The document discusses nutrition requirements during pregnancy and lactation. It notes that nutritional needs increase tremendously during these periods as the mother must nourish herself as well as the growing fetus or breastfeeding infant. Specifically, it outlines how energy, protein, calcium, iron, vitamin and mineral needs escalate. Meeting these heightened requirements is important for limiting complications and supporting healthy fetal development and birth outcomes. Inadequate nutrition can endanger both mother and baby. The document also covers some potential issues like gestational diabetes, birth defects, and challenges that can arise during delivery or for the newborn.
Nutrition is the study of nutrients in food, how the body uses them, and the relationship between diet, health, and disease.
Nutritionists use ideas from molecular biology, biochemistry, and genetics to understand how nutrients affect the human body.
Calcium citrate malate is most easily absorbed by the body. Calcium is essential for many diverse processes in the body, including bone formation, muscle contraction, and enzyme and hormone functioning. Calcium is very essential in muscle contraction, oocyte activation, building strong bones and teeth, blood clotting, nerve impulse, transmission, regulating heart beat and fluid balance within cells. Calcium supplementation in pregnancy has the potential to reduce adverse gestational outcomes, in particular by decreasing the risk of developing hypertensive disorders during pregnancy, which are associated with a significant number of maternal deaths and considerable risk of preterm birth, the leading cause of early. Calcium citrate maleate and other nutrients are essential for cell growth and the production and functioning of DNA – the body's genetic blueprint. Based on clinical evidences Calsiara™ is essential for Pregnancy Mother and Fetal development. Along with to improve the mineral density of bone.
Nutrition during pregnancy
Nutrition before pregnancy
unhealthy eating trends
Nutrition during pregnancy
important of good Nutrition during pregnancy
Key Nutrition during pregnancy
Optimal weight gain during pregnancy
1st trimester
2nd trimester
3rd trimester
Nutrition during lactation
protein
Sources of vitamins
Nutrition is the study of nutrients in food, how the body uses them, and the relationship between diet, health, and disease.
Nutritionists use ideas from molecular biology, biochemistry, and genetics to understand how nutrients affect the human body.
Calcium citrate malate is most easily absorbed by the body. Calcium is essential for many diverse processes in the body, including bone formation, muscle contraction, and enzyme and hormone functioning. Calcium is very essential in muscle contraction, oocyte activation, building strong bones and teeth, blood clotting, nerve impulse, transmission, regulating heart beat and fluid balance within cells. Calcium supplementation in pregnancy has the potential to reduce adverse gestational outcomes, in particular by decreasing the risk of developing hypertensive disorders during pregnancy, which are associated with a significant number of maternal deaths and considerable risk of preterm birth, the leading cause of early. Calcium citrate maleate and other nutrients are essential for cell growth and the production and functioning of DNA – the body's genetic blueprint. Based on clinical evidences Calsiara™ is essential for Pregnancy Mother and Fetal development. Along with to improve the mineral density of bone.
Nutrition during pregnancy
Nutrition before pregnancy
unhealthy eating trends
Nutrition during pregnancy
important of good Nutrition during pregnancy
Key Nutrition during pregnancy
Optimal weight gain during pregnancy
1st trimester
2nd trimester
3rd trimester
Nutrition during lactation
protein
Sources of vitamins
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
2. “Nutrition requirements increases
tremendously during pregnancy and lactation
as the expectant or nursing mother not only
has to nourish herself but also growing foetus
and the infant who is being breast fed”
2
3. Pregnancy (gestation ) is a period of great physiological
stress for woman as she is nurturing a growing fetus in
her body.
Some changes occur in mother’s body which influences
the need for nutrients & the efficacy with which the
mother’s body uses the nutrients.
A. ↑Basal metabolic rate (BMR): Fetal growth & development
increases the BMR by 5% during 1st trimester and 12% during 2nd
& 3rd trimester. This increases the total energy requirement.
B. Gastrointestinal changes: There is an alteration in GI functions
which causes nausea, constipation & vomiting. In later trimester
of pregnancy absorption of nutrients like vitamin B12, iron and
calcium increases in order to meet the increased needs of the
mother & fetus.
C. Changes in body fluid: Mother’s blood volume increases so as to
carry the appropriate amount of nutrients to the fetus and
metabolic waste away from the fetus. With increase in the blood
volume the concentrations of plasma proteins, hemoglobin and
other blood constituents is lowered
Pregnancy 3
4. Importance of good nutrition during
pregnancy
• Mother has to nurture the fetus, health of the newborn depends on nutritional status of the
mother during and prior to conception.
• A well nourished woman prior to conception enters pregnancy with reserve of several
nutrients that meets the needs of the growing fetus without affecting her own health.
• A well nourished woman suffers fewer complications during pregnancy & there are few
chances of premature births.
• A well nourished mother will give birth to a healthy child
• Maternal diet during pregnancy has a direct influence on fetal growth, size & health of the
newborn.
• Poor diet during pregnancy affects mother’s health, a malnourished mother provides
nutrients to the fetus at the expense of her own tissues
• Poor nutrition during pregnancy increases the risk of complications such as prolonged
labour and even death.
• Inadequate diet during pregnancy affects the health of the baby during early infancy. If the
infants survive they develop nutritional diseases like anemia, rickets etc or suffer from
infectious diseases due to lack of good immunity
4
5. Importance of Nutrition in pre maternal
period & pre natal period
During pregnancy the nutrient needs increases
To develop maternal organs such as uterus, placenta and breast tissues
To build up body reserves to be utilized at the time of delivery and
lactation.
First trimester: During 1st trimester there is no significant increase in
the size of fetus thus only qualitative improvement in nutrients intake is
required during this time.
2nd & 3rd trimester: An increased nutrient intake is suggested in
second & third trimester of pregnancy thus need for almost all the
nutrients is increased during pregnancy.
5
6. Energy
requirement
during
pregnancy
To deposit fat
which will be used
during lactation.
To meet the needs
for increased
basal metabolic
rate
Development of
placenta &
maternal tissues
The growth of
fetus
Energy requirement during pregnancy
6
7. Protein, Ca, and Fe requirements during pregnancy
Growth of fetus
Development of placenta
Enlargement of maternal tissues
Increased maternal blood volume
Formation of amniotic fluid
Protein reserves prepares the mother for labour, delivery and
lactation
Proteins
Growth and development of bones as well as teeth of the fetus.
Calcium intake decreases risk of hypertension, pre-eclampsia in
mothers and low birth weights and chronic hypertension in
new-borns.
Maintaining bone strength
Proper muscle contraction
Blood clotting
Expansion of maternal tissues including the red blood cell mass
Maintaining additional iron content of placenta
Building the iron stores in fetal liver
Compensate blood loss during delivery
7
8. Vitamin requirements during pregnancy
Vitamins A (600 µg/d retinol): It is needed in small amounts to
protect the fetus from immune system problems, blindness,
infections and death.
Vitamin D (5µg/d): It is required for
formation of fetal bones.
Vitamin K: Vitamin K is required for normal coagulation of
blood & prevents new born infants hemorrhages.
Vit B12 (1.2 µg/d) : Vitamin B12 supplementation
during pregnancy helps in brain & nervous system
development of the fetus.
Vit C (60mg/d): It increase iron absorption and also helps
in fetal growth. Deficiency of vitamin C increases the
chances of preterm delivery
Vit B6 (2.5mg/d): It is required for normal
fetal development & positive pregnancy
outcomes.
Vit B1 (+0.2mg/d), B2 (+0.2 mg/d),
B3(+2mg/d): As total energy requirement
increases during pregnancy so B vitamin
requirement also increases.
8
9. Vitamin & Mineral requirements during pregnancy
Folic acid (Vit B9) (RDA- 400 µg/d):
During pregnancy maternal blood formation increases thus
folic acid requirement also increases
Folic acid supplementation during pregnancy prevents fetal
neural tube defects and improves birth weights of the fetus.
Zinc (RDA-12mg/d) :
It is required for synthesis of nucleic acids DNA & RNA and it
is having important role in reproduction.
Zinc deficiency during pregnancy can cause poor pregnancy
outcomes and abnormal deliveries including congenital
malformations.
Iodine : Lack of iodine causes still birth, birth defects
& decreased fetal brain development.
9
Minerals
10. Other considerations during pregnancy
Alcohol: During pregnancy alcohol consumption causes low birth weight infants &
growth retardation, fetal impaired central & nervous system performance including
growth retardation.
Smoking: During pregnancy smoking results in placental abnormalities & fetal
damage, including prematurely & low birth weights. Smoking impairs oxygen &
nutrient transport through the placenta due to reduced blood flow
Drugs: During pregnancy drugs consumption lead to poor prenatal
weight gain, very short or prolonged labour, operative delivery and
other perinatal problems.
10
11. Nutritional requirement during lactation
Protein requirement: During lactation protein needs also
increases as mothers milk contains 1.15g of protein/100ml.
Adequate amounts of good quality protein should be included
in the mother’s diet. During first 6 months of lactation- 75g of
protein is required everyday During 6-12 months of lactation –
68g of protein is required everyday
Calcium: 1g /d Additional calcium is required for breast milk
secretion. 30-40mg of calcium is secreted per 100ml or 300mg
of calcium per 850 ml of milk. Additional intake of calcium is
essential to enable the retention of calcium in breast milk.
Adequate dietary calcium intake during lactation meets the
mother’s calcium needs and extra calcium requirement for
breast milk production.
Iron: 30mg/d Iron requirement during lactation is the addition
of the requirement of the mother & required to make up the
iron secreted in breast milk. Most of the lactating woman have
lactation amenorrhea, resulting in saving of 1mg of iron per day
which would otherwise lost in the menstrual blood. The
requirement of iron is same as the non pregnant woman
11
12. Nutritional requirement during lactation
Vitamin A (950µg/d): Breast milk is rich in vit. A so lactating
mother needs adequate amount of vitamin A in their diet.
Vitamin B6 (2.5mg/d): It’s requirement increases during
lactation.
Vitamin B12 (1.5mg/d): Additional Vitamin B12 is required to
meet the needs of the lactation.
Folic acid (150µg/d): Additional folic acid intake will meet the
needs of the lactation
Vitamin C (25mg/d): Appreciable amount of vitamin C is
secreted in breast milk. Additional intake will meet the need of
the lactation.
12
13. Intrauterine growth restriction (fetal growth
restriction)
A condition in which a baby doesn't grow to normal weight during pregnancy.
13
14. Gestational diabetes mellitus
Gestational diabetes is caused
by hormonal changes in
pregnancy which can change
the body’s ability to use a
substance called insulin. Insulin
is important because it helps
keep blood sugar at a healthy
level. Whilst all women
undergo hormonal changes,
only some women develop
gestational diabetes. This is
likely due to pregnancy related
factors such as the presence of
human placental lactogen that
interferes with susceptible
insulin receptors
14
15. Congenital malformations
Atrial septal defect (ASD)
A birth defect that causes a
hole in the wall between
the heart's upper chambers
(atria).
Ventricular septal defect (VSD)
A heart defect due to an
abnormal connection between
the lower chambers of the
heart (ventricles).
Neural tube defects (NTD) are birth
defects of the brain, spine, or spinal
cord. The two most common neural
tube defects are spina bifida and
anencephaly
Caudal regression syndrome (CRS), or
sacral agenesis (or hypoplasia of the
sacrum), is a congenital disorder in
which there is abnormal fetal
development of the lower spine—the
caudal partition of the spine
Polycystic kidney disease (PKD) is an
inherited disorder in which clusters of
cysts develop primarily within your
kidneys, causing your kidneys to enlarge
and lose function over time.
Renal agenesis is a condition in which a newborn is missing one
or both kidneys. Unilateral renal agenesis (URA) is the absence
of one kidney. Bilateral renal agenesis (BRA) is the absence of
both kidneys.
Duodenal atresia is the congenital
absence or complete closure of a portion
of the lumen of the duodenum. It causes
increased levels of amniotic fluid during
pregnancy (polyhydramnios) and intestinal
obstruction in newborn babies.
1st TRIMESTER
15
16. Congenital
malformations
1.The term "fetal macrosomia“ is
used to describe a newborn who's
significantly larger than average. A
baby diagnosed with fetal
macrosomia has a birth weight of
more than 8 pounds, 13 ounces
(4,000 grams), regardless of his or
her gestational age
1.Perinatal asphyxia, neonatal asphyxia or birth asphyxia is
the medical condition resulting from deprivation of oxygen to a
newborn infant that lasts long enough during the birth process
to cause physical harm, usually to the brain.
2.Shoulder dystocia is a specific case
of obstructed labour whereby after
the delivery of the head, the anterior
shoulder of the infant cannot pass
below, or requires significant
manipulation to pass below, the pubic
symphysis. It is diagnosed when the
shoulders fail to deliver shortly after
the fetal head
2nd TRIMESTER
Delivery
After Delivery
1.Respiratory distress syndrome (RDS)
is a common problem in premature
babies. It causes babies to need extra
oxygen and help with breathing
2.Neonatal jaundice is a yellowish discoloration of the white
part of the eyes and skin in a newborn baby due to high
bilirubin levels
3. Neonatal polycythemia defined as a
venous hematocrit ≥65% (0.65)
16