Acute supraglottitis/epiglottitis is a rapidly progressing infection of the epiglottis and surrounding structures that can completely obstruct the airway. It is most commonly caused by Hib in children and GAS, S. pneumoniae, or MRSA in adults. Children typically present within 24 hours with high fever, sore throat, and drooling, while adolescents and adults have a milder presentation of severe sore throat and dyspnea. Physical exam reveals respiratory distress, inspiratory stridor, and retractions. Diagnosis is often clinical but laryngoscopy may show a "cherry red" epiglottis and neck radiographs can reveal the "thumbprint sign". Treatment