Professor of Radiology and Medicine
Vice Chair, Academic Affairs
Assistant Dean of Diversity
Director, Quantitative Imaging Center (QIC)
Boston University School of Medicine, Boston, MA
This document summarizes a study of Pigmented Villonodular Synovitis (PVNS) found in a cadaver. PVNS is a rare overgrowth of the synovium that lines joints. The researchers dissected the knees and shoulders of a cadaver that had been previously diagnosed with arthritis. They found evidence of PVNS, including pigmented nodules. Photos were taken to document the progression of PVNS from early pigmentation to mature nodule formation. Studying PVNS in cadavers provides useful models for understanding arthritic diseases.
Presentation1, radiological imaging of diabetic foor and charcot joint.Abdellah Nazeer
This document discusses radiological imaging techniques for evaluating diabetic foot complications such as infection and Charcot foot. It provides examples of MRI, CT, ultrasound, bone scintigraphy, and PET/CT images showing osteomyelitis, soft tissue infections, and Charcot arthropathy in diabetic feet. MRI is highlighted as the most useful imaging method for diagnosing osteomyelitis, while PET/CT can help distinguish osteomyelitis from Charcot disease.
This document discusses seronegative spondyloarthropathies, which are musculoskeletal syndromes linked by common features including being negative for rheumatoid factor and often involving the axial skeleton. There are five main subgroups, including ankylosing spondylitis, psoriatic arthritis, reactive arthritis, enteropathic arthritis, and undifferentiated spondyloarthritis. The document then provides details on the clinical presentation and radiographic findings for each of these three conditions in three sample patient cases.
The document discusses patellofemoral osteoarthritis (OA) and how it differs from tibiofemoral OA. It begins by describing how MRI has provided new insights into patellofemoral OA by enabling direct visualization of knee joint structures. While tibiofemoral and patellofemoral OA share some characteristics, they also have key differences. Specifically, patellofemoral OA presents more with activities involving the patella like squatting or stairs, while tibiofemoral OA pain is more from activities with axial loading. Treatment also differs between the compartments. MRI is now able to detect early cartilage changes associated with OA onset and progression in both compartments.
Osteoid osteoma is among the commonest bone tumors, primarily affecting young subjects. Often localized in the diaphysis cortex of long bones, the disease has a well-described symptomatology and imagery of choice for diagnosis. When in a different location, the diagnosis is less evident. We describe a case herein of an intra-articular osteoid osteoma of the hip misdiagnosed as a femoro-acetabular impingement and treated by means of hip arthroscopy.
MRI is useful for assessing soft tissues, vessels, and sometimes bones in the foot, which is a complex structure with over 26 bones, muscles, and ligaments. The document describes several cases where MRI provided valuable information: a case of suspected cuboid pathology where MRI found peroneus longus tendonitis; a non-healing foot ulcer where MRI discovered a foreign body; a case of plantar fasciitis where MRI is not usually needed but can detect fascia rupture; and a diabetic foot where MRI demonstrated osteomyelitis and septic arthritis. The document emphasizes that MRI is effective for evaluating diabetes-related foot infections and distinguishing neuropathic from infectious causes.
This document contains abstracts from presentations at the 29th Annual Northeast Regional Scientific Meeting. The abstracts describe several studies involving nuclear imaging techniques:
1. A study evaluating the reproducibility of quantitative measurements from FDG PET and gallium scans in distinguishing between interstitial nephritis and acute tubular necrosis in rats. It found the measurements to be highly reproducible.
2. A case report describing how SPECT/CT imaging with indium-111 labeled white blood cells revealed unsuspected pulmonary septic emboli in a patient with infected hemodialysis access.
3. A case report where bone SPECT/CT identified an acute pelvic fracture that was missed on other imaging in a patient
Professor of Radiology and Medicine
Vice Chair, Academic Affairs
Assistant Dean of Diversity
Director, Quantitative Imaging Center (QIC)
Boston University School of Medicine, Boston, MA
This document summarizes a study of Pigmented Villonodular Synovitis (PVNS) found in a cadaver. PVNS is a rare overgrowth of the synovium that lines joints. The researchers dissected the knees and shoulders of a cadaver that had been previously diagnosed with arthritis. They found evidence of PVNS, including pigmented nodules. Photos were taken to document the progression of PVNS from early pigmentation to mature nodule formation. Studying PVNS in cadavers provides useful models for understanding arthritic diseases.
Presentation1, radiological imaging of diabetic foor and charcot joint.Abdellah Nazeer
This document discusses radiological imaging techniques for evaluating diabetic foot complications such as infection and Charcot foot. It provides examples of MRI, CT, ultrasound, bone scintigraphy, and PET/CT images showing osteomyelitis, soft tissue infections, and Charcot arthropathy in diabetic feet. MRI is highlighted as the most useful imaging method for diagnosing osteomyelitis, while PET/CT can help distinguish osteomyelitis from Charcot disease.
This document discusses seronegative spondyloarthropathies, which are musculoskeletal syndromes linked by common features including being negative for rheumatoid factor and often involving the axial skeleton. There are five main subgroups, including ankylosing spondylitis, psoriatic arthritis, reactive arthritis, enteropathic arthritis, and undifferentiated spondyloarthritis. The document then provides details on the clinical presentation and radiographic findings for each of these three conditions in three sample patient cases.
The document discusses patellofemoral osteoarthritis (OA) and how it differs from tibiofemoral OA. It begins by describing how MRI has provided new insights into patellofemoral OA by enabling direct visualization of knee joint structures. While tibiofemoral and patellofemoral OA share some characteristics, they also have key differences. Specifically, patellofemoral OA presents more with activities involving the patella like squatting or stairs, while tibiofemoral OA pain is more from activities with axial loading. Treatment also differs between the compartments. MRI is now able to detect early cartilage changes associated with OA onset and progression in both compartments.
Osteoid osteoma is among the commonest bone tumors, primarily affecting young subjects. Often localized in the diaphysis cortex of long bones, the disease has a well-described symptomatology and imagery of choice for diagnosis. When in a different location, the diagnosis is less evident. We describe a case herein of an intra-articular osteoid osteoma of the hip misdiagnosed as a femoro-acetabular impingement and treated by means of hip arthroscopy.
MRI is useful for assessing soft tissues, vessels, and sometimes bones in the foot, which is a complex structure with over 26 bones, muscles, and ligaments. The document describes several cases where MRI provided valuable information: a case of suspected cuboid pathology where MRI found peroneus longus tendonitis; a non-healing foot ulcer where MRI discovered a foreign body; a case of plantar fasciitis where MRI is not usually needed but can detect fascia rupture; and a diabetic foot where MRI demonstrated osteomyelitis and septic arthritis. The document emphasizes that MRI is effective for evaluating diabetes-related foot infections and distinguishing neuropathic from infectious causes.
This document contains abstracts from presentations at the 29th Annual Northeast Regional Scientific Meeting. The abstracts describe several studies involving nuclear imaging techniques:
1. A study evaluating the reproducibility of quantitative measurements from FDG PET and gallium scans in distinguishing between interstitial nephritis and acute tubular necrosis in rats. It found the measurements to be highly reproducible.
2. A case report describing how SPECT/CT imaging with indium-111 labeled white blood cells revealed unsuspected pulmonary septic emboli in a patient with infected hemodialysis access.
3. A case report where bone SPECT/CT identified an acute pelvic fracture that was missed on other imaging in a patient
Background:
The anterolateral ligament (ALL) is a true well-defined ligament in the knee first described in 1879 by Segond. After the work of Claes et al., several studies were conducted about biomechanics and its role in stability of the knee. The anatomical existence of the ALL has been studied by and various radiographic diagnostic modalities and in cadavers. It originates from lateral femoral epicondyle and is inserted between Gerdy’s tubercle and the fibular head. There has been controversy about the existence of ALL in pediatric patients. The aim of this work was to confirm the presence of ALL in pediatric patients by using MRI.
Materials and Methods:
We reviewed the knee MRI scans of 100 pediatric patients (ages between one and 12 yr) who had no knee injury or congenital deformity and had been evaluated by an expert radiologist.
Results:
The ALL was detected in 90% of the pediatric patients with the use of MRI.
Conclusions:
The main finding of this study was that ALL can be seen in pediatric patients using MRI. Despite numerous studies, additional research is needed to further define the role of the ALL in knee function.
Level of Evidence:
Level IV.
The document summarizes diagnostic radiology findings of musculoskeletal infectious diseases and joint disorders. It describes imaging features of acute and chronic osteomyelitis caused by bacteria and tuberculosis including bone destruction, periosteal reaction, and abscess formation. It also compares findings of pyogenic and tuberculous arthritis, noting tuberculosis involves bone margins and causes osteoporosis while pyogenic arthritis affects weight-bearing areas and leads to more bone destruction and sclerosis. Common joint disorders like osteoarthritis, ankylosis, and dislocations are outlined.
Imaging of foot in non trauma and non neoplastic diseasesShail Padmani
The document discusses the radiologic evaluation of the foot. It begins by describing the complex anatomy of the foot and various pathologies that can occur. It then discusses the sequence of ossification in the foot bones during fetal development. Various imaging modalities for evaluating the foot are described including radiography, ultrasound, CT, and MRI. Common congenital variants, abnormalities, tendon pathologies and other conditions involving the foot that can be assessed with imaging are outlined.
Osteoarthritis is defined by the presence of joint damage and is most commonly diagnosed through x-ray imaging. While many older individuals have radiographic evidence of osteoarthritis, only a portion experience joint pain and symptoms. The most frequently affected joints are the spine, fingers, knees and hips. Standard x-rays can reveal signs like reduced joint space, bone spurs and cysts. MRI may provide additional details on cartilage damage and other abnormalities but is generally not needed for routine osteoarthritis diagnosis and management.
The value of clinical knowledge in understanding pathological findings in Ang...University of Derby
Palaeopathology is about understanding what you are looking at and how it relates to actual clinical conditions. It is often only by having an awareness of the clinical condition that you can come to a diagnosis when viewing osteological features.
Using examples from clinical photography, specifically orthopaedics, examples of pathology from the Anglo-Saxon cemetery in Little Chester, Derby and papers published, in many and varied journals, by Calvin Wells it is possible to see the importance of viewing palaeopathology from a clinician’s perspective.
Population level analysis, for example the quantification of osteoarthritis (OA) in a particular area or cemetery, gives information about the frequency of occurrence of specific traits associated with OA. What it doesn’t do is give us a picture of actual diagnoses. Under a general category of OA of the knee you could have individuals with varus or valgus deformities, eburnation of the tibial plateau and femoral condyles and accompanying osteophytes through to variations in the patella-femoral joint e.g. subluxation, lateral patella maltracking and patella alta.
Individual diagnoses though leading to short simple papers or a series of case studies can be equally valuable in understanding how our ancestors lived. Through looking at actual diagnoses we can link how people lived with specific increases or decreases in clinical conditions that could lead to ways of decreasing the impact of OA in modern populations.
In the presentation, I discussed new concepts in OA pathogenesis and identified possible targets of treatment. This was followed by a review of new treatment options for osteoarthritis. Presented during the Joint RA OA SIG Symposium at the F1 Hotel last 28 November 2014.
The role of radiation diagnostic methods in pathological changes of the hip j...SubmissionResearchpa
Endoprosthesis replacement-operational treatment of diseases and damages of hip joint. The problem of prevention of complications and their negative effects is extremely actual today. However the role of different beam techniques in identification of adverse effects and complications of endoprosthesis replacement of joints is studied insufficiently. Results of clinic and diagnostic and beam researches of 40 patients with pathology of hip joint are analyzed. The used beam methods of research - roentgenography, multispiral computed tomography. At presurgical stage the main objective was detection of pathology of joint, definition of indications and planning of operative measure. Situation and relationship of components of endoprosthesis, condition of bone tissue, and also bone cement round cup and leg of prosthesis were key parameters of radiological assessment of outcomes of endoprosthesis replacement. Complex use of radiological techniques (roentgenography and spiral computed tomography) allows to specify and add semiotics of changes of bone tissue at the level of acetabular hollow and proximal department of femur after endoprosthesis replacement. by Janibekov J. J 2020. The role of radiation diagnostic methods in pathological changes of the hip joint before and after endoprosthetics. International Journal on Integrated Education. 3, 11 (Dec. 2020), 203-205. DOI:https://doi.org/10.31149/ijie.v3i12.918. https://journals.researchparks.org/index.php/IJIE/article/view/918/866 https://journals.researchparks.org/index.php/IJIE/article/view/918
This document discusses axial spondyloarthritis (SpA) and non-radiographic axial SpA (nr-axSpA) in South East Asia. It outlines epidemiological studies that show the prevalence of SpA is around 1% in China and other Asian countries. There are often long delays in diagnosis of over 5 years due to lack of awareness among general practitioners. Once referred to rheumatologists, TNF inhibitors are not always accessible or affordable treatments due to cost and safety concerns, especially regarding tuberculosis. The document promotes educating clinicians on SpA criteria and referral pathways, as well as improving access to treatments, to help address the significant health burden caused by delayed diagnosis and inadequate management of SpA patients in Asia.
Abstract
Frequent Knee Locking is an incapacitating condition that requires a thorough clinical, radiological and arthroscopic evaluation. The common causes are meniscal injury followed by torn anterior cruciate ligament and osteochondral loose bodies in the joint space. Our case describes an unusual case of frequent left knee locking. After clinical and radiological examinations the provisional diagnoses of medial meniscus tear was done. A diagnostic arthroscopy of the left knee revealed normal meniscus, cruciates and a medial patello femoral plica slipping into the patellofemoral joint causing the locking sensation. The plica was resected. At 6 month follow up there is no recurrence of symptoms.
Evidence Based Practice in Medical Imaging- Ankylosing SpondylitisNoor Farahuda
This presentation is about evidence-based practice in medical imaging for a particular disease, which is the Ankylosing Spondylitis. It is actually focusing on the imaging modalities that have been used for diagnose the disease and the appearances of the disease on the image of the modalities.
Open debridement and radiocapitellar replacement in primary and post-traumati...Alberto Mantovani
Background: Postmortem and clinical studies have shown an early and prevalent involvement of the radiohumeral
joint in primary and secondary arthritis of the elbow. The lateral resurfacing elbow (LRE) prosthesis
has recently been developed for the treatment of lateral elbow arthritis. However, few data have been
published on LRE results.
Materials and methods: A prospective multicenter study was designed to assess LRE preliminary results.
There were 20 patients (average age, 55 years). Preoperative diagnosis were primary osteoarthritis in 11
and post-traumatic osteoarthritis in 9. All patients underwent open debridement and LRE prosthesis.
Patients were evaluated preoperatively and postoperatively with the Mayo Elbow Performance Score
(MEPS), modified American Shoulder Elbow Surgeons (m-ASES) elbow assessment, and the Quick
Disabilities of the Arm, Shoulder and Hand (Quick-DASH). Mean follow-up was 22.6 months.
Results: At the last follow-up, the mean improvement of MEPS and m-ASES was 35 (P ¼ .001) and 34
(P ¼ .001) respectively; the average Quick DASH decreased by 29 (P ¼ .001). Average range of motion
was improved by 35 (P ¼.001). MEPI results were excellent in 12 patients, good in 2, and fair and poor in
3 each. Mild overstuffing was observed in 5 patients, and an implant malpositioning in 3. The implant
survival rate was 100%.
Conclusion: LRE showed promising results in this prospective investigation. Most patients had an
uneventful postoperative course and have shown a painless elbow joint, with satisfactory functional
recovery at short-term follow-up. Further studies with longer follow-up are warranted.
Comparison of 3 d shoulder complex kinematic part 1Satoshi Kajiyama
This study compared shoulder complex kinematics between individuals with and without shoulder pain. Transcortical bone pins were inserted into the clavicle, scapula, and humerus of 12 asymptomatic and 10 symptomatic individuals. Angular positions of the sternoclavicular, acromioclavicular, and scapulothoracic joints were measured during shoulder motions. Differences were found between groups for sternoclavicular and scapulothoracic joint positions, with symptomatic individuals demonstrating less sternoclavicular posterior rotation and scapulothoracic upward rotation. However, the magnitude of differences was small and clinical implications are not fully understood.
The document discusses the role of magnetic resonance imaging (MRI) in assessing and monitoring rheumatoid arthritis (RA). It covers how MRI can help with early diagnosis of RA, predict joint damage, and serve as an outcome measure for treatment. Key findings by MRI include synovitis, tenosynovitis, bone erosions, bone marrow edema, and cartilage loss. Scoring systems like RAMRIS provide standardized ways to interpret MRI scans and track changes in RA pathology over time. MRI is more sensitive than x-rays and can detect signs of inflammation and damage earlier in the disease course.
This technical note describes an arthroscopic technique for addressing both a rotator cuff tear and a cyst within the greater tuberosity. The authors present a 1-step procedure using porous, resorbable scaffolds to fill the cyst defect at the time of rotator cuff repair. The cyst is thoroughly debrided and a matching implant is placed flush with the bone. Standard rotator cuff repair is then performed. In a 57-year-old patient, MRI at 6 months showed healing of both the cyst and rotator cuff. The technique provides an option for surgeons facing this clinical challenge with minimal additional time or morbidity.
This technical note describes an arthroscopic technique for addressing both a rotator cuff tear and a cyst within the greater tuberosity. The authors debrided the cyst cavity to create a socket, then implanted a resorbable scaffold to provide structure and promote bone ingrowth. This allowed the standard rotator cuff repair to then be performed. MRI at 6 months showed healing of both the cyst and rotator cuff tear. The technique provides a readily available option for surgeons facing this clinical challenge.
Four Corner Fusion is a surgical procedure used to treat carpal instability and arthritis. It involves fusing together the four small carpal bones (scaphoid, lunate, triquetrum, and pisiform) through bone preparation, temporary fixation with K-wires, and permanent fixation with a plate and screws. The procedure aims to reduce pain, maintain range of motion and grip strength, and allow activities of daily living. Contraindications include a stiff wrist, radiolunate arthritis, or erosive arthropathy, which may be better treated with proximal row carpectomy.
PDF Disfunción sacroiliaca evaluación y manejoFtAndres
This article reviews sacroiliac joint dysfunction as a source of low back and pelvic pain. There are no widely accepted guidelines for diagnosing or treating sacroiliac joint dysfunction due to variability in symptoms, limited objective testing options, and incomplete understanding of biomechanics. Pain from the sacroiliac joint can radiate to the buttocks, groin, and lower limbs in various patterns. The most reliable diagnostic technique is pain relief following local anesthetic injection into the joint. Most patients respond to non-operative treatment, while those who do not may be candidates for operative stabilization of the joint.
Studying relation between sitting position and knee osteoarthritiiosrjce
Osteoarthritis (OA) of the knee is the most common form of arthritis and leads to more activity
limitations (e.g., disability in walking and stair climbing) than any other disease, especially in the elderly. The
aim of this study was to clarify the relationship between the sitting position and knee osteoarthritis. The study
involved fat males of knee pain and clinical diagnosis of early knee osteoarthritis this research is applied and
the research method is "descriptive-correlative". In order to collecting data was used questionnaire tool. Also,
in order to analyzing data was used statistical method such as Pierson coefficient and Chi-squared test. Data is
analyzed from both descriptive and inferential statistics. Descriptive statistics and graphs on the table will
describe the characteristics of the study sample. The researcher to analyze the hypotheses used Chi-square
method. The statistical society is Osteoarthritis disease males.
1) Osteoarthritis is the sixth leading cause of disability worldwide and is a major cause of work limitations and early retirement in those over 60 years old.
2) The socioeconomic burden of joint replacement surgeries for symptomatic osteoarthritis in Italy is significant.
3) Osteoarthritis has both primary and secondary forms that can be caused by factors like joint trauma, developmental abnormalities, biomechanical disturbances, and genetic or metabolic diseases.
- Ankylosing spondylitis (AS) is a chronic inflammatory disease that primarily affects the spine and sacroiliac joints, causing back pain and spinal stiffness. It is associated with the HLA-B27 gene and sometimes follows bacterial infections.
- Symptoms include limited spinal mobility, buttocks and hip pain, and inflammation of tendon attachments or entire fingers. It typically presents in individuals younger than 40 and is more common in men.
- Treatment involves exercise, medications like NSAIDs and TNF inhibitors, and surgery for joint replacement or spinal issues. The goals are to reduce pain, improve mobility, and prevent complications.
Background:
The anterolateral ligament (ALL) is a true well-defined ligament in the knee first described in 1879 by Segond. After the work of Claes et al., several studies were conducted about biomechanics and its role in stability of the knee. The anatomical existence of the ALL has been studied by and various radiographic diagnostic modalities and in cadavers. It originates from lateral femoral epicondyle and is inserted between Gerdy’s tubercle and the fibular head. There has been controversy about the existence of ALL in pediatric patients. The aim of this work was to confirm the presence of ALL in pediatric patients by using MRI.
Materials and Methods:
We reviewed the knee MRI scans of 100 pediatric patients (ages between one and 12 yr) who had no knee injury or congenital deformity and had been evaluated by an expert radiologist.
Results:
The ALL was detected in 90% of the pediatric patients with the use of MRI.
Conclusions:
The main finding of this study was that ALL can be seen in pediatric patients using MRI. Despite numerous studies, additional research is needed to further define the role of the ALL in knee function.
Level of Evidence:
Level IV.
The document summarizes diagnostic radiology findings of musculoskeletal infectious diseases and joint disorders. It describes imaging features of acute and chronic osteomyelitis caused by bacteria and tuberculosis including bone destruction, periosteal reaction, and abscess formation. It also compares findings of pyogenic and tuberculous arthritis, noting tuberculosis involves bone margins and causes osteoporosis while pyogenic arthritis affects weight-bearing areas and leads to more bone destruction and sclerosis. Common joint disorders like osteoarthritis, ankylosis, and dislocations are outlined.
Imaging of foot in non trauma and non neoplastic diseasesShail Padmani
The document discusses the radiologic evaluation of the foot. It begins by describing the complex anatomy of the foot and various pathologies that can occur. It then discusses the sequence of ossification in the foot bones during fetal development. Various imaging modalities for evaluating the foot are described including radiography, ultrasound, CT, and MRI. Common congenital variants, abnormalities, tendon pathologies and other conditions involving the foot that can be assessed with imaging are outlined.
Osteoarthritis is defined by the presence of joint damage and is most commonly diagnosed through x-ray imaging. While many older individuals have radiographic evidence of osteoarthritis, only a portion experience joint pain and symptoms. The most frequently affected joints are the spine, fingers, knees and hips. Standard x-rays can reveal signs like reduced joint space, bone spurs and cysts. MRI may provide additional details on cartilage damage and other abnormalities but is generally not needed for routine osteoarthritis diagnosis and management.
The value of clinical knowledge in understanding pathological findings in Ang...University of Derby
Palaeopathology is about understanding what you are looking at and how it relates to actual clinical conditions. It is often only by having an awareness of the clinical condition that you can come to a diagnosis when viewing osteological features.
Using examples from clinical photography, specifically orthopaedics, examples of pathology from the Anglo-Saxon cemetery in Little Chester, Derby and papers published, in many and varied journals, by Calvin Wells it is possible to see the importance of viewing palaeopathology from a clinician’s perspective.
Population level analysis, for example the quantification of osteoarthritis (OA) in a particular area or cemetery, gives information about the frequency of occurrence of specific traits associated with OA. What it doesn’t do is give us a picture of actual diagnoses. Under a general category of OA of the knee you could have individuals with varus or valgus deformities, eburnation of the tibial plateau and femoral condyles and accompanying osteophytes through to variations in the patella-femoral joint e.g. subluxation, lateral patella maltracking and patella alta.
Individual diagnoses though leading to short simple papers or a series of case studies can be equally valuable in understanding how our ancestors lived. Through looking at actual diagnoses we can link how people lived with specific increases or decreases in clinical conditions that could lead to ways of decreasing the impact of OA in modern populations.
In the presentation, I discussed new concepts in OA pathogenesis and identified possible targets of treatment. This was followed by a review of new treatment options for osteoarthritis. Presented during the Joint RA OA SIG Symposium at the F1 Hotel last 28 November 2014.
The role of radiation diagnostic methods in pathological changes of the hip j...SubmissionResearchpa
Endoprosthesis replacement-operational treatment of diseases and damages of hip joint. The problem of prevention of complications and their negative effects is extremely actual today. However the role of different beam techniques in identification of adverse effects and complications of endoprosthesis replacement of joints is studied insufficiently. Results of clinic and diagnostic and beam researches of 40 patients with pathology of hip joint are analyzed. The used beam methods of research - roentgenography, multispiral computed tomography. At presurgical stage the main objective was detection of pathology of joint, definition of indications and planning of operative measure. Situation and relationship of components of endoprosthesis, condition of bone tissue, and also bone cement round cup and leg of prosthesis were key parameters of radiological assessment of outcomes of endoprosthesis replacement. Complex use of radiological techniques (roentgenography and spiral computed tomography) allows to specify and add semiotics of changes of bone tissue at the level of acetabular hollow and proximal department of femur after endoprosthesis replacement. by Janibekov J. J 2020. The role of radiation diagnostic methods in pathological changes of the hip joint before and after endoprosthetics. International Journal on Integrated Education. 3, 11 (Dec. 2020), 203-205. DOI:https://doi.org/10.31149/ijie.v3i12.918. https://journals.researchparks.org/index.php/IJIE/article/view/918/866 https://journals.researchparks.org/index.php/IJIE/article/view/918
This document discusses axial spondyloarthritis (SpA) and non-radiographic axial SpA (nr-axSpA) in South East Asia. It outlines epidemiological studies that show the prevalence of SpA is around 1% in China and other Asian countries. There are often long delays in diagnosis of over 5 years due to lack of awareness among general practitioners. Once referred to rheumatologists, TNF inhibitors are not always accessible or affordable treatments due to cost and safety concerns, especially regarding tuberculosis. The document promotes educating clinicians on SpA criteria and referral pathways, as well as improving access to treatments, to help address the significant health burden caused by delayed diagnosis and inadequate management of SpA patients in Asia.
Abstract
Frequent Knee Locking is an incapacitating condition that requires a thorough clinical, radiological and arthroscopic evaluation. The common causes are meniscal injury followed by torn anterior cruciate ligament and osteochondral loose bodies in the joint space. Our case describes an unusual case of frequent left knee locking. After clinical and radiological examinations the provisional diagnoses of medial meniscus tear was done. A diagnostic arthroscopy of the left knee revealed normal meniscus, cruciates and a medial patello femoral plica slipping into the patellofemoral joint causing the locking sensation. The plica was resected. At 6 month follow up there is no recurrence of symptoms.
Evidence Based Practice in Medical Imaging- Ankylosing SpondylitisNoor Farahuda
This presentation is about evidence-based practice in medical imaging for a particular disease, which is the Ankylosing Spondylitis. It is actually focusing on the imaging modalities that have been used for diagnose the disease and the appearances of the disease on the image of the modalities.
Open debridement and radiocapitellar replacement in primary and post-traumati...Alberto Mantovani
Background: Postmortem and clinical studies have shown an early and prevalent involvement of the radiohumeral
joint in primary and secondary arthritis of the elbow. The lateral resurfacing elbow (LRE) prosthesis
has recently been developed for the treatment of lateral elbow arthritis. However, few data have been
published on LRE results.
Materials and methods: A prospective multicenter study was designed to assess LRE preliminary results.
There were 20 patients (average age, 55 years). Preoperative diagnosis were primary osteoarthritis in 11
and post-traumatic osteoarthritis in 9. All patients underwent open debridement and LRE prosthesis.
Patients were evaluated preoperatively and postoperatively with the Mayo Elbow Performance Score
(MEPS), modified American Shoulder Elbow Surgeons (m-ASES) elbow assessment, and the Quick
Disabilities of the Arm, Shoulder and Hand (Quick-DASH). Mean follow-up was 22.6 months.
Results: At the last follow-up, the mean improvement of MEPS and m-ASES was 35 (P ¼ .001) and 34
(P ¼ .001) respectively; the average Quick DASH decreased by 29 (P ¼ .001). Average range of motion
was improved by 35 (P ¼.001). MEPI results were excellent in 12 patients, good in 2, and fair and poor in
3 each. Mild overstuffing was observed in 5 patients, and an implant malpositioning in 3. The implant
survival rate was 100%.
Conclusion: LRE showed promising results in this prospective investigation. Most patients had an
uneventful postoperative course and have shown a painless elbow joint, with satisfactory functional
recovery at short-term follow-up. Further studies with longer follow-up are warranted.
Comparison of 3 d shoulder complex kinematic part 1Satoshi Kajiyama
This study compared shoulder complex kinematics between individuals with and without shoulder pain. Transcortical bone pins were inserted into the clavicle, scapula, and humerus of 12 asymptomatic and 10 symptomatic individuals. Angular positions of the sternoclavicular, acromioclavicular, and scapulothoracic joints were measured during shoulder motions. Differences were found between groups for sternoclavicular and scapulothoracic joint positions, with symptomatic individuals demonstrating less sternoclavicular posterior rotation and scapulothoracic upward rotation. However, the magnitude of differences was small and clinical implications are not fully understood.
The document discusses the role of magnetic resonance imaging (MRI) in assessing and monitoring rheumatoid arthritis (RA). It covers how MRI can help with early diagnosis of RA, predict joint damage, and serve as an outcome measure for treatment. Key findings by MRI include synovitis, tenosynovitis, bone erosions, bone marrow edema, and cartilage loss. Scoring systems like RAMRIS provide standardized ways to interpret MRI scans and track changes in RA pathology over time. MRI is more sensitive than x-rays and can detect signs of inflammation and damage earlier in the disease course.
This technical note describes an arthroscopic technique for addressing both a rotator cuff tear and a cyst within the greater tuberosity. The authors present a 1-step procedure using porous, resorbable scaffolds to fill the cyst defect at the time of rotator cuff repair. The cyst is thoroughly debrided and a matching implant is placed flush with the bone. Standard rotator cuff repair is then performed. In a 57-year-old patient, MRI at 6 months showed healing of both the cyst and rotator cuff. The technique provides an option for surgeons facing this clinical challenge with minimal additional time or morbidity.
This technical note describes an arthroscopic technique for addressing both a rotator cuff tear and a cyst within the greater tuberosity. The authors debrided the cyst cavity to create a socket, then implanted a resorbable scaffold to provide structure and promote bone ingrowth. This allowed the standard rotator cuff repair to then be performed. MRI at 6 months showed healing of both the cyst and rotator cuff tear. The technique provides a readily available option for surgeons facing this clinical challenge.
Four Corner Fusion is a surgical procedure used to treat carpal instability and arthritis. It involves fusing together the four small carpal bones (scaphoid, lunate, triquetrum, and pisiform) through bone preparation, temporary fixation with K-wires, and permanent fixation with a plate and screws. The procedure aims to reduce pain, maintain range of motion and grip strength, and allow activities of daily living. Contraindications include a stiff wrist, radiolunate arthritis, or erosive arthropathy, which may be better treated with proximal row carpectomy.
PDF Disfunción sacroiliaca evaluación y manejoFtAndres
This article reviews sacroiliac joint dysfunction as a source of low back and pelvic pain. There are no widely accepted guidelines for diagnosing or treating sacroiliac joint dysfunction due to variability in symptoms, limited objective testing options, and incomplete understanding of biomechanics. Pain from the sacroiliac joint can radiate to the buttocks, groin, and lower limbs in various patterns. The most reliable diagnostic technique is pain relief following local anesthetic injection into the joint. Most patients respond to non-operative treatment, while those who do not may be candidates for operative stabilization of the joint.
Studying relation between sitting position and knee osteoarthritiiosrjce
Osteoarthritis (OA) of the knee is the most common form of arthritis and leads to more activity
limitations (e.g., disability in walking and stair climbing) than any other disease, especially in the elderly. The
aim of this study was to clarify the relationship between the sitting position and knee osteoarthritis. The study
involved fat males of knee pain and clinical diagnosis of early knee osteoarthritis this research is applied and
the research method is "descriptive-correlative". In order to collecting data was used questionnaire tool. Also,
in order to analyzing data was used statistical method such as Pierson coefficient and Chi-squared test. Data is
analyzed from both descriptive and inferential statistics. Descriptive statistics and graphs on the table will
describe the characteristics of the study sample. The researcher to analyze the hypotheses used Chi-square
method. The statistical society is Osteoarthritis disease males.
1) Osteoarthritis is the sixth leading cause of disability worldwide and is a major cause of work limitations and early retirement in those over 60 years old.
2) The socioeconomic burden of joint replacement surgeries for symptomatic osteoarthritis in Italy is significant.
3) Osteoarthritis has both primary and secondary forms that can be caused by factors like joint trauma, developmental abnormalities, biomechanical disturbances, and genetic or metabolic diseases.
- Ankylosing spondylitis (AS) is a chronic inflammatory disease that primarily affects the spine and sacroiliac joints, causing back pain and spinal stiffness. It is associated with the HLA-B27 gene and sometimes follows bacterial infections.
- Symptoms include limited spinal mobility, buttocks and hip pain, and inflammation of tendon attachments or entire fingers. It typically presents in individuals younger than 40 and is more common in men.
- Treatment involves exercise, medications like NSAIDs and TNF inhibitors, and surgery for joint replacement or spinal issues. The goals are to reduce pain, improve mobility, and prevent complications.
multiple level spondylodiscitis in neurobrucllosis: int jr of medicineSachin Adukia
Multiple level spondylodiscitis with presacral abscess in spinal brucellosis: a rare presentation
A 56-year-old male farmer in India presented with lower back pain and weakness in his legs for 9 weeks. MRI revealed multi-level infective spondylodiscitis and a prevertebral sacral abscess. Blood culture grew Brucella melitensis after 8 days. Treatment was modified to a 12-month triple antibiotic therapy. Spinal brucellosis should be considered for those with back pain in endemic areas, as timely diagnosis and appropriate treatment is important.
The document discusses sacroiliac joint pain, which accounts for 15-30% of all lower back pain cases. It can be difficult to diagnose due to the complex anatomy of the sacroiliac joint. Physical examination maneuvers like Patrick's test and resisted abduction can help identify sacroiliac joint pain, but diagnostic blocks provide the most accurate confirmation. Common treatments include steroid injections into the joint, followed by options like nerve blocks, radiofrequency ablation, or surgery if more invasive treatments are needed.
In this study of 277 post-menopausal women, the researchers found:
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A Large Intra-Articular Ossicle in the Knee Joint-A Rare Occurrence_Crimson P...CrimsonPublishersAICS
This document presents a case report of a rare occurrence of a large intra-articular ossicle in the knee joint of a 14-year-old male. Magnetic resonance imaging found a large ossicle impinging on the anterior cruciate ligament, causing lifting of the ligament anteriorly and laterally. Intra-articular ossicles in the knee are uncommon but can grow to a significant size, as seen in this case, producing mass effect and clinically mimicking an ACL injury. The etiology of intra-articular ossicles is unclear but may be congenital, traumatic, or degenerative in origin.
The document discusses spinal involvement in crystal-related diseases, focusing on gout. Spine involvement in gout is uncommon but can occur in cases of severe tophaceous gout. Symptoms may be asymptomatic initially or include acute or chronic back pain and nerve compression. Diagnosis is made through identification of urate crystals via aspiration or biopsy of spinal lesions. Imaging such as CT, MRI can show erosions, tophi, and lesions affecting various spinal structures including intervertebral discs, facet joints, and ligaments. Spinal cord or cauda equina compression may occur due to large tophi. While back pain is present in about half of cases, spinal involvement in gout is often missed likely due to
This document discusses a 48-year-old woman presenting with neck pain and right upper extremity symptoms two years following an anterior cervical discectomy and fusion (ACDF) at C4-C7. Imaging shows a nonunion at C6-C7 with graft collapse and anteriorly migrated screws. The patient's options for revision surgery are discussed, including an anterior-only, posterior-only, or combined anterior-posterior procedure. Risk factors for ACDF nonunion and strategies for bone grafting and fixation are also reviewed.
This study aims to investigate the relationship between posture, spinal balance, muscle fatigue, and symptoms in patients with lumbar spinal stenosis before and one year after surgery. Over 120 patients will undergo clinical assessments, questionnaires, radiological imaging, biomechanical testing, and activity monitoring at baseline, 6 months post-op, and 1 year post-op. Biomechanical testing will involve measuring posture and gait with and without induced paraspinal muscle fatigue. The study aims to determine if outcomes correlate with severity of stenosis, muscle degeneration, compensation strategies, and changes after surgery. Results may help understand the condition and guide treatment and rehabilitation.
Nuclear medicine in musculoskeletal disordersfatmahoceny
This document discusses nuclear medicine techniques for evaluating musculoskeletal disorders like rheumatoid arthritis. It provides an overview of normal bone scintigraphy patterns and discusses how nuclear medicine can detect functional changes in RA before structural damage occurs. Specifically, it notes that three-phase bone scintigraphy and SPECT are sensitive for detecting early RA abnormalities and monitoring treatment response. Positron emission tomography using FDG can also quantify joint inflammation and correlate with disease activity measures. Nuclear medicine thus provides functional imaging that complements anatomical imaging for evaluating musculoskeletal diseases.
the presentation gives a detail information about the seronegative spondyloarthropathy. this ppt also provide recent evidences to frame the rehab protocol.
Spondyloarthropathy (SpA) is a chronic inflammatory condition that can cause disabling symptoms. It includes disorders like ankylosing spondylitis (AS), psoriatic arthritis, and arthritis related to inflammatory bowel disease. Many patients have mild disease controlled with NSAIDs, but some experience poor prognosis with persistent active disease even when treated. Biologic therapies targeting TNF-α have shown promising results for these patients. SpA is characterized by axial or peripheral joint involvement, enthesitis, and potential extra-articular manifestations often associated with the HLA-B27 genetic factor.
This document discusses avascular necrosis of the femoral head, also known as osteonecrosis. It begins by providing a brief history and definitions. It then discusses the blood supply of the femoral head and covers traumatic vs. non-traumatic causes. Risk factors for atraumatic osteonecrosis like corticosteroids, alcohol abuse, smoking, and others are outlined. The pathophysiology section explores theories of arterial occlusion, fat emboli, and increased bone marrow pressure as causes. Signs and symptoms, diagnostic imaging methods, staging classifications, and non-operative and operative treatment options are summarized.
This document discusses patterns, variants, artifacts, and pitfalls seen on conventional radionuclide bone imaging and SPECT/CT scans. It notes that bone scans have high sensitivity but variable specificity. It describes common normal variants seen in the skull, sternum, vertebrae and other bones that can mimic pathology. Knowing these variants is important to avoid misinterpretation of scans. The document also discusses how hybrid SPECT/CT imaging can help characterize indeterminate lesions seen on bone scans.
Quantitative analysis of patellar tendon size and structure in asymptomatic ...Medical_Lab
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This document discusses avascular necrosis of the femoral head, also known as osteonecrosis. It begins by defining avascular necrosis as a pathological process resulting from interrupted blood supply to the bone. It then covers the epidemiology, risk factors, imaging findings, staging systems, pathophysiology, and treatment options. The main treatment approaches discussed are non-operative options like restricted weight bearing, lipid lowering agents, and external modalities; as well as operative options like core decompression and various bone grafting procedures.
The document provides instructions for a task in CINAHL regarding ankle joint exploration, diagnosis and manipulative therapy. It includes searching by subject headings and free text, limiting to 2010 onwards and peer-reviewed articles. It details exporting references to Mendeley and creating a weekly alert to receive updates on the topic. The task is to be published on a blog along with the process.
This document describes conducting a search in the CINAHL database to find academic publications related to manual therapy, physical examination, and diagnosis of ankle injuries from 2010 onwards. It outlines developing search terms, performing both free-text and controlled vocabulary searches, applying filters, and exporting the results to Mendeley for citation management and weekly email alerts. Key steps included searching for terms like "musculoskeletal manipulations", "physical examination", and "ankle joint"; applying filters for academic publications from 2010 onward; conducting searches using descriptors; and creating a weekly search alert to share results.
Spontaneous osteonecrosis of the knee (SPONK) was first described in 1968, and most commonly affects the medial femoral condyle in older women through impaired blood supply. SPONK presents with sudden onset knee pain similar to a meniscal tear. Diagnosis is made through x-rays showing bone changes or MRI showing bone edema and articular surface involvement. Treatment options include conservative management with medications and weight reduction or surgical interventions like core decompression, bone grafting, or knee replacement for advanced arthritis. Early detection of SPONK is important as it can be cured without needing knee replacement.
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It is unclear whether the administration of radioiodine provides any benefit in low-risk cases after a complete surgical resection, and radioiodine is not recommended in patients with disease that is categorized as consisting of a tumor less than 1 cm in diameter and clinical stage N0. Therefore, radioiodine should be used with great care to minimize harm, administer the minimal amount of radioactivity, and involve the best tolerated methods.
There are many guidelines and recommendations suggesting ablation/therapy in Differentiated Thyroid Carcinoma. This presentation will be focused on the details of these recommendations and guidelines.
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Nano-gold for Cancer Therapy chemistry investigatory projectSIVAVINAYAKPK
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Cancer remains one of the leading causes of death worldwide, prompting the need for innovative treatment methods. Nanotechnology offers promising new approaches, including the use of gold nanoparticles (nanogold) for targeted cancer therapy. Nanogold particles possess unique physical and chemical properties that make them suitable for drug delivery, imaging, and photothermal therapy.
Co-Chairs, Val J. Lowe, MD, and Cyrus A. Raji, MD, PhD, prepared useful Practice Aids pertaining to Alzheimer’s disease for this CME/AAPA activity titled “Alzheimer’s Disease Case Conference: Gearing Up for the Expanding Role of Neuroradiology in Diagnosis and Treatment.” For the full presentation, downloadable Practice Aids, and complete CME/AAPA information, and to apply for credit, please visit us at https://bit.ly/3PvVY25. CME/AAPA credit will be available until June 28, 2025.
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Travel Clinic Cardiff: Health Advice for International TravelersNX Healthcare
Travel Clinic Cardiff offers comprehensive travel health services, including vaccinations, travel advice, and preventive care for international travelers. Our expert team ensures you are well-prepared and protected for your journey, providing personalized consultations tailored to your destination. Conveniently located in Cardiff, we help you travel with confidence and peace of mind. Visit us: www.nxhealthcare.co.uk
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Test bank for karp s cell and molecular biology 9th edition by gerald karp.pdfrightmanforbloodline
Test bank for karp s cell and molecular biology 9th edition by gerald karp.pdf
Test bank for karp s cell and molecular biology 9th edition by gerald karp.pdf
Test bank for karp s cell and molecular biology 9th edition by gerald karp.pdf
- Video recording of this lecture in English language: https://youtu.be/Pt1nA32sdHQ
- Video recording of this lecture in Arabic language: https://youtu.be/uFdc9F0rlP0
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
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A proprietary approach developed by bringing together the best of learning theories from Psychology, design principles from the world of visualization, and pedagogical methods from over a decade of training experience, that enables you to: Learn better, faster!
1. NUCLEAR MEDICINE IMAGING IN
SPONDYLOARTHROPATHIES:
FROM SACROILIAC JOINT UPTAKE
RATIO TO HYBRID IMAGING
John T. Koutsikos, MD, PhD
Department of Nuclear Medicine
401 General Military Hospital,
Athens, Greece
2. INTRODUCTION
Spondylarthropathies (SpA) as a group have seronegative, inflammatory arthritis with
a relationship to HLA B27, characterized by involvement of the spine, peripheral
arthtitis and enthesitis.
Represent a variety of diagnoses, including ankylosing spondylitis (AS), reactive
arthritis, psoriasic arthritis (PsA), and enteropathic arthritis.
It is now more important than ever to diagnose and treat SpA early, since new
therapeutic agents have yielded tremendous responses not only in advanced disease
but also in the early stages of the disease.
3. IMAGING I
Imaging of the sacroiliac joints (SIJ) has an important role in the diagnosis, classification
and monitoring of patients with SpA.
Conventional radiography was given an outstanding role in the development of
classification New York (NY) criteria in 1961 and modified NY criteria in 1984.
However, radiographic sacroiliitis reflects structural changes which may appear late in
the disease process at least in a subset of patients. It has low specificity especially for
patients at the early stages of the disease.
To enable earlier diagnosis, highly reliable and sensitive imaging techniques are needed.
4.
5. IMAGING II
Magnetic resonance imaging (MRI) is used as a sensitive imaging modality for the
detection of sacroiliitis in early SpA.
MRI detects (early) inflammation such as bone marrow edema/osteitis, synovitis,
enthesitis and capsulitis associated with SpA
MRI has become a pivotal imaging tool for early diagnosis of axial SpA (recently
included as a major criterion in the ASAS classification criteria)
6.
7.
8.
9. SCINTIGRAPHY I
Four decades ago several reports about the diagnostic role of scintigraphy to detect
sacroiliitis were promising
10.
11.
12.
13. SCINTIGRAPHY II
Four decades ago several reports about the diagnostic role of scintigraphy to detect
sacroiliitis were promising
Bone scintigraphy was the method of choice and quantification of SIJ index has been
used as a diagnostic procedure to detect early sacroiliitis.
14.
15.
16. SCINTIGRAPHY III
Bone scintigraphy was the method of choice and quantification of SIJ index has been
used as a diagnostic procedure to detect early sacroiliitis.
However, data about the diagnostic value of bone scan to detect acute inflammatory
changes in the SIJ are conflicting and many studies suggest that scintigraphy of the SIJ is
at most of limited diagnostic value for the diagnosis of established SpA, including the
early diagnosis of probable/suspected sacroiliitis.
17.
18.
19. BONE SPECT
Single photon emission computed tomography (SPECT) of the bone, compared with planar
scintigraphy increases image contrast and improves lesion detection and localization.
Studies have documented the unique diagnostic information provided by SPECT in
patients with back pain.
In several studies bone SPECT appears to be an excellent diagnostic tool for active
sacroiliitis.
22. RADIOGRAPHIC SUSPICIOUS CHANGES IN THE SACROILIAC
JOINTS: THE ROLE OF BONE SINGLE PHOTON EMISSION
COMPUTED TOMOGRAPHY (SPECT) SCINTIGRAPHY
T. Pipikos1, J. Koutsikos1, S. Bakalis1, S. Episkopopoulou1, K.
Athanasiou1, G. Koniaris1, D. Kassimos2;
1 Nuclear Medicine dept., 2 Rheumatology dept.,
401 General Military Hospital, ATHENS, GREECE
23. AIM
To evaluate the role of bone single
photon emission computed tomography
(SPECT) scintigraphy in the detection of
sacroiliitis in patients with SpA and
suspicious changes of sacroiliitis on X-
ray.
X-ray, MRI, and SPECT of the sacroiliac
joints of 46 SpA patients (41 males, 5
females, mean age 28.2 y.o.) were
evaluated retrospectively.
Fourteen patients were classified as
grade 1
MRI detected features of sacroiliitis in
10/14 patients (71%)
24. SPECT FINDINGS
SPECT was (+)ve in all 10 MRI identified pts, as well as in one more male
with increased CRP and ECR.
In a 2-year follow up period, ankylosing spondylitis was established for this
patient.
28. SCINTIGRAPHY II
Other radiopharmaceuticals such as Ga-67, radiolabelled leucocytes, In-111 chloride,
99mTc labelled liposomes were demonstrated to accumulate in inflamed area in arthritis
However these agents have not been used in routine clinical practice.
99mTc labeled nonspecific polyclonal human immunoglobulin (HIG) accumulates in
infection and sterile inflammatory processes. HIG being a nonspecific marker of
inflammation and infection may help to detect active inflammation in SpA.