A presentation to high school students at Chula Vista High School, San Diego as part of nifty-fifty where scientists go into the high schools and try and excite students to a career in science. These slides describe my own particular career path.
What Can I Do With a Biology Degree? AIZKORRI ARANBURUbionaturehu
Conferencia impartida por Aizkorri Aranburu (Azti-Tecnalia), titulada "What Can I Do With a Biology Degree?" dentro de las Jornadas de orientación sobre las Salidas Profesionales en Biología, Bioquímica y CC Ambientales, organizadas por el Colegio Oficial de Biologos de Euskadi y BIONATUR (UPV/EHU).
What Can I Do With a Biology Degree? AIZKORRI ARANBURUbionaturehu
Conferencia impartida por Aizkorri Aranburu (Azti-Tecnalia), titulada "What Can I Do With a Biology Degree?" dentro de las Jornadas de orientación sobre las Salidas Profesionales en Biología, Bioquímica y CC Ambientales, organizadas por el Colegio Oficial de Biologos de Euskadi y BIONATUR (UPV/EHU).
Regional Student Group NBIC Career Presentation April 18, 2011Philip Bourne
Talk given to the Regional Student Group (RSG) of the Netherlands BioInformatics Center annual meeting on April 18, 2011. It is one scientists career path in bioinformatics.
Kim Solez The bridge between transplant and regenerative med Tissue engineeri...Kim Solez ,
Dr. Kim Solez presents "The Bridge Between Transplantation & Regenerative Medicine: The Beginning of Tissue Engineering Pathology" at the ATI Fellows Lecture Series on August 18, 2015.
Major organs in human body means vital organs which can not be live without for humans. also the comparison between vital and non-vital organs are important to know especially the ones about vital organs concepts in children. Children will be enthusiastic to know about their body and they will think and imagine in different ways.
Data collection methods to improve reproducibilityDigital Science
"Reproducibility, data collection, and laboratory management technologies" - Louis Culot, CEO of Biodata
Slides from Shaking It Up: Challenges and Solutions in Scholarly Information Management, San Francisco, April 22, 2015
Regional Student Group NBIC Career Presentation April 18, 2011Philip Bourne
Talk given to the Regional Student Group (RSG) of the Netherlands BioInformatics Center annual meeting on April 18, 2011. It is one scientists career path in bioinformatics.
Kim Solez The bridge between transplant and regenerative med Tissue engineeri...Kim Solez ,
Dr. Kim Solez presents "The Bridge Between Transplantation & Regenerative Medicine: The Beginning of Tissue Engineering Pathology" at the ATI Fellows Lecture Series on August 18, 2015.
Major organs in human body means vital organs which can not be live without for humans. also the comparison between vital and non-vital organs are important to know especially the ones about vital organs concepts in children. Children will be enthusiastic to know about their body and they will think and imagine in different ways.
Data collection methods to improve reproducibilityDigital Science
"Reproducibility, data collection, and laboratory management technologies" - Louis Culot, CEO of Biodata
Slides from Shaking It Up: Challenges and Solutions in Scholarly Information Management, San Francisco, April 22, 2015
Presented online as part of the NASM series in Advancing Drug Discovery see https://www.nationalacademies.org/event/40883_09-2023_advancing-drug-discovery-data-science-meets-drug-discovery
For a panel discussion at the Associate Research Libraries Spring meeting April 27, 2022, Montreal https://www.arl.org/schedule-for-spring-2022-association-meeting/
Frontiers of Computing at the Cellular and Molecular ScalesPhilip Bourne
3 basic points when establishing a new biomedical initiative. Presented at Frontiers of Computing in Health and Society, George Mason University, September 21, 2021.
Acetabularia Information For Class 9 .docxvaibhavrinwa19
Acetabularia acetabulum is a single-celled green alga that in its vegetative state is morphologically differentiated into a basal rhizoid and an axially elongated stalk, which bears whorls of branching hairs. The single diploid nucleus resides in the rhizoid.
Read| The latest issue of The Challenger is here! We are thrilled to announce that our school paper has qualified for the NATIONAL SCHOOLS PRESS CONFERENCE (NSPC) 2024. Thank you for your unwavering support and trust. Dive into the stories that made us stand out!
Embracing GenAI - A Strategic ImperativePeter Windle
Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
This Gasta posits a strategic approach to integrating AI into HEIs to prepare staff, students and the curriculum for an evolving world and workplace. We will highlight the advantages of working with these technologies beyond the realm of teaching, learning and assessment by considering prompt engineering skills, industry impact, curriculum changes, and the need for staff upskilling. In contrast, not engaging strategically with Generative AI poses risks, including falling behind peers, missed opportunities and failing to ensure our graduates remain employable. The rapid evolution of AI technologies necessitates a proactive and strategic approach if we are to remain relevant.
Introduction to AI for Nonprofits with Tapp NetworkTechSoup
Dive into the world of AI! Experts Jon Hill and Tareq Monaur will guide you through AI's role in enhancing nonprofit websites and basic marketing strategies, making it easy to understand and apply.
Instructions for Submissions thorugh G- Classroom.pptxJheel Barad
This presentation provides a briefing on how to upload submissions and documents in Google Classroom. It was prepared as part of an orientation for new Sainik School in-service teacher trainees. As a training officer, my goal is to ensure that you are comfortable and proficient with this essential tool for managing assignments and fostering student engagement.
Palestine last event orientationfvgnh .pptxRaedMohamed3
An EFL lesson about the current events in Palestine. It is intended to be for intermediate students who wish to increase their listening skills through a short lesson in power point.
How to Make a Field invisible in Odoo 17Celine George
It is possible to hide or invisible some fields in odoo. Commonly using “invisible” attribute in the field definition to invisible the fields. This slide will show how to make a field invisible in odoo 17.
Unit 8 - Information and Communication Technology (Paper I).pdfThiyagu K
This slides describes the basic concepts of ICT, basics of Email, Emerging Technology and Digital Initiatives in Education. This presentations aligns with the UGC Paper I syllabus.
Synthetic Fiber Construction in lab .pptxPavel ( NSTU)
Synthetic fiber production is a fascinating and complex field that blends chemistry, engineering, and environmental science. By understanding these aspects, students can gain a comprehensive view of synthetic fiber production, its impact on society and the environment, and the potential for future innovations. Synthetic fibers play a crucial role in modern society, impacting various aspects of daily life, industry, and the environment. ynthetic fibers are integral to modern life, offering a range of benefits from cost-effectiveness and versatility to innovative applications and performance characteristics. While they pose environmental challenges, ongoing research and development aim to create more sustainable and eco-friendly alternatives. Understanding the importance of synthetic fibers helps in appreciating their role in the economy, industry, and daily life, while also emphasizing the need for sustainable practices and innovation.
18. The Growth of Data is A Major Driver in Biology Number of released entries Year
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25. Need to Start with a 3D Drug-Receptor Complex - The PDB Contains Many Examples Computational Methodology Generic Name Other Name Treatment PDBid Lipitor Atorvastatin High cholesterol 1HWK, 1HW8… Testosterone Testosterone Osteoporosis 1AFS, 1I9J .. Taxol Paclitaxel Cancer 1JFF, 2HXF, 2HXH Viagra Sildenafil citrate ED, pulmonary arterial hypertension 1TBF, 1UDT, 1XOS.. Digoxin Lanoxin Congestive heart failure 1IGJ
26. A Reverse Engineering Approach to Drug Discovery Across Gene Families Characterize ligand binding site of primary target (Geometric Potential) Identify off-targets by ligand binding site similarity (Sequence order independent profile-profile alignment) Extract known drugs or inhibitors of the primary and/or off-targets Search for similar small molecules Dock molecules to both primary and off-targets Statistics analysis of docking score correlations … Xie and Bourne 2009 Bioinformatics 25(12) 305-312
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29. SMAP p-value < 1e-5 drugs TB proteins p < 1e-7 p < 1e-6 p < 1e-5
Tuberculosis, which is caused by the bacterial pathogen Mycobacterium tuberculosis , is a leading cause of mortality among the infectious diseases. It has been estimated by the World Health Organization (WHO) that almost one-third of the world's population , around 2 billion people, is infected with the disease. Every year, more than 8 million people develop an active form of the disease, which claims the lives of nearly 2 million. This translates to over 4,900 deaths per day , and more than 95% of these are in developing countries. Despite the current global situation, antitubercular drugs have remained largely unchanged over the last four decades. The widespread use of these agents has provided a strong selective pressure for M.tuberculosis, thus encouraging the emergence of resistant strains. Multidrug resistant (MDR) tuberculosis is defined as resistance to the first-line drugs isoniazid and rifampin . The effective treatment of MDR tuberculosis necessitates long-term use of second-line drug combinations , an unfortunate consequence of which is the emergence of further drug resistance. Enter extensively drug resistant (XDR) tuberculosis - M.tuberculosis strains that are resistant to both isoniazid plus rifampin, as well as key second-line drugs . Since the only remaining drug classes exhibit such low potency and high toxicity , XDR tuberculosis is extremely difficult to treat. The rise of XDR tuberculosis around the world imposes a great threat on human health , therefore reinforcing the development of new antitubercular agents as an urgent priority. Very few Mtb proteins explored as drug targets
Purple circular nodes are TB proteins and green rectangular nodes are drugs Binding site similarity is indicated by connecting lines (‘edges’) between the TB proteins and drugs - proteins that are predicted to have similar binding sites are connected Edges are colored according to SMAP p-value i.e. the significance of the match (green<=1e-5, blue<=1e-6, red<=1e-7) The thickness of the edges corresponds to the number binding sites of a particular drug that match the TB protein, expressed as a proportion of the total no. of different binding sites of that drug Dashed lines indicate that although all drug binding sites were matched, there was only one binding site for that drug anyway