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To Get an Idea of What the
 Endocrine System Does:
Lets take a look at all the vital
organs of Endocrine System
Gland – A Gland is a group of cells that produce and
         secrete chemicals called hormones.

Hormones are transported into the blood stream to act
          on various parts of the body....

Hormones are responsible to help control normal body
                   processes.
Pineal Gland


• Located in the brain
• Makes a hormone called Melatonin
  (controls sleeping schedule)
Hypothalamus

• Located in the brain, above the pituitary gland
• Sends out numerous hormones
• Controls our nervous system (sleeping, eating, body
  temperature)
Pituitary Gland

• Called “Master
  Gland”
• Located in the
  bottom of the brain
• Creates different
  hormones that
  control different
  glands
• Two parts of the
  pituitary gland:
  anterior and posterior
• Controls growth, and
  development
Thyroid Gland
• Located in the neck
• Makes thyroid hormones, which regulate
  metabolism, and organ function
• Works with the hypothalamus and pituitary gland
Pancreas

• Located behind your stomach
• Maintains blood sugar levels
• Releases insulin, which help glucose move
Adrenal Gland
• Located near the lower back, above the kidneys

• Secretes numerous hormones that helps deal with
  stress, and physical development
Reproductive Glands
                (Gonads)

• Female: Ovaries        •   Male: Testes
• Creates estrogen and   •   Creates testosterone
  progesterone           •   Helps a boy develop
• Helps with babies      •   Deepens the voice, and
                             maintains muscle mass
I have focused my research on
        Pituitary Gland

     And Here it goes…..
Pituitary Gland

The pituitary gland
controls the
functions of many
of the other
endocrine glands.




It is about the
size of a pea !.
Location of the Pituitary
        Gland

This is the
pituitary gland!
Location of the pituitary and
hypothalamus

 The hypothalamus is
 located at the base of the
 brain in the posterior part .    Hypothalamus




                                             Pituitary
                                             stalk
                                 Anterior       Posterior
                                 pituitary      pituitary

 The pituitary is also
 located at the base
 of the brain
Location of the pituitary gland


 The pituitary
 gland itself               Hypothalamus

 consists of two
 main parts:
                                       Pituitary
                                       stalk
 • the anterior            Anterior       Posterior
                           pituitary      pituitary
 lobe


 • the posterior
 lobe
Posterior pituitary gland
Hormones
                                           The posterior pituitary secretes
                   Hypothalamus            2 important hormones :


                                             • Anti-diuretic hormone (ADH),


                                             • Oxytocin


                        Posterior pituitary

                                                     ADH          kidney

       Anterior
       Anterior
       pituitary
       pituitary


                          pituitary vein

                                                Oxytocin     breast and
                                                             uterus
What are the actions of the posterior pituitary
hormones?


  Anti-diuretic hormone (ADH)
                                      External
                                      stimulus e.g.
                                      low blood
                                      pressure
  • ADH secretion is stimulated by
  low blood pressure


  • ADH increases water
  reabsorption in the kidney and so                   Posterior
  modulates blood pressure                            pituitary


                                                          ADH
  • A deficiency in ADH causes
  diabetes.
Oxytocin
                                      External stimulus
                                      e.g. stretching of
• Oxytocin secretion is stimulated    cervix or
by stretching of the cervix during    suckling
birth and suckling of the baby at
the breast


• Oxytocin stimulates uterine
contractions during labour and the
milk ejection reflex after birth                           Posterior
                                                           pituitary


• A deficiency of oxytocin causes                          Oxytocin
a failure in normal delivery of the
child and difficulty with breast
feeding
Now let’s look at the anterior
      pituitary gland:
Anterior pituitary hormones - Growth Hormone



1. Growth Hormone
(GH) regulates growth
in the muscles and
bones.

                                           GH
Deficiency results in growth failure and
short structure. Too much GH in the
body can result in tumor in pituitary,
excessive sweating and thickness of
bones.
Anterior pituitary hormones - LH and FSH

2. Luteinising Hormone
(LH) and Follicle
Stimulating Hormone
(FSH) control both the
ovaries and testes

Diminished secretion of LH or FSH can
                                            LH   FSH
result in failure of fertility functions.
Typically in males as failure in
production of normal numbers of
sperm. In females, cessation of
reproductive cycles is commonly
observed. Elevated levels of these
hormones have normally no biological
effects in humans.
Anterior pituitary hormones - Prolactin

3. Prolactin (PRL) initiates
lactation and promotes the
growth of the mammary
glands, ovaries and testes
                                            PRL

Deficiency promotes inappropriate
lactation, lack of menses, infertility in
females, and impotency in males.
Anterior pituitary hormones - Thyroid-stimulating
                       hormone




4. Thyroid-stimulating
hormone (TSH)
regulates the thyroid
gland                                   TSH
4. Thyroid-stimulating
hormone (TSH) regulates
the thyroid gland

                                      TSH
The thyroid hormones
play an important role in
controlling control                              parathyroid's
carbohydrate and fat                            thyroid
metabolism, deficiency
                                Thyroid
results in increased body       hormones
weight.
                            Metabolism, heat production,
                                      growth.
Anterior pituitary hormones - Adrenocorticotrophic
                         hormone




5. Adrenocorticotropic
hormone (ACTH) controls
hormone secretion from the
adrenal cortex                                ACTH
5. Adrenocorticotropic hormone
(ACTH) controls hormone secretion
from the adrenal cortex




Cortisol controls the metabolism of              ACTH
carbohydrates, fats and proteins,
inflammatory and immune responses,
and responses to stress
                                                             adrenal
                                                             cortex
                                       Adrenal cortex hormones


                                    Metabolism, immune system, stress
                                       responses, testosterone and
                                                oestrogen
6. Melanocyte Stimulating Hormone
(MSH) stimulates melanocytes in the skin


Corticotrophs in the anterior
pituitary gland secrete MSH
                                            MSH

MSH acts on melanocytes in the
epidermis of the skin to stimulate the               melanocytes
secretion of melanin                                 in the skin

                                           Melanin
6. Melanocyte Stimulating Hormone (MSH)
stimulates melanocytes in the skin


Corticotrophs in the anterior pituitary
gland secrete MSH

                                                     MSH

MSH acts on melanocytes in the epidermis
of the skin to stimulate the secretion of
                                                              melanocytes
melanin                                                       in the skin


Melanin controls pigmentation in the                Melanin
skin



                                Skin pigmentation
Summary of hormones secreted by the anterior
pituitary gland

So the anterior pituitary secretes at least 7 important
hormones:
  Growth Hormone (GH) regulates growth in muscles and bones and opposes the
  action of insulin

  Prolactin initiates lactation and promotes the growth of the mammary glands,
  ovaries and testes

  Luteinising Hormone (LH) and Follicle Stimulating Hormone (FSH)
  control both the ovaries and the testes

  Thyroid Stimulating Hormone (TSH) regulates the thyroid gland

  Adrenocorticotropic Hormone (ACTH) controls hormone secretion from the
  adrenal cortex

  Melanocyte Stimulating Hormone (MSH) stimulates melanocytes in the
  skin
Hope my presentation was
informative and you enjoyed as
much as I enjoyed compiling it.




       Aaman Basra
         Grade : 5 A

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My final presentation on endocrine system [compatibility mode]

  • 1.
  • 2. To Get an Idea of What the Endocrine System Does:
  • 3. Lets take a look at all the vital organs of Endocrine System
  • 4. Gland – A Gland is a group of cells that produce and secrete chemicals called hormones. Hormones are transported into the blood stream to act on various parts of the body.... Hormones are responsible to help control normal body processes.
  • 5. Pineal Gland • Located in the brain • Makes a hormone called Melatonin (controls sleeping schedule)
  • 6. Hypothalamus • Located in the brain, above the pituitary gland • Sends out numerous hormones • Controls our nervous system (sleeping, eating, body temperature)
  • 7. Pituitary Gland • Called “Master Gland” • Located in the bottom of the brain • Creates different hormones that control different glands • Two parts of the pituitary gland: anterior and posterior • Controls growth, and development
  • 8. Thyroid Gland • Located in the neck • Makes thyroid hormones, which regulate metabolism, and organ function • Works with the hypothalamus and pituitary gland
  • 9. Pancreas • Located behind your stomach • Maintains blood sugar levels • Releases insulin, which help glucose move
  • 10. Adrenal Gland • Located near the lower back, above the kidneys • Secretes numerous hormones that helps deal with stress, and physical development
  • 11. Reproductive Glands (Gonads) • Female: Ovaries • Male: Testes • Creates estrogen and • Creates testosterone progesterone • Helps a boy develop • Helps with babies • Deepens the voice, and maintains muscle mass
  • 12. I have focused my research on Pituitary Gland And Here it goes…..
  • 13. Pituitary Gland The pituitary gland controls the functions of many of the other endocrine glands. It is about the size of a pea !.
  • 14. Location of the Pituitary Gland This is the pituitary gland!
  • 15. Location of the pituitary and hypothalamus The hypothalamus is located at the base of the brain in the posterior part . Hypothalamus Pituitary stalk Anterior Posterior pituitary pituitary The pituitary is also located at the base of the brain
  • 16. Location of the pituitary gland The pituitary gland itself Hypothalamus consists of two main parts: Pituitary stalk • the anterior Anterior Posterior pituitary pituitary lobe • the posterior lobe
  • 17. Posterior pituitary gland Hormones The posterior pituitary secretes Hypothalamus 2 important hormones : • Anti-diuretic hormone (ADH), • Oxytocin Posterior pituitary ADH kidney Anterior Anterior pituitary pituitary pituitary vein Oxytocin breast and uterus
  • 18. What are the actions of the posterior pituitary hormones? Anti-diuretic hormone (ADH) External stimulus e.g. low blood pressure • ADH secretion is stimulated by low blood pressure • ADH increases water reabsorption in the kidney and so Posterior modulates blood pressure pituitary ADH • A deficiency in ADH causes diabetes.
  • 19. Oxytocin External stimulus e.g. stretching of • Oxytocin secretion is stimulated cervix or by stretching of the cervix during suckling birth and suckling of the baby at the breast • Oxytocin stimulates uterine contractions during labour and the milk ejection reflex after birth Posterior pituitary • A deficiency of oxytocin causes Oxytocin a failure in normal delivery of the child and difficulty with breast feeding
  • 20. Now let’s look at the anterior pituitary gland:
  • 21. Anterior pituitary hormones - Growth Hormone 1. Growth Hormone (GH) regulates growth in the muscles and bones. GH Deficiency results in growth failure and short structure. Too much GH in the body can result in tumor in pituitary, excessive sweating and thickness of bones.
  • 22. Anterior pituitary hormones - LH and FSH 2. Luteinising Hormone (LH) and Follicle Stimulating Hormone (FSH) control both the ovaries and testes Diminished secretion of LH or FSH can LH FSH result in failure of fertility functions. Typically in males as failure in production of normal numbers of sperm. In females, cessation of reproductive cycles is commonly observed. Elevated levels of these hormones have normally no biological effects in humans.
  • 23. Anterior pituitary hormones - Prolactin 3. Prolactin (PRL) initiates lactation and promotes the growth of the mammary glands, ovaries and testes PRL Deficiency promotes inappropriate lactation, lack of menses, infertility in females, and impotency in males.
  • 24. Anterior pituitary hormones - Thyroid-stimulating hormone 4. Thyroid-stimulating hormone (TSH) regulates the thyroid gland TSH
  • 25. 4. Thyroid-stimulating hormone (TSH) regulates the thyroid gland TSH The thyroid hormones play an important role in controlling control parathyroid's carbohydrate and fat thyroid metabolism, deficiency Thyroid results in increased body hormones weight. Metabolism, heat production, growth.
  • 26. Anterior pituitary hormones - Adrenocorticotrophic hormone 5. Adrenocorticotropic hormone (ACTH) controls hormone secretion from the adrenal cortex ACTH
  • 27. 5. Adrenocorticotropic hormone (ACTH) controls hormone secretion from the adrenal cortex Cortisol controls the metabolism of ACTH carbohydrates, fats and proteins, inflammatory and immune responses, and responses to stress adrenal cortex Adrenal cortex hormones Metabolism, immune system, stress responses, testosterone and oestrogen
  • 28. 6. Melanocyte Stimulating Hormone (MSH) stimulates melanocytes in the skin Corticotrophs in the anterior pituitary gland secrete MSH MSH MSH acts on melanocytes in the epidermis of the skin to stimulate the melanocytes secretion of melanin in the skin Melanin
  • 29. 6. Melanocyte Stimulating Hormone (MSH) stimulates melanocytes in the skin Corticotrophs in the anterior pituitary gland secrete MSH MSH MSH acts on melanocytes in the epidermis of the skin to stimulate the secretion of melanocytes melanin in the skin Melanin controls pigmentation in the Melanin skin Skin pigmentation
  • 30. Summary of hormones secreted by the anterior pituitary gland So the anterior pituitary secretes at least 7 important hormones: Growth Hormone (GH) regulates growth in muscles and bones and opposes the action of insulin Prolactin initiates lactation and promotes the growth of the mammary glands, ovaries and testes Luteinising Hormone (LH) and Follicle Stimulating Hormone (FSH) control both the ovaries and the testes Thyroid Stimulating Hormone (TSH) regulates the thyroid gland Adrenocorticotropic Hormone (ACTH) controls hormone secretion from the adrenal cortex Melanocyte Stimulating Hormone (MSH) stimulates melanocytes in the skin
  • 31. Hope my presentation was informative and you enjoyed as much as I enjoyed compiling it. Aaman Basra Grade : 5 A