This document discusses principles of surgical approaches to central nervous system (CNS) lesions. It covers brain and spine lesions and various surgical techniques. For the brain, it describes common lesion types and goals of surgery. It then explains different surgical approaches like craniotomy, craniectomy, endoscopy, and stereotactic procedures. For the spine, it outlines common lesion locations and types of tumors. It also discusses posterior and anterior surgical approaches to access different spinal regions. The document provides examples of various patients who underwent these procedures.