The invention proposes a new approach to rare genetic diseases for which no cures are available, only symptomatic treatments through the preparation of novel multivalent molecules active toward the human enzymes responsible for them
The Significance of Lifescience- An In-depth Exploration.pdfhealthcare360social
Lifescience, an expansive and dynamic domain, unveils the enigmas of living organisms and their intricate connections with the environment. Its impact spans from molding pivotal medical advancements to influencing initiatives in conservation.
Haapalinna the new modalities ecosystem project what is there for meAntti Haapalinna
The document summarizes a presentation about the New Modalities Ecosystem Project between Orion Corporation and several academic and industry partners. The project aims to build competencies in developing new treatment modalities like biologics, peptides, gene therapies for rare diseases. It received public-private funding in August 2018. The ecosystem will increase understanding of disease pathways and enable development of novel drug targets, biomarkers, sensors, and digital tools to improve patient care and clinical research outcomes.
Association of Hygiene Hypothesis with High prevalence of Allergy and Autoimm...Agriculture Journal IJOEAR
Prevalence of Allergy and Autoimmune Diseases are high in developed countries, but not in developing countries. Helminth infection were associated with lower level of allergy but the mechanism is not yet clear. In hygiene countries like UK, Japan and Korea, Fecal Microbiota Transplantation (FMT) has gained interest as novel therapy and prevention and reach to medicine industrial manufactures. This study will support it by associate Hygiene Hypothesis (HyHy) and the high prevalence of Allergy and Autoimmune Disease. Systematic review and Bayesian network analysis in EBSCO host search engine were used. Result from dynaMed Evidence Based, Point-of-care Reference e Journals: Dentistry, Medical and Nursing has describe 9 literatures support the association of Hy-hy/parasite infection with Allergy and/ or Autoimmune Diseases: 2 publications of meta-analysis are chosen and supported by 5 cross sectional, longitudinal, cause-effect design, and 2 clinical and animal trial. Conclusions: Low-middle-high income countries has a life style of Hyhy pattern support FMT industrial medicine and travelling to developing countries with broad diversity bacteria and worm in therapeutic and prevention potential, supported by sub-saharan and tropical rainforest developing countries.
The Invention of the Mid-Infrared Generating Atomizer and its Human and Veter...semualkaira
In the current scenario, there
are different therapies for different diseases of human and animals. The existed therapies are associated with hurdles like drug
resistance, less sensitivity, side effects, uneconomical, etc. However, none of the therapies provide multi-disease management on
a molecular basis. Every disease originates due to inter and/or intra-molecular (cell/ tissue) changes, which changes their respective chemical bonds. Therapies focusing to rectify the molecular
changes (molecular medicine) are growing slowly, which could
act as a single remedy, but needs extensive multi-faculty research.
The Invention of the Mid-Infrared Generating Atomizer and its Human and Veter...semualkaira
In the current scenario, there
are different therapies for different diseases of human and animals. The existed therapies are associated with hurdles like drug
resistance, less sensitivity, side effects, uneconomical, etc. However, none of the therapies provide multi-disease management on
a molecular basis. Every disease originates due to inter and/or intra-molecular (cell/ tissue) changes, which changes their respective chemical bonds. Therapies focusing to rectify the molecular
changes (molecular medicine) are growing slowly, which could
act as a single remedy, but needs extensive multi-faculty research.
The Invention of the Mid-Infrared Generating Atomizer and its Human and Veter...semualkaira
In the current scenario, there
are different therapies for different diseases of human and animals. The existed therapies are associated with hurdles like drug
resistance, less sensitivity, side effects, uneconomical, etc. However, none of the therapies provide multi-disease management on
a molecular basis. Every disease originates due to inter and/or intra-molecular (cell/ tissue) changes, which changes their respective chemical bonds. Therapies focusing to rectify the molecular
changes (molecular medicine) are growing slowly, which could
act as a single remedy, but needs extensive multi-faculty research.
The Significance of Lifescience- An In-depth Exploration.pdfhealthcare360social
Lifescience, an expansive and dynamic domain, unveils the enigmas of living organisms and their intricate connections with the environment. Its impact spans from molding pivotal medical advancements to influencing initiatives in conservation.
Haapalinna the new modalities ecosystem project what is there for meAntti Haapalinna
The document summarizes a presentation about the New Modalities Ecosystem Project between Orion Corporation and several academic and industry partners. The project aims to build competencies in developing new treatment modalities like biologics, peptides, gene therapies for rare diseases. It received public-private funding in August 2018. The ecosystem will increase understanding of disease pathways and enable development of novel drug targets, biomarkers, sensors, and digital tools to improve patient care and clinical research outcomes.
Association of Hygiene Hypothesis with High prevalence of Allergy and Autoimm...Agriculture Journal IJOEAR
Prevalence of Allergy and Autoimmune Diseases are high in developed countries, but not in developing countries. Helminth infection were associated with lower level of allergy but the mechanism is not yet clear. In hygiene countries like UK, Japan and Korea, Fecal Microbiota Transplantation (FMT) has gained interest as novel therapy and prevention and reach to medicine industrial manufactures. This study will support it by associate Hygiene Hypothesis (HyHy) and the high prevalence of Allergy and Autoimmune Disease. Systematic review and Bayesian network analysis in EBSCO host search engine were used. Result from dynaMed Evidence Based, Point-of-care Reference e Journals: Dentistry, Medical and Nursing has describe 9 literatures support the association of Hy-hy/parasite infection with Allergy and/ or Autoimmune Diseases: 2 publications of meta-analysis are chosen and supported by 5 cross sectional, longitudinal, cause-effect design, and 2 clinical and animal trial. Conclusions: Low-middle-high income countries has a life style of Hyhy pattern support FMT industrial medicine and travelling to developing countries with broad diversity bacteria and worm in therapeutic and prevention potential, supported by sub-saharan and tropical rainforest developing countries.
The Invention of the Mid-Infrared Generating Atomizer and its Human and Veter...semualkaira
In the current scenario, there
are different therapies for different diseases of human and animals. The existed therapies are associated with hurdles like drug
resistance, less sensitivity, side effects, uneconomical, etc. However, none of the therapies provide multi-disease management on
a molecular basis. Every disease originates due to inter and/or intra-molecular (cell/ tissue) changes, which changes their respective chemical bonds. Therapies focusing to rectify the molecular
changes (molecular medicine) are growing slowly, which could
act as a single remedy, but needs extensive multi-faculty research.
The Invention of the Mid-Infrared Generating Atomizer and its Human and Veter...semualkaira
In the current scenario, there
are different therapies for different diseases of human and animals. The existed therapies are associated with hurdles like drug
resistance, less sensitivity, side effects, uneconomical, etc. However, none of the therapies provide multi-disease management on
a molecular basis. Every disease originates due to inter and/or intra-molecular (cell/ tissue) changes, which changes their respective chemical bonds. Therapies focusing to rectify the molecular
changes (molecular medicine) are growing slowly, which could
act as a single remedy, but needs extensive multi-faculty research.
The Invention of the Mid-Infrared Generating Atomizer and its Human and Veter...semualkaira
In the current scenario, there
are different therapies for different diseases of human and animals. The existed therapies are associated with hurdles like drug
resistance, less sensitivity, side effects, uneconomical, etc. However, none of the therapies provide multi-disease management on
a molecular basis. Every disease originates due to inter and/or intra-molecular (cell/ tissue) changes, which changes their respective chemical bonds. Therapies focusing to rectify the molecular
changes (molecular medicine) are growing slowly, which could
act as a single remedy, but needs extensive multi-faculty research.
Presentation on Pharmaceutical sectors In BangladeshMD Juboraj
10 South Colonnade, Canary Wharf, London, E14 4PU
Employees: 1,500
Annual budget: £100 million
Website: www.gov.uk/mhra
Parent organization: Department of Health and Social Care
Awards: None
Mission: To ensure medicines and medical devices work and are acceptably safe.
Jurisdiction: United Kingdom
Key people: Dr. June Raine, Chief Executive
Customer service: 020 3080 6000
Email: info@mhra.gov.uk
This document provides information on Withania coagulans and novel herbal drug delivery systems using nanotechnology. It discusses the botany, phytochemistry, and pharmacological properties of W. coagulans. The major constituents are withanolides. Extracts have shown anti-diabetic, anti-cancer, hepatoprotective, and antimicrobial effects. Nanotechnology can be used to develop herbal formulations for sustained drug release, improved bioavailability, and targeted drug delivery. Polymeric nanoparticles, liposomes, and nanoemulsions are some nanocarrier systems discussed. Further research on isolation of active compounds, toxicology, and transgenic techniques could help utilize the therapeutic potential of W. coagulans.
This document provides details about a study on the in vitro culture and transformation of Oldenlandia diffusa plants. The study investigated the effects of different cytokinin treatments on the morphogenesis and growth of O. diffusa explants in culture. It also examined the total phenolic content and antioxidant activity of extracts from the cultured plants. Finally, it describes a successful transformation of O. diffusa explants with Agrobacterium rhizogenes to produce hairy roots. Key findings include the observation that kinetin and basal salt content had little effect on shoot development, while BAP inhibited root growth. Extracts from plants grown with kinetin or BAP showed correlation between phenolic content and antioxidant activity. The transformation process resulted
This document summarizes the process undertaken by an ESCMID task force to develop European guidelines for the diagnosis and management of Candida diseases. The task force included members from various relevant medical societies. They created guidelines targeted towards four main patient populations at risk for Candida diseases. In addition to treatment recommendations, the guidelines provide guidance on diagnostic procedures. The guidelines were developed using the GRADE framework and were presented at ECCMID 2011 for discussion before finalization. The final guidelines aim to provide clinicians in Europe with guidance for diagnosing and managing Candida diseases.
Kits for modulation of anti-rejection therapies and early detection of neurod...Toscana Open Research
The patented technology is a nanofunctionalized device that enables the quantitative determination of the FKBP12 protein biomarker involved in many diseases. Quantification of FKBP12 in the blood allows for efficient monitoring of transplant patients and modulation of anti-rejection therapies, as well as early detection of neurodegenerative diseases. The device fills a gap by offering simple, sensitive quantification of FKBP12 directly in clinical settings. This supports proper dosing of immunosuppressive drugs for transplant patients and those with autoimmune diseases. It also enables early diagnosis of neurodegenerative conditions from easily obtained samples.
This document provides an overview of toxicology and its various branches. It defines key terms like toxicants, toxicity, acute toxicity, chronic toxicity, dose, etc. It describes the different types of toxicology like general toxicology, mechanistic toxicology, descriptive toxicology, and regulatory toxicology. For each type, it provides examples and explains their purpose and importance. It also discusses the importance of guidelines in regulatory toxicity studies for ensuring safety, efficacy and quality of medicines.
This document provides an overview of the various applications of chemistry in biological and medical sciences. It discusses how chemistry is applied in areas such as medicine and healthcare through drug development, food chemistry through food additives, structural biology through techniques like NMR and X-ray crystallography, nuclear chemistry in medical imaging and diagnosis, inorganic chemistry in metal-based drugs, and nanotechnology for targeted drug delivery and therapy. The document also gives examples of specific applications like anticancer drugs, preservatives, sweeteners, structural analysis of proteins, brain tumor detection using radiolabeling, and nanoparticle-based antimicrobial and anti-inflammatory treatments.
This document provides training materials for pharmaceutical students studying pathological physiology at Ivano-Frankivsk National Medical University in Ukraine. It includes a calendar of practical classes and lectures on topics like general pathology, nosology, inflammation, metabolism disorders and more. The document was prepared by three professors and approved by the university's medical commission. It aims to teach students key concepts and analyze typical pathological processes through 16 hours of classes and independent work.
This document provides an introduction to the field of pharmacology. It defines pharmacology and discusses the history and scope of the field. It describes different types of drugs sources including natural, semi-synthetic, synthetic and biosynthetic sources. It also outlines various routes of drug administration including local, oral, rectal, inhalation and parenteral routes. The document provides definitions of key terminologies and concepts in pharmacology including essential medicines.
Medicines and vaccines have helped deliver improvements in patient health. History shows us the great advances we have made - today we continue to see the potential to eradicate disease and improve health outcomes when we invest in science and adopt and use new medicines.
The Antimicrobial, Antioxidant and Antibacterial Effects of Seven Underexplor...IRJET Journal
This study evaluated the antimicrobial, antioxidant, and antibacterial properties of seven medicinal plant extracts. Phytochemical analysis revealed the presence of phenols, flavonoids, and steroids in all plant extracts. The extract of Psychotria peduncularis showed the highest total phenolic and flavonoid content. Antioxidant activity was determined using DPPH, hydroxyl, and nitric oxide radical scavenging assays. The extracts exhibited significant antioxidant effects. Antibacterial activity was evaluated against both bacteria and yeast, with the extracts of Tristemma Mauritianum and P. peduncularis showing the most potent effects. The results suggest that the screened plant extracts may be useful as sources for
This document is an academic thesis presented by Marcelo A. Dávila Cabrera at Lund University in Sweden. The thesis presents results from phytochemical studies of four Bolivian plants, including Senecio clivicolus, Prumnopitys exigua, Baccharis polycephala, and Podocarpus parlatorei. Various chromatographic and spectroscopic techniques were used to isolate and characterize secondary metabolites from the plants. The isolated compounds are described in four papers that are included in the thesis.
Introduction
Disease
Important Properties
Transmission & Epidemiology
Risk factor of reactivation
Pathogenesis
Clinical Findings
Laboratory Diagnosis
Approaches to the diagnosis of latent infections
Treatment
Prevention
Tesi Josep Rubert. CONTROL DE MICOTOXINES LC-MS(2)Josep Rubert
This document provides an introduction to mycotoxins. It discusses the history of mycotoxins, including outbreaks of ergotism in medieval Europe. It notes that mycotoxins are toxic secondary metabolites produced by filamentous fungi such as Aspergillus, Penicillium and Fusarium that can contaminate foods. While Claviceps was historically responsible for major mycotoxicosis, research interest increased in the 20th century with the discovery of aflatoxins. Mycotoxins are now considered an important food safety issue globally due to their risks to human and animal health as well as economic losses. The document stresses the need for intensified monitoring and controls of my
This curriculum vitae summarizes the career and qualifications of Paul Lorenz Bigliardi. He is a Swiss citizen and Singapore permanent resident who has over 30 years of experience in dermatology and allergology. He currently holds several senior positions including director of the Clinical Research Unit for Skin, Allergy and Regeneration in Singapore. His research focuses on areas such as wound healing, skin toxicology, neurodermatology, and photobiology. He has over 50 peer-reviewed publications and has received several awards and research grants over his career.
Epidemiology of Poisoning and Perception towards Poison Management Guidelin...iosrphr_editor
The IOSR Journal of Pharmacy (IOSRPHR) is an open access online & offline peer reviewed international journal, which publishes innovative research papers, reviews, mini-reviews, short communications and notes dealing with Pharmaceutical Sciences( Pharmaceutical Technology, Pharmaceutics, Biopharmaceutics, Pharmacokinetics, Pharmaceutical/Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmacognosy & Phytochemistry, Pharmacology, Pharmaceutical Analysis, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics and Biotechnology of Pharmaceutical Interest........more details on Aim & Scope).
The document discusses several applications of genomics and bioinformatics across various fields such as medicine, agriculture, microbiology, and more. It describes how genomic studies of humans and model organisms are providing insights into disease mechanisms and treatments. Applications in agriculture include developing crops with improved traits like insect or drought resistance. Microbial genomics is explored for uses like bioremediation, alternative energy, and industrial applications. Bioinformatics tools aid research through literature retrieval and comparative genomics studies.
Conference italy vietnam for food quality and safety 18 novatbimau
The document outlines the schedule and program for a conference on food quality and safety co-hosted by Italy and Vietnam. The conference includes an opening session with remarks from government officials, followed by panels on policies and the EU-Vietnam Free Trade Agreement. Presentations will cover topics like Italian food technology, food traceability using stable isotopes and DNA analysis. A scientific symposium in the afternoon involves two sessions on food quality/traceability and green production/processing, with panelists from Italy and Vietnam universities and research institutes.
Nanoparticles in lung cancer treatment and diagnosis.mohamedAhmed1628
1. The document discusses recent advances in using nanoparticles for the diagnosis and treatment of lung cancer.
2. It outlines different types of nanoparticles like liposomes, polymer nanoparticles, dendrimers, gold nanoparticles, and silica nanoparticles that have been used to target lung cancer cells and enhance drug delivery.
3. Recent applications show these nanoparticles can help increase drug concentrations in tumors, induce cancer cell apoptosis, and selectively target cancer cells while reducing side effects - showing promise for improved lung cancer treatment.
Sirit: the fascist internment system in Tuscany during World War II (1940-44)...Toscana Open Research
The research project focused on the Fascist internment system in Tuscany between 1940, when Italy joined the Second World War, and 1944, when the region was liberated by the Allied Army. During the war, the Fascist government and the Italian Social Republic adopted a series of measures restricting individual freedom. This led to the isolation, imprisonment, marginalization and control of anyone deemed dangerous for public security, even only on the basis of mere suspicion. These provisions resulted in a widespread and articulated network of internment devices that affected different categories of persons.
Sirit: Il sistema di internamento e di reclusione in Toscana (1940-1944): dal...Toscana Open Research
Il progetto di ricerca SIRIT prende in esame il sistema di internamento fascista in Toscana tra l’ingresso dell’Italia nella Seconda guerra mondiale (1940) e la liberazione della regione (1944). Durante la guerra, il governo fascista e la Repubblica Sociale Italiana adottarono una serie di misure restrittive della libertà individuale che portarono all’isolamento, alla reclusione, alla marginalizzazione e al controllo di chiunque fosse ritenuto pericoloso per l’ordine pubblico. Oggetto di ricerca di SIRIT sono proprio queste misure che si tradussero in una fitta rete di dispositivi e provvedimenti di internamento, che colpirono diverse categorie di persone
Presentation on Pharmaceutical sectors In BangladeshMD Juboraj
10 South Colonnade, Canary Wharf, London, E14 4PU
Employees: 1,500
Annual budget: £100 million
Website: www.gov.uk/mhra
Parent organization: Department of Health and Social Care
Awards: None
Mission: To ensure medicines and medical devices work and are acceptably safe.
Jurisdiction: United Kingdom
Key people: Dr. June Raine, Chief Executive
Customer service: 020 3080 6000
Email: info@mhra.gov.uk
This document provides information on Withania coagulans and novel herbal drug delivery systems using nanotechnology. It discusses the botany, phytochemistry, and pharmacological properties of W. coagulans. The major constituents are withanolides. Extracts have shown anti-diabetic, anti-cancer, hepatoprotective, and antimicrobial effects. Nanotechnology can be used to develop herbal formulations for sustained drug release, improved bioavailability, and targeted drug delivery. Polymeric nanoparticles, liposomes, and nanoemulsions are some nanocarrier systems discussed. Further research on isolation of active compounds, toxicology, and transgenic techniques could help utilize the therapeutic potential of W. coagulans.
This document provides details about a study on the in vitro culture and transformation of Oldenlandia diffusa plants. The study investigated the effects of different cytokinin treatments on the morphogenesis and growth of O. diffusa explants in culture. It also examined the total phenolic content and antioxidant activity of extracts from the cultured plants. Finally, it describes a successful transformation of O. diffusa explants with Agrobacterium rhizogenes to produce hairy roots. Key findings include the observation that kinetin and basal salt content had little effect on shoot development, while BAP inhibited root growth. Extracts from plants grown with kinetin or BAP showed correlation between phenolic content and antioxidant activity. The transformation process resulted
This document summarizes the process undertaken by an ESCMID task force to develop European guidelines for the diagnosis and management of Candida diseases. The task force included members from various relevant medical societies. They created guidelines targeted towards four main patient populations at risk for Candida diseases. In addition to treatment recommendations, the guidelines provide guidance on diagnostic procedures. The guidelines were developed using the GRADE framework and were presented at ECCMID 2011 for discussion before finalization. The final guidelines aim to provide clinicians in Europe with guidance for diagnosing and managing Candida diseases.
Kits for modulation of anti-rejection therapies and early detection of neurod...Toscana Open Research
The patented technology is a nanofunctionalized device that enables the quantitative determination of the FKBP12 protein biomarker involved in many diseases. Quantification of FKBP12 in the blood allows for efficient monitoring of transplant patients and modulation of anti-rejection therapies, as well as early detection of neurodegenerative diseases. The device fills a gap by offering simple, sensitive quantification of FKBP12 directly in clinical settings. This supports proper dosing of immunosuppressive drugs for transplant patients and those with autoimmune diseases. It also enables early diagnosis of neurodegenerative conditions from easily obtained samples.
This document provides an overview of toxicology and its various branches. It defines key terms like toxicants, toxicity, acute toxicity, chronic toxicity, dose, etc. It describes the different types of toxicology like general toxicology, mechanistic toxicology, descriptive toxicology, and regulatory toxicology. For each type, it provides examples and explains their purpose and importance. It also discusses the importance of guidelines in regulatory toxicity studies for ensuring safety, efficacy and quality of medicines.
This document provides an overview of the various applications of chemistry in biological and medical sciences. It discusses how chemistry is applied in areas such as medicine and healthcare through drug development, food chemistry through food additives, structural biology through techniques like NMR and X-ray crystallography, nuclear chemistry in medical imaging and diagnosis, inorganic chemistry in metal-based drugs, and nanotechnology for targeted drug delivery and therapy. The document also gives examples of specific applications like anticancer drugs, preservatives, sweeteners, structural analysis of proteins, brain tumor detection using radiolabeling, and nanoparticle-based antimicrobial and anti-inflammatory treatments.
This document provides training materials for pharmaceutical students studying pathological physiology at Ivano-Frankivsk National Medical University in Ukraine. It includes a calendar of practical classes and lectures on topics like general pathology, nosology, inflammation, metabolism disorders and more. The document was prepared by three professors and approved by the university's medical commission. It aims to teach students key concepts and analyze typical pathological processes through 16 hours of classes and independent work.
This document provides an introduction to the field of pharmacology. It defines pharmacology and discusses the history and scope of the field. It describes different types of drugs sources including natural, semi-synthetic, synthetic and biosynthetic sources. It also outlines various routes of drug administration including local, oral, rectal, inhalation and parenteral routes. The document provides definitions of key terminologies and concepts in pharmacology including essential medicines.
Medicines and vaccines have helped deliver improvements in patient health. History shows us the great advances we have made - today we continue to see the potential to eradicate disease and improve health outcomes when we invest in science and adopt and use new medicines.
The Antimicrobial, Antioxidant and Antibacterial Effects of Seven Underexplor...IRJET Journal
This study evaluated the antimicrobial, antioxidant, and antibacterial properties of seven medicinal plant extracts. Phytochemical analysis revealed the presence of phenols, flavonoids, and steroids in all plant extracts. The extract of Psychotria peduncularis showed the highest total phenolic and flavonoid content. Antioxidant activity was determined using DPPH, hydroxyl, and nitric oxide radical scavenging assays. The extracts exhibited significant antioxidant effects. Antibacterial activity was evaluated against both bacteria and yeast, with the extracts of Tristemma Mauritianum and P. peduncularis showing the most potent effects. The results suggest that the screened plant extracts may be useful as sources for
This document is an academic thesis presented by Marcelo A. Dávila Cabrera at Lund University in Sweden. The thesis presents results from phytochemical studies of four Bolivian plants, including Senecio clivicolus, Prumnopitys exigua, Baccharis polycephala, and Podocarpus parlatorei. Various chromatographic and spectroscopic techniques were used to isolate and characterize secondary metabolites from the plants. The isolated compounds are described in four papers that are included in the thesis.
Introduction
Disease
Important Properties
Transmission & Epidemiology
Risk factor of reactivation
Pathogenesis
Clinical Findings
Laboratory Diagnosis
Approaches to the diagnosis of latent infections
Treatment
Prevention
Tesi Josep Rubert. CONTROL DE MICOTOXINES LC-MS(2)Josep Rubert
This document provides an introduction to mycotoxins. It discusses the history of mycotoxins, including outbreaks of ergotism in medieval Europe. It notes that mycotoxins are toxic secondary metabolites produced by filamentous fungi such as Aspergillus, Penicillium and Fusarium that can contaminate foods. While Claviceps was historically responsible for major mycotoxicosis, research interest increased in the 20th century with the discovery of aflatoxins. Mycotoxins are now considered an important food safety issue globally due to their risks to human and animal health as well as economic losses. The document stresses the need for intensified monitoring and controls of my
This curriculum vitae summarizes the career and qualifications of Paul Lorenz Bigliardi. He is a Swiss citizen and Singapore permanent resident who has over 30 years of experience in dermatology and allergology. He currently holds several senior positions including director of the Clinical Research Unit for Skin, Allergy and Regeneration in Singapore. His research focuses on areas such as wound healing, skin toxicology, neurodermatology, and photobiology. He has over 50 peer-reviewed publications and has received several awards and research grants over his career.
Epidemiology of Poisoning and Perception towards Poison Management Guidelin...iosrphr_editor
The IOSR Journal of Pharmacy (IOSRPHR) is an open access online & offline peer reviewed international journal, which publishes innovative research papers, reviews, mini-reviews, short communications and notes dealing with Pharmaceutical Sciences( Pharmaceutical Technology, Pharmaceutics, Biopharmaceutics, Pharmacokinetics, Pharmaceutical/Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmacognosy & Phytochemistry, Pharmacology, Pharmaceutical Analysis, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics and Biotechnology of Pharmaceutical Interest........more details on Aim & Scope).
The document discusses several applications of genomics and bioinformatics across various fields such as medicine, agriculture, microbiology, and more. It describes how genomic studies of humans and model organisms are providing insights into disease mechanisms and treatments. Applications in agriculture include developing crops with improved traits like insect or drought resistance. Microbial genomics is explored for uses like bioremediation, alternative energy, and industrial applications. Bioinformatics tools aid research through literature retrieval and comparative genomics studies.
Conference italy vietnam for food quality and safety 18 novatbimau
The document outlines the schedule and program for a conference on food quality and safety co-hosted by Italy and Vietnam. The conference includes an opening session with remarks from government officials, followed by panels on policies and the EU-Vietnam Free Trade Agreement. Presentations will cover topics like Italian food technology, food traceability using stable isotopes and DNA analysis. A scientific symposium in the afternoon involves two sessions on food quality/traceability and green production/processing, with panelists from Italy and Vietnam universities and research institutes.
Nanoparticles in lung cancer treatment and diagnosis.mohamedAhmed1628
1. The document discusses recent advances in using nanoparticles for the diagnosis and treatment of lung cancer.
2. It outlines different types of nanoparticles like liposomes, polymer nanoparticles, dendrimers, gold nanoparticles, and silica nanoparticles that have been used to target lung cancer cells and enhance drug delivery.
3. Recent applications show these nanoparticles can help increase drug concentrations in tumors, induce cancer cell apoptosis, and selectively target cancer cells while reducing side effects - showing promise for improved lung cancer treatment.
Sirit: the fascist internment system in Tuscany during World War II (1940-44)...Toscana Open Research
The research project focused on the Fascist internment system in Tuscany between 1940, when Italy joined the Second World War, and 1944, when the region was liberated by the Allied Army. During the war, the Fascist government and the Italian Social Republic adopted a series of measures restricting individual freedom. This led to the isolation, imprisonment, marginalization and control of anyone deemed dangerous for public security, even only on the basis of mere suspicion. These provisions resulted in a widespread and articulated network of internment devices that affected different categories of persons.
Sirit: Il sistema di internamento e di reclusione in Toscana (1940-1944): dal...Toscana Open Research
Il progetto di ricerca SIRIT prende in esame il sistema di internamento fascista in Toscana tra l’ingresso dell’Italia nella Seconda guerra mondiale (1940) e la liberazione della regione (1944). Durante la guerra, il governo fascista e la Repubblica Sociale Italiana adottarono una serie di misure restrittive della libertà individuale che portarono all’isolamento, alla reclusione, alla marginalizzazione e al controllo di chiunque fosse ritenuto pericoloso per l’ordine pubblico. Oggetto di ricerca di SIRIT sono proprio queste misure che si tradussero in una fitta rete di dispositivi e provvedimenti di internamento, che colpirono diverse categorie di persone
BIO-SCULT ha condotto un censimento di tutte le opere conservate nelle sale e nei depositi di Villa Corsini, verificando e - in moltissimi casi - recuperando i numeri di inventario delle sculture, andati perduti in seguito ai danni arrecati al Museo dall’alluvione e al trasferimento a Villa Corsini della sua collezione di marmi. Si è creato un database che è diventato la base per un catalogo tridimensionale delle sculture che, grazie a ricostruzioni 3D, consente a tutti la fruizione dell'intera collezione
Il progetto ha permesso la fruizione di testi, metadati, immagini, video ed esecuzioni musicali nei luoghi turistici dell’area senese tramite lo sviluppo della Realtà Aumentata.
The MeB project, resulted from the collaboration between the Scuola Normale Superiore and the Bargello Museums. Its main objective was the development of shared, applied research, aimed at the modernization of the scientific analysis processes and art-historical study of small-scale metal production of the Early Modern age. Moreover, it aimed at elaborating new operational solutions of potential interest for similar cultural contexts, also throughout the use of 3D laser scans.
Il progetto MeB, frutto della collaborazione tra la Scuola Normale Superiore e i Musei del Bargello, ha avuto come principale obiettivo quello di sviluppare una ricerca condivisa di natura applicativa, finalizzata alla modernizzazione dei processi di analisi scientifica e studio storico-artistico della produzione metallica di piccole dimensioni d’età moderna e all’elaborazione, anche attraverso scansioni laser 3D, di soluzioni operative di potenziale interesse per analoghi contesti culturali.
L’unità di Ricerca applica due strategie di design. La prima - principale - attiene alla possibilità di garantire ad ogni persona l’utilizzo di luoghi, beni e servizi, secondo i principi dello Universal Design; la seconda - in sinergia con la prima - attiene alla predisposizione di specifici dispositivi di sostegno e di specifiche tecnologie (Assistive Technologies/Adaptive Technologies) volti a consentire a persone con particolari esigenze di tipo fisico, senso-percettivo o cognitivo una migliore qualità della vita.
Riconoscimento di minerali in luce trasmessa e riflessa o diffrazione X, studi paragenetici, determinazione di elementi maggiori e in tracce,
tecniche di microanalisi, studi di speciazione mediante tecniche di estrazione sequenziali, misurazioni di concentrazioni di Hg a livello di ultratracce
L’attività di ricerca sul tema dei beni culturali 4 0 (BBCC 4 0 si svolge su più fronti una parte si concentra sulle analisi diagnostiche dei Beni Culturali ed un’altra sul trasferimento tecnologico delle competenze e delle conoscenze. Parte della ricerca sul tema include il riutilizzo del materiale di scarto della filiera dell’estrazione e lavorazione del marmo di Carrara, ovvero polveri e sabbie di carbonato di calcio
Designing and monitoring new learning models;
creating solutions for improving the well-being of employees;
psychometric and neurometric analyses for creating either inbound or outbound effectivecommunication strategies;
psychometric analyses of personality traits, leadership, and social interactions oncompany personnel aimed at creating predictive models of the success in relocatingresources;
human resources management.
Knowledge and tools aimed at characterizing sleep in physiological and
pathological conditions. Develops and tests approaches and tools aimed at intervening on sleep to modify its efficiency and functions.
Normative and descriptive models of reasoning, Analysis of experts’ judgment and decision-making, monitoring, counseling, and correction of toxic behaviors on social media (fake news, misinformation, conspiracy theories, etc.)
Managerial and organizational neurosciences to increase company valuesToscana Open Research
The research activity presides the application
of managerial and organizational neurosciences, psychophysiology and advanced analytical
approaches, offering possible services and applications in four business domains: Training,
Cognitive Ergonomics, Communication, Resources human
Process for obtaining levulinic acid esters, in particular alkyl levulinatesToscana Open Research
Our patented process is useful to obtain levulinic acid esters by direct alcoholysis of carbohydrates, such as C6 monosaccharides and/or polysaccharides thereof and/or chitin and/or chitosan, with a predetermined alcohol, takes place at a reaction temperature preferably between 100°C and 220°C for a time preferably between 30 and 300 minutes and in the presence of a co-solvent with specific properties, in addition to a conventional acid catalyst said alcohol and said co
solvent are preferably separated from the reaction mixture after conversion and then, recycled back to the conversion step
Procedimento per ottenere esteri dell'acido levulinico, in particolare alchil...Toscana Open Research
Il nostro processo brevettato è utile ad ottenere esteri dell’acido levulinico mediante alcolisi diretta di carboidrati, come monosaccaridi C6 e/o loro polisaccaridi e/o chitina e/o chitosano con un alcol predeterminato, ha luogo a una
temperatura di reazione preferibilmente compresa tra 100 C e 220 C per un tempo
preferibilmente compreso tra 30 e 300 minuti e in presenza, oltre che di un catalizzatore acido di tipo convenzionale, di un co solvente avente specifiche caratteristiche il suddetto alcol e detto solvente saranno preferibilmente separati
dalla miscela di reazione dopo conversione e riciclati alla fase di conversione
Materiale e sistema per il trattamento terapeutico di articolazioniToscana Open Research
L’invenzione vuole sostituire il bisogno di iniezioni ripetute per la rigenerazione dei tessuti e/o gli interventi chirurgici per la sostituzione dell’intera giunzione articolare. Si tratta di un materiale composito a base organica rilasciato da una stampante 3D integrata in un tool artroscopico.
This document describes a material and treatment system for regenerating cartilage tissue in joints. The system utilizes a 3D printed composite material that is implanted using minimally invasive surgery and stimulates tissue regeneration in situ using ultrasound, without multiple interventions. The material and system could enable treatment of osteoarthritis and other degenerative diseases through stem cell-mediated regenerative techniques. The inventors are exploring partnerships with industrial companies interested in licensing the technology.
Manoscritti e testi filosofici tra Oriente e Occidente dal Medioevo ai giorni...Toscana Open Research
Il focus di ricerca sulle zone liminari della storia della filosofia, ai confini tra civiltà diverse e spesso ritenute inevitabilmente conflittuali, permette a PhiBor di costituire un vero e proprio laboratorio vivente di interculturalità, intesa sia come interscambio tra differenti civiltà, sia come interfaccia razionale tra modelli conoscitivi distinti
The extracorporeal clearance precision measurement system allows clearance rate of extracorporeal treatments to be measured in real time and adjusted to patients’ needs.
Discovery of An Apparent Red, High-Velocity Type Ia Supernova at 𝐳 = 2.9 wi...Sérgio Sacani
We present the JWST discovery of SN 2023adsy, a transient object located in a host galaxy JADES-GS
+
53.13485
−
27.82088
with a host spectroscopic redshift of
2.903
±
0.007
. The transient was identified in deep James Webb Space Telescope (JWST)/NIRCam imaging from the JWST Advanced Deep Extragalactic Survey (JADES) program. Photometric and spectroscopic followup with NIRCam and NIRSpec, respectively, confirm the redshift and yield UV-NIR light-curve, NIR color, and spectroscopic information all consistent with a Type Ia classification. Despite its classification as a likely SN Ia, SN 2023adsy is both fairly red (
�
(
�
−
�
)
∼
0.9
) despite a host galaxy with low-extinction and has a high Ca II velocity (
19
,
000
±
2
,
000
km/s) compared to the general population of SNe Ia. While these characteristics are consistent with some Ca-rich SNe Ia, particularly SN 2016hnk, SN 2023adsy is intrinsically brighter than the low-
�
Ca-rich population. Although such an object is too red for any low-
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cosmological sample, we apply a fiducial standardization approach to SN 2023adsy and find that the SN 2023adsy luminosity distance measurement is in excellent agreement (
≲
1
�
) with
Λ
CDM. Therefore unlike low-
�
Ca-rich SNe Ia, SN 2023adsy is standardizable and gives no indication that SN Ia standardized luminosities change significantly with redshift. A larger sample of distant SNe Ia is required to determine if SN Ia population characteristics at high-
�
truly diverge from their low-
�
counterparts, and to confirm that standardized luminosities nevertheless remain constant with redshift.
(June 12, 2024) Webinar: Development of PET theranostics targeting the molecu...Scintica Instrumentation
Targeting Hsp90 and its pathogen Orthologs with Tethered Inhibitors as a Diagnostic and Therapeutic Strategy for cancer and infectious diseases with Dr. Timothy Haystead.
Candidate young stellar objects in the S-cluster: Kinematic analysis of a sub...Sérgio Sacani
Context. The observation of several L-band emission sources in the S cluster has led to a rich discussion of their nature. However, a definitive answer to the classification of the dusty objects requires an explanation for the detection of compact Doppler-shifted Brγ emission. The ionized hydrogen in combination with the observation of mid-infrared L-band continuum emission suggests that most of these sources are embedded in a dusty envelope. These embedded sources are part of the S-cluster, and their relationship to the S-stars is still under debate. To date, the question of the origin of these two populations has been vague, although all explanations favor migration processes for the individual cluster members. Aims. This work revisits the S-cluster and its dusty members orbiting the supermassive black hole SgrA* on bound Keplerian orbits from a kinematic perspective. The aim is to explore the Keplerian parameters for patterns that might imply a nonrandom distribution of the sample. Additionally, various analytical aspects are considered to address the nature of the dusty sources. Methods. Based on the photometric analysis, we estimated the individual H−K and K−L colors for the source sample and compared the results to known cluster members. The classification revealed a noticeable contrast between the S-stars and the dusty sources. To fit the flux-density distribution, we utilized the radiative transfer code HYPERION and implemented a young stellar object Class I model. We obtained the position angle from the Keplerian fit results; additionally, we analyzed the distribution of the inclinations and the longitudes of the ascending node. Results. The colors of the dusty sources suggest a stellar nature consistent with the spectral energy distribution in the near and midinfrared domains. Furthermore, the evaporation timescales of dusty and gaseous clumps in the vicinity of SgrA* are much shorter ( 2yr) than the epochs covered by the observations (≈15yr). In addition to the strong evidence for the stellar classification of the D-sources, we also find a clear disk-like pattern following the arrangements of S-stars proposed in the literature. Furthermore, we find a global intrinsic inclination for all dusty sources of 60 ± 20◦, implying a common formation process. Conclusions. The pattern of the dusty sources manifested in the distribution of the position angles, inclinations, and longitudes of the ascending node strongly suggests two different scenarios: the main-sequence stars and the dusty stellar S-cluster sources share a common formation history or migrated with a similar formation channel in the vicinity of SgrA*. Alternatively, the gravitational influence of SgrA* in combination with a massive perturber, such as a putative intermediate mass black hole in the IRS 13 cluster, forces the dusty objects and S-stars to follow a particular orbital arrangement. Key words. stars: black holes– stars: formation– Galaxy: center– galaxies: star formation
Describing and Interpreting an Immersive Learning Case with the Immersion Cub...Leonel Morgado
Current descriptions of immersive learning cases are often difficult or impossible to compare. This is due to a myriad of different options on what details to include, which aspects are relevant, and on the descriptive approaches employed. Also, these aspects often combine very specific details with more general guidelines or indicate intents and rationales without clarifying their implementation. In this paper we provide a method to describe immersive learning cases that is structured to enable comparisons, yet flexible enough to allow researchers and practitioners to decide which aspects to include. This method leverages a taxonomy that classifies educational aspects at three levels (uses, practices, and strategies) and then utilizes two frameworks, the Immersive Learning Brain and the Immersion Cube, to enable a structured description and interpretation of immersive learning cases. The method is then demonstrated on a published immersive learning case on training for wind turbine maintenance using virtual reality. Applying the method results in a structured artifact, the Immersive Learning Case Sheet, that tags the case with its proximal uses, practices, and strategies, and refines the free text case description to ensure that matching details are included. This contribution is thus a case description method in support of future comparative research of immersive learning cases. We then discuss how the resulting description and interpretation can be leveraged to change immersion learning cases, by enriching them (considering low-effort changes or additions) or innovating (exploring more challenging avenues of transformation). The method holds significant promise to support better-grounded research in immersive learning.
SDSS1335+0728: The awakening of a ∼ 106M⊙ black hole⋆Sérgio Sacani
Context. The early-type galaxy SDSS J133519.91+072807.4 (hereafter SDSS1335+0728), which had exhibited no prior optical variations during the preceding two decades, began showing significant nuclear variability in the Zwicky Transient Facility (ZTF) alert stream from December 2019 (as ZTF19acnskyy). This variability behaviour, coupled with the host-galaxy properties, suggests that SDSS1335+0728 hosts a ∼ 106M⊙ black hole (BH) that is currently in the process of ‘turning on’. Aims. We present a multi-wavelength photometric analysis and spectroscopic follow-up performed with the aim of better understanding the origin of the nuclear variations detected in SDSS1335+0728. Methods. We used archival photometry (from WISE, 2MASS, SDSS, GALEX, eROSITA) and spectroscopic data (from SDSS and LAMOST) to study the state of SDSS1335+0728 prior to December 2019, and new observations from Swift, SOAR/Goodman, VLT/X-shooter, and Keck/LRIS taken after its turn-on to characterise its current state. We analysed the variability of SDSS1335+0728 in the X-ray/UV/optical/mid-infrared range, modelled its spectral energy distribution prior to and after December 2019, and studied the evolution of its UV/optical spectra. Results. From our multi-wavelength photometric analysis, we find that: (a) since 2021, the UV flux (from Swift/UVOT observations) is four times brighter than the flux reported by GALEX in 2004; (b) since June 2022, the mid-infrared flux has risen more than two times, and the W1−W2 WISE colour has become redder; and (c) since February 2024, the source has begun showing X-ray emission. From our spectroscopic follow-up, we see that (i) the narrow emission line ratios are now consistent with a more energetic ionising continuum; (ii) broad emission lines are not detected; and (iii) the [OIII] line increased its flux ∼ 3.6 years after the first ZTF alert, which implies a relatively compact narrow-line-emitting region. Conclusions. We conclude that the variations observed in SDSS1335+0728 could be either explained by a ∼ 106M⊙ AGN that is just turning on or by an exotic tidal disruption event (TDE). If the former is true, SDSS1335+0728 is one of the strongest cases of an AGNobserved in the process of activating. If the latter were found to be the case, it would correspond to the longest and faintest TDE ever observed (or another class of still unknown nuclear transient). Future observations of SDSS1335+0728 are crucial to further understand its behaviour. Key words. galaxies: active– accretion, accretion discs– galaxies: individual: SDSS J133519.91+072807.4
CLASS 12th CHEMISTRY SOLID STATE ppt (Animated)eitps1506
Description:
Dive into the fascinating realm of solid-state physics with our meticulously crafted online PowerPoint presentation. This immersive educational resource offers a comprehensive exploration of the fundamental concepts, theories, and applications within the realm of solid-state physics.
From crystalline structures to semiconductor devices, this presentation delves into the intricate principles governing the behavior of solids, providing clear explanations and illustrative examples to enhance understanding. Whether you're a student delving into the subject for the first time or a seasoned researcher seeking to deepen your knowledge, our presentation offers valuable insights and in-depth analyses to cater to various levels of expertise.
Key topics covered include:
Crystal Structures: Unravel the mysteries of crystalline arrangements and their significance in determining material properties.
Band Theory: Explore the electronic band structure of solids and understand how it influences their conductive properties.
Semiconductor Physics: Delve into the behavior of semiconductors, including doping, carrier transport, and device applications.
Magnetic Properties: Investigate the magnetic behavior of solids, including ferromagnetism, antiferromagnetism, and ferrimagnetism.
Optical Properties: Examine the interaction of light with solids, including absorption, reflection, and transmission phenomena.
With visually engaging slides, informative content, and interactive elements, our online PowerPoint presentation serves as a valuable resource for students, educators, and enthusiasts alike, facilitating a deeper understanding of the captivating world of solid-state physics. Explore the intricacies of solid-state materials and unlock the secrets behind their remarkable properties with our comprehensive presentation.
TOPIC OF DISCUSSION: CENTRIFUGATION SLIDESHARE.pptxshubhijain836
Centrifugation is a powerful technique used in laboratories to separate components of a heterogeneous mixture based on their density. This process utilizes centrifugal force to rapidly spin samples, causing denser particles to migrate outward more quickly than lighter ones. As a result, distinct layers form within the sample tube, allowing for easy isolation and purification of target substances.
PPT on Direct Seeded Rice presented at the three-day 'Training and Validation Workshop on Modules of Climate Smart Agriculture (CSA) Technologies in South Asia' workshop on April 22, 2024.
PPT on Sustainable Land Management presented at the three-day 'Training and Validation Workshop on Modules of Climate Smart Agriculture (CSA) Technologies in South Asia' workshop on April 22, 2024.
Sustainable Land Management - Climate Smart Agriculture
New Dendrimeric Pyrrolidines
1. New Dendrimeric
Pyrrolidines
INVENTORS: Francesca Cardona
Serena Catarzi
Giampiero D’Adamio
Andrea Goti
Camilla Matassini
Amelia Morrone
Camilla Parmeggiani
CONTITOLARI: Meyer – Azienda Ospedaliero Universitaria
STATUS PATENT: Granteed
N° Priority: 102016000013155
DATE: 1 agosto 2018
Patent family: WO2017137895A1
2. The invention proposes a new approach to rare genetic diseases for which no cures are available, only symptomatic
treatments through the preparation of novel multivalent molecules active toward the human enzymes responsible
for them. Lysosomal storage diseases (LSDs) are a group of rare metabolic diseases caused by deficits in lysosomal
enzymes to date orphaned by treatments.
The invention is aimed at developing an effective, noninvasive therapy for the treatment of two metabolic diseases,
Mucopolysaccharidosis IV (also known as Morquio A) and Mucopolysaccharidosis II (also known as Hunter's disease).
Lysosomal storage diseases, a group of inherited metabolic disorders, are rare when taken individually, but are
substantially numerous when taken as a whole since about one in 5000-8000 infants is affected. These diseases are
"orphaned" by treatments that provide a definitive cure, but are treated only symptomatically. Our molecules are
proposed as pharmacological chaperones (PCs), molecules capable of restoring deficient enzyme activity, or as
stabilizers for the current marketed treatment, enzyme replacement therapy (ERT), which has various problems
including poor stability of the exogenous enzyme.
The invention
4. The Inventors
Francesca Cardona, associate professor at the
University of Florence since 2015. PhD in
Chemical Sciences in 1998. Received the "G.
Ciamician" Medal from the Italian Chemical
Society (organic chemistry division) for young
researchers in 2006. Author of 107 papers, 1
book (RSC), 12 chapters, 1 patent, on the
synthesis of nitrogen glycomimetics and new
green oxidation methods.
Camilla Matassini, RTD-B of the University of
Florence since 2022. Doctor Europaeus in
Chemical Sciences in 2014. In 2016 she
received the "Accademia dei Lincei" award in
the field of Synthetic Organic Chemistry and in
2020 the SCI Research Award "Organic
Chemistry for Life Sciences- Junior ". Author of
40 papers, 1 patent, 2 book chapters, on
synthesis of mono- and multivalent immino
sugars, gold nanoparticles, development of
pharmacological chaperones.
Camilla Parmeggiani, Associate Professor at
the University of Florence since 2021. PhD in
Chemical Sciences in 2010. LENS Associate
since 2010. Received Research Award
"Organic Chemistry for the Environment,
Energy and Nanosciences" (Division of
Organic Chemistry, SCI) in 2016. She has
authored 56 papers, 3 chapters, 4 patents (h-
index 29), on smart materials, nitrogen
glycomimetics and new green oxidation
methods.
Andrea Goti, Full Professor at the University of
Florence since 2002. Awarded the 2020
"Adolfo Quilico" Medal by the Division of
Organic Chemistry of the Italian Chemical
Society. He has authored 200 publications on
new green synthetic methodologies, pericyclic
reactions, synthesis of heterocycles and
nitrogen glycomimetics.
Giampiero D'Adamio, R&D in Fabo Tape
Solutions, a leading international
manufacturer of adhesive tapes. Research
fellow at the University of Florence from 2011
to 2016 in the synthesis of nitrogen
glycomimetics. In 2017 he obtained a PhD
degree in Chemical Sciences specializing in
the development of multivalent immino
sugars. Author of 16 publications and co-
author of one patent.
Serena Catarzi, executive biologist SOS of
Clinical Pathology, San Giovanni di Dio Hospital
- Florence. PhD in Clinical Biochemistry in 2003.
Author of 26 publications and 1 patent.
Amelia Morrone, associate professorat the
University of Florence since 2015. Head of
Laboratory of Molecular Biology of
Neurometabolic Diseases, AOU Meyer,
Florence. PhD in Neurometabolic Sciences
in 1994. Specialization in Medical Genetics
in 1997 and in Biochemistry and Clinical
Chemistry in 2002. Author of more than
130 papers and 2 chapters on lysosomal
storage diseases and other neurometabolic
diseases
5. The patented technology has been tested in the following case studies:
1. Pharmacological chaperones for Morquio A;
2. Combined ERT/PC therapy for Morquio A;
3. Combined ERT/PC therapy for Hunter's disease.
Pharmacological chaperone (PC)-based therapies have multiple advantages including, the possibility of oral administration,
restoration of endogenous enzyme activity, and low cost of therapy; in addition, dendrimeric immino sugars can also be
used in combined ERT/PC therapy as recombinant enzyme stabilizers.
Industrial application
6. Possible
developments
The patent is available for outright assignment, as well as for exclusive and non-exclusive licensing.
Licenses are available for the remaining term of the patent titles.
The Research Group is available for new collaborative and third-party research activities, in-depth
technical investigations, scientific advice, also aimed at raising the TRL of the technology.
The TRL of the invention is 3.
7. Ufficio di Trasferimento Tecnologico dell’Università degli Studi di Firenze
Sede: Piazza S. Marco 4 – 50121 Firenze
Sito web: www.unifi.it
E-mail: brevetti@unifi.it
For further information:
Ufficio Regionale di Trasferimento Tecnologico
Sede: Via Luigi Carlo Farini, 8 50121 Firenze (FI)
E-mail: urtt@regione.toscana.it
For further information: