IT infrastructure such as switches and servers is the traditional focus of network monitoring tools. Increasingly organisations are focusing on monitoring business critical applications sitting on top of this infrastructure. Altinity have deployed their Opsview software in a number enterprise environments to ensure availability of business critical applications and capture data for capacity planning. We will explain how we approach monitoring in these environment and what challenges we encounter. Opsview is an Open Source monitoring solution based on Nagios. Altinity are the commercial organsiation behind Opsview.