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Clinical Observation of ORIF of Condylar
Intracapsular Fracture assisted by Local
Medicinal Chitosan
Under the Guidance of :-
Prof. (Dr.) Li Xiang Jun
Dr.Sun Xu
Presented By:-
Dr.Anas Ameer Khan
1 Introduction to TMJ
2 Movements by TMJ
5
Condylar Fracture
3
Signs & Symptoms
CONTENTS
6
7
Treatment
Medicinal Chitosan
8
A Comparative Study
4 The Conclusion
Introduction to TMJ
The temporomandibular joint (TMJ), or jaw
joint, is a synovial joint that allows the
complex movements necessary for life. It is
the joint between condylar head of the
mandible and the mandibular fossa of the
temporal bone. This system is made up of the
TMJ.
The complex movements of TMJ allow multiple functions:
 Chewing
 Sucking
 Swallowing
 Phonation
 Facial expressions
 Opening the mouth
 To maintain the correct
pressure of the middle
ear.
 Breathing
 Protrusion
 Retrusion
 Lateralization of the jaw
These movements are constrained by various passive factors, as well as passive tension
of the ligaments and muscles.
Dysfunction of the TMJ can cause severe pain and lifestyle limitation.
Facial Expressions Movements
Movements of TMJ
Condylar Fracture
Signs & Symptoms
Swelling over TMJ region.
Bleeding from the ear.
Restricted and painful jaw movement.
Gagging of the teeth on the fractured side.
Shortening of the height of the ramus.
Hematoma can be seen downwards and backwards of the ear.
Open Bite becomes progressively worse to the unaffected side.
Treatment
1-Reduction
2-Fixation
Open
Reduction
Closed
Reduction
Open
Fixation
Closed
Fixation
Fixation
Open Fixation Closed Fixation
Medicinal Chitosan
 Chitosan is a naturally occurring marine polysaccharide fiber derived
from a common byproduct of shellfish (crustaceans) processing.
 Chitosan is a safe and reliable polysaccharide polymer
with excellent biocompatibility,degradability and
biological activity.
 It is often used to prevent tissue adhesions
after surgery and has been used in the
conservative treatment of osteoarthropathy.
03
01
02
The Therapeutic Effects
of Chitosan Injection
03
02
01 04
It inhibits the proliferation
of fibroblasts.
Reduces scar hyperplasia
after operation,and avoids
the occurrence of adhesion.
Based on its ability to
cross the cartilage surface,
it acts as a mechanical
barrier that inhibits the
release of inflammatory
factors, which relieves
pain.
It promotes the
synthesis of cartilage
extracellular matrix
to regulate the
metabolism of
chondrocytes.
As a viscoelastic supplement,
it reduces the fluidity of joint
synovial fluid to help lubricate
joints.
A Comparative
Case Study
 10 Patients with Condyle Fracture
 Open Reduction & Fixation
 Only Postpartum Routine Training
 Curative Effect Measured
 Pain Score Measured
 Joint Bounce Measured
 Degree of Mouth Opening Measured
Control Group
 10 Patients with Condyle Fracture
 Open Reduction & Fixation
 PRT + Inj.Chitosan 1st,2nd,3rd&4th W.
 Curative Effect Measured
 Pain Score Measured
 Joint Bounce Measured
 Degree of Mouth Opening Measured
Observation Group
Objective:
To investigate the clinical effect of reposition and fixation of condylar intracapsular fracture
assisted by intra-articular injection of medicinal chitosan
Preoperative CBCT Imaging of Condylar
Intracapsular Fracture
Postoperative CBCT Imaging of Condylar
Intracapsular Fracture
Pre & Post Surgical CBCT
& Photographs
Results on Clinical Efficacies,
Pain Score & Joint Bounce
Group
Efficiency
(%)
Pain Score
(%)
Joint
Bounce
(%)
Control Group 70.68 2.710.74 23.16
Observation
Group
89.96 1.620.53 8.78
P Value P<0.05 P<0.05 P<0.05
Results on Mouth
Opening
Group 1st Week
(cm)
2nd Week
(cm)
3rd Week
(cm)
4th Week
(cm)
Control
Group
1.380.43 1.420.33 1.870.62 2.260.73
Observation
Group
1.510.25 1.880.17 2.350.56 2.980.44
P value P>0.05 P<0.05 P<0.05 P<0.05
Pre & Post Surgical Mouth
Opening Photographs
Observation Group Control Group
One week after Surgery
Two week after Surgery
Three week after Surgery
Four week after Surgery
Observation Group Control Group
The Conclusion
01
Intra articular injection of medical chitosan after open reduction and internal
fixation of intracapsular condylar fracture can reduce postoperative pain,
bounce and promote the functional recovery.
02
It shows better clinical effects compared with traditional conservative
treatment.
03
Hence,we hypothesize that surgery combined with postoperative
chitosan injection is effective in the treatment of TMJOA and
感 谢 聆 听 , 有 美 好 的 一 天
In the end, success finds those who struggle to get it.
“ My Dad”

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Medicinal Chitosan in Condylar Fracture .pptx

  • 1. Clinical Observation of ORIF of Condylar Intracapsular Fracture assisted by Local Medicinal Chitosan Under the Guidance of :- Prof. (Dr.) Li Xiang Jun Dr.Sun Xu Presented By:- Dr.Anas Ameer Khan
  • 2. 1 Introduction to TMJ 2 Movements by TMJ 5 Condylar Fracture 3 Signs & Symptoms CONTENTS 6 7 Treatment Medicinal Chitosan 8 A Comparative Study 4 The Conclusion
  • 3. Introduction to TMJ The temporomandibular joint (TMJ), or jaw joint, is a synovial joint that allows the complex movements necessary for life. It is the joint between condylar head of the mandible and the mandibular fossa of the temporal bone. This system is made up of the TMJ.
  • 4. The complex movements of TMJ allow multiple functions:  Chewing  Sucking  Swallowing  Phonation  Facial expressions  Opening the mouth  To maintain the correct pressure of the middle ear.  Breathing  Protrusion  Retrusion  Lateralization of the jaw These movements are constrained by various passive factors, as well as passive tension of the ligaments and muscles. Dysfunction of the TMJ can cause severe pain and lifestyle limitation.
  • 8. Signs & Symptoms Swelling over TMJ region. Bleeding from the ear. Restricted and painful jaw movement. Gagging of the teeth on the fractured side. Shortening of the height of the ramus. Hematoma can be seen downwards and backwards of the ear. Open Bite becomes progressively worse to the unaffected side.
  • 11. Medicinal Chitosan  Chitosan is a naturally occurring marine polysaccharide fiber derived from a common byproduct of shellfish (crustaceans) processing.  Chitosan is a safe and reliable polysaccharide polymer with excellent biocompatibility,degradability and biological activity.  It is often used to prevent tissue adhesions after surgery and has been used in the conservative treatment of osteoarthropathy. 03 01 02
  • 12. The Therapeutic Effects of Chitosan Injection 03 02 01 04 It inhibits the proliferation of fibroblasts. Reduces scar hyperplasia after operation,and avoids the occurrence of adhesion. Based on its ability to cross the cartilage surface, it acts as a mechanical barrier that inhibits the release of inflammatory factors, which relieves pain. It promotes the synthesis of cartilage extracellular matrix to regulate the metabolism of chondrocytes. As a viscoelastic supplement, it reduces the fluidity of joint synovial fluid to help lubricate joints.
  • 13. A Comparative Case Study  10 Patients with Condyle Fracture  Open Reduction & Fixation  Only Postpartum Routine Training  Curative Effect Measured  Pain Score Measured  Joint Bounce Measured  Degree of Mouth Opening Measured Control Group  10 Patients with Condyle Fracture  Open Reduction & Fixation  PRT + Inj.Chitosan 1st,2nd,3rd&4th W.  Curative Effect Measured  Pain Score Measured  Joint Bounce Measured  Degree of Mouth Opening Measured Observation Group Objective: To investigate the clinical effect of reposition and fixation of condylar intracapsular fracture assisted by intra-articular injection of medicinal chitosan
  • 14. Preoperative CBCT Imaging of Condylar Intracapsular Fracture Postoperative CBCT Imaging of Condylar Intracapsular Fracture Pre & Post Surgical CBCT & Photographs
  • 15. Results on Clinical Efficacies, Pain Score & Joint Bounce Group Efficiency (%) Pain Score (%) Joint Bounce (%) Control Group 70.68 2.710.74 23.16 Observation Group 89.96 1.620.53 8.78 P Value P<0.05 P<0.05 P<0.05
  • 16. Results on Mouth Opening Group 1st Week (cm) 2nd Week (cm) 3rd Week (cm) 4th Week (cm) Control Group 1.380.43 1.420.33 1.870.62 2.260.73 Observation Group 1.510.25 1.880.17 2.350.56 2.980.44 P value P>0.05 P<0.05 P<0.05 P<0.05
  • 17. Pre & Post Surgical Mouth Opening Photographs Observation Group Control Group One week after Surgery Two week after Surgery Three week after Surgery Four week after Surgery Observation Group Control Group
  • 18. The Conclusion 01 Intra articular injection of medical chitosan after open reduction and internal fixation of intracapsular condylar fracture can reduce postoperative pain, bounce and promote the functional recovery. 02 It shows better clinical effects compared with traditional conservative treatment. 03 Hence,we hypothesize that surgery combined with postoperative chitosan injection is effective in the treatment of TMJOA and
  • 19. 感 谢 聆 听 , 有 美 好 的 一 天 In the end, success finds those who struggle to get it. “ My Dad”