This document summarizes drug trends in New York City in 2013. Key findings include heroin and opioid analgesics playing a large role in drug deaths, with opioids involved in 71% of overdose deaths. Heroin-related overdose deaths increased 84% from 2010 to 2012. Opioid analgesic prescriptions among NYC residents increased 30% from 2008 to 2012. Cocaine was the second most common drug identified in drug crime lab tests after marijuana.