thorax
The fetal neck must be in a neutral position, not flexed and not
hyperextended
The amnion must be seen as separate from the NT line
Electronic calipers must be used to perform the measurement
The + calipers must be placed on the inner borders of the nuchal space with
none of the horizontal crossbar itself protruding into the space
The calipers must be placed perpendicular to the long axis of the fetus
The measurement must be obtained at the widest space of the NT
06/05/2020 23
24. Nuchal Translucency
Measured during 11-14 wks gestational age
Seen on sagittal image as increased subcutaneous non-septated fluid in
posterior fetal neck
◦ sequential screening with NT: 82-87%
◦ NT alone: 64-70%
06/05/2020 24
25. Fetal Biometry
The estimated gestational age from the crown-rump
length.
Formulas are similarly used to calculate estimated
gestational age and fetal weight from measurements
of the
biparietal diameter head
abdominal circumference
femur length
06/05/2020 25
26. crown rump length (CRL)
◦ Approximately estimates Gestational Age from 7-12wks gestation
◦ Measure longest length of embryo
A Rule of thumb of estimating GA:
6wks + CRL(mm) = 6wks+days
Estimating due date:
◦ For 1st trimester if GA measures within 7days of EDD by LMP then do not
change EDD
◦ For 2nd trimester if GA measures within 10days of EDD by LMP then do not
change EDD
◦ If ultrasound provides EDD more/less than the 7 or 10 days, then EDD is changed
to ultrasound EDD
◦ Once GA confirmed with first trimester CRL, EDD should NOT be changed in
further CRL measurements
06/05/2020 26
29. Amnionic Fluid
Amnionic fluid volume evaluation is a component of every second or third
trimester sonogram.
The normal range for single deepest pocket that is most commonly used is2
to 8 cm
Oligohydramnios
that the volume is below normal range, The sonographic diagnosis is usually
based on an AFI ≤ 5 cm or on a single deepest pocket of amnionic fluid ≤ 2
cm
Hydramnios or polyhydramnios—
is defined as amnionic fluid volume above normal
the ultrasound transducer is held perpendicular to the floor and parallel to
the long axis of the pregnant woman.
The uterus is divided into four equal quadrants—the right- and left-upper
and lower quadrants,respectively.
06/05/2020 29
30. Amniotic Fluid Index
The normal range for AFI that is most commonly used is 5 to 24cm, with
values above and below.
The AFI is the sum of the single deepest pocket from each quadrant.
06/05/2020 30
38. Components of Fetal
Echocardiography
Basic imaging parameters
Evaluation of atria
Evaluation of ventricles
Evaluation of great vessels
Cardiac and visceral situs
Atrioventricular junctions
Ventriculoarterial junctions
06/05/2020 38
46. Motion-mode or M-mode
imaging
linear display of cardiac cycle events, with time on the x-axis and
motion on the y-axis
used to measure fetal heart rate If there is an abnormality of heart rate
or rhythm
permits separate evaluation of atrial and ventricular waveforms
06/05/2020 46
51. THREE- AND FOUR-DIMENSIONAL
SONOGRAPHY
3-D volume is acquired that may be rendered to display images of any
plane— axial, sagittal, coronal, or even oblique—within that volume.
Sequential “slices” can be generated
Technique applications include
evaluation of intracranial anatomy in the sagittal plane (corpus
callosum, palate and skeletal system)
Four-dimensional (4-D) sonography/Real-time 3-D
-allows rapid reconstruction of the
rendered images to convey the impression
that the scanning is in real time. Improves visualization of cardiac
anatomy.
06/05/2020 51
54. Doppler Ultrasound
When sound waves strike a moving target, the frequency of the waves
reflected back is shifted proportionate to the velocity and direction of
that moving target—a phenomenon known as the Doppler shift.
Because the magnitude and direction of the frequency shift depend on
the relative motion of the moving target, Doppler can be used to
evaluate flow within blood vessels.
Doppler waveform and describes
The simplest is the systolic-diastolic ratio (S/D ratio), which compares
the maximal (or peak) systolic flow with end-diastolic flow to evaluate
downstream impedance to flow.
06/05/2020 54