Neurofibroma stimulates salivary gland neoplasm - case report
•Download as PPTX, PDF•
0 likes•25 views
This document presents a case report of a 23-year-old male with a solitary neurofibroma on the hard palate that mimicked a salivary gland neoplasm. Histopathological examination of the excised tissue showed features of a neurofibroma including abundant spindle cells positive for vimentin, CD34, and S100. A diagnosis of solitary neurofibroma was made, and no recurrence was observed on follow-up visits. Neurofibromas can be difficult to diagnose and require clinical, histological, and immunohistochemical examination to differentiate from other spindle cell tumors.
Report
Share
Report
Share
Recommended
Neuro fibroma
Neurofibroma is a benign tumor that arises from the connective tissue of nerves. It consists of neural and fibrous elements. Neurofibromas can be single or multiple, and form fusiform swellings along nerves. They can occur in cranial, spinal, or peripheral nerves. The main types are nodular, plexiform, generalized (von Recklinghausen's disease), elephantiatic, and pachydermatocoele. Nodular neurofibromas commonly affect peripheral nerves in adults as single, firm nodules. Plexiform neurofibromas often involve the face and can cause vision problems or bone erosion. Generalized neurofibromatosis is an inherited condition with
Neurofibroma
Neurofibroma - A neurofibroma is a type of nerve tumor that forms soft bumps on or under the skin.
It occurs in approximately 1 in 4,000 births
It is a genetic disorder that can affect the brain, spinal cord, nerves and skin
Tumors arising from nerve tissue & fat tissue in bones
Neurofibromas are benign peripheral nerve sheath tumors that are the most common manifestation of neurofibromatosis type 1 (NF1). They typically present in young adults as slow-growing, solitary masses under 5cm located on superficial cutaneous nerves of the head and neck. Neurofibromas associated with NF1 can be diffuse, involving long nerve segments beyond the epineurium. Imaging shows well-defined hypodense masses on CT without enhancement, and hyperintense lesions on T2-weighted MRI with heterogeneous enhancement. Lipomas are benign fatty tumors that most commonly involve the long bones, presenting as osteolytic lesions on plain films.
Neural tumors
This document provides an overview of tumors of peripheral nerves. It begins with an introduction classifying peripheral nerve tumors and noting their most common sites in the oral region. It then describes several benign nerve tumors in detail, including traumatic neuroma, palisaded encapsulated neuroma, mucosal neuroma, neurofibroma/neurofibromatosis, schwannoma, and granular cell tumor. It also briefly mentions other rare benign nerve tumors. The document concludes by listing and defining some malignant peripheral nerve tumors. In summary, it comprehensively reviews the classification, clinical features, pathology, and characteristics of both benign and malignant peripheral nerve tumors.
01.benign tumors of neural origin
1. Neurilemomas are benign tumors originating from Schwann cells covering peripheral nerves. They commonly occur in the mandible and sacrum and cause swelling but rarely pain unless encroaching on nerves. Imaging shows well-defined margins and expansion of the inferior alveolar nerve canal.
2. Neuromas are reactive hyperplasias resulting from nerve damage that can cause severe pain. Imaging shows proliferation within bone canals of the mandible.
3. Neurofibromas involve proliferation of Schwann cells, axons, and nerve sheath tissue. They may expand bone and cause pain or paresthesia. Imaging shows expansion of the inferior dental nerve canal.
TOLOSA HUNT SYNDROME
A 53-year-old female presented with a 4-month history of left periorbital headache and frontal parasthesia. Imaging showed a 1cm enhancing lesion in the cavernous sinus. She was initially treated for tuberculosis but did not improve. Further workup revealed positive Mantoux test but negative CSF studies. Her symptoms improved 90% with a short course of antibiotics and steroids. The differential diagnosis includes cavernous sinus syndrome such as Tolosa-Hunt syndrome, an idiopathic inflammatory condition. A repeat MRI after treatment showed reduction in the size of the lesion, consistent with inflammatory pseudotumor.
Olfactory neuroblastoma
Olfactory neuroblastoma is a rare cancer that arises from the olfactory nerve in the nasal cavity. The patient, a 46-year-old female, presented with bleeding from the left nasal cavity and was found to have a neuroendocrine tumor based on a biopsy. Further testing confirmed the diagnosis of olfactory neuroblastoma. Treatment involves surgical excision followed by radiation therapy. Prognosis depends on staging, with 5-year survival rates of 80% for early-stage disease treated aggressively.
Imaging of neurocutaneous syndrome overview
This document discusses imaging findings in various neurocutaneous syndromes. It begins with an introduction to neurocutaneous syndromes as multisystem disorders involving the ectoderm. Several specific syndromes are then discussed in more detail, including their diagnostic criteria and common neuroimaging findings. Neurofibromatosis Type 1, Neurofibromatosis Type 2, Sturge-Weber syndrome, and Dyke-Davidoff-Masson syndrome are some of the syndromes covered. For each, characteristic lesions, abnormalities, and imaging appearances are described. Examples of imaging findings from case studies are also presented.
Recommended
Neuro fibroma
Neurofibroma is a benign tumor that arises from the connective tissue of nerves. It consists of neural and fibrous elements. Neurofibromas can be single or multiple, and form fusiform swellings along nerves. They can occur in cranial, spinal, or peripheral nerves. The main types are nodular, plexiform, generalized (von Recklinghausen's disease), elephantiatic, and pachydermatocoele. Nodular neurofibromas commonly affect peripheral nerves in adults as single, firm nodules. Plexiform neurofibromas often involve the face and can cause vision problems or bone erosion. Generalized neurofibromatosis is an inherited condition with
Neurofibroma
Neurofibroma - A neurofibroma is a type of nerve tumor that forms soft bumps on or under the skin.
It occurs in approximately 1 in 4,000 births
It is a genetic disorder that can affect the brain, spinal cord, nerves and skin
Tumors arising from nerve tissue & fat tissue in bones
Neurofibromas are benign peripheral nerve sheath tumors that are the most common manifestation of neurofibromatosis type 1 (NF1). They typically present in young adults as slow-growing, solitary masses under 5cm located on superficial cutaneous nerves of the head and neck. Neurofibromas associated with NF1 can be diffuse, involving long nerve segments beyond the epineurium. Imaging shows well-defined hypodense masses on CT without enhancement, and hyperintense lesions on T2-weighted MRI with heterogeneous enhancement. Lipomas are benign fatty tumors that most commonly involve the long bones, presenting as osteolytic lesions on plain films.
Neural tumors
This document provides an overview of tumors of peripheral nerves. It begins with an introduction classifying peripheral nerve tumors and noting their most common sites in the oral region. It then describes several benign nerve tumors in detail, including traumatic neuroma, palisaded encapsulated neuroma, mucosal neuroma, neurofibroma/neurofibromatosis, schwannoma, and granular cell tumor. It also briefly mentions other rare benign nerve tumors. The document concludes by listing and defining some malignant peripheral nerve tumors. In summary, it comprehensively reviews the classification, clinical features, pathology, and characteristics of both benign and malignant peripheral nerve tumors.
01.benign tumors of neural origin
1. Neurilemomas are benign tumors originating from Schwann cells covering peripheral nerves. They commonly occur in the mandible and sacrum and cause swelling but rarely pain unless encroaching on nerves. Imaging shows well-defined margins and expansion of the inferior alveolar nerve canal.
2. Neuromas are reactive hyperplasias resulting from nerve damage that can cause severe pain. Imaging shows proliferation within bone canals of the mandible.
3. Neurofibromas involve proliferation of Schwann cells, axons, and nerve sheath tissue. They may expand bone and cause pain or paresthesia. Imaging shows expansion of the inferior dental nerve canal.
TOLOSA HUNT SYNDROME
A 53-year-old female presented with a 4-month history of left periorbital headache and frontal parasthesia. Imaging showed a 1cm enhancing lesion in the cavernous sinus. She was initially treated for tuberculosis but did not improve. Further workup revealed positive Mantoux test but negative CSF studies. Her symptoms improved 90% with a short course of antibiotics and steroids. The differential diagnosis includes cavernous sinus syndrome such as Tolosa-Hunt syndrome, an idiopathic inflammatory condition. A repeat MRI after treatment showed reduction in the size of the lesion, consistent with inflammatory pseudotumor.
Olfactory neuroblastoma
Olfactory neuroblastoma is a rare cancer that arises from the olfactory nerve in the nasal cavity. The patient, a 46-year-old female, presented with bleeding from the left nasal cavity and was found to have a neuroendocrine tumor based on a biopsy. Further testing confirmed the diagnosis of olfactory neuroblastoma. Treatment involves surgical excision followed by radiation therapy. Prognosis depends on staging, with 5-year survival rates of 80% for early-stage disease treated aggressively.
Imaging of neurocutaneous syndrome overview
This document discusses imaging findings in various neurocutaneous syndromes. It begins with an introduction to neurocutaneous syndromes as multisystem disorders involving the ectoderm. Several specific syndromes are then discussed in more detail, including their diagnostic criteria and common neuroimaging findings. Neurofibromatosis Type 1, Neurofibromatosis Type 2, Sturge-Weber syndrome, and Dyke-Davidoff-Masson syndrome are some of the syndromes covered. For each, characteristic lesions, abnormalities, and imaging appearances are described. Examples of imaging findings from case studies are also presented.
Topic of the month...Neuromyelitis optica
This document provides an overview of neuromyelitis optica (NMO), including:
- The history of NMO and debates around whether it is a distinct disease or subtype of multiple sclerosis. Early case reports and reviews are discussed.
- Clinical features of NMO from case series, including most patients being women with average age of onset of 37, presentations involving optic neuritis, transverse myelitis or both, and courses being monophasic or polyphasic.
- Diagnostic criteria that have been proposed for NMO, including challenges given the variable clinical presentations and features that can overlap with other conditions.
Case record...Neuromyelitis optica
- A 15-year-old female developed left-sided optic neuritis followed by transverse myelitis months later. MRI showed periventricular white matter changes atypical for multiple sclerosis.
- The patient was diagnosed with neuromyelitis optica (Devic's disease), a disorder characterized by inflammation of the optic nerve and spinal cord. It is identified by longitudinally extensive spinal cord lesions on MRI and seropositivity for neuromyelitis optica immunoglobulin G.
- Acute transverse myelitis is an inflammatory disorder of the spinal cord that can have various causes, including infections, autoimmune disorders, and neuromyelitis optica. It is characterized clinically by motor,
Glossopharyngeal neuralgia presentation
This document provides information about glossopharyngeal neuralgia (GPN), including its:
- Anatomy involving branches to the tongue, throat, tonsil, ear, and carotid body
- Symptoms of severe throat and ear pain triggered by various actions
- Causes such as nerve damage from blood vessels, tumors, infections, or compression
- Diagnosis through patient history and tests to rule out other conditions
- Treatment options including medications, microvascular decompression surgery, and nerve ablation procedures to relieve pain
Neurofibromatosis and the spine
This document discusses neurofibromatosis and its effects on the spine. Neurofibromatosis is a genetic disorder that can cause tumors to grow along nerves. There are four main types, with neurofibromatosis type 1 being the most common. Spinal deformities are a frequent complication, with scoliosis occurring in 10-20% of NF1 patients. Scoliosis can be classified as dystrophic or non-dystrophic based on x-ray and MRI findings. Treatment depends on the type and severity of the curve and may involve observation, bracing, surgery, or a combination. Post-operative immobilization is recommended to allow for fusion. Complications can include pseudoarthrosis, paraplegia
Neurofibromatosis
This document discusses neurofibromatosis, a genetic disorder characterized by tumors that grow on nerve tissues. There are two main types, NF1 and NF2. NF1 is more common and causes café-au-lait spots, tumors on nerves and in the brain, and skeletal abnormalities. NF2 causes tumors on cranial and spinal nerves that can lead to hearing loss. Both have no cure and are managed through monitoring for complications and using surgery, chemotherapy or radiation to treat tumors causing issues. Diagnosis involves examining for characteristic physical signs like skin lesions or tumors.
Neurocutaneous syndromes
This document provides an overview of tuberous sclerosis complex (TSC), a genetic disorder characterized by benign tumors that grow in various organs. Some key points:
1. TSC is caused by mutations in either the TSC1 or TSC2 gene and is inherited in an autosomal dominant pattern.
2. Clinical features include facial angiofibromas, epilepsy, and mental retardation known as the "triad" of TSC. Other features are skin lesions, seizures, and tumors in the brain, heart, kidneys, and other organs.
3. Pathology involves benign tumors called tubers that form in the brain and other tissues due to abnormal cell growth. Diagnosis is based
NEUROFIBROMATOSIS TYPE I /prosthodontic courses
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.
18. neurofibromatosis muhammad abdelghani
Neurofibromatosis is a genetic disorder that affects the nervous system and causes tumors to form on nerves. There are two main types: type 1 causes skin abnormalities and tumors under the skin or deep tissues; type 2 causes tumors of the brain or spinal cord. Symptoms can include bone and spinal deformities, limb length differences, and high risk of cancer. Treatment depends on the specific manifestations but may include surgery to remove tumors, bone grafts to repair fractures, or limb lengthening procedures.
Tuberculosis of spine and its complications nishanth
This document discusses tuberculosis of the spine (Pott's disease). It is a tertiary lesion caused by bloodborne tuberculosis infection settling in the vertebral body, causing inflammation and granuloma formation. This can lead to caseous necrosis, abscess formation, and bone and disc destruction. Clinical features include back pain, stiffness, deformity, and potentially paraplegia. Diagnosis involves radiological exams showing vertebral body destruction and abscesses. Treatment involves anti-tubercular therapy along with spinal immobilization and surgery if needed to decompress the spinal cord in cases of paraplegia.
Presentation1
The document discusses the epidemiology, clinical presentation, investigations, management, and complications of tuberculosis of the spine. It provides details on the typical presentation of spinal TB, including symptoms, radiographic features at different stages, and classifications. Risk factors, investigations like imaging and biopsy, medical management with antitubercular therapy, and indications for surgical treatment are also outlined.
Tuberculosis of spine
General and simple presentation of tuberculosis of spine on incidence, pathology, complications, management. This presentation is suitable for PGs, Ugs.
spinal tuberculosis, potts spine, tb spine, caries spine,
spine infection, kyphosis
Cervical cord compression
The document discusses cervical spondylotic myelopathy, a spinal cord injury caused by compression of the spinal cord from age-related wear and tear changes in the cervical spine. An MRI of the cervical spine showed a disc protrusion at the C3/C4 level that was causing spinal stenosis, narrowing of the spinal canal and pressing on the spinal cord. The MRI also revealed increased fluid signal within the spinal cord without any abnormality in the cord's natural signal, indicating injury from compression.
Mri evaluation of spine myelopathy
This document discusses various demyelinating diseases of the central nervous system that can present with myelopathy, including multiple sclerosis (MS), neuromyelitis optica (NMO), acute disseminated encephalomyelitis (ADEM), transverse myelitis (TM), and others. It provides details on the typical MRI findings and locations of lesions for each disease. Key differences between MS and NMO are described, such as the typical involvement of the brainstem and basal ganglia in ADEM compared to MS. The document also outlines distinguishing imaging features between these conditions and other mimics like small vessel disease, tumors, and arterial infarction.
Schwannoma
Schwannoma is a benign tumor that develops from Schwann cells covering nerves. It most commonly involves cranial nerves VIII (acoustic neuroma) and V. Symptoms depend on the affected nerve but may include hearing loss, dizziness, facial numbness, and headaches. Schwannomas typically appear iso- to hypointense on T1-weighted MRI and hyperintense on T2-weighted MRI, demonstrating intense contrast enhancement. Surgery is the primary treatment and prognosis is generally good, with low recurrence risk even after complete resection.
Short case...Congenital syringomyelia
This document describes a case of congenital syringomyelia as seen on MRI imaging. It includes 4 figures showing MRI images of the cervical and upper dorsal spinal cord revealing a longitudinal syringomyelic cavity involving the central canal with herniation of the cerebellar tonsils. The key characteristics that indicate this is a congenital subtype include the presence of Arnold-Chiari malformation, a central cavity location representing dilation of the central canal, involvement of the cervico-dorsal region, and MRI signal matching CSF. A table compares features of congenital vs neoplastic syringomyelia.
Syringomyelia
This document provides an overview of syringomyelia, including:
- It is a spinal cord cavity filled with cerebrospinal fluid, with a prevalence of 9 per 100,000 people.
- It can be caused by traumatic injury, Chiari malformation, or other craniovertebral junction anomalies.
- Symptoms depend on the location and extent of the syrinx and can include sensory loss, weakness, pain, and autonomic dysfunction.
- Magnetic resonance imaging is the best way to diagnose and assess syringomyelia.
- Treatment may involve surgery to decompress the craniovertebral junction, open the syrinx, or place a shunt
Olfactory neuroblastoma-(esthesioneuroblastoma)-following-retro-orbital-irrad...
This case report describes a patient who developed olfactory neuroblastoma 8 years after receiving radiation therapy for Graves' ophthalmopathy. The patient underwent surgery followed by reduced-dose radiation therapy and chemotherapy due to his previous radiation exposure. Despite this, he tolerated treatment well without excessive toxicity. Now 12 years later, the patient remains in remission without evidence of recurrence. A review of the literature found 4 other cases of radiation-induced olfactory neuroblastoma, suggesting prior radiation therapy is a risk factor. Outcomes of radiation-induced disease appear generally poorer but are highly variable.
Pott Disease
Pott's disease, or spinal tuberculosis, is caused by Mycobacterium tuberculosis infection of the spine. It was first described by Percivall Pott in 1779. Key points:
1) India has a high prevalence of tuberculosis, with an estimated 2 million cases of spinal TB.
2) Spinal TB most commonly involves the thoracic spine, followed by the lumbar, cervical, and sacral regions.
3) Diagnosis is made through clinical history, physical exam, tuberculin skin test, imaging like x-rays, CT, and MRI showing vertebral body destruction and abscess formation.
Neurofibromatosis abhijeet
Neurofibromatosis is a genetically inherited disorder that causes tumors to grow on nerve tissues. There are three main types: NF1 is the most common, caused by a mutation on chromosome 17 and characterized by cafe au lait spots and benign nerve tumors; NF2 results from a mutation on chromosome 22 and causes bilateral tumors of the vestibular nerve; schwannomatosis involves mutations on chromosomes 17 and 22 and causes tumors on cranial, spinal and peripheral nerves without hearing loss. Symptoms vary but can include discolored skin patches, nerve tumors, headaches, hearing loss, and in rare cases cancer. Diagnosis is based on clinical criteria and treatment focuses on managing symptoms through surgery or chemotherapy.
Phakomatoses ppt
The document defines phakomatoses as multisystem disorders involving the central nervous system, eyes, and skin that cause characteristic lesions and hamartomas. It then describes several common and uncommon phakomatoses syndromes in detail, focusing on their defining clinical features, inheritance patterns, prevalence, and ocular manifestations. The most prominent syndromes discussed are neurofibromatosis types 1 and 2, tuberous sclerosis, Von Hippel-Lindau disease, Sturge-Weber syndrome, and Wyburn-Mason syndrome.
Benign and malignant nerve sheath tumors
This document summarizes benign and malignant nerve sheath tumors. It describes neurofibroma as a common benign peripheral nerve tumor that can be solitary or associated with neurofibromatosis. Schwannoma is another benign nerve sheath tumor that arises from Schwann cells. Malignant peripheral nerve sheath tumor is described as a rare malignant schwannoma that commonly affects young adults and is associated with rapid growth and nerve deficits. The document provides details on clinical features, histopathology, treatment and prognosis of these nerve sheath tumors.
Neurocutaneous Disorders Walid Reda Ashour Egypt
This document discusses several neurocutaneous disorders including neurofibromatosis, tuberous sclerosis, Sturge-Weber syndrome, xeroderma pigmentosum, ataxia-telangiectasia, Cockayne's syndrome, and Von Hippel-Lindau disease. These disorders are characterized by abnormalities affecting the skin, brain, and other organs that develop due to genetic mutations affecting tissues of ectodermal origin. The document provides details on the clinical features, diagnosis, and treatment of each condition.
More Related Content
What's hot
Topic of the month...Neuromyelitis optica
This document provides an overview of neuromyelitis optica (NMO), including:
- The history of NMO and debates around whether it is a distinct disease or subtype of multiple sclerosis. Early case reports and reviews are discussed.
- Clinical features of NMO from case series, including most patients being women with average age of onset of 37, presentations involving optic neuritis, transverse myelitis or both, and courses being monophasic or polyphasic.
- Diagnostic criteria that have been proposed for NMO, including challenges given the variable clinical presentations and features that can overlap with other conditions.
Case record...Neuromyelitis optica
- A 15-year-old female developed left-sided optic neuritis followed by transverse myelitis months later. MRI showed periventricular white matter changes atypical for multiple sclerosis.
- The patient was diagnosed with neuromyelitis optica (Devic's disease), a disorder characterized by inflammation of the optic nerve and spinal cord. It is identified by longitudinally extensive spinal cord lesions on MRI and seropositivity for neuromyelitis optica immunoglobulin G.
- Acute transverse myelitis is an inflammatory disorder of the spinal cord that can have various causes, including infections, autoimmune disorders, and neuromyelitis optica. It is characterized clinically by motor,
Glossopharyngeal neuralgia presentation
This document provides information about glossopharyngeal neuralgia (GPN), including its:
- Anatomy involving branches to the tongue, throat, tonsil, ear, and carotid body
- Symptoms of severe throat and ear pain triggered by various actions
- Causes such as nerve damage from blood vessels, tumors, infections, or compression
- Diagnosis through patient history and tests to rule out other conditions
- Treatment options including medications, microvascular decompression surgery, and nerve ablation procedures to relieve pain
Neurofibromatosis and the spine
This document discusses neurofibromatosis and its effects on the spine. Neurofibromatosis is a genetic disorder that can cause tumors to grow along nerves. There are four main types, with neurofibromatosis type 1 being the most common. Spinal deformities are a frequent complication, with scoliosis occurring in 10-20% of NF1 patients. Scoliosis can be classified as dystrophic or non-dystrophic based on x-ray and MRI findings. Treatment depends on the type and severity of the curve and may involve observation, bracing, surgery, or a combination. Post-operative immobilization is recommended to allow for fusion. Complications can include pseudoarthrosis, paraplegia
Neurofibromatosis
This document discusses neurofibromatosis, a genetic disorder characterized by tumors that grow on nerve tissues. There are two main types, NF1 and NF2. NF1 is more common and causes café-au-lait spots, tumors on nerves and in the brain, and skeletal abnormalities. NF2 causes tumors on cranial and spinal nerves that can lead to hearing loss. Both have no cure and are managed through monitoring for complications and using surgery, chemotherapy or radiation to treat tumors causing issues. Diagnosis involves examining for characteristic physical signs like skin lesions or tumors.
Neurocutaneous syndromes
This document provides an overview of tuberous sclerosis complex (TSC), a genetic disorder characterized by benign tumors that grow in various organs. Some key points:
1. TSC is caused by mutations in either the TSC1 or TSC2 gene and is inherited in an autosomal dominant pattern.
2. Clinical features include facial angiofibromas, epilepsy, and mental retardation known as the "triad" of TSC. Other features are skin lesions, seizures, and tumors in the brain, heart, kidneys, and other organs.
3. Pathology involves benign tumors called tubers that form in the brain and other tissues due to abnormal cell growth. Diagnosis is based
NEUROFIBROMATOSIS TYPE I /prosthodontic courses
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.
18. neurofibromatosis muhammad abdelghani
Neurofibromatosis is a genetic disorder that affects the nervous system and causes tumors to form on nerves. There are two main types: type 1 causes skin abnormalities and tumors under the skin or deep tissues; type 2 causes tumors of the brain or spinal cord. Symptoms can include bone and spinal deformities, limb length differences, and high risk of cancer. Treatment depends on the specific manifestations but may include surgery to remove tumors, bone grafts to repair fractures, or limb lengthening procedures.
Tuberculosis of spine and its complications nishanth
This document discusses tuberculosis of the spine (Pott's disease). It is a tertiary lesion caused by bloodborne tuberculosis infection settling in the vertebral body, causing inflammation and granuloma formation. This can lead to caseous necrosis, abscess formation, and bone and disc destruction. Clinical features include back pain, stiffness, deformity, and potentially paraplegia. Diagnosis involves radiological exams showing vertebral body destruction and abscesses. Treatment involves anti-tubercular therapy along with spinal immobilization and surgery if needed to decompress the spinal cord in cases of paraplegia.
Presentation1
The document discusses the epidemiology, clinical presentation, investigations, management, and complications of tuberculosis of the spine. It provides details on the typical presentation of spinal TB, including symptoms, radiographic features at different stages, and classifications. Risk factors, investigations like imaging and biopsy, medical management with antitubercular therapy, and indications for surgical treatment are also outlined.
Tuberculosis of spine
General and simple presentation of tuberculosis of spine on incidence, pathology, complications, management. This presentation is suitable for PGs, Ugs.
spinal tuberculosis, potts spine, tb spine, caries spine,
spine infection, kyphosis
Cervical cord compression
The document discusses cervical spondylotic myelopathy, a spinal cord injury caused by compression of the spinal cord from age-related wear and tear changes in the cervical spine. An MRI of the cervical spine showed a disc protrusion at the C3/C4 level that was causing spinal stenosis, narrowing of the spinal canal and pressing on the spinal cord. The MRI also revealed increased fluid signal within the spinal cord without any abnormality in the cord's natural signal, indicating injury from compression.
Mri evaluation of spine myelopathy
This document discusses various demyelinating diseases of the central nervous system that can present with myelopathy, including multiple sclerosis (MS), neuromyelitis optica (NMO), acute disseminated encephalomyelitis (ADEM), transverse myelitis (TM), and others. It provides details on the typical MRI findings and locations of lesions for each disease. Key differences between MS and NMO are described, such as the typical involvement of the brainstem and basal ganglia in ADEM compared to MS. The document also outlines distinguishing imaging features between these conditions and other mimics like small vessel disease, tumors, and arterial infarction.
Schwannoma
Schwannoma is a benign tumor that develops from Schwann cells covering nerves. It most commonly involves cranial nerves VIII (acoustic neuroma) and V. Symptoms depend on the affected nerve but may include hearing loss, dizziness, facial numbness, and headaches. Schwannomas typically appear iso- to hypointense on T1-weighted MRI and hyperintense on T2-weighted MRI, demonstrating intense contrast enhancement. Surgery is the primary treatment and prognosis is generally good, with low recurrence risk even after complete resection.
Short case...Congenital syringomyelia
This document describes a case of congenital syringomyelia as seen on MRI imaging. It includes 4 figures showing MRI images of the cervical and upper dorsal spinal cord revealing a longitudinal syringomyelic cavity involving the central canal with herniation of the cerebellar tonsils. The key characteristics that indicate this is a congenital subtype include the presence of Arnold-Chiari malformation, a central cavity location representing dilation of the central canal, involvement of the cervico-dorsal region, and MRI signal matching CSF. A table compares features of congenital vs neoplastic syringomyelia.
Syringomyelia
This document provides an overview of syringomyelia, including:
- It is a spinal cord cavity filled with cerebrospinal fluid, with a prevalence of 9 per 100,000 people.
- It can be caused by traumatic injury, Chiari malformation, or other craniovertebral junction anomalies.
- Symptoms depend on the location and extent of the syrinx and can include sensory loss, weakness, pain, and autonomic dysfunction.
- Magnetic resonance imaging is the best way to diagnose and assess syringomyelia.
- Treatment may involve surgery to decompress the craniovertebral junction, open the syrinx, or place a shunt
Olfactory neuroblastoma-(esthesioneuroblastoma)-following-retro-orbital-irrad...
This case report describes a patient who developed olfactory neuroblastoma 8 years after receiving radiation therapy for Graves' ophthalmopathy. The patient underwent surgery followed by reduced-dose radiation therapy and chemotherapy due to his previous radiation exposure. Despite this, he tolerated treatment well without excessive toxicity. Now 12 years later, the patient remains in remission without evidence of recurrence. A review of the literature found 4 other cases of radiation-induced olfactory neuroblastoma, suggesting prior radiation therapy is a risk factor. Outcomes of radiation-induced disease appear generally poorer but are highly variable.
Pott Disease
Pott's disease, or spinal tuberculosis, is caused by Mycobacterium tuberculosis infection of the spine. It was first described by Percivall Pott in 1779. Key points:
1) India has a high prevalence of tuberculosis, with an estimated 2 million cases of spinal TB.
2) Spinal TB most commonly involves the thoracic spine, followed by the lumbar, cervical, and sacral regions.
3) Diagnosis is made through clinical history, physical exam, tuberculin skin test, imaging like x-rays, CT, and MRI showing vertebral body destruction and abscess formation.
Neurofibromatosis abhijeet
Neurofibromatosis is a genetically inherited disorder that causes tumors to grow on nerve tissues. There are three main types: NF1 is the most common, caused by a mutation on chromosome 17 and characterized by cafe au lait spots and benign nerve tumors; NF2 results from a mutation on chromosome 22 and causes bilateral tumors of the vestibular nerve; schwannomatosis involves mutations on chromosomes 17 and 22 and causes tumors on cranial, spinal and peripheral nerves without hearing loss. Symptoms vary but can include discolored skin patches, nerve tumors, headaches, hearing loss, and in rare cases cancer. Diagnosis is based on clinical criteria and treatment focuses on managing symptoms through surgery or chemotherapy.
Phakomatoses ppt
The document defines phakomatoses as multisystem disorders involving the central nervous system, eyes, and skin that cause characteristic lesions and hamartomas. It then describes several common and uncommon phakomatoses syndromes in detail, focusing on their defining clinical features, inheritance patterns, prevalence, and ocular manifestations. The most prominent syndromes discussed are neurofibromatosis types 1 and 2, tuberous sclerosis, Von Hippel-Lindau disease, Sturge-Weber syndrome, and Wyburn-Mason syndrome.
What's hot (20)
Tuberculosis of spine and its complications nishanth
Tuberculosis of spine and its complications nishanth
Olfactory neuroblastoma-(esthesioneuroblastoma)-following-retro-orbital-irrad...
Olfactory neuroblastoma-(esthesioneuroblastoma)-following-retro-orbital-irrad...
Similar to Neurofibroma stimulates salivary gland neoplasm - case report
Benign and malignant nerve sheath tumors
This document summarizes benign and malignant nerve sheath tumors. It describes neurofibroma as a common benign peripheral nerve tumor that can be solitary or associated with neurofibromatosis. Schwannoma is another benign nerve sheath tumor that arises from Schwann cells. Malignant peripheral nerve sheath tumor is described as a rare malignant schwannoma that commonly affects young adults and is associated with rapid growth and nerve deficits. The document provides details on clinical features, histopathology, treatment and prognosis of these nerve sheath tumors.
Neurocutaneous Disorders Walid Reda Ashour Egypt
This document discusses several neurocutaneous disorders including neurofibromatosis, tuberous sclerosis, Sturge-Weber syndrome, xeroderma pigmentosum, ataxia-telangiectasia, Cockayne's syndrome, and Von Hippel-Lindau disease. These disorders are characterized by abnormalities affecting the skin, brain, and other organs that develop due to genetic mutations affecting tissues of ectodermal origin. The document provides details on the clinical features, diagnosis, and treatment of each condition.
peripheral nerve tumors.pptx
This document discusses benign and malignant tumors of the peripheral nerve. It begins by introducing peripheral nerve sheath tumors (PNSTs) which arise from the nerve sheath, and peripheral non-neural sheath tumors which do not. Specific benign tumor types are then discussed in more detail, including schwannomas, neurofibromas, perineuriomas, desmoid tumors, and ganglion cysts. For each tumor type, information is provided on clinical presentation, histology, imaging characteristics, diagnosis, and surgical approach.
A Review on Neurosarcoidosis Dec 21, 2016
This document provides a review of neurosarcoidosis. It begins with defining sarcoidosis and neurosarcoidosis as involving non-caseating granulomas in the nervous system. It then discusses the epidemiology, clinical manifestations such as cranial neuropathies and meningitis, diagnostic criteria including biopsy evidence, and treatment primarily with corticosteroids. The review concludes with highlighting the challenges of diagnosing and managing neurosarcoidosis given the lack of randomized controlled trials and importance of raising awareness of this condition.
plasmacytoma-1
This document presents a case report of a 65-year-old female patient diagnosed with extramedullary plasmacytoma of the oral cavity. On examination, she had a lingual gingival growth involving her lower front teeth. Biopsies of the oral growth and a neck swelling found sheets of plasma cells confirming soft tissue plasmacytoma. Extramedullary plasmacytomas are rare neoplastic proliferations of plasma cells in soft tissue, accounting for 3% of plasma cell tumors. While prognosis is generally good, lifelong monitoring is needed to check for progression to multiple myeloma or new lesions.
Neurocutaneous syndrome
This document summarizes several phakomatoses, including neurofibromatosis types 1 and 2, tuberous sclerosis, ataxia-telangiectasia, and others. It describes key diagnostic criteria such as cafe-au-lait spots, freckling, and tumors. Common clinical features are neurological abnormalities, seizures, cognitive impairment, skin lesions, and increased cancer risk. Imaging and genetic testing can support diagnoses. Management involves symptomatic treatment and surveillance for complications. The disorders result from defects in cell differentiation and tumor suppression pathways.
Optic pathway glioma
This document discusses optic pathway gliomas and hypothalamic gliomas. It begins by defining optic pathway gliomas as tumors confined to the precortical visual pathway, sometimes involving the hypothalamus. Their location makes them surgically challenging to manage, and the optimal management is controversial. The document then covers the epidemiology, pathology, clinical presentation, imaging, differential diagnosis, natural history, and management options for these tumors, which include observation, surgery, chemotherapy and radiotherapy. Management depends on factors like age, presence of NF1, tumor location and size, and symptoms.
Pathology of intracranial tumors lecture
This document provides an overview of intracranial tumors, including:
1. It classifies intracranial neoplasms according to histological group and WHO grade and discusses some of the major tumor types such as astrocytic tumors, meningiomas, pituitary adenomas and others.
2. It reviews the epidemiology and pathogenesis of intracranial tumors. Most are sporadic but some have familial causes.
3. The objectives are for students to understand the classification, clinical manifestations, gross and microscopic features of common intracranial neoplasms.
Nasopharyngeal carcinoma2020
This document provides an overview of nasopharyngeal carcinoma (NPC), including its anatomy, epidemiology, etiology, pathology, classification, spread, clinical features, diagnosis, treatment, and differential diagnosis. NPC is most common in southern China and Taiwan. It is associated with genetic susceptibility and environmental factors like Epstein-Barr virus, air pollution, and salted fish consumption. The majority of NPC cases are undifferentiated carcinoma (WHO-3). Common symptoms include cervical lymphadenopathy and nasal symptoms. Diagnosis involves imaging, biopsy, and blood tests. Treatment options include radiotherapy alone or with chemotherapy, with concurrent chemoradiation being most effective for advanced stages.
Cysts of the jaw and neck
This document discusses and classifies various cysts of the jaws and neck. It describes 9 main odontogenic cysts including radicular, lateral periodontal, dentigerous, and calcifying odontogenic cysts. It also discusses non-odontogenic cysts such as nasolabial and nasopalatine canal cysts as well as pseudocysts like aneurysmal bone cyst and traumatic bone cyst. Finally, it summarizes 3 main soft tissue cysts of the neck - branchial, dermoid, and thyroglossal tract cysts.
Juvenile aggressive ossifying fibroma /prosthodontic course
The document describes a case study of a 12-year-old girl diagnosed with juvenile aggressive ossifying fibroma. She presented with a large swelling on the right side of her face that had been growing over the past 3 years. Imaging and biopsy revealed a benign bone tumor composed of proliferating fibroblastic tissue with psammoma-like cementum masses. The tumor involved the right maxillary sinus and other local structures. The patient underwent surgical removal of the tumor. Juvenile aggressive ossifying fibroma is a rare bone lesion that typically occurs in the jaw bones of children and can be difficult to diagnose due to variable presentation.
Neurocutaneous
This document provides an overview of several neurocutaneous syndromes:
- Neurofibromatosis causes tumors on nerves and affects 1 in 3,000 people. Common features include café-au-lait spots and tumors called neurofibromas.
- Tuberous sclerosis causes non-cancerous tumors in many organs and affects 1 in 6,000 people. Common signs include ash-leaf shaped skin lesions and seizures.
- Sturge-Weber syndrome is characterized by a birthmark on the face and abnormalities of blood vessels in the brain. It causes seizures and developmental delays.
JUVENILE NASOPHARYNGEAL ANGIOFIBROMA
This document discusses juvenile nasopharyngeal angiofibroma (JNA), a rare benign but invasive tumor that arises in adolescent males near the sphenopalatine foramen. JNA presents with nasal obstruction and epistaxis. Diagnosis involves imaging like CT and MRI to determine the extent of involvement. Treatment depends on staging and may include preoperative embolization, surgery such as endoscopic resection, or radiation for advanced cases. Complete resection aims to prevent recurrence while minimizing complications like bleeding, infection, and nerve damage.
Nasopharyngeal carcinoma2020
Nasopharyngeal carcinoma is a cancer that occurs in the nasopharynx, with the most common type being undifferentiated carcinoma. It has a strong association with Epstein-Barr virus. The incidence is highest in southern China and Southeast Asia. Common presenting symptoms include cervical lymph node enlargement, nasal obstruction, and ear symptoms. Diagnosis involves imaging such as CT or MRI along with biopsy. Treatment options include radiation therapy alone or with chemotherapy, with chemoradiation being the standard for locally advanced disease.
Case record...Neurofibromatosis type 1
This document discusses the case of a 16-year-old female patient with neurofibromatosis type 1 (NF1). The patient presented with vision problems, back pain, seizures, and learning difficulties. Imaging showed bilateral optic nerve gliomas and spinal tumors consistent with NF1. The document provides an overview of NF1, including diagnostic criteria involving café-au-lait spots, neurofibromas, and other clinical signs. Common complications of NF1 discussed include tumors, scoliosis, headaches, and learning disabilities.
Neurofibromatosis.pptx
Neurofibromatosis is a genetic disorder that causes tumors to form in nerve tissue. There are three main types: NF1, NF2, and schwannomatosis. NF1 is the most common type and is characterized by multiple café-au-lait spots and benign tumors called neurofibromas. The disorder is caused by mutations in the NF1 gene which codes for the neurofibromin protein. Clinical features include skin abnormalities, tumors of the nervous system, and bone abnormalities. Diagnosis is usually made clinically but genetic testing can help in some cases.
Neurofibroma of Nasal Cavity and Nasopharynx_Crimson Publishers
A 17-year-old male presented with progressive bilateral nasal obstruction, nasal discharge, headache, and hyposmia. Diagnostic nasal endoscopy revealed a firm, huge mass filling the bilateral posterior choana and attached to the posterior edge of the nasal septum. CT scan demonstrated a large soft-tissue density mass in the right nasal cavity extending into the right choana and nasopharynx. The mass was excised endoscopically and found to be a neurofibroma arising from the right nasal septum on histological examination. Neurofibroma is a rare benign peripheral nerve sheath tumor that can occur in the nasal cavity and paranasal sinuses. Complete surgical excision is usually curative for solitary neuro
Pyogenic granuloma
Histologically, the lesion shows a highly vascular proliferation that resembles granulation tissue.
Numerous small and larger endothelium-lined channels are formed that are engorged with red blood cells. These vessels sometimes are organized in lobular aggregates, and may be called as lobular capillary haemangioma.
The surface is usually ulcerated and replaced by a thick fibrinopurulent membrane.
A mixed inflammatory cell infiltrate of neutrophils, plasma cells, and lymphocytes is evident.
Neutrophils are most prevalent near the ulcerated surface; chronic inflammatory cells are found deeper in the specimen.
Ocular surface squamous neoplasia(ossn)
Ocular Surface Squamous Neoplasia (OSSN) is a spectrum of dysplastic and malignant epithelial lesions of the conjunctiva and cornea. It is most commonly caused by ultraviolet radiation exposure and can range from benign dysplasia to invasive squamous cell carcinoma. Clinical features may include elevated, variably shaped lesions near the limbus. Differential diagnosis includes pterygium, papilloma, and melanoma. Treatment involves surgical excision combined with cryotherapy or topical chemotherapy depending on size and invasiveness of the lesion.
Incontinentia pigmenti
This case report describes a newborn female with incontinentia pigmenti (IP). IP is a rare genetic condition characterized by skin lesions that appear in four stages. The newborn presented with diffuse blistering and bullae on her extremities and trunk arranged in a linear pattern. A skin biopsy showed features consistent with IP. She also experienced seizures. IP is caused by a defect on the X chromosome and predominantly affects females. It involves abnormalities in the skin, teeth, hair, eyes, and nervous system. Management focuses on monitoring for associated complications rather than treating the skin lesions directly.
Similar to Neurofibroma stimulates salivary gland neoplasm - case report (20)
Juvenile aggressive ossifying fibroma /prosthodontic course
Juvenile aggressive ossifying fibroma /prosthodontic course
Neurofibroma of Nasal Cavity and Nasopharynx_Crimson Publishers
Neurofibroma of Nasal Cavity and Nasopharynx_Crimson Publishers
More from Dr AJINS CB
Occlusion in Implants a Case Report
This document discusses occlusion in dental implants through three case reports. Case 1 describes implant failure due to excessive occlusal loads from new crowns. Case 2 describes peri-implant bone loss from traumatic occlusion resolved by a well-fitted overdenture. Case 3 describes early peri-implant bone loss from an occlusal discrepancy corrected through adjustment. The conclusion states that occlusion must be rigorously evaluated for implant prostheses as implants cannot compensate for faulty occlusion like natural teeth.
Bruxism and prosthetic treatment
This document reviews bruxism, its causes and effects, and implications for prosthodontic treatment. Bruxism is defined as involuntary teeth grinding and can be caused by emotional factors like stress. It can lead to tooth wear and failure of dental restorations. Management includes occlusal splints to protect teeth from grinding and adjusting restorations to minimize wear on opposing teeth. Prosthetic treatment needs to account for bruxism to improve retention and durability of restorations.
Preprosthetic Surgery
This document discusses preprosthetic surgery, which involves surgical procedures performed prior to placing a dental prosthesis in order to reshape and smooth ridges and eliminate hindrances. It describes common preprosthetic surgical procedures like alveoplasty and vestibuloplasty. It then presents a case study of an elderly edentulous patient who underwent quadrant-wise ridge correction surgery to achieve an optimal denture foundation. The surgery involved trimming irregular ridges and bony prominences. Post-operative healing was successful and minimized post-insertion denture problems. Preprosthetic surgery can thus aid in developing ridges to enable a comfortable, well-fitting prosthesis.
Flexible Removable Partial Dentures
Flexible removable partial dentures are made of thermoplastic resins like nylon that are more flexible than traditional acrylic partial dentures. They are easier to insert when there are undercuts in the dental arches. Flexible partial dentures distribute stress along the gums better than rigid partial dentures, causing less damage to oral tissues and greater comfort. While flexible dentures have advantages over traditional partial dentures, disadvantages include the potential for tooth detachment and staining over time.
Implant Supported Overdentures
This document discusses implant supported overdentures. It begins with an introduction defining implant supported overdentures. It then lists the indications and contraindications. The main advantages are improved stability, retention, support and reduced bone loss. The disadvantages include higher cost and need for proper hygiene. A case report is presented of a patient who received an implant supported mandibular overdenture. The treatment involved placing four implants in the mandible and attaching a ball attachment overdenture. Follow ups showed good outcomes and the conclusion states implant overdentures are a good treatment for edentulism.
Root Amputation and Perio Esthetic Surgery
This case report describes the successful treatment of a patient with gingival recession and root exposure on the upper right first premolar. Treatment involved non-surgical therapy followed by endodontic treatment, resection of the exposed buccal root, and perio-plastic surgery using a lateral pedicle flap and bone graft to cover the partially visible palatal root. At 1-year post-op, there was no further recession and the tooth was successfully salvaged, demonstrating that advanced perio-plastic procedures can restore esthetics and treat furcation involvement even in premolars.
Laser Induced Biostimulation
This document discusses laser induced biostimulation as a potential treatment for endo-perio lesions. It presents a case study of a patient with an endo-perio lesion on tooth #32 who was treated with both endodontic and periodontal procedures in the same appointment using a 980nm diode laser. The laser was used for canal disinfection, new attachment procedure and hemostasis. At the 1 month recall the patient was asymptomatic with healed sinus tract and reduced pocket depths. Follow-ups showed continued healing over 4 years. The conclusion is that laser treatment may be an effective way to simultaneously treat endo-perio lesions in a shorter time.
Nasopalatine duct cyst
1) The nasopalatine duct cyst originates from epithelial remnants of the nasopalatine duct and most commonly presents as a well-defined radiolucency in the midline of the anterior maxilla near the incisive foramen.
2) A 35-year-old male presented with a painless swelling over the palate that was diagnosed as a nasopalatine duct cyst based on radiographic and histological features.
3) The cyst was treated by surgical enucleation and recurrence is uncommon.
impressions in fpd
This document discusses various impression techniques used in fixed prosthodontics (FPD). It describes stock tray/putty wash, custom tray, closed bite, copper tube, and post space impression techniques. Advantages and disadvantages of each technique are provided. The document also presents a case report demonstrating the use of sectional impressions and custom trays to replace missing teeth, treating severe attrition. Combination impression techniques are described as easy and providing well-defined finish lines for multiple tooth restorations.
HEMISECTION
This document describes a case study of hemisection of the distal root of tooth 36 in a 46-year-old male patient with localized chronic periodontitis. The patient presented with pain and sensitivity in the left, lower, posterior region for 3 months. Intraoral examination revealed 13mm probing depth and grade III furcation involvement on tooth 36. Radiographs showed bone loss obliterating the distal root. After hemisection of the distal root and extraction, bone grafting was performed and the area healed well. At 8 months post-op, a fixed prosthesis involving teeth 35-38 was placed, restoring the hemisected tooth 36. The case study demonstrates that hemisection can be a conservative treatment
More from Dr AJINS CB (10)
Recently uploaded
Benner "Expanding Pathways to Publishing Careers"
This presentation was provided by Rebecca Benner, Ph.D., of the American Society of Anesthesiologists, for the second session of NISO's 2024 Training Series "DEIA in the Scholarly Landscape." Session Two: 'Expanding Pathways to Publishing Careers,' was held June 13, 2024.
Geography as a Discipline Chapter 1 __ Class 11 Geography NCERT _ Class Notes...
Geography as discipline
How Barcodes Can Be Leveraged Within Odoo 17
In this presentation, we will explore how barcodes can be leveraged within Odoo 17 to streamline our manufacturing processes. We will cover the configuration steps, how to utilize barcodes in different manufacturing scenarios, and the overall benefits of implementing this technology.
مصحف القراءات العشر أعد أحرف الخلاف سمير بسيوني.pdf
مصحف أحرف الخلاف للقراء العشرةأعد أحرف الخلاف بالتلوين وصلا سمير بسيوني غفر الله له
Philippine Edukasyong Pantahanan at Pangkabuhayan (EPP) Curriculum
(𝐓𝐋𝐄 𝟏𝟎𝟎) (𝐋𝐞𝐬𝐬𝐨𝐧 𝟏)-𝐏𝐫𝐞𝐥𝐢𝐦𝐬
𝐃𝐢𝐬𝐜𝐮𝐬𝐬 𝐭𝐡𝐞 𝐄𝐏𝐏 𝐂𝐮𝐫𝐫𝐢𝐜𝐮𝐥𝐮𝐦 𝐢𝐧 𝐭𝐡𝐞 𝐏𝐡𝐢𝐥𝐢𝐩𝐩𝐢𝐧𝐞𝐬:
- Understand the goals and objectives of the Edukasyong Pantahanan at Pangkabuhayan (EPP) curriculum, recognizing its importance in fostering practical life skills and values among students. Students will also be able to identify the key components and subjects covered, such as agriculture, home economics, industrial arts, and information and communication technology.
𝐄𝐱𝐩𝐥𝐚𝐢𝐧 𝐭𝐡𝐞 𝐍𝐚𝐭𝐮𝐫𝐞 𝐚𝐧𝐝 𝐒𝐜𝐨𝐩𝐞 𝐨𝐟 𝐚𝐧 𝐄𝐧𝐭𝐫𝐞𝐩𝐫𝐞𝐧𝐞𝐮𝐫:
-Define entrepreneurship, distinguishing it from general business activities by emphasizing its focus on innovation, risk-taking, and value creation. Students will describe the characteristics and traits of successful entrepreneurs, including their roles and responsibilities, and discuss the broader economic and social impacts of entrepreneurial activities on both local and global scales.
NIPER 2024 MEMORY BASED QUESTIONS.ANSWERS TO NIPER 2024 QUESTIONS.NIPER JEE 2...
NIPER JEE PYQ
NIPER JEE QUESTIONS
MOST FREQUENTLY ASK QUESTIONS
NIPER MEMORY BASED QUWSTIONS
Andreas Schleicher presents PISA 2022 Volume III - Creative Thinking - 18 Jun...
Andreas Schleicher, Director of Education and Skills at the OECD presents at the launch of PISA 2022 Volume III - Creative Minds, Creative Schools on 18 June 2024.
Level 3 NCEA - NZ: A Nation In the Making 1872 - 1900 SML.ppt
The History of NZ 1870-1900.
Making of a Nation.
From the NZ Wars to Liberals,
Richard Seddon, George Grey,
Social Laboratory, New Zealand,
Confiscations, Kotahitanga, Kingitanga, Parliament, Suffrage, Repudiation, Economic Change, Agriculture, Gold Mining, Timber, Flax, Sheep, Dairying,
Accounting for Restricted Grants When and How To Record Properly
In this webinar, member learned how to stay in compliance with generally accepted accounting principles (GAAP) for restricted grants.
How to Manage Reception Report in Odoo 17
A business may deal with both sales and purchases occasionally. They buy things from vendors and then sell them to their customers. Such dealings can be confusing at times. Because multiple clients may inquire about the same product at the same time, after purchasing those products, customers must be assigned to them. Odoo has a tool called Reception Report that can be used to complete this assignment. By enabling this, a reception report comes automatically after confirming a receipt, from which we can assign products to orders.
Temple of Asclepius in Thrace. Excavation results
The temple and the sanctuary around were dedicated to Asklepios Zmidrenus. This name has been known since 1875 when an inscription dedicated to him was discovered in Rome. The inscription is dated in 227 AD and was left by soldiers originating from the city of Philippopolis (modern Plovdiv).
CapTechTalks Webinar Slides June 2024 Donovan Wright.pptx
Slides from a Capitol Technology University webinar held June 20, 2024. The webinar featured Dr. Donovan Wright, presenting on the Department of Defense Digital Transformation.
THE SACRIFICE HOW PRO-PALESTINE PROTESTS STUDENTS ARE SACRIFICING TO CHANGE T...
The recent surge in pro-Palestine student activism has prompted significant responses from universities, ranging from negotiations and divestment commitments to increased transparency about investments in companies supporting the war on Gaza. This activism has led to the cessation of student encampments but also highlighted the substantial sacrifices made by students, including academic disruptions and personal risks. The primary drivers of these protests are poor university administration, lack of transparency, and inadequate communication between officials and students. This study examines the profound emotional, psychological, and professional impacts on students engaged in pro-Palestine protests, focusing on Generation Z's (Gen-Z) activism dynamics. This paper explores the significant sacrifices made by these students and even the professors supporting the pro-Palestine movement, with a focus on recent global movements. Through an in-depth analysis of printed and electronic media, the study examines the impacts of these sacrifices on the academic and personal lives of those involved. The paper highlights examples from various universities, demonstrating student activism's long-term and short-term effects, including disciplinary actions, social backlash, and career implications. The researchers also explore the broader implications of student sacrifices. The findings reveal that these sacrifices are driven by a profound commitment to justice and human rights, and are influenced by the increasing availability of information, peer interactions, and personal convictions. The study also discusses the broader implications of this activism, comparing it to historical precedents and assessing its potential to influence policy and public opinion. The emotional and psychological toll on student activists is significant, but their sense of purpose and community support mitigates some of these challenges. However, the researchers call for acknowledging the broader Impact of these sacrifices on the future global movement of FreePalestine.
Recently uploaded (20)
Geography as a Discipline Chapter 1 __ Class 11 Geography NCERT _ Class Notes...
Geography as a Discipline Chapter 1 __ Class 11 Geography NCERT _ Class Notes...
مصحف القراءات العشر أعد أحرف الخلاف سمير بسيوني.pdf
مصحف القراءات العشر أعد أحرف الخلاف سمير بسيوني.pdf
Philippine Edukasyong Pantahanan at Pangkabuhayan (EPP) Curriculum
Philippine Edukasyong Pantahanan at Pangkabuhayan (EPP) Curriculum
NIPER 2024 MEMORY BASED QUESTIONS.ANSWERS TO NIPER 2024 QUESTIONS.NIPER JEE 2...
NIPER 2024 MEMORY BASED QUESTIONS.ANSWERS TO NIPER 2024 QUESTIONS.NIPER JEE 2...
Andreas Schleicher presents PISA 2022 Volume III - Creative Thinking - 18 Jun...
Andreas Schleicher presents PISA 2022 Volume III - Creative Thinking - 18 Jun...
Level 3 NCEA - NZ: A Nation In the Making 1872 - 1900 SML.ppt
Level 3 NCEA - NZ: A Nation In the Making 1872 - 1900 SML.ppt
Accounting for Restricted Grants When and How To Record Properly
Accounting for Restricted Grants When and How To Record Properly
CapTechTalks Webinar Slides June 2024 Donovan Wright.pptx
CapTechTalks Webinar Slides June 2024 Donovan Wright.pptx
THE SACRIFICE HOW PRO-PALESTINE PROTESTS STUDENTS ARE SACRIFICING TO CHANGE T...
THE SACRIFICE HOW PRO-PALESTINE PROTESTS STUDENTS ARE SACRIFICING TO CHANGE T...
Neurofibroma stimulates salivary gland neoplasm - case report
- 1. P R E S E N T E D B Y D r . A J I N S C B PALATAL SOLITARY NEUROFIBROMA SIMULATES A SALIVARY GLAND NEOPLAM A CASE REPORT
- 2. INTRODUCTION Neurofibroma (NF) is a benign peripheral nerve sheath tumor sporadically occurring in the head and neck region. It could be solitary or multiple and intra or extra osseous
- 3. ETIOLOGY However, its definitive cause is still unknown It is derived from perineural cells, Schwann cells and fibroblasts within the myxoid matrix and varying amounts of mature collagen.
- 4. CLINICAL FEATURES It is usually slow growing,well- circumscribed and non-encapsulated in nature. It may affect any site in the oral cavity, the common ones being the tongue and buccal mucosa followed by lips and gingiva Intraosseous location has been described frequently; however extraosseous occurrence is rare
- 5. CASE REPORT This is a case report of a young man with extra- osseous solitary NF on the hard palate, which clinically mimicked a salivary gland neoplasm
- 6. CHIEF COMPLAINT A 23-year-old male reported to the dental college with chief complaint of a swelling on his palate since past two months, which was insidious in onset and gradually increased to present size The swelling was not associated with pain or discomfort to the patient.
- 7. Medical history : no medical history Dental history : no dental history Family history : no family history
- 8. INTRAORAL FEATURES On intraoralexamination, the swelling was present on posterior right side of the hard palate, not crossing the mid palatine raphe. It was oval in shape measuring approximately 3×1 cm, non-compressible, non-tender and fixed to underlying structures with normal overlying mucosa.
- 9. PROVISIONAL DIAGNOSIS Based on the clinical appearance and history, a provisional diagnosis of pleomorphic adenoma of the hard palate was made.
- 10. Under general anaesthesia,incision was given on most prominent part of the swelling. The tumor was excised completely along with normal tissue outline and sent for histopathological examination.
- 11. HISTOPATHOLOGICAL FEATURES Biopsied tissue under microscope showed fibrous capsule, abundant spindle cells proliferation and numerous salivary gland acini. At one end, tissue exhibited overlying stratified squamous epithelium, hyalinized areas and monotonous proliferation of spindle cells around salivary gland acini as well as sheets of these tumor cells spread out in the stroma. At other end, fibrous capsule was present adjacent to which minor salivary gland was seen.
- 12. UNDER HIGH MAGNIFICATION The histopathological picture on high power magnification revealed monomorphic proliferation of abundant spindle cells with benign slender oval nuclei and pointed ends. Few areas showed wavy nuclei intermingled with intertwining connective tissue fibrils
- 13. PAS STAINING PAS staining was performed and it came out to be negative
- 14. IMMUNOHISTOCHEMISTRY The spindle cells were positive for vimentin, CD34 and S100 while negative for SMA, β catenin and myogenin
- 15. DIFFERENTIAL DIAGNOSIS The closest histological differential diagnoses include solitary fibrous tumor, spindle cell lipoma, leiomyoma and myoepithelioma with spindle cell features
- 16. FINAL DIAGNOSIS Hence, it was finally diagnosed as neurofibroma.
- 17. TREATMENT Subsequently the patient was examined for any other signs of VRD. After no other systemic manifestation,it was finally concluded to be an extra- osseous solitary NF and on successive follow-ups, no recurrence has been reported.
- 18. DISCUSSION Therefore, in cases of spindle cell tumors, various origins like neural, myofibroblastic, muscle, fibroblastic, vascular, epithelial and odontogenic should be ruled out. If the patient is diagnosed with solitary NF he/she should be kept on regular follow up, as it could be the first manifestation of type I neurofibromatosis. Therefore, the ambiguity between salivary and neural etiology provided a diagnostic challenge, so clinical, histopathologic and immunohistochemical techniques were helpful in rendering an accurate diagnosis.
- 19. REFERENCES Ramdurg P, Puranik SR, Dantu R, Shivanand R. Solitary neurofibroma of the Soft palate: a rare entity. Indian J Otolaryngol Head Neck Sur Pollack RP. Neurofibroma of the palatal mucosa. A case report. J Periodontol Powell CA, Stanley CM, Bannister SR, McDonnell HT, Moritz AJ, Deas DE. Palatal neurofibroma associated with localized periodontitis. J Periodontol
- 20. THANK YOU