15% of school children have chronic health conditions that can impact learning. Conditions like sickle cell disease cause pain episodes preceded by infections, dehydration or imbalances. Mild episodes can be managed with medication at school, but severe episodes require staying home or hospitalization. It is important that parents and teachers communicate about students' medical needs and allow flexibility for absences due to pain without doctor's notes. Maintaining hydration and allowing breaks can help prevent sickle cell crises. Individualized healthcare plans are important to support students with chronic conditions in regular classrooms.