The document discusses the biological basis of behavior and the nervous system. It covers topics such as neurons, synaptic transmission, the divisions of the brain including the cerebral cortex and limbic system, and the peripheral and autonomic nervous systems. The biological foundations of the mind, emotions, and mental processes are examined.
1. “I never teach my pupils, I only attempt to
provide the conditions in which they can
learn.”
2. The Biological Basis of BehaviorThe Biological Basis of Behavior
Chapter 2
Presented by: Ahmed Nagy, BSc. Pharmacy
Teaching Assistant, BMS, Zewail city
17. Neural Plasticity and Neurogenesis
Experience can lead to significant changes in number
of complexity of synaptic connections in brain
Professor Mark R. Rosenzweig
25. • The Limbic System – fully developed only
in mammals, it plays a role in learning and
emotional behavior.
• Hippocampus – plays an essential role in
the formation of new memories.
• Amygdala – governs and regulates
emotions and establishes emotional
memories.
28. • The peripheral nervous system links the
brain and spinal cord to the rest of the
body. It consists of:
• Afferent Neurons – carry messages
from the sense organs to the spinal cord
and brain.
• Efferent Neurons – carry messages
from the spinal cord and brain to the
muscles and glands.
30. • The peripheral nervous system is subdivided
into:
• Somatic Nervous System – contains the
sensory pathway, or neurons carrying
messages to the central nervous system,
and the motor pathway, or neurons carrying
messages from the central nervous system
to the voluntary muscles.
• Autonomic Nervous System – carries
messages between the central nervous
system and the internal organs, governing
involuntary activities.
32. • The autonomic nervous system consists
of the parasympathetic division and the
sympathetic division :
• Sympathetic Division – comprises our
fight-or-flight system, preparing us to
react to stress.
• Parasympathetic Division – restores
and maintains normal day-to-day
functioning of the organs, calming the
body after it reacts to stress.
The brain of an average human being contains as many as 100 billion nerve cells or neurons.
Neurons vary in size and shape, but they are all specialized to receive and transmit information.
Sensory (or afferent) neurons - neurons that carry messages from sense organs to spinal cord or brain
Motor (or efferent) neurons - neurons that carry messages from spinal cord or brain to muscles and glands
Interneurons (or association neurons) - neurons that carry messages from one neuron to another
Mirror neurons - specialized neurons that respond when we observe others perform a behavior or express an emotion
Glial cells (or glia) - cells that insulate and support neurons by holding them together, provide nourishment and remove waste products, prevent harmful substances from passing into brain, and form myelin sheath
Action potential - firing of nerve cell
Resting potential - electrical charge across neuron membrane as result of positive ions outside and negative ions inside membrane
Polarization - condition of neuron when inside is negatively charged relative to outside; when neuron is at rest
Ions - Electrically charged particles found both inside and outside neuron
Synaptic transmission
Neurotransmitter molecules, released by synaptic vesicles, cross the tiny synaptic space (or cleft) between an axon terminal (or terminal button) of a sending neuron and a dendrite of a receiving neuron.
The neurotransmitters cross the synaptic space.
Here they latch on to receptor sites, much as keys fit into locks, and pass on their excitatory or inhibitory messages.
Neural plasticity
The ability of brain to be changed structurally and chemically by experience.
Rosenzweig (1984) demonstrated the importance of experience to neural development
Rats raised in more complex environments had larger neurons and more synaptic connections
Other research has found those rats raised in more complex environments are better at solving problems
The brain changes in response to experience.
This appears to happen as a response to expertise (e.g. practicing the violin).
The strength of the response varies as well as the amount.
Adult brains are capable of neurogenesis− the creation of neurons over the course of one’s lifetime.
This finding has lead to new research into the potential to grow cells to replace damaged cells
or finding ways to encourage damaged cells to repair themselves.
In Rosenzweig’s experiment, young rats lived in two kinds of cages “impoverished,” with nothing to manipulate or explore or “enriched,” with a variety of objects. When Rosenzweig examined the rats’ brains, he found that the enriched group had larger neurons with synaptic connections (shown as dendrites in the drawing) than the rats that lived in the bare cages. Experience, then, can actually affect the structure of the brain.
The nervous system is organized into two parts:
The central nervous system (CNS), which consists of the brain and spinal cord.
The peripheral nervous system (PNS), is made up of nerves that radiate throughout the body, linking all of the body's parts to the CNS.
A schematic diagram of the divisions of the nervous system and their various subparts.
Physically, the brain has three more or less distinct areas:
The central core
The limbic system
The cerebrum
Hindbrain
Medulla: Controls breathing, heart rate, blood pressure
Pons: Regulation of sleep/wake cycle
Cerebellum: Involved in balance and coordination of movement
Midbrain
The relay point for hearing and vision
One of the places pain is registered
Brain structures found in midbrain: superior colliculus, inferior colliculus, substantia nigra
Forebrain structures
Thalamus: Sensory switchboard
Hypothalamus: Governs motivational (hunger, thirst, sex, sleep, and temperature control) and emotional responses
Reticular formation
A network of neurons in the hindbrain, midbrain, and part of the forebrain
The primary function of this network is to alert and arouse the higher parts of the brain
Cerebral cortex has four lobes (see next slide)
Deep fissures in the cortex separate these areas or lobes. Also shown are the primary somatosensor and motor areas.
Limbic system
System of loosely connected structures located between the central core and the cerebral hemispheres
Linked primarily to memory, emotions, drives
Appears to play a central role in times of stress
Hippocampus: Aids in the processing of memory for storage
Amygdala: Involved in fear and aggression
Hypothalamus: Bodily maintenance functions and pleasurable rewards
Afferent neurons - carry messages from sense organs to spinal cord and brain
Efferent neurons - carry messages from spinal cord to brain
The peripheral nervous system (PNS)
Contains two types of neurons:
Afferent neurons, which carry sensory messages to the central nervous system,
Efferent neurons, which carry messages from the CNS
PNS is divided into two subsystems
Somatic nervous system
Has neurons involved in making voluntary movements of the skeletal muscles
Autonomic nervous system
Has neurons involved in governing the actions of internal organs
Sympathetic division - branch of autonomic nervous system; it prepares body for quick action in an emergency
Parasympathetic division - branch of autonomic nervous system; it calms and relaxes body
Autonomic Nervous System
The autonomic nervous system is divided into two parts:
The sympathetic division, which acts primarily to arouse the body when it is faced with threat, and
The parasympathetic division, which acts to calm the body down, restoring it to normal levels of arousal
Sympathetic division
Dilates pupils
No effect on tear glands
Weak stimulation of salivary flow
Accelerates heart, constricts arterioles
Dilates bronchi
Inhibits stomach motility and secretions
Parasympathetic division
Constricts pupils
Stimulates tear glands
Strong stimulation of salivary flow
Inhibits heart, dilates arterioles
Constricts bronchi
Stimulates stomach motility & secretion
Endocrine system works in conjunction with nervous system
Endocrine glands- tissues that produce and release hormones
Hormones - chemical substances released by glands that help regulate bodily activities
Genes, Evolution, & Behavior
The related fields of behavior genetics and evolutionary psychology explore the influences of heredity on human behavior
Both are helping to settle the nature/nurture debate over the relative contributions of genes and the environment to human similarities and differences
Two different but related fields contribute to the understanding on influence of heredity on behavior
Behavioral genetics - study of relationship between heredity and behavior
Evolutionary psychology - study of evolutionary roots of behaviors and mental processes