MHC.pptx
•Download as PPTX, PDF•
1 like•39 views
The major histocompatibility complex (MHC) is a set of surface proteins located on nucleated cells that plays an important role in distinguishing self from non-self and antigen presentation. There are two types of MHC molecules: class I MHC molecules present antigens to cytotoxic T cells on all nucleated cells, while class II MHC molecules present antigens to helper T cells and are found only on antigen-presenting cells. Both MHC classes consist of a transmembrane alpha chain and beta chain that form a peptide-binding groove to load and present antigen peptides. MHC molecules allow the immune system to recognize foreign substances so the body's immune response can be triggered.
Report
Share
Report
Share
Recommended
Immunology MHC.pptx
The major histocompatibility complex (MHC) molecules are membrane-bound glycoproteins that function as specialized antigen-presenting molecules. There are two main classes of MHC molecules - class I and class II. Class I molecules present intracellularly derived antigens to CD8+ T cells, while class II molecules present extracellular antigens engulfed by antigen-presenting cells to CD4+ T cells. Both classes of MHC molecules form stable complexes with peptide ligands within a binding groove and display them on the cell surface for recognition by T-cell receptors.
Major histocompatibility complex CH.U
The major histocompatibility complex (MHC) is a collection of genes that encode glycoproteins found on the surface of mammalian cells. MHC proteins present antigens and help the immune system distinguish self from nonself. There are two major classes of MHC molecules: class I molecules present antigens to cytotoxic T cells on all nucleated cells, while class II molecules present antigens to helper T cells on antigen-presenting cells that have engulfed foreign antigens. Together, MHC molecules play a key role in cell-cell interaction and initiating adaptive immune responses.
MHC lecture.pptx
The document summarizes the major histocompatibility complex (MHC), which screens T cells so that only those capable of binding to MHC molecules are maintained. It discusses MHC restriction, whereby a T cell only recognizes a peptide bound to a particular MHC variant. MHC molecules are highly polymorphic, affecting the range of bound peptides and interactions with T cell receptors. MHC class I presents intracellular peptides to cytotoxic T cells, while MHC class II presents extracellular peptides to T helper cells, leading to different immune responses.
Antigen Presentation Pathways.pptx
MHC class I and II molecules are membrane-bound glycoproteins that present antigen peptide fragments to T cells. MHC class I presents endogenous antigens processed via the cytosolic pathway to CD8+ cytotoxic T cells, while MHC class II presents exogenous antigens endocytosed and processed via the endocytic pathway to CD4+ helper T cells. The cytosolic pathway involves proteolytic degradation of antigens in the cytosol and transport of peptides to the ER for assembly with class I MHC. The endocytic pathway involves internalization of exogenous antigens, processing in endosomes, transport of class II MHC to endosomes, and assembly of antigen peptides with class II MHC.
Antigen processing and MHC
1. The MHC molecules present peptide antigens to T cells. Class I MHC present intracellular peptides to CD8+ T cells, while class II MHC present extracellular peptides taken up by endocytosis to CD4+ T cells.
2. Antigens are processed through different pathways depending on if they are intracellular or extracellular. Intracellular antigens are degraded by the proteasome and transported into the ER by TAP to bind class I MHC. Extracellular antigens are endocytosed and degraded in lysosomes to bind class II MHC.
3. The peptide-MHC complexes are then transported to the cell surface for recognition by T cell receptors.
Major Histocompatibility complex
The seminar presented discussed the major histocompatibility complex (MHC). MHC molecules are surface proteins located on nucleated cells that play an important role in identifying antigens and presenting them to T cells to trigger an immune response. The seminar covered the definition of MHC, its history of discovery, the different classes of MHC molecules including their structure and function, examples in humans (HLA) and mice (H-2 complex), and concluded with a summary of how MHC molecules recognize both endogenous and exogenous antigens to initiate an immune response. The seminar was presented by Miss. Sandhya Sahu and guided by her professor Mr. Shishir Vind Sharma at Rungta College of Science & Technology,
MHC--M.Sc--III sem--07.07.20.pptx
The Major Histocompatibility Complex (MHC) refers to a set of genes that code for MHC proteins found on the surfaces of cells. These proteins help the immune system recognize foreign substances by presenting antigen fragments to T cells. There are three main classes of MHC molecules: class I molecules present antigens to CD8+ T cells on nearly all nucleated cells; class II molecules present antigens to CD4+ T cells and are found on antigen-presenting cells; class III molecules encode for other immune system proteins. MHC molecules have a groove that binds peptides for presentation to T cells, allowing the immune system to detect infected or damaged cells.
MHC- Major Histocompactibility complex -Definition, classification, structure...
MHC- Major Histocompactibility complex -Definition, classification, structure and functions of MHC as per PCI syllabus
Recommended
Immunology MHC.pptx
The major histocompatibility complex (MHC) molecules are membrane-bound glycoproteins that function as specialized antigen-presenting molecules. There are two main classes of MHC molecules - class I and class II. Class I molecules present intracellularly derived antigens to CD8+ T cells, while class II molecules present extracellular antigens engulfed by antigen-presenting cells to CD4+ T cells. Both classes of MHC molecules form stable complexes with peptide ligands within a binding groove and display them on the cell surface for recognition by T-cell receptors.
Major histocompatibility complex CH.U
The major histocompatibility complex (MHC) is a collection of genes that encode glycoproteins found on the surface of mammalian cells. MHC proteins present antigens and help the immune system distinguish self from nonself. There are two major classes of MHC molecules: class I molecules present antigens to cytotoxic T cells on all nucleated cells, while class II molecules present antigens to helper T cells on antigen-presenting cells that have engulfed foreign antigens. Together, MHC molecules play a key role in cell-cell interaction and initiating adaptive immune responses.
MHC lecture.pptx
The document summarizes the major histocompatibility complex (MHC), which screens T cells so that only those capable of binding to MHC molecules are maintained. It discusses MHC restriction, whereby a T cell only recognizes a peptide bound to a particular MHC variant. MHC molecules are highly polymorphic, affecting the range of bound peptides and interactions with T cell receptors. MHC class I presents intracellular peptides to cytotoxic T cells, while MHC class II presents extracellular peptides to T helper cells, leading to different immune responses.
Antigen Presentation Pathways.pptx
MHC class I and II molecules are membrane-bound glycoproteins that present antigen peptide fragments to T cells. MHC class I presents endogenous antigens processed via the cytosolic pathway to CD8+ cytotoxic T cells, while MHC class II presents exogenous antigens endocytosed and processed via the endocytic pathway to CD4+ helper T cells. The cytosolic pathway involves proteolytic degradation of antigens in the cytosol and transport of peptides to the ER for assembly with class I MHC. The endocytic pathway involves internalization of exogenous antigens, processing in endosomes, transport of class II MHC to endosomes, and assembly of antigen peptides with class II MHC.
Antigen processing and MHC
1. The MHC molecules present peptide antigens to T cells. Class I MHC present intracellular peptides to CD8+ T cells, while class II MHC present extracellular peptides taken up by endocytosis to CD4+ T cells.
2. Antigens are processed through different pathways depending on if they are intracellular or extracellular. Intracellular antigens are degraded by the proteasome and transported into the ER by TAP to bind class I MHC. Extracellular antigens are endocytosed and degraded in lysosomes to bind class II MHC.
3. The peptide-MHC complexes are then transported to the cell surface for recognition by T cell receptors.
Major Histocompatibility complex
The seminar presented discussed the major histocompatibility complex (MHC). MHC molecules are surface proteins located on nucleated cells that play an important role in identifying antigens and presenting them to T cells to trigger an immune response. The seminar covered the definition of MHC, its history of discovery, the different classes of MHC molecules including their structure and function, examples in humans (HLA) and mice (H-2 complex), and concluded with a summary of how MHC molecules recognize both endogenous and exogenous antigens to initiate an immune response. The seminar was presented by Miss. Sandhya Sahu and guided by her professor Mr. Shishir Vind Sharma at Rungta College of Science & Technology,
MHC--M.Sc--III sem--07.07.20.pptx
The Major Histocompatibility Complex (MHC) refers to a set of genes that code for MHC proteins found on the surfaces of cells. These proteins help the immune system recognize foreign substances by presenting antigen fragments to T cells. There are three main classes of MHC molecules: class I molecules present antigens to CD8+ T cells on nearly all nucleated cells; class II molecules present antigens to CD4+ T cells and are found on antigen-presenting cells; class III molecules encode for other immune system proteins. MHC molecules have a groove that binds peptides for presentation to T cells, allowing the immune system to detect infected or damaged cells.
MHC- Major Histocompactibility complex -Definition, classification, structure...
MHC- Major Histocompactibility complex -Definition, classification, structure and functions of MHC as per PCI syllabus
Major histocompatibility complex
The major histocompatibility complex (MHC) is a collection of genes on chromosome 6 in humans that code for MHC molecules. MHC molecules are divided into three classes: class I molecules are found on almost all nucleated cells and present intracellular peptides; class II molecules are found on antigen-presenting cells and present extracellular peptides; class III molecules are secreted proteins with immune functions like complement components. MHC molecules present peptide fragments to T cells to trigger immune responses and also determine compatibility for organ transplants.
5. MHC.ppt
Major Histocompatibility Complex (MHC) molecules present peptide antigens to T cells and are highly polymorphic. MHC molecules are classified into three main classes - Class I molecules present intracellular peptides to CD8+ T cells, Class II present extracellular peptides to CD4+ T cells, and Class III genes encode complement proteins. MHC molecules have a peptide-binding groove that binds short peptides for presentation to T cells. MHC polymorphism generates a diverse repertoire of molecules that can present a wide variety of peptides and mount immune responses against pathogens.
MHC major histocompatibility complex
The document discusses the major histocompatibility complex (MHC), which are surface proteins that play an important role in identifying antigens and presenting them to T cells. It covers the different classes of MHC molecules, their structures, functions in immunity, and examples in humans (HLA) and mice (H-2 complex). MHC molecules present peptide fragments on their surface and interact specifically with T cells through anchor residues on the peptides. They are essential for self/non-self discrimination, defense against infection, and transplantation compatibility.
MAJOR HISTOCOMPATIBILITY COMPLEX M.MANIKANDAN.pptx
The Major Histocompatibility Complex (MHC) is a set of surface proteins located on nucleated cells that present antigens and play an important role in the immune system. There are four classes of MHC molecules - Class I molecules present intracellular antigens to cytotoxic T cells, Class II present extracellular antigens to helper T cells, and Classes III and IV have other immune functions. MHC molecules are encoded by genes on chromosome 6 in humans and chromosome 17 in mice, and are important for self/non-self recognition, immune responses, and tissue compatibility.
Major histocompatility complex (Antigen Presentation to T cells, Autoimmunity...
Major histocompatility complex (Antigen Presentation to T cells, Autoimmunity...Pradeep Singh Narwat
The document provides an overview of major histocompatibility complex (MHC) molecules, including their history, structure, organization and inheritance, and functions in antigen presentation and immune responses. MHC molecules are membrane-bound glycoproteins that are encoded by genes in the MHC locus and present antigen peptides to T cells to initiate adaptive immune responses against intracellular and extracellular pathogens.12 cellular basis of imune response
1) Antigen processing and presentation involves extracellular and intracellular proteins being degraded into peptides and bound to MHC class I or II molecules. These peptide-MHC complexes are expressed on antigen presenting cells and recognized by T cells to initiate an immune response.
2) T cells are activated through recognition of peptide-MHC complexes by their T cell receptors along with co-stimulatory signals. Activated T cells proliferate and differentiate into effector and memory T cells.
3) Effector T cells stimulate immune responses like activating macrophages to kill intracellular pathogens, leading to delayed type hypersensitivity reactions which can cause tissue damage if infection is not resolved.
MHC I molecules
All of the information are collected , it's not a research work but I think it will help the students to know about the basic information.
A Short Note on MHC Molecules
The document provides information about MHC molecules. It discusses that MHC molecules are classified into two types - Class I and Class II. Class I molecules are expressed on all nucleated cells and present intracellularly derived peptides to CD8+ T cells. Class II molecules are only expressed on antigen presenting cells and present extracellularly derived peptides to CD4+ T cells. It describes the structure of Class I and Class II molecules and the pathways of antigen processing and loading of peptides onto MHC molecules. It also discusses T cell recognition of peptide-MHC complexes and the process of cross-presentation.
L6.0 Immune recognition molecule (MHC,T cell receptor, T cell epitopes, T cel...
The document discusses immune recognition molecules, focusing on major histocompatibility complex (MHC), T-cell receptors, T-cell epitopes, T-cell markers, B-cell epitopes, and Toll-like receptors. It describes how MHC molecules present antigen peptides to T cells to initiate immune responses. MHC class I molecules present intracellular peptides to CD8+ T cells, while class II molecules present extracellular peptides to CD4+ T cells. MHC molecules bind peptides through their peptide-binding cleft in a polymorphic and promiscuous manner. Very few peptide-MHC complexes are needed to activate antigen-specific T cells.
MHC.pptx
The Major Histocompatibility Complex (MHC) is a set of genes located on chromosome 6 that encode MHC molecules displayed on cell surfaces. MHC molecules control the immune response through recognition of self and non-self antigens. There are two main classes of MHC molecules - Class I molecules present intracellular peptides to CD8+ T cells, while Class II molecules present extracellular peptides internalized by antigen presenting cells to CD4+ T cells. MHC molecules play a crucial role in the immune system through antigen presentation and recognition.
STRUCTURE AND FUNCTIONS OF MHC
Major Histocompatibility Complex (MHC) antigens are a set of cell surface proteins essential for the acquired immune system to identify foreign molecules. MHC antigens bind to pathogen antigens and display them on the cell surface for identification by T-cells. MHC is a cluster of genes on chromosome 6 in humans that encodes these antigens. There are three classes of MHC - Class I presents antigens to CD8 T-cells on all nucleated cells, Class II presents antigens to CD4 T-cells on antigen presenting cells like macrophages, and Class III plays a role in immune function through complement and cytokines. MHC antigens act as antigen presenting structures and play important roles in immune responses, transplantation tissue matching, and autoimmune diseases.
Major Histocompatibility Complex
Major Histocompatibility Complex (MHC) molecules display antigen peptides on the surface of cells to be recognized by T cells. There are two main types of MHC molecules: class I molecules present intracellular peptides to CD8+ T cells on most nucleated cells, while class II molecules present extracellular peptides to CD4+ T cells on antigen-presenting cells like dendritic cells and macrophages. MHC molecules bind peptides promiscuously but polymorphisms among individuals influence peptide binding. Dendritic cells are especially effective at antigen capture and presentation to initiate primary T cell responses.
MAJOR HISTOCOMPATIBILITY COMPLEX by Pranzly.ppt
The document discusses the major histocompatibility complex (MHC), which encodes MHC molecules that act as antigen presenting structures. MHC molecules are classified into three classes - MHC class I molecules present endogenous antigens to CD8+ T cells, MHC class II molecules present exogenous antigens to CD4+ T cells and are expressed on antigen presenting cells, and MHC class III molecules encode complement proteins. The document describes the structure, mechanism of antigen presentation, and functions of MHC class I and class II molecules.
Major histocompatibility complex
The major histocompatibility complex (MHC) is a cluster of genes found in all mammals that encodes proteins important for the immune system to distinguish self from non-self. MHC molecules are expressed on the cell surface and present peptide antigens to T cells. There are three main classes of MHC genes - class I presents endogenous peptides to cytotoxic T cells, class II presents exogenous peptides to helper T cells, and class III encodes non-antigen presenting proteins involved in immunity. MHC molecules have binding sites that allow them to bind a variety of peptide antigens through anchor residues, helping the immune system recognize a diverse array of pathogens. Polymorphism of MHC alleles within populations helps provide protection against rapidly mutating pathogens.
MHC PPT.pptx
Class I and class II MHC molecules bind antigenic peptides derived from degraded antigens. MHC molecules present antigen peptides to T cells but do not have the fine specificity of antibodies or T cell receptors. The distal regions of MHC molecules display allelic variation that results in different antigen-binding clefts with varying specificities. For an antigen to be recognized by T cells, it must be degraded into peptides that form complexes with class I or class II MHC molecules on the cell surface in a process called antigen processing and presentation.
L3 MHC.pdf
The document discusses the major histocompatibility complex (MHC) and T cell-mediated immunity. It describes how MHC molecules present antigen peptides on the surface of antigen-presenting cells to activate T cells. MHC class I molecules present peptides to CD8 T cells, while MHC class II molecules present peptides to CD4 T cells. Polymorphism in MHC genes allows for a diverse repertoire of MHC molecules between individuals, helping populations resist rapidly mutating pathogens.
Major Histocompatibility Complex.ppt
The document summarizes the major histocompatibility complex (MHC), which encodes proteins that play a role in self/non-self discrimination. It describes the structure and function of MHC class I and class II molecules. MHC class I presents endogenous antigens to CD8+ T cells, consisting of an alpha chain, beta-2 microglobulin chain, and a short peptide. MHC class II presents exogenous antigens to CD4+ T cells, consisting of alpha and beta chains that bind longer peptides. Both are membrane-bound glycoproteins that present antigen to T cells via peptide-binding clefts.
IGNTU-eContent-392458762550-B.Sc-Biotechnology-4-Dr.PrashantKumarSingh-IMMUNO...
The major histocompatibility complex (MHC) is a cluster of genes located on chromosome 6 in humans that encodes proteins involved in the immune system's recognition of self and non-self. The MHC includes class I, II, and III genes. Class I genes produce molecules that present intracellular peptides to cytotoxic T cells, while class II genes produce molecules that present extracellular peptides to helper T cells. Antigens are processed through either the cytosolic or endocytic pathway and bound to MHC molecules to be presented at the cell surface for recognition by T cells.
Anti Radiation Vaccine technology.
The document discusses an anti-radiation vaccine technology involving Dmitri Popov, Maliev Slava, and Jeffrey Jones. It summarizes the roles of white blood cells (leukocytes) and their organelles (lysosomes) in presenting antigen peptides through MHC class I and II molecules to activate immune responses. Specifically, it describes how lysosome-associated membrane proteins (LAMPs) are involved in antigen processing and presentation to T cells to stimulate immune defenses against radiation and infectious agents.
More Related Content
Similar to MHC.pptx
Major histocompatibility complex
The major histocompatibility complex (MHC) is a collection of genes on chromosome 6 in humans that code for MHC molecules. MHC molecules are divided into three classes: class I molecules are found on almost all nucleated cells and present intracellular peptides; class II molecules are found on antigen-presenting cells and present extracellular peptides; class III molecules are secreted proteins with immune functions like complement components. MHC molecules present peptide fragments to T cells to trigger immune responses and also determine compatibility for organ transplants.
5. MHC.ppt
Major Histocompatibility Complex (MHC) molecules present peptide antigens to T cells and are highly polymorphic. MHC molecules are classified into three main classes - Class I molecules present intracellular peptides to CD8+ T cells, Class II present extracellular peptides to CD4+ T cells, and Class III genes encode complement proteins. MHC molecules have a peptide-binding groove that binds short peptides for presentation to T cells. MHC polymorphism generates a diverse repertoire of molecules that can present a wide variety of peptides and mount immune responses against pathogens.
MHC major histocompatibility complex
The document discusses the major histocompatibility complex (MHC), which are surface proteins that play an important role in identifying antigens and presenting them to T cells. It covers the different classes of MHC molecules, their structures, functions in immunity, and examples in humans (HLA) and mice (H-2 complex). MHC molecules present peptide fragments on their surface and interact specifically with T cells through anchor residues on the peptides. They are essential for self/non-self discrimination, defense against infection, and transplantation compatibility.
MAJOR HISTOCOMPATIBILITY COMPLEX M.MANIKANDAN.pptx
The Major Histocompatibility Complex (MHC) is a set of surface proteins located on nucleated cells that present antigens and play an important role in the immune system. There are four classes of MHC molecules - Class I molecules present intracellular antigens to cytotoxic T cells, Class II present extracellular antigens to helper T cells, and Classes III and IV have other immune functions. MHC molecules are encoded by genes on chromosome 6 in humans and chromosome 17 in mice, and are important for self/non-self recognition, immune responses, and tissue compatibility.
Major histocompatility complex (Antigen Presentation to T cells, Autoimmunity...
Major histocompatility complex (Antigen Presentation to T cells, Autoimmunity...Pradeep Singh Narwat
The document provides an overview of major histocompatibility complex (MHC) molecules, including their history, structure, organization and inheritance, and functions in antigen presentation and immune responses. MHC molecules are membrane-bound glycoproteins that are encoded by genes in the MHC locus and present antigen peptides to T cells to initiate adaptive immune responses against intracellular and extracellular pathogens.12 cellular basis of imune response
1) Antigen processing and presentation involves extracellular and intracellular proteins being degraded into peptides and bound to MHC class I or II molecules. These peptide-MHC complexes are expressed on antigen presenting cells and recognized by T cells to initiate an immune response.
2) T cells are activated through recognition of peptide-MHC complexes by their T cell receptors along with co-stimulatory signals. Activated T cells proliferate and differentiate into effector and memory T cells.
3) Effector T cells stimulate immune responses like activating macrophages to kill intracellular pathogens, leading to delayed type hypersensitivity reactions which can cause tissue damage if infection is not resolved.
MHC I molecules
All of the information are collected , it's not a research work but I think it will help the students to know about the basic information.
A Short Note on MHC Molecules
The document provides information about MHC molecules. It discusses that MHC molecules are classified into two types - Class I and Class II. Class I molecules are expressed on all nucleated cells and present intracellularly derived peptides to CD8+ T cells. Class II molecules are only expressed on antigen presenting cells and present extracellularly derived peptides to CD4+ T cells. It describes the structure of Class I and Class II molecules and the pathways of antigen processing and loading of peptides onto MHC molecules. It also discusses T cell recognition of peptide-MHC complexes and the process of cross-presentation.
L6.0 Immune recognition molecule (MHC,T cell receptor, T cell epitopes, T cel...
The document discusses immune recognition molecules, focusing on major histocompatibility complex (MHC), T-cell receptors, T-cell epitopes, T-cell markers, B-cell epitopes, and Toll-like receptors. It describes how MHC molecules present antigen peptides to T cells to initiate immune responses. MHC class I molecules present intracellular peptides to CD8+ T cells, while class II molecules present extracellular peptides to CD4+ T cells. MHC molecules bind peptides through their peptide-binding cleft in a polymorphic and promiscuous manner. Very few peptide-MHC complexes are needed to activate antigen-specific T cells.
MHC.pptx
The Major Histocompatibility Complex (MHC) is a set of genes located on chromosome 6 that encode MHC molecules displayed on cell surfaces. MHC molecules control the immune response through recognition of self and non-self antigens. There are two main classes of MHC molecules - Class I molecules present intracellular peptides to CD8+ T cells, while Class II molecules present extracellular peptides internalized by antigen presenting cells to CD4+ T cells. MHC molecules play a crucial role in the immune system through antigen presentation and recognition.
STRUCTURE AND FUNCTIONS OF MHC
Major Histocompatibility Complex (MHC) antigens are a set of cell surface proteins essential for the acquired immune system to identify foreign molecules. MHC antigens bind to pathogen antigens and display them on the cell surface for identification by T-cells. MHC is a cluster of genes on chromosome 6 in humans that encodes these antigens. There are three classes of MHC - Class I presents antigens to CD8 T-cells on all nucleated cells, Class II presents antigens to CD4 T-cells on antigen presenting cells like macrophages, and Class III plays a role in immune function through complement and cytokines. MHC antigens act as antigen presenting structures and play important roles in immune responses, transplantation tissue matching, and autoimmune diseases.
Major Histocompatibility Complex
Major Histocompatibility Complex (MHC) molecules display antigen peptides on the surface of cells to be recognized by T cells. There are two main types of MHC molecules: class I molecules present intracellular peptides to CD8+ T cells on most nucleated cells, while class II molecules present extracellular peptides to CD4+ T cells on antigen-presenting cells like dendritic cells and macrophages. MHC molecules bind peptides promiscuously but polymorphisms among individuals influence peptide binding. Dendritic cells are especially effective at antigen capture and presentation to initiate primary T cell responses.
MAJOR HISTOCOMPATIBILITY COMPLEX by Pranzly.ppt
The document discusses the major histocompatibility complex (MHC), which encodes MHC molecules that act as antigen presenting structures. MHC molecules are classified into three classes - MHC class I molecules present endogenous antigens to CD8+ T cells, MHC class II molecules present exogenous antigens to CD4+ T cells and are expressed on antigen presenting cells, and MHC class III molecules encode complement proteins. The document describes the structure, mechanism of antigen presentation, and functions of MHC class I and class II molecules.
Major histocompatibility complex
The major histocompatibility complex (MHC) is a cluster of genes found in all mammals that encodes proteins important for the immune system to distinguish self from non-self. MHC molecules are expressed on the cell surface and present peptide antigens to T cells. There are three main classes of MHC genes - class I presents endogenous peptides to cytotoxic T cells, class II presents exogenous peptides to helper T cells, and class III encodes non-antigen presenting proteins involved in immunity. MHC molecules have binding sites that allow them to bind a variety of peptide antigens through anchor residues, helping the immune system recognize a diverse array of pathogens. Polymorphism of MHC alleles within populations helps provide protection against rapidly mutating pathogens.
MHC PPT.pptx
Class I and class II MHC molecules bind antigenic peptides derived from degraded antigens. MHC molecules present antigen peptides to T cells but do not have the fine specificity of antibodies or T cell receptors. The distal regions of MHC molecules display allelic variation that results in different antigen-binding clefts with varying specificities. For an antigen to be recognized by T cells, it must be degraded into peptides that form complexes with class I or class II MHC molecules on the cell surface in a process called antigen processing and presentation.
L3 MHC.pdf
The document discusses the major histocompatibility complex (MHC) and T cell-mediated immunity. It describes how MHC molecules present antigen peptides on the surface of antigen-presenting cells to activate T cells. MHC class I molecules present peptides to CD8 T cells, while MHC class II molecules present peptides to CD4 T cells. Polymorphism in MHC genes allows for a diverse repertoire of MHC molecules between individuals, helping populations resist rapidly mutating pathogens.
Major Histocompatibility Complex.ppt
The document summarizes the major histocompatibility complex (MHC), which encodes proteins that play a role in self/non-self discrimination. It describes the structure and function of MHC class I and class II molecules. MHC class I presents endogenous antigens to CD8+ T cells, consisting of an alpha chain, beta-2 microglobulin chain, and a short peptide. MHC class II presents exogenous antigens to CD4+ T cells, consisting of alpha and beta chains that bind longer peptides. Both are membrane-bound glycoproteins that present antigen to T cells via peptide-binding clefts.
IGNTU-eContent-392458762550-B.Sc-Biotechnology-4-Dr.PrashantKumarSingh-IMMUNO...
The major histocompatibility complex (MHC) is a cluster of genes located on chromosome 6 in humans that encodes proteins involved in the immune system's recognition of self and non-self. The MHC includes class I, II, and III genes. Class I genes produce molecules that present intracellular peptides to cytotoxic T cells, while class II genes produce molecules that present extracellular peptides to helper T cells. Antigens are processed through either the cytosolic or endocytic pathway and bound to MHC molecules to be presented at the cell surface for recognition by T cells.
Anti Radiation Vaccine technology.
The document discusses an anti-radiation vaccine technology involving Dmitri Popov, Maliev Slava, and Jeffrey Jones. It summarizes the roles of white blood cells (leukocytes) and their organelles (lysosomes) in presenting antigen peptides through MHC class I and II molecules to activate immune responses. Specifically, it describes how lysosome-associated membrane proteins (LAMPs) are involved in antigen processing and presentation to T cells to stimulate immune defenses against radiation and infectious agents.
Similar to MHC.pptx (20)
MAJOR HISTOCOMPATIBILITY COMPLEX M.MANIKANDAN.pptx
MAJOR HISTOCOMPATIBILITY COMPLEX M.MANIKANDAN.pptx
Major histocompatility complex (Antigen Presentation to T cells, Autoimmunity...
Major histocompatility complex (Antigen Presentation to T cells, Autoimmunity...
L6.0 Immune recognition molecule (MHC,T cell receptor, T cell epitopes, T cel...
L6.0 Immune recognition molecule (MHC,T cell receptor, T cell epitopes, T cel...
IGNTU-eContent-392458762550-B.Sc-Biotechnology-4-Dr.PrashantKumarSingh-IMMUNO...
IGNTU-eContent-392458762550-B.Sc-Biotechnology-4-Dr.PrashantKumarSingh-IMMUNO...
More from Ömer Aslankan
Pleura Tumors pptx
Pleural tumors are growths that develop in the pleura, the thin layer of tissue that surrounds the lungs and lines the chest cavity. The most common pleural tumors are mesothelioma, which develops from the mesothelium cells of the pleura, and metastatic cancers that spread from other areas such as the breast or lungs. Diagnosis involves imaging tests, biopsy, and pathological examination of any pleural fluid or biopsied tissue.
Arrhythmias (Cardiology /Cardiovascular) .pptx
This document lists various types of cardiac arrhythmias including normal sinus rhythm, sinus bradycardia, sinus arrest or block, sinus tachycardia, sinus arrhythmia, premature atrial contractions, atrial fibrillation, atrial flutter, premature ventricular contractions, ventricular tachycardia, paroxysmal supraventricular tachycardia, ventricular fibrillation, asystole, first-degree heart block, second-degree heart block of Mobitz types I and II, and third-degree heart block.
Diabetes Mellitus Type 1 and Type 2).pptx
Diabetes mellitus is a chronic disease characterized by high blood sugar levels. It occurs when the pancreas does not produce enough insulin or the body cannot effectively use the insulin it produces. There are two main types of diabetes - type 1 diabetes results from the body's failure to produce insulin and requires insulin injections, type 2 diabetes occurs when the body becomes resistant to insulin and is often associated with excess body weight and physical inactivity.
peptic ulcer(gastric, duodenal stress ulcers ppts
This document discusses the impact of COVID-19 on the global economy. It notes that the pandemic has caused widespread disruptions to economic activity and international trade. Major economic effects of the crisis include a slowdown in production and decline in consumption levels across many countries due to lockdowns and social distancing measures put in place to control the spread of the virus.
Pericardial disease.pptx
The document discusses pericardial disease. Pericardial disease refers to conditions that affect the pericardium, which is the sac-like membrane surrounding the heart. Common types of pericardial disease include pericarditis, which is inflammation of the pericardium, and pericardial effusion, which occurs when excess fluid builds up in the pericardial sac.
Melanoma.pptx
This document discusses the different types of melanoma, a serious form of skin cancer that originates from melanocytes. It describes the most common type, superficial spreading melanoma, which makes up around 70% of cases and typically appears as an irregular dark spot on the skin. Less common types include nodular melanoma, which is very aggressive and appears as a raised lesion, lentigo maligna melanoma which appears as a flat dark spot on sun-exposed skin, and acral lentiginous melanoma which affects the palms, soles, and under nails and is most prevalent in darkly pigmented races. The location and appearance of melanoma can vary depending on the specific type and between men and women.
aphasia.pptx
Aphasia is a language disorder caused by damage to the left side of the brain, typically from a stroke or head injury, that impairs a person's ability to communicate. There are different types of aphasia depending on which language abilities are affected, such as Broca's aphasia which impacts speech production or Wernicke's aphasia which affects speech comprehension. Aphasia treatment aims to help patients regain lost language skills or adapt new ways of communicating through speech and language therapy.
pancreas ppt.pptx
The pancreas is a gland located behind the stomach that has both exocrine and endocrine functions. The exocrine part secretes pancreatic juice to aid digestion, while the endocrine part secretes hormones like insulin. It is a soft, lobulated organ about 12-15 cm in length that is surrounded by other organs like the small intestine, liver, and spleen.
epidemiology.pptx
This document discusses epidemiology studies and case-control study designs. It references sources that define case-control studies as observational studies that compare subjects with a specific outcome (cases) to subjects without that outcome (controls) to determine associations between the outcome and prior exposures or risk factors. The sources provide more information on the methodology and use of case-control studies.
Rabies Virus.pptx
Rabies is a fatal viral disease that affects the central nervous system. It is caused by a rhabdovirus that is most commonly transmitted to humans via bites from rabid bats, foxes, skunks, and raccoons in North America, and dogs worldwide. There is no established treatment for rabies once symptoms develop, so prevention through vaccination is important.
Human herpesviruses.pdf
This document summarizes several human herpesviruses:
1) Herpes simplex virus types 1 and 2 which can cause oral and genital lesions respectively and establish latency in nerve ganglia.
2) Varicella zoster virus which causes chickenpox and shingles and establishes latency in neurons.
3) Epstein-Barr virus which infects B cells and causes mononucleosis and some cancers by immortalizing B cells.
4) Cytomegalovirus which establishes latency in mononuclear cells and is a common cause of in utero infection in the US.
communicable disease .pdf
A communicable disease is caused by pathogens that can be transmitted between humans and animals. Common pathogens include viruses, bacteria, and fungi. Communicable diseases spread through various routes such as physical contact, airborne droplets, contaminated fluids or foods, or bites from insects or animals. Factors that influence the transmission of communicable diseases include the infectious agent, the route of exit from the host, the mode of transmission, the route of entry into a new host, and characteristics of the susceptible host. Communicable diseases have historically been a major cause of death but advances in public health have helped reduce their spread.
Diuretics .pdf
This document summarizes different types of diuretic drugs, including their mechanisms of action, indications for use, and potential adverse effects. It discusses 5 main classes of diuretics: 1) acetazolamide, which blocks carbonic anhydrase and decreases water resorption, 2) loop diuretics like furosemide that inhibit the NKCC2 pump and promote high volume diuresis, 3) mannitol, an osmotic diuretic that works in the proximal tubule, 4) thiazide and thiazide-like diuretics that inhibit sodium resorption in the distal tubule, and 5) potassium-sparing diuretics like spironolactone
Antigens and MHC
Antigens are foreign molecules recognized by the immune system that can bind to antigen-specific receptors on antibodies and T cells. An immunogen is an antigen that induces an immune response by binding to B-cell or T-cell receptors, while a hapten is too small on its own but can become immunogenic when attached to a carrier protein. Epitopes are the specific parts of antigens that are recognized by the immune system. Exogenous antigens come from outside the body and endogenous antigens are generated inside cells.
History Taking .pdf
This document provides guidance on performing a comprehensive health history and physical examination. It outlines the key components of the health history, including the present illness, past medical history, family history, social history, and review of systems. It also describes the subjective and objective components. For the physical exam, it recommends examining the patient systematically from head to toe, using appropriate lighting, positioning, and techniques. It emphasizes taking vital signs, performing a general survey, and inspecting each body system. The goal is to obtain relevant health information through the history and physical exam to aid clinical decision making.
Introduction to medical virology.pdf
Viruses are acellular infectious agents that contain nucleic acids surrounded by protein coats. They are obligate parasites that do not carry out metabolism and lack organelles and ribosomes. Viruses come in various structures like helical, icosahedral, enveloped, and more complex forms. They replicate inside host cells by attaching to receptors, penetrating the cell, uncoating their genetic material, synthesizing new viral components, assembling new viral particles, and releasing particles to infect new cells. Viruses are classified into groups based on their nucleic acids, structures, and replication mechanisms. DNA viruses like herpesvirus contain double-stranded DNA and replicate in the nucleus, while RNA viruses have single-stranded genomes
Immune Organs - organs of the immune system and immune cells .pdf
The tissues of the immune system consist of primary and secondary lymphoid organs. Primary organs include the thymus and bone marrow, where T and B cells mature. Secondary organs include the spleen, lymph nodes, and mucosal tissues, where immune cells are activated. Mature T cells proliferate and migrate to sites of infection, while mature B cells give rise to plasma cells and memory B cells upon activation. The immune system tissues work together to recognize pathogens and mount targeted responses through cellular and humoral immunity.
More from Ömer Aslankan (20)
Immune Organs - organs of the immune system and immune cells .pdf
Immune Organs - organs of the immune system and immune cells .pdf
Recently uploaded
The Best Ayurvedic Antacid Tablets in India
Treat the symptoms of indigestion, heartburn and stomach reflux with the 10 Best Ayurvedic Antacid Tablets in India.
Efficacy of Avartana Sneha in Ayurveda
Avartana Sneha is a unique method of Preparation of Sneha Kalpana in Ayurveda, mainly it is indicated for the Vataja rogas.
Clinic ^%[+27633867063*Abortion Pills For Sale In Tembisa Central
Clinic ^%[+27633867063*Abortion Pills For Sale In Tembisa Central Clinic ^%[+27633867063*Abortion Pills For Sale In Tembisa CentralClinic ^%[+27633867063*Abortion Pills For Sale In Tembisa CentralClinic ^%[+27633867063*Abortion Pills For Sale In Tembisa CentralClinic ^%[+27633867063*Abortion Pills For Sale In Tembisa Central
Post-Menstrual Smell- When to Suspect Vaginitis.pptx
Do you have abnormal smell after periods? It may be vaginitis. Do not worry, herbal medicine Fuyan Pill can help you get a cure.
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptx
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptxHolistified Wellness
We’re talking about Vedic Meditation, a form of meditation that has been around for at least 5,000 years. Back then, the people who lived in the Indus Valley, now known as India and Pakistan, practised meditation as a fundamental part of daily life. This knowledge that has given us yoga and Ayurveda, was known as Veda, hence the name Vedic. And though there are some written records, the practice has been passed down verbally from generation to generation.TEST BANK For Community Health Nursing A Canadian Perspective, 5th Edition by...
TEST BANK For Community Health Nursing A Canadian Perspective, 5th Edition by Stamler, Verified Chapters 1 - 33, Complete Newest Version Community Health Nursing A Canadian Perspective, 5th Edition by Stamler, Verified Chapters 1 - 33, Complete Newest Version Community Health Nursing A Canadian Perspective, 5th Edition by Stamler Community Health Nursing A Canadian Perspective, 5th Edition TEST BANK by Stamler Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Pdf Chapters Download Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Pdf Download Stuvia Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Study Guide Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Ebook Download Stuvia Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Questions and Answers Quizlet Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Studocu Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Quizlet Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Stuvia Community Health Nursing A Canadian Perspective, 5th Edition Pdf Chapters Download Community Health Nursing A Canadian Perspective, 5th Edition Pdf Download Course Hero Community Health Nursing A Canadian Perspective, 5th Edition Answers Quizlet Community Health Nursing A Canadian Perspective, 5th Edition Ebook Download Course hero Community Health Nursing A Canadian Perspective, 5th Edition Questions and Answers Community Health Nursing A Canadian Perspective, 5th Edition Studocu Community Health Nursing A Canadian Perspective, 5th Edition Quizlet Community Health Nursing A Canadian Perspective, 5th Edition Stuvia Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Pdf Chapters Download Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Pdf Download Stuvia Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Study Guide Questions and Answers Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Ebook Download Stuvia Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Questions Quizlet Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Studocu Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Quizlet Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Stuvia
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Kat...
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Kat...rightmanforbloodline
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Katzung, Verified Chapters 1 - 66, Complete Newest Version.
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Katzung, Verified Chapters 1 - 66, Complete Newest Version.
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Katzung, Verified Chapters 1 - 66, Complete Newest Version.
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Katzung, Verified Chapters 1 - 66, Complete Newest Version.Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
Artificial Intelligence Symposium (THAIS)
Artificial Intelligence Symposium (THAIS). Parc Taulí. Sabadell
Histololgy of Female Reproductive System.pptx
Dive into an in-depth exploration of the histological structure of female reproductive system with this comprehensive lecture. Presented by Dr. Ayesha Irfan, Assistant Professor of Anatomy, this presentation covers the Gross anatomy and functional histology of the female reproductive organs. Ideal for students, educators, and anyone interested in medical science, this lecture provides clear explanations, detailed diagrams, and valuable insights into female reproductive system. Enhance your knowledge and understanding of this essential aspect of human biology.
The Electrocardiogram - Physiologic Principles
These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Journal Article Review on Rasamanikya
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
Recently uploaded (20)
Vestibulocochlear Nerve by Dr. Rabia Inam Gandapore.pptx
Vestibulocochlear Nerve by Dr. Rabia Inam Gandapore.pptx
CHEMOTHERAPY_RDP_CHAPTER 6_Anti Malarial Drugs.pdf
CHEMOTHERAPY_RDP_CHAPTER 6_Anti Malarial Drugs.pdf
Clinic ^%[+27633867063*Abortion Pills For Sale In Tembisa Central
Clinic ^%[+27633867063*Abortion Pills For Sale In Tembisa Central
Post-Menstrual Smell- When to Suspect Vaginitis.pptx
Post-Menstrual Smell- When to Suspect Vaginitis.pptx
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptx
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptx
TEST BANK For Community Health Nursing A Canadian Perspective, 5th Edition by...
TEST BANK For Community Health Nursing A Canadian Perspective, 5th Edition by...
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Kat...
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Kat...
Muscles of Mastication by Dr. Rabia Inam Gandapore.pptx
Muscles of Mastication by Dr. Rabia Inam Gandapore.pptx
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...
MHC.pptx
- 1. MAJOR HISTOCOMPATIBILITY COMPLEX (MHC) By; Omer ASLANKAN
- 2. INTRODUCTİON • Major Histocompactibility complex (MHC) is set of surface proteins located on the cell membrane of nucleated cells. • It plays more important work to indentify the antigen between self and non self body, intracellular recognization and responsible for antigen presentation. • Histo refers to tissues. Compatibility refers to living together harmoniously. • MHC molecules always recognize only T lymphocytes. • The two types of MHC are worked in immunity. • T helper (Th) cell recognized by MHC molecules II. • T cytotoxic (Tc) cells are recognized by MHC I molecules.
- 4. CLASS I MHC MOLECULES • Class I MHC molecule are a group of major histocompactibility antigen. • They are present on the surface of all nucleated cells except nervous tissue and platelets. • It present antigen to Tc cells. • It bind with CD-8 adhesion molecules of Te cells. • It brings about cell mediated immune response. • It found on all nucleated cells.
- 5. STRUCTURE OF CLASS I MHC MOLECULE • It consists two polypeptide chains namely a chain and B2 - micro globulin. • a chain which is non covalently attached with B2 microglobuline . • a chain contain a transmembrane glycoprotein which is encoded by A,B and C gene of grouped HLA. (Human leukocyte antigens (HLA; are proteins—or markers—on most cells in body) • a chain is organized by three domains such as a 1, a 2 and a 3 each domain containing 90 amino acids sequences . • B2 microglobuline is similar in size of a 3 and it dose not contain trans membrane proteins . • When the antigen is internalized and processed inside by proteosome (Ubiquitin, cytosolic degradation), the peptides are produced . • Peptide is further loaded on the groove of MHC I molecules from endoplasmicreticulum.
- 6. CLASS II MHC MOLECULE • Class II MHC molecule are present on the surface of antigen presenting cell and cell which engulfed the foreign antigen. • It binds with the exogenous(endocytic degradation ) antigens. • It binds with CD4 adhesion molecules Th cells. • It also consist of two polypeptide chains namely a chain and B chain. • Antigen is processed inside the endosome and peptide is further loaded on groove of MHC II molecules. • It found only on APCs
- 7. STRUCTURE OF MHC II MOLECULE • The class II MHC Molecule consists of two polypeptide chain namely a chain and B chain. • The both chain are attached noncovelantly. • Each chain contains two units. • The two units of a chain are called al and a2. • The two domains of B chains are called B1 and B2. • B2 and a2 are transmembrane domains anchoring the MHC to plasma membrane. • The al and B1 domains jointly bear a peptide binding groove.
- 9. FUNCTION OF MHC MOLECULES • MHC molecules are loaded with a bit of sample peptide fragment derived from the degradation of proteins present inside the cell. This peptide is the mirror image of proteins present inside the cell. • MHC molecules contain self as well as nonself (foreign) antigen. • They bring about defense against infections and diseases. • They mediate certain autoimmune diseases. • They are responsible for individual smell of people.
- 10. DIFFERENCES BETWEEN MHC CLASS I & CLASS II
- 11. SIMILARITIES BETWEEN MHC CLASS I & MHC CLASS II
- 12. REFERENCES • https://www.ncbi.nlm.nih.gov/books/NBK546662/#:~:text=Human% 20leukocyte%20antigens%20(HLA)%20are,can%20also%20have%20 detrimental%20effects. • https://youtu.be/t81EjpkCiss • https://quizlet.com/3489839/mhc-i-and-ii-flash-cards/ • https://www.slideshare.net/Prasannjeetsaha/major-histocompatibility- complex-78885656 • https://www.slideshare.net/AbhijitDebnath143/structure-and-function- of-mhc