A communicable disease is caused by pathogens that can be transmitted between humans and animals. Common pathogens include viruses, bacteria, and fungi. Communicable diseases spread through various routes such as physical contact, airborne droplets, contaminated fluids or foods, or bites from insects or animals. Factors that influence the transmission of communicable diseases include the infectious agent, the route of exit from the host, the mode of transmission, the route of entry into a new host, and characteristics of the susceptible host. Communicable diseases have historically been a major cause of death but advances in public health have helped reduce their spread.