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This document discusses the role of research universities in regional economies using examples like KU Leuven, Stanford University, MIT, and Cambridge University. It notes that these "third generation universities" actively collaborate with industry through activities like spinning off companies, conducting applied research, and managing technology transfer. KU Leuven's technology transfer office called LRD works to promote knowledge and technology transfer between the university and industry by assessing inventions, obtaining patents, finding industrial partners, and more. The presentation argues that research universities can significantly contribute to regional economic growth and the development of knowledge economy clusters and industries through these types of technology commercialization activities and partnerships.

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“The Role of Research Universities for the Regional Economy a case study The Leuven Model Dr Martin Hinoul Moscow, december 10th , 2013 Business Development Manager KU Leuven R&D
World’s GDP and R&D Budgets ! 500 Bi $ versus 360 Bi $ ? 1,74 tr $ 16,5 tr $ 18 tr $ 3 % R&D 500 BI dollar 2% R&D360 Bi dollar 6,4 tr $ 5 tr $ 1,5 tr $ 2 tr $ Source : The World Bank-Reshaping Economic Geography, Hinoul M.Hinoul
SIR* World Report 2012 INDICATORS • Output • International Collaboration • Normalized Impact • High Quality Publications • Specialization Index (Gini index) • Excellence Rate • 3290 Research Institutions (strong criteria) • more than 80% of the world scientific output (2006-2010) (Global Ranking KU Leuven 68 (universities 32) - European Ranking KU Leuven 5) *Scimago Institutions Rankings M.Hinoul
Barosso’s dream (or nightmare) for 2020  75% of the active population should be employed in 2020 –Today in 2013 it is only 66%- A long way to go.  3% of the European GDP should be spent on R&D .  Today it is only 1,9%  One percent extra means an extra of 180 Bi€  One percent means also an extra 700.000 engineers and scientists.  R&D fine but how good is the valorization of the European research?  20/20/20 in 2020: Reducing green house gas emissions with 20% (level 1990) Energy reduction minus 20% Alternative Energy plus 20% M.Hinoul
Economic growth and the Knowledge Economy Regions M.Hinoul
Globally there are more than 50 well developed knowledge economy regions M.Hinoul
Source : Harvard Business Review July-August2012 – p.26 M.Hinoul
M.Hinoul
“Third Generation Universities” Some examples Stanford University, Palo Alto Cambridge MIT KU Leuven
Massachusetts Institute of Technology - MIT  February • • • • 2009: 25.800 companies founded by MIT alumni 3.3 mi employees Annual sales : 2 trillion $ 17th largest economy in the world Estimated Number Of Companies Founded By “Foreign” MIT Alumni  Impact on ecosystem: • < 10% MIT students are from Ma state BUT: > 30% firms started in Ma by MIT Location Total United States 2,340 alumni > 50% firms started by foreign students are located in the US Europe 790 Latin America 495 Asia 342 • Source: Bankboston Report (Kauffman Foundation) Vannevar Bush M.Hinoul
Stanford University at the basis of Silicon Valley  Leland Stanford governor of California    1887 first stone of the university 1891 (March 22) opening – 559 students David Starr Jordan – first rector  Frederick Emmon Terman      Start setting up companies such as Hewlett Packard, Varian, etc. Build the first research parks First Venture Capital which became later the famous Sand Hill venture capital Road 27 Nobel Prizes, a lot of National Medals and other distinctions Silicon Valley – more than 8000 high tech companies – hundred thousands of new jobs M.Hinoul
Regional Knowledge Economy It all started with professor Fred Terman at the Stanford University in 1939
Silicon Valley today A State of Mind
Silicon Valley – A complex Network of Clusters Clean Technology Route 101 – Route 280 - State of mind Silicon Valley Joint Venture Network Stanford University – UCSF - Berkeley VC – Kleiner Perkins Caulfield…NASDAQ 2005 2000 Nano-electronics-Bio Silicon Internet – Google – e-Bay –YahooAmazon.com - Facebook Networks – Cisco - Juniper (Bosack,Lerner& Troiano -1984) Software -Oracle 1980 Computers – Apple Computer - Sun 1975 Semiconductors – Shockley –-Intel 1955 1939 Electronics – Hewlett Packard Varian Stanford – Fred Terman M.Hinoul
The Power of Silicon Valley Cies 2012 Rank Company Market Value Bn $ March 31 2012 2012 Sales – Bn $ Net Profit – Bn$ 164,7 42 416 2012 1 Apple 2 Hewlett-Packard 119 -12 46 3 Intel 53 11 108 4 Google 51 10 262 5 Cisco Systems 47 9 111 6 Oracle 37 10 152 7 eBay 14 3 70 8 Synnex 10,3 0,159 1,4 9 Gilead Sciences 10 2,6 75 10 Applied Materials 8,1 - 16 514 88 1258 Total *GDP Be 444 Bn $ GDP Netherland 743 Bn $ Source: Silicon Valley 150 The Mercury News – May 2013 M.Hinoul
The “Echoes” of Silicon Valley are Everywhere
Cambridge An Ancient yet Hi-Tech and Modern City 804 year old University
The Cambridge Phenomenon 50 years young  5,000 companies founded since 1960  1400 truly “HiTech”companies today. 2,500 Total Tech.  45,000 jobs  Ten $1 billion dollar companies  Two $10 billion dollar companies  Roads, airports, guided bus, rail transportation  Attracting up to 20% of European Early Stage VC
Key Components of the Entrepreneurial Eco-system Cambridge University MRC Laboratory of Molecular Biology Cambridge Interactive System Sinclair Radionics 1960 CCL CAD Centre Sinclair Research Ltd Barclays Bank 1970 Analysys Cambridge Science Park Olivetti Research Laboratory (acquired by AT&T in 1999) Seiko Epson Research Lab PA Technology 1980 CHASE Unilever Cambridge Centre for Molecular Informatics Cambridge Capital Group Cambridge Angels EPSON St. John Innovation Centre CUE, Biology in Business Cambridge Research and Innovation Ltd (CRIL) Cambridge Network 1990 CfEL (previously CEC) 3i Babraham Bioincubator Enterprise Link Scientific Generics The Technology Partnership TTP Hitachi BP Cambridge Institute of Laboratory The Wellcome Biotechnolog y Trust Sanger Cantab Pharmaceuticals GEIF Institute of Manufacturing 2000 Philip s Nickerson Biotech Laboratory Eicon Research Ltd Acorn Judge Business School Cambridge Toshiba Gateway Cambridge Research ET Capital Laboratory Glaxo Cambridge Enterprise Glaxo Institute of Applied Pharmacology ERBI Avlar Amadeus Capital Partners Library Granta Park House Cambridge Create Research Partners Park CMI Microsoft Research (previously Entropic Research) TTP Ventures
The hi-tech start-ups and Networks associated with the Cambridge University RealVNC Virtual Network Merged with Andy Hopper Level5Network Computing Globespan Andy Hopper Steve Pope Ubisense Andy Hopper Peter Warton Andy Hopper Cambridge Andy Hopper Andy Ward Broadband IPV (Telemedia Hermann Hauser Acquired by American Pete Acquired by AT &T Systems) Andy Hopper Microwave Virata(ATML) Steggles Adaptive Simon Elliott David Cleevely VBN online Splashpower Acquired by Western Multiplex Hermann Hauser Corp Broadband TerraPrise Amadeus Capital Partners Hermann Hauser Tensails nCipher Mike Muller Richard Green Alex van Someren Andy Hopper Acquired by Tudor Brown Acquired by Nicko van Someren Broadcom ARM Jamie Urquhart Lily Chang GE ANT Element 14 Icera Acquired by Richard Green Small Alex van Someren James Hay Olivetti Stan Boland Stan Boland Authur Chance World Nicko van Someren Simon Knowles Simon Knowles Dick Newell Cambridge Interactive Systems Part of DAKO DakoCytomation John Snyder Dick Newell, Tom Sancha Diagnostics Merged with Webtop Acorn Charles Lang Hermann Hauser, Chris Keightley Cytomation Inc Hermann IQ Bio Shape Data Peter Duffett-Smith Smartlogik CAD Hauser Netchannel Acquired by CPS Hermann Hauser Acquired by Dialog Hermann Hauser NTL Top Jack Lang Cambridge Jack Lang Electronic Share Jack Lang express University Information Olivetti Research Lab Muscat John Snyder Martin Porter Enterprise Accelerator John Snyder Cambridge Adam Twiss Zeus Semiconductor David Reeves Technology Gehan Amaratunga Pilgrim Beart Florin Udrea ActiveRF Laser-Scan Analysys R. O. Frisch David Cleevely Adam Twiss Bryan Amesbury Antenova Pilgrim Beart Richard Friend Plastic Logic 1986-1990 ART Polight Technologies Stephen Elliott Pavel Krecmer version (Sept 2005) – not to be used or copied without permission Copyright – Y.M.Myint - y.myint@jims.cam.ac.uk, Dr. Shailendra Vyakarnam s.vyakarnam@jims.cam.ac.uk David Cleevely Cambridge Hermann Hauser Network Alec Broers 1991-1995 Collin Ager Garraint Davies Innovia 1996-2000 Acquired by E* Trade Richard Friend Until 1985 Daniel Hall Saviso Group CDT Cambridge 3G David Cleevely M-Spatial 2001-2002 Adrian Cuthbert Jon Billing
And a similar Network for Biosciences Acquired by Becker Underwood Merlin Biosciences William Bains Chris Arakis Greg Winter John Caldwell Iain Cubitt Evans Changed its name Merged with Pestex Diversys Andy Amedis to MicroBio Group Xenova Cyclacel Richards RiboTargets pharmaceutic Group Ltd Microscience Vernalis al Merlin Ventures Simon Sturge Ark Therapeutics Chris Evans Chris Evans Iain Cubitt Martin Davies Acquired by Vectura Celsis Axis Genetcs Toad Greg Winter Chris Lowe Prometic ReNeuron Chris Evans Cerebrus BioRobotics Daivd Chiswell J. McCann Biosciences Biovex ChiroTech Chris Evans CAT Inc Chris Evans Cambridge Chris Evans Rapigene Celltech Alan Munro Sensors Chris Lowe Enviros Smart Enzymatix Cantab Merged by Chris Evans Chris Lowe Holograms Pharmaceuticals Celltech Chris Lowe Ken Jones Chiroscience MRC LMB Affinity chromatography Group Chris Evans Genzyme Chris Lowe 1960s Purely Daniel Roach Alan Goodman (UK) - AGC David Bailey LiDCO Proteins Alan Goodman 1985 1984 Philip Dean Terry O’Brien Alan De Novo Cambridge CeNes David Bailey AdproTech Alan Goodman Goodman University Alan Peter Lachmann CORE ATM Biotica Technology Goodman Until 1985 Alan Peter Leadlay Goodman Kudos Jim Staunton Daniel Roach Oxford Pharmaceuticals Alan Alan Bimedica . Mark Bodmer Stephen Jackson Hexagen 1986-1990 Goodman Acquired by Incyte Peptide Goodman Avlar Therapeutics Metris Lorantis BioVentures Alan Goodman Mark Bodmer Now Acambis Therapeutics 1991-1995 Daniel Roach Amura Paradigm Stephen Smith Salix Alan Therapeutics Steve Charnock-Jones pharmaceutical Holometrica Mark Carlton Goodman Astex Abcam Roger Millington Solexa Alan Sense Technology Jonathan Milner 1996-2000 Shankar Goodman Proteomics Tom Blundell David Cleevely Balasubramanian Jonathan Blackburn Jonathan Milner Chris Abell David Klenerman David Cleevely Harren Jhoti Paul Goldsmith Akubio Cambridge Theranostics MC Ivan Petyaev Daniolabs David Klenerman, Tony Minson 2001-2002
Leuven, a region for innovation & high-tech entrepreneurship
The Leuven Region Close to Brussels Leuven Region: 95.000 habitants Airport Brussels Leuven
An old young city
The Leuven Case Education Research Foundation KU Leuven Brewery Den Hoorn Stella AB Inbev Famous researchers • Mercator • Vesalius • Frisius • Ortelius Exploitation research KU Leuven R&D Transfer Office Stanford University (1891) Fred Terman-1939 Hewlett, Packard,Varian(s) IPTEC Price IMEC • 137 spin offs • 300 tech companies • 7000 researchers • 7000 high tech jobs • Research Parks • Incubators M.Hinoul
University Leuven IMEC Knowledge Centers 664 mi€ R&D, 6400 Researchers High Tech Industrie 300 Technology Cies, 135 spin offs Life Sciences Nanotechnology Mechatronics Cleantech Clusters Technology Platforms Haasrode Arenberg Leuven Noord Genk THOR Tienen FFH Research Parks Networks M.Hinoul
KU Leuven Research & Development Technology Transfer Office A Bridge between research and industry
K.U.Leuven Research & Development received the 2008 IPTEC Tech Transfer Award Nominated: •K.U.Leuven R&D (Winner 2008) •Columbia University (USA) •Imperial Innovations (UK) •MIT (USA) •Wisconsin Alumni Research Foundation (USA) Received the award : •2006 : Stanford University (USA) •2007 : Tsinghua University (China) © 2007 LRD
LRD: Mission “Promoting and supporting knowledge and technology transfer between university and industry” Researchers • Research collaboration • Spin-offs and regional development • IP protection and licenses Companies
What is LRD? • LRD consists of: o Central multidisciplinary staff • Supports researchers in knowledge and technology transfer o Research divisions • 1,422 researchers & 397 supporting • Embedded in university via matrix structure • Virtual organisations in which (groups of) researchers (from different faculties or departments) can group their applied research, commercialindustrial and exploitation activities.
Intellectual property • What do we do? o o o o o o o Creating awareness and transferring knowledge Assessing the feasibility, patentability and market potential of an invention Determining a protection strategy Drafting and filing a patent application Following up on patent procedures and costs Negotiating and drafting NDAs, MTAs and license agreements Finding industrial partners
LRD research divisions Faculties, departments, research groups: quality in research and educational activities LRD divisions/projects: Contract and budgetary autonomy and flexibility incentives
Organisation Management (2) Research collaboration (17) • advice • contract R&D • projects with government support (IWT, EC, etc.) Intellectual property rights (12) • intellectual property rights • licensing Spin-off & innovation (9) • spin-off creation & growth • networks & regional development • KU Leuven Association Finance, HR & logistics (39) • financial administration • HRM administration • Close interaction and collaboration between different units • Regional and international networking
Activities • • • • • Research collaboration Protection and exploitation of intellectual property Spin-off creation & innovation Support of regional development Stimulation of entrepreneurship through network initiatives
Examples of technology transfer
Research collaboration • Oldest activity of LRD • Performing research & services for companies or governments • What do we do? o o o o o o o Creating awareness and transferring knowledge Providing advice Negotiating contracts Following up on contracts Managing research files financially Offering administrative support Preparing legal documents
Contract Research thousands € 160.000 160.000 € 140.000 144.802 126.807 € 120.000 121.653 € 100.000 97.844 87.908 € 80.000 70.193 € 60.000 54.332 € 40.000 € 20.000 €0 2004 2005 2006 2007 2008 2009 2010 2011
Intellectual property • Internal specialised office: protection and exploitation of intellectual property rights • Network of formal collaborations with different European patent attorneys • Patent Fund: selective support of research groups to help them cover their initial costs and expenses related to patenting needs
Intellectual property • 156 patent applications in 2011 o o 496 active patent families 49 PCTs In numbers 2011 Reported findings 154 Priority submissions 156 New patents 33 • 60 million euro license-income (71 million in 2012) • Attributed patent is often the basis for setting up a spin-off company
Spin-offs & innovation • What do we do? o o o o o o o o o Developing business plans Validating business models and the market Offering legal support Putting together a competent team Finding investors Finding infrastructure Managing growth of spin-offs Promoting valorisation and entrepreneurship Stimulating regional development, networks and clusters
Definition of a Technology Cluster Network relatedCies (VC, Seed, IP, Legal..) Mixed Innovative Cies Knowledge Centers Attraction Innovative Cies Creation Innovative Cies M.Hinoul
Mechatronica Kenniscentra Stas Ora Machines Centers of excellence ACE Electronics WTCM Optidrive Air Beraing Prec. Techn. Barco Aarschot Partec Eng Alnaco B.E.S.T. Materialise Electrical & Mech. Design DV Consulting IPCOS K.U.Leuven Dept. Mechanics Researh groups Metris Somatech Krypton Dynamotor Decoster Luyten Automation KULeuven SST Food Mach Atos Engineering Pure innovatieve bedrijven Camco Techn Flexlink Systems PEC EME K.U.Leuven Dept of Metall. & Mater. Eng Lab Agric Mach & Proc Entecom Systems Tecmate Intl. D2S International M&M Corporation Data Analys Products CSI Scala Consultants Mixed innovatieve bedrijven Donaldson LMS South Lancs Belgium Affilips Robert Bosch
Life Science Cluster Kenniscentra E.S.R.I. Deckers Div Dermat Centers of excellence Biotest Seralco Benelux Thrombogenics Tigenix Norgine IDT(RNA-TEC) Dakocytomation BioTie Therapies Corp. Univ hospitals K.U.Leuven Rega Institute CEHA Algonomics PatientWeb Medvision Benelux Puur innovatieve bedrijven Gemengd innovatieve bedrijven M-Elect M4S Materialise K.U.Leuven L-MTC Autocyte Europe Neurogenetics @Medical Techn. MXS VIB VIGOUR Custom8 Fugeia Malaise&co Terumo Europe Cochlear Lab of Exp. Genetics & Transgenese QMedit IVIA ReMynd Medicim CMPG Centocor Diatos Onco Methylome Regenesys New Standard Eng. Formac Pharmaceuticals VWR International Ortec Conti BPC
A Top Technology Region
Much more than the 3 % Lisbon target
HIGH TECH SYSTEMS & MATERIALEN Specialisatie en pieken: Selectie en typologie belangrijkste actoren TTR Nederland Nederlandse Vereniging voor Precisietechnologie Vereniging van de Nederlandse Chemische Industrie DSP Valley Sirris DAF nv Graco Siemens VDO Kenniscentra en centers of excellence Bosch Packaging FMTC (mechatronica) Vista nv Philips Chemelot Alro Holdings Ford Werke Bosch Hydraulic LAG Trailers Borealis Polymers Akzo Nobel Pure innovatieve bedrijven Netherlands Aerospace Group (NAG) ATC Eindhoven Mixed innovatieve bedrijven Océ Stork food systems en printing Campus Eindhoven Cerobear Verband der Chemischen industrie (VCI) KUL KUleuven UImec Hasselt Philips (licht)/ Philips Onderzoeksinstituut Trützschler FEV Motorentechnik Cluster Chemie/ Kunststoffe Mitteldeutschland INTRA e.V. * Internationaal netwerk: Automotive.net Tessenderlo chemie Forschungszentrum Jülich RWTH Hochschule Aachen Niederrhein Continental Schumag AG Spaas Kaarsen Prüfcentrum Siemens transportation Systems Agoria Heraeus Electro-Nite International Flanders Drive Oerlikon Textile Scheidt & Bachmann 3M Netwerken* DOW Belgium U Luik U Hasselt U Fraunhofer Institut Luik Siempelkamp FLAMAC (materialen onderzoek) Epiq Imec Philips DSM ASML Nederlandse vereniging voor rubber en kunststoffen Campus Geleen Nedcar Vanderlande Industries TTR België Walonie Espace Pierberg Voith Paper AUNDE Verband der Elektrotechnik (VDE) Munters Euroform CAR e.V. Verbundinitiative Automobil Nordrhein-Westfalen (VIA NRW) TTR Duitsland 49
K.U.Leuven Spin offs 100 90 80 70 Gemma Frisius-Seed Capital 2x 12,5 m€ 60 50 40 30 20 10 0 1980 1982 1984 1986 1988 1990 1992 1994 1996 1998 2000 2002 2004 2006 2008 2010 2012
Spillovers and multipliers • Spin-offs between 2006 - 2010: – K.U.Leuven direct investments: 4,7 M€ – Gemma Frisius Fund investments: 12 M€ – Other third party investments: 476 M€
Perennial topics Investment in spin-offs 2005 - 2012 700 000 000 631 426 634 Euro 600 000 000 500 000 000 400 000 000 300 000 000 200 000 000 100 000 000 7 453 606 14 591 843 KU Leuven GFF 0 derden
 Seed Capital – Venture Capital – 500 million € Risicokapitaal Arr. Leuven (2002) : 200 miljoen euro Servifund 12% Gemma Frisius Fonds 1 7% Stonefund 19% Beluga 12% Softw are Holding & Finance 8% Gemma Frisius Fonds 2 7% IMEC Incubatiefonds 3% Capricorn Venture Partners 12% Quest Management 20%
Spillovers and multipliers • Patent portfolios: – K.U.Leuven R&D, 454 active patent families of which 90% economically exploited – Multiplier effects of patent portfolios of spin-off companies  sectoral multipliers of 3 to 4
Examples in Life Sciences KU Leuven
Spin-off companies: some examples • Engineering • Micro-electronics & ICT
Spin-off companies: examples • Consultancy • Biomedical
Incubation & seed financing • Gemma Frisius Fund KU Leuven (GFF) o o Seed capital for spin-off companies GFF founded in 1997 & GFF II in 2002 • o At the end of 2009 GFF and GFF II merged into one single fund Partners: • • o KU Leuven (20% of capital) Two banks: KBC Private Equity (40%) and BNP Paribas Fortis Private Equity (40%) Combination between: • • o o Knowledge and technology transfer expertise (university) Financial expertise (financial partners) Not restricted to one technology domain 25 million euro invested in 38 spin-off companies
Regional and interregional development • Partners: o o o o o o o o City of Leuven Province of Flemish Brabant Vinnof CREA - European Commission KBC Private Equity BNP Paribas Fortis Private Equity imec VIB • ELAt: Eindhoven - Leuven - Aachen triangle o o Cross-border and interregional network Stimulation of knowledge economy • HAE : Health Axis Europe (Heidelberg, Leuven, Cambridge)
Networks • Stimulating knowledge exchange and partnering with other high-tech businesses (both SMEs and large companies) and innovation actors • Horizontal networks: o o Leuven.Inc Flanders Smart Hub
Networks • Vertical networks: o o DSP Valley LSEC • Thematic centres: o o o o o o o CD3 L-MRC L-MTC LICT PharmAbs NERF LFoRCe
Science parks, business centres & incubators • • • • • • • • Arenberg Science Park Haasrode Science Park Leuven Noord Science Park Waterschei - Genk Science Park Tienen Science Park Ubicenter Remy Campus Leuven Business Centre
Science parks, business centres & incubators • • • • Leuven Bio-Incubators Tienen Biogenerator KU Leuven Innovation & Incubation Centre (I&I) Kortrijk Innovation & Incubation Centre (IICK)
Multilevel interaction KU LEUVEN LRD Financial world Science GFF Parks Leuven.Inc Industry Region
12 Lessons from Leuven 1. Basis is a critical mass of high quality research 2. Create an appropriate entrepreneurial climate in a university context 3. Create a legal framework with respect to exploitation of academic research 4. Clear incentives and policies to encourage research groups and departments to actively seek knowledge transfer opportunities 5. Create a professional Interface Unit – An Integrated approach on research valorisation: multidisciplinary team & “high value” services 6. Create a Seed Capital and/or Venture Capital Fund
12 Lessons from Leuven 7. Foster spin-offs from your university research 8. Clear ownership of Intellectual Property 9. Improving awareness among federal, regional and local shareholders 10. Supporting a forum for business, academia, government and supporting organisations to build partnerships by sharing new ideas and best practices. Importance of the networks. 11. Focus on Focus and Enthusiasm 12. Quality of life
Success factors • A critical mass of high quality research • Multidisciplinary team & high value support • Clear incentives to encourage researchers and research groups • Favourable entrepreneurial climate within the university • Legal context in Flanders • Instruments and networks that further professionalise technology transfer support
Towards an Entrepreneurial Society    “The rise of the entrepreneur is not just about economics. It reflects profound changes from individual careers to the social contract. It signals the birth of an entrepreneurial society” -The EconomistMarch 14, 2009
The Value Chain is the barometer 1. Knowledge Centers 2. Entrepreneurs 3. Role Models 4. Money 5. Capital Markets 6. Infrastructure 7. Cluster Policy 8. International Companies 9. Networks 10. Government 11. Quality of Life Source : Hinoul, Gibbons, Saxenian
What makes a region attractive for talent?  Location – such as Silicon Valley, California – Sophia Antipolis, Mediteranée – Heidelberg Old University  Universities or Research Centers - Magnets for talent See Jiao Tong University League e.g. Stanford, Harvard, Princeton, IMEC Leuven, LETI Grenoble, CERN Geneva.  Presence of top Succesful Companies Microsoft, Intel, Google, ASML, LMS…  Presence of Strong Individuals – Role Models Bill Gates, Steve Jobs, Larry Page and even Nobel price winners.  Presence of Successful Clusters San Diego Biotech-Golden Triangle – North Carolina Research triangle  Fiscal System – Salaries, tax incentives, research budgets  Quality of Life – Leisure, Housing, Medical care, International schools, culture… Source: M. Hinoul – 7th Annual Conference – Technopolicy Network – Heidelberg 2010
Towards a new Form of Culture All things are possible attitude Risk Taking We have not enough spin-offs who fail Co-competition Stock options Based on Meritocracy Serial Entrepreneurs Time for the next big thing CULTURE Cross-pollination Inflection Point (Andy Grove) Cross-investments State of mind Networking Jumping on the Next Curve (Oracle) Failure Badge of merit Source : M. Hinoul ±
Flemish Entrepreneurs The old generation Leo Leander Bekaert Lieven Gevaert Leo H. Baekeland 75
Flemish Visionaries Gaston Geens John Cordier Paul Janssen Roger Van Overstraeten Marc Van Montagu Walter Fiers 76
Leuven Entrepreneurs A new generation . A.OOSTERLINCK J. DEJAEGER D. COLLEN P. STOFFELS S. BIJNENS U. VAN DEURZEN J. CALLEWAERT B. VAN COPPENOLLE F. VAN CRAEN T. DE PROFT
Speech recognition Data screening Micro electronics Cloud computing Components Interplanetary Space Flights Ground Navigation Suborbital Space flights Small satellites Platform & pay load Nuclear Medicine Medical devices Drug Delivery Bio Informatics Stemcells Interdisciplinary Research Clusters and Research Directions Confidential-M.Hinoul
Clusters and Interdisciplinary Research at Skolkovo Director TTO  Research Collaboration  IPR(Royalties,Licencing)  Spin offs – Start ups  Finance (Seed, VC, IPO) 5 Research Programs (Clusters) Research Centers Interdisciplinary approach A close interaction between different research divisions Technopark (a state of the art infrastructure) Russian & International Cies Russian & International Research Centers
Dual Incentive Mechanism Russian & International Universities Russian & International Cies SIST Technopark  Striving for scientific excellence  Gearing this excellence towards application and technological innovation Creation of the Knowledge Economy Region Skolkovo
Contact KU Leuven Research & Development (LRD) Waaistraat 6 – box 5105 3000 Leuven, Belgium Tel.+32 16 32 65 00 lrd@kuleuven.be lrd.kuleuven.be

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Moscow 10 december 2013

  • 1.
    “The Role ofResearch Universities for the Regional Economy a case study The Leuven Model Dr Martin Hinoul Moscow, december 10th , 2013 Business Development Manager KU Leuven R&D
  • 2.
    World’s GDP andR&D Budgets ! 500 Bi $ versus 360 Bi $ ? 1,74 tr $ 16,5 tr $ 18 tr $ 3 % R&D 500 BI dollar 2% R&D360 Bi dollar 6,4 tr $ 5 tr $ 1,5 tr $ 2 tr $ Source : The World Bank-Reshaping Economic Geography, Hinoul M.Hinoul
  • 3.
    SIR* World Report2012 INDICATORS • Output • International Collaboration • Normalized Impact • High Quality Publications • Specialization Index (Gini index) • Excellence Rate • 3290 Research Institutions (strong criteria) • more than 80% of the world scientific output (2006-2010) (Global Ranking KU Leuven 68 (universities 32) - European Ranking KU Leuven 5) *Scimago Institutions Rankings M.Hinoul
  • 4.
    Barosso’s dream (ornightmare) for 2020  75% of the active population should be employed in 2020 –Today in 2013 it is only 66%- A long way to go.  3% of the European GDP should be spent on R&D .  Today it is only 1,9%  One percent extra means an extra of 180 Bi€  One percent means also an extra 700.000 engineers and scientists.  R&D fine but how good is the valorization of the European research?  20/20/20 in 2020: Reducing green house gas emissions with 20% (level 1990) Energy reduction minus 20% Alternative Energy plus 20% M.Hinoul
  • 5.
    Economic growth andthe Knowledge Economy Regions M.Hinoul
  • 6.
    Globally there aremore than 50 well developed knowledge economy regions M.Hinoul
  • 7.
    Source : HarvardBusiness Review July-August2012 – p.26 M.Hinoul
  • 8.
  • 9.
    “Third Generation Universities” Someexamples Stanford University, Palo Alto Cambridge MIT KU Leuven
  • 10.
    Massachusetts Institute of Technology- MIT  February • • • • 2009: 25.800 companies founded by MIT alumni 3.3 mi employees Annual sales : 2 trillion $ 17th largest economy in the world Estimated Number Of Companies Founded By “Foreign” MIT Alumni  Impact on ecosystem: • < 10% MIT students are from Ma state BUT: > 30% firms started in Ma by MIT Location Total United States 2,340 alumni > 50% firms started by foreign students are located in the US Europe 790 Latin America 495 Asia 342 • Source: Bankboston Report (Kauffman Foundation) Vannevar Bush M.Hinoul
  • 11.
    Stanford University atthe basis of Silicon Valley  Leland Stanford governor of California    1887 first stone of the university 1891 (March 22) opening – 559 students David Starr Jordan – first rector  Frederick Emmon Terman      Start setting up companies such as Hewlett Packard, Varian, etc. Build the first research parks First Venture Capital which became later the famous Sand Hill venture capital Road 27 Nobel Prizes, a lot of National Medals and other distinctions Silicon Valley – more than 8000 high tech companies – hundred thousands of new jobs M.Hinoul
  • 12.
    Regional Knowledge Economy Itall started with professor Fred Terman at the Stanford University in 1939
  • 13.
  • 14.
    Silicon Valley –A complex Network of Clusters Clean Technology Route 101 – Route 280 - State of mind Silicon Valley Joint Venture Network Stanford University – UCSF - Berkeley VC – Kleiner Perkins Caulfield…NASDAQ 2005 2000 Nano-electronics-Bio Silicon Internet – Google – e-Bay –YahooAmazon.com - Facebook Networks – Cisco - Juniper (Bosack,Lerner& Troiano -1984) Software -Oracle 1980 Computers – Apple Computer - Sun 1975 Semiconductors – Shockley –-Intel 1955 1939 Electronics – Hewlett Packard Varian Stanford – Fred Terman M.Hinoul
  • 15.
    The Power of SiliconValley Cies 2012 Rank Company Market Value Bn $ March 31 2012 2012 Sales – Bn $ Net Profit – Bn$ 164,7 42 416 2012 1 Apple 2 Hewlett-Packard 119 -12 46 3 Intel 53 11 108 4 Google 51 10 262 5 Cisco Systems 47 9 111 6 Oracle 37 10 152 7 eBay 14 3 70 8 Synnex 10,3 0,159 1,4 9 Gilead Sciences 10 2,6 75 10 Applied Materials 8,1 - 16 514 88 1258 Total *GDP Be 444 Bn $ GDP Netherland 743 Bn $ Source: Silicon Valley 150 The Mercury News – May 2013 M.Hinoul
  • 19.
    The “Echoes” ofSilicon Valley are Everywhere
  • 20.
    Cambridge An Ancient yetHi-Tech and Modern City 804 year old University
  • 21.
    The Cambridge Phenomenon 50years young  5,000 companies founded since 1960  1400 truly “HiTech”companies today. 2,500 Total Tech.  45,000 jobs  Ten $1 billion dollar companies  Two $10 billion dollar companies  Roads, airports, guided bus, rail transportation  Attracting up to 20% of European Early Stage VC
  • 22.
    Key Components ofthe Entrepreneurial Eco-system Cambridge University MRC Laboratory of Molecular Biology Cambridge Interactive System Sinclair Radionics 1960 CCL CAD Centre Sinclair Research Ltd Barclays Bank 1970 Analysys Cambridge Science Park Olivetti Research Laboratory (acquired by AT&T in 1999) Seiko Epson Research Lab PA Technology 1980 CHASE Unilever Cambridge Centre for Molecular Informatics Cambridge Capital Group Cambridge Angels EPSON St. John Innovation Centre CUE, Biology in Business Cambridge Research and Innovation Ltd (CRIL) Cambridge Network 1990 CfEL (previously CEC) 3i Babraham Bioincubator Enterprise Link Scientific Generics The Technology Partnership TTP Hitachi BP Cambridge Institute of Laboratory The Wellcome Biotechnolog y Trust Sanger Cantab Pharmaceuticals GEIF Institute of Manufacturing 2000 Philip s Nickerson Biotech Laboratory Eicon Research Ltd Acorn Judge Business School Cambridge Toshiba Gateway Cambridge Research ET Capital Laboratory Glaxo Cambridge Enterprise Glaxo Institute of Applied Pharmacology ERBI Avlar Amadeus Capital Partners Library Granta Park House Cambridge Create Research Partners Park CMI Microsoft Research (previously Entropic Research) TTP Ventures
  • 23.
    The hi-tech start-upsand Networks associated with the Cambridge University RealVNC Virtual Network Merged with Andy Hopper Level5Network Computing Globespan Andy Hopper Steve Pope Ubisense Andy Hopper Peter Warton Andy Hopper Cambridge Andy Hopper Andy Ward Broadband IPV (Telemedia Hermann Hauser Acquired by American Pete Acquired by AT &T Systems) Andy Hopper Microwave Virata(ATML) Steggles Adaptive Simon Elliott David Cleevely VBN online Splashpower Acquired by Western Multiplex Hermann Hauser Corp Broadband TerraPrise Amadeus Capital Partners Hermann Hauser Tensails nCipher Mike Muller Richard Green Alex van Someren Andy Hopper Acquired by Tudor Brown Acquired by Nicko van Someren Broadcom ARM Jamie Urquhart Lily Chang GE ANT Element 14 Icera Acquired by Richard Green Small Alex van Someren James Hay Olivetti Stan Boland Stan Boland Authur Chance World Nicko van Someren Simon Knowles Simon Knowles Dick Newell Cambridge Interactive Systems Part of DAKO DakoCytomation John Snyder Dick Newell, Tom Sancha Diagnostics Merged with Webtop Acorn Charles Lang Hermann Hauser, Chris Keightley Cytomation Inc Hermann IQ Bio Shape Data Peter Duffett-Smith Smartlogik CAD Hauser Netchannel Acquired by CPS Hermann Hauser Acquired by Dialog Hermann Hauser NTL Top Jack Lang Cambridge Jack Lang Electronic Share Jack Lang express University Information Olivetti Research Lab Muscat John Snyder Martin Porter Enterprise Accelerator John Snyder Cambridge Adam Twiss Zeus Semiconductor David Reeves Technology Gehan Amaratunga Pilgrim Beart Florin Udrea ActiveRF Laser-Scan Analysys R. O. Frisch David Cleevely Adam Twiss Bryan Amesbury Antenova Pilgrim Beart Richard Friend Plastic Logic 1986-1990 ART Polight Technologies Stephen Elliott Pavel Krecmer version (Sept 2005) – not to be used or copied without permission Copyright – Y.M.Myint - y.myint@jims.cam.ac.uk, Dr. Shailendra Vyakarnam s.vyakarnam@jims.cam.ac.uk David Cleevely Cambridge Hermann Hauser Network Alec Broers 1991-1995 Collin Ager Garraint Davies Innovia 1996-2000 Acquired by E* Trade Richard Friend Until 1985 Daniel Hall Saviso Group CDT Cambridge 3G David Cleevely M-Spatial 2001-2002 Adrian Cuthbert Jon Billing
  • 24.
    And a similarNetwork for Biosciences Acquired by Becker Underwood Merlin Biosciences William Bains Chris Arakis Greg Winter John Caldwell Iain Cubitt Evans Changed its name Merged with Pestex Diversys Andy Amedis to MicroBio Group Xenova Cyclacel Richards RiboTargets pharmaceutic Group Ltd Microscience Vernalis al Merlin Ventures Simon Sturge Ark Therapeutics Chris Evans Chris Evans Iain Cubitt Martin Davies Acquired by Vectura Celsis Axis Genetcs Toad Greg Winter Chris Lowe Prometic ReNeuron Chris Evans Cerebrus BioRobotics Daivd Chiswell J. McCann Biosciences Biovex ChiroTech Chris Evans CAT Inc Chris Evans Cambridge Chris Evans Rapigene Celltech Alan Munro Sensors Chris Lowe Enviros Smart Enzymatix Cantab Merged by Chris Evans Chris Lowe Holograms Pharmaceuticals Celltech Chris Lowe Ken Jones Chiroscience MRC LMB Affinity chromatography Group Chris Evans Genzyme Chris Lowe 1960s Purely Daniel Roach Alan Goodman (UK) - AGC David Bailey LiDCO Proteins Alan Goodman 1985 1984 Philip Dean Terry O’Brien Alan De Novo Cambridge CeNes David Bailey AdproTech Alan Goodman Goodman University Alan Peter Lachmann CORE ATM Biotica Technology Goodman Until 1985 Alan Peter Leadlay Goodman Kudos Jim Staunton Daniel Roach Oxford Pharmaceuticals Alan Alan Bimedica . Mark Bodmer Stephen Jackson Hexagen 1986-1990 Goodman Acquired by Incyte Peptide Goodman Avlar Therapeutics Metris Lorantis BioVentures Alan Goodman Mark Bodmer Now Acambis Therapeutics 1991-1995 Daniel Roach Amura Paradigm Stephen Smith Salix Alan Therapeutics Steve Charnock-Jones pharmaceutical Holometrica Mark Carlton Goodman Astex Abcam Roger Millington Solexa Alan Sense Technology Jonathan Milner 1996-2000 Shankar Goodman Proteomics Tom Blundell David Cleevely Balasubramanian Jonathan Blackburn Jonathan Milner Chris Abell David Klenerman David Cleevely Harren Jhoti Paul Goldsmith Akubio Cambridge Theranostics MC Ivan Petyaev Daniolabs David Klenerman, Tony Minson 2001-2002
  • 25.
    Leuven, a regionfor innovation & high-tech entrepreneurship
  • 26.
    The Leuven Region Closeto Brussels Leuven Region: 95.000 habitants Airport Brussels Leuven
  • 27.
  • 28.
    The Leuven Case Education Research Foundation KULeuven Brewery Den Hoorn Stella AB Inbev Famous researchers • Mercator • Vesalius • Frisius • Ortelius Exploitation research KU Leuven R&D Transfer Office Stanford University (1891) Fred Terman-1939 Hewlett, Packard,Varian(s) IPTEC Price IMEC • 137 spin offs • 300 tech companies • 7000 researchers • 7000 high tech jobs • Research Parks • Incubators M.Hinoul
  • 29.
    University Leuven IMEC Knowledge Centers 664mi€ R&D, 6400 Researchers High Tech Industrie 300 Technology Cies, 135 spin offs Life Sciences Nanotechnology Mechatronics Cleantech Clusters Technology Platforms Haasrode Arenberg Leuven Noord Genk THOR Tienen FFH Research Parks Networks M.Hinoul
  • 30.
    KU Leuven Research& Development Technology Transfer Office A Bridge between research and industry
  • 31.
    K.U.Leuven Research &Development received the 2008 IPTEC Tech Transfer Award Nominated: •K.U.Leuven R&D (Winner 2008) •Columbia University (USA) •Imperial Innovations (UK) •MIT (USA) •Wisconsin Alumni Research Foundation (USA) Received the award : •2006 : Stanford University (USA) •2007 : Tsinghua University (China) © 2007 LRD
  • 32.
    LRD: Mission “Promoting andsupporting knowledge and technology transfer between university and industry” Researchers • Research collaboration • Spin-offs and regional development • IP protection and licenses Companies
  • 33.
    What is LRD? •LRD consists of: o Central multidisciplinary staff • Supports researchers in knowledge and technology transfer o Research divisions • 1,422 researchers & 397 supporting • Embedded in university via matrix structure • Virtual organisations in which (groups of) researchers (from different faculties or departments) can group their applied research, commercialindustrial and exploitation activities.
  • 34.
    Intellectual property • Whatdo we do? o o o o o o o Creating awareness and transferring knowledge Assessing the feasibility, patentability and market potential of an invention Determining a protection strategy Drafting and filing a patent application Following up on patent procedures and costs Negotiating and drafting NDAs, MTAs and license agreements Finding industrial partners
  • 35.
    LRD research divisions Faculties,departments, research groups: quality in research and educational activities LRD divisions/projects: Contract and budgetary autonomy and flexibility incentives
  • 36.
    Organisation Management (2) Research collaboration (17) • advice •contract R&D • projects with government support (IWT, EC, etc.) Intellectual property rights (12) • intellectual property rights • licensing Spin-off & innovation (9) • spin-off creation & growth • networks & regional development • KU Leuven Association Finance, HR & logistics (39) • financial administration • HRM administration • Close interaction and collaboration between different units • Regional and international networking
  • 37.
    Activities • • • • • Research collaboration Protection andexploitation of intellectual property Spin-off creation & innovation Support of regional development Stimulation of entrepreneurship through network initiatives
  • 38.
  • 39.
    Research collaboration • Oldestactivity of LRD • Performing research & services for companies or governments • What do we do? o o o o o o o Creating awareness and transferring knowledge Providing advice Negotiating contracts Following up on contracts Managing research files financially Offering administrative support Preparing legal documents
  • 40.
    Contract Research thousands € 160.000 160.000 €140.000 144.802 126.807 € 120.000 121.653 € 100.000 97.844 87.908 € 80.000 70.193 € 60.000 54.332 € 40.000 € 20.000 €0 2004 2005 2006 2007 2008 2009 2010 2011
  • 41.
    Intellectual property • Internalspecialised office: protection and exploitation of intellectual property rights • Network of formal collaborations with different European patent attorneys • Patent Fund: selective support of research groups to help them cover their initial costs and expenses related to patenting needs
  • 42.
    Intellectual property • 156patent applications in 2011 o o 496 active patent families 49 PCTs In numbers 2011 Reported findings 154 Priority submissions 156 New patents 33 • 60 million euro license-income (71 million in 2012) • Attributed patent is often the basis for setting up a spin-off company
  • 43.
    Spin-offs & innovation •What do we do? o o o o o o o o o Developing business plans Validating business models and the market Offering legal support Putting together a competent team Finding investors Finding infrastructure Managing growth of spin-offs Promoting valorisation and entrepreneurship Stimulating regional development, networks and clusters
  • 44.
    Definition of aTechnology Cluster Network relatedCies (VC, Seed, IP, Legal..) Mixed Innovative Cies Knowledge Centers Attraction Innovative Cies Creation Innovative Cies M.Hinoul
  • 45.
    Mechatronica Kenniscentra Stas Ora Machines Centers of excellence ACEElectronics WTCM Optidrive Air Beraing Prec. Techn. Barco Aarschot Partec Eng Alnaco B.E.S.T. Materialise Electrical & Mech. Design DV Consulting IPCOS K.U.Leuven Dept. Mechanics Researh groups Metris Somatech Krypton Dynamotor Decoster Luyten Automation KULeuven SST Food Mach Atos Engineering Pure innovatieve bedrijven Camco Techn Flexlink Systems PEC EME K.U.Leuven Dept of Metall. & Mater. Eng Lab Agric Mach & Proc Entecom Systems Tecmate Intl. D2S International M&M Corporation Data Analys Products CSI Scala Consultants Mixed innovatieve bedrijven Donaldson LMS South Lancs Belgium Affilips Robert Bosch
  • 46.
    Life Science Cluster Kenniscentra E.S.R.I. DeckersDiv Dermat Centers of excellence Biotest Seralco Benelux Thrombogenics Tigenix Norgine IDT(RNA-TEC) Dakocytomation BioTie Therapies Corp. Univ hospitals K.U.Leuven Rega Institute CEHA Algonomics PatientWeb Medvision Benelux Puur innovatieve bedrijven Gemengd innovatieve bedrijven M-Elect M4S Materialise K.U.Leuven L-MTC Autocyte Europe Neurogenetics @Medical Techn. MXS VIB VIGOUR Custom8 Fugeia Malaise&co Terumo Europe Cochlear Lab of Exp. Genetics & Transgenese QMedit IVIA ReMynd Medicim CMPG Centocor Diatos Onco Methylome Regenesys New Standard Eng. Formac Pharmaceuticals VWR International Ortec Conti BPC
  • 47.
  • 48.
    Much more than the3 % Lisbon target
  • 49.
    HIGH TECH SYSTEMS& MATERIALEN Specialisatie en pieken: Selectie en typologie belangrijkste actoren TTR Nederland Nederlandse Vereniging voor Precisietechnologie Vereniging van de Nederlandse Chemische Industrie DSP Valley Sirris DAF nv Graco Siemens VDO Kenniscentra en centers of excellence Bosch Packaging FMTC (mechatronica) Vista nv Philips Chemelot Alro Holdings Ford Werke Bosch Hydraulic LAG Trailers Borealis Polymers Akzo Nobel Pure innovatieve bedrijven Netherlands Aerospace Group (NAG) ATC Eindhoven Mixed innovatieve bedrijven Océ Stork food systems en printing Campus Eindhoven Cerobear Verband der Chemischen industrie (VCI) KUL KUleuven UImec Hasselt Philips (licht)/ Philips Onderzoeksinstituut Trützschler FEV Motorentechnik Cluster Chemie/ Kunststoffe Mitteldeutschland INTRA e.V. * Internationaal netwerk: Automotive.net Tessenderlo chemie Forschungszentrum Jülich RWTH Hochschule Aachen Niederrhein Continental Schumag AG Spaas Kaarsen Prüfcentrum Siemens transportation Systems Agoria Heraeus Electro-Nite International Flanders Drive Oerlikon Textile Scheidt & Bachmann 3M Netwerken* DOW Belgium U Luik U Hasselt U Fraunhofer Institut Luik Siempelkamp FLAMAC (materialen onderzoek) Epiq Imec Philips DSM ASML Nederlandse vereniging voor rubber en kunststoffen Campus Geleen Nedcar Vanderlande Industries TTR België Walonie Espace Pierberg Voith Paper AUNDE Verband der Elektrotechnik (VDE) Munters Euroform CAR e.V. Verbundinitiative Automobil Nordrhein-Westfalen (VIA NRW) TTR Duitsland 49
  • 50.
    K.U.Leuven Spin offs 100 90 80 70 GemmaFrisius-Seed Capital 2x 12,5 m€ 60 50 40 30 20 10 0 1980 1982 1984 1986 1988 1990 1992 1994 1996 1998 2000 2002 2004 2006 2008 2010 2012
  • 51.
    Spillovers and multipliers •Spin-offs between 2006 - 2010: – K.U.Leuven direct investments: 4,7 M€ – Gemma Frisius Fund investments: 12 M€ – Other third party investments: 476 M€
  • 52.
    Perennial topics Investment inspin-offs 2005 - 2012 700 000 000 631 426 634 Euro 600 000 000 500 000 000 400 000 000 300 000 000 200 000 000 100 000 000 7 453 606 14 591 843 KU Leuven GFF 0 derden
  • 53.
     Seed Capital –Venture Capital – 500 million € Risicokapitaal Arr. Leuven (2002) : 200 miljoen euro Servifund 12% Gemma Frisius Fonds 1 7% Stonefund 19% Beluga 12% Softw are Holding & Finance 8% Gemma Frisius Fonds 2 7% IMEC Incubatiefonds 3% Capricorn Venture Partners 12% Quest Management 20%
  • 54.
    Spillovers and multipliers •Patent portfolios: – K.U.Leuven R&D, 454 active patent families of which 90% economically exploited – Multiplier effects of patent portfolios of spin-off companies  sectoral multipliers of 3 to 4
  • 55.
    Examples in LifeSciences KU Leuven
  • 56.
    Spin-off companies: someexamples • Engineering • Micro-electronics & ICT
  • 57.
    Spin-off companies: examples •Consultancy • Biomedical
  • 58.
    Incubation & seedfinancing • Gemma Frisius Fund KU Leuven (GFF) o o Seed capital for spin-off companies GFF founded in 1997 & GFF II in 2002 • o At the end of 2009 GFF and GFF II merged into one single fund Partners: • • o KU Leuven (20% of capital) Two banks: KBC Private Equity (40%) and BNP Paribas Fortis Private Equity (40%) Combination between: • • o o Knowledge and technology transfer expertise (university) Financial expertise (financial partners) Not restricted to one technology domain 25 million euro invested in 38 spin-off companies
  • 59.
    Regional and interregionaldevelopment • Partners: o o o o o o o o City of Leuven Province of Flemish Brabant Vinnof CREA - European Commission KBC Private Equity BNP Paribas Fortis Private Equity imec VIB • ELAt: Eindhoven - Leuven - Aachen triangle o o Cross-border and interregional network Stimulation of knowledge economy • HAE : Health Axis Europe (Heidelberg, Leuven, Cambridge)
  • 60.
    Networks • Stimulating knowledgeexchange and partnering with other high-tech businesses (both SMEs and large companies) and innovation actors • Horizontal networks: o o Leuven.Inc Flanders Smart Hub
  • 61.
    Networks • Vertical networks: o o DSPValley LSEC • Thematic centres: o o o o o o o CD3 L-MRC L-MTC LICT PharmAbs NERF LFoRCe
  • 62.
    Science parks, businesscentres & incubators • • • • • • • • Arenberg Science Park Haasrode Science Park Leuven Noord Science Park Waterschei - Genk Science Park Tienen Science Park Ubicenter Remy Campus Leuven Business Centre
  • 63.
    Science parks, businesscentres & incubators • • • • Leuven Bio-Incubators Tienen Biogenerator KU Leuven Innovation & Incubation Centre (I&I) Kortrijk Innovation & Incubation Centre (IICK)
  • 64.
  • 65.
    12 Lessons fromLeuven 1. Basis is a critical mass of high quality research 2. Create an appropriate entrepreneurial climate in a university context 3. Create a legal framework with respect to exploitation of academic research 4. Clear incentives and policies to encourage research groups and departments to actively seek knowledge transfer opportunities 5. Create a professional Interface Unit – An Integrated approach on research valorisation: multidisciplinary team & “high value” services 6. Create a Seed Capital and/or Venture Capital Fund
  • 66.
    12 Lessons fromLeuven 7. Foster spin-offs from your university research 8. Clear ownership of Intellectual Property 9. Improving awareness among federal, regional and local shareholders 10. Supporting a forum for business, academia, government and supporting organisations to build partnerships by sharing new ideas and best practices. Importance of the networks. 11. Focus on Focus and Enthusiasm 12. Quality of life
  • 67.
    Success factors • Acritical mass of high quality research • Multidisciplinary team & high value support • Clear incentives to encourage researchers and research groups • Favourable entrepreneurial climate within the university • Legal context in Flanders • Instruments and networks that further professionalise technology transfer support
  • 68.
    Towards an Entrepreneurial Society    “Therise of the entrepreneur is not just about economics. It reflects profound changes from individual careers to the social contract. It signals the birth of an entrepreneurial society” -The EconomistMarch 14, 2009
  • 69.
    The Value Chainis the barometer 1. Knowledge Centers 2. Entrepreneurs 3. Role Models 4. Money 5. Capital Markets 6. Infrastructure 7. Cluster Policy 8. International Companies 9. Networks 10. Government 11. Quality of Life Source : Hinoul, Gibbons, Saxenian
  • 70.
    What makes aregion attractive for talent?  Location – such as Silicon Valley, California – Sophia Antipolis, Mediteranée – Heidelberg Old University  Universities or Research Centers - Magnets for talent See Jiao Tong University League e.g. Stanford, Harvard, Princeton, IMEC Leuven, LETI Grenoble, CERN Geneva.  Presence of top Succesful Companies Microsoft, Intel, Google, ASML, LMS…  Presence of Strong Individuals – Role Models Bill Gates, Steve Jobs, Larry Page and even Nobel price winners.  Presence of Successful Clusters San Diego Biotech-Golden Triangle – North Carolina Research triangle  Fiscal System – Salaries, tax incentives, research budgets  Quality of Life – Leisure, Housing, Medical care, International schools, culture… Source: M. Hinoul – 7th Annual Conference – Technopolicy Network – Heidelberg 2010
  • 71.
    Towards a newForm of Culture All things are possible attitude Risk Taking We have not enough spin-offs who fail Co-competition Stock options Based on Meritocracy Serial Entrepreneurs Time for the next big thing CULTURE Cross-pollination Inflection Point (Andy Grove) Cross-investments State of mind Networking Jumping on the Next Curve (Oracle) Failure Badge of merit Source : M. Hinoul ±
  • 72.
    Flemish Entrepreneurs The oldgeneration Leo Leander Bekaert Lieven Gevaert Leo H. Baekeland 75
  • 73.
    Flemish Visionaries Gaston Geens JohnCordier Paul Janssen Roger Van Overstraeten Marc Van Montagu Walter Fiers 76
  • 74.
    Leuven Entrepreneurs A newgeneration . A.OOSTERLINCK J. DEJAEGER D. COLLEN P. STOFFELS S. BIJNENS U. VAN DEURZEN J. CALLEWAERT B. VAN COPPENOLLE F. VAN CRAEN T. DE PROFT
  • 77.
    Speech recognition Data screening Microelectronics Cloud computing Components Interplanetary Space Flights Ground Navigation Suborbital Space flights Small satellites Platform & pay load Nuclear Medicine Medical devices Drug Delivery Bio Informatics Stemcells Interdisciplinary Research Clusters and Research Directions Confidential-M.Hinoul
  • 78.
    Clusters and InterdisciplinaryResearch at Skolkovo Director TTO  Research Collaboration  IPR(Royalties,Licencing)  Spin offs – Start ups  Finance (Seed, VC, IPO) 5 Research Programs (Clusters) Research Centers Interdisciplinary approach A close interaction between different research divisions Technopark (a state of the art infrastructure) Russian & International Cies Russian & International Research Centers
  • 79.
    Dual Incentive Mechanism Russian& International Universities Russian & International Cies SIST Technopark  Striving for scientific excellence  Gearing this excellence towards application and technological innovation Creation of the Knowledge Economy Region Skolkovo
  • 80.
    Contact KU Leuven Research& Development (LRD) Waaistraat 6 – box 5105 3000 Leuven, Belgium Tel.+32 16 32 65 00 lrd@kuleuven.be lrd.kuleuven.be