This document provides a summary of the history of MDMA from its discovery and early uses in psychotherapy to its prohibition and rise in recreational use. Some key points:
- MDMA was first synthesized in 1912 and studied by the US Army for potential use in chemical warfare in the 1950s. Psychotherapist Leo Zeff popularized its use in therapy in the 1970s, calling it "Adam".
- MDMA gained popularity in psychotherapy in the 1980s but its recreational use also increased, especially in the rave scene. Catholic priest Michael Clegg popularized the name "Ecstasy".
- The DEA banned MDMA in 1985 despite protests from therapists about its benefits. Its legal status fluctuated but
The document summarizes the use of social media during disaster events. It discusses how social media is used for collaboration, expressing gratitude and grief, and sharing experiences during crises. It provides examples of how government agencies and organizations used social media before and after Hurricane Sandy to plan, respond to, and recover from the storm through information sharing and situational awareness. Key metrics on social media mentions and photos related to Sandy are presented to demonstrate the scale of engagement on platforms like Twitter, Facebook, Instagram and Foursquare. The importance of verifying information before sharing on social media is emphasized.
Larsen Manufacturing is a precision metal manufacturing company that has been in business for over 70 years. They provide services like metal stamping, fabrication, machining and PCB depaneling. The document discusses Larsen's history and growth, leadership, capabilities across various manufacturing processes, and emphasis on quality, value engineering and customer satisfaction. It also includes examples of products they have manufactured for various industries.
Three simple ways you can improve any business with IBM ConnectionsLetsConnect
Many organisations think productivity and communications gains come simply by making an enterprise social network available to their users. The truth is you must find a genuine purpose for the system for it to be adopted and grow. Join this session to explore three simple uses you can put IBM Connections to in your business which will drive productivity, community and improve communications. Based on real-life implementations, Alan will show you how you can get started today.
Projects Department Weekly Report - SVC Hail-2, Dynamic and Static React.... ...ATIF HUSSAIN
This weekly progress report provides an update on the Dynamic Reactive Power Compensation project at the Hail-2 and Al-Jouf-2 380kV substations in Saudi Arabia. The key points are:
1) The project involves installing +450MVAr (capacitive) and -150MVAr (inductive) 380kV SVC systems at Hail-2 to improve rapid voltage support.
2) Major milestones for the SVC at Hail-2 include technical completion on June 2, 2016, preliminary acceptance on August 2, 2016, and final acceptance on November 2, 2016.
3) Commissioning of the SVC at Al-Jouf-2 is 98
This document provides a list of 47 items authored or edited by Colin Gagg related to forensic engineering and failure analysis. These include authored books, book chapters, journal articles, conference papers, and public lectures on topics such as failure of materials, products, structures, and case studies in forensic engineering.
The document summarizes the use of social media during disaster events. It discusses how social media is used for collaboration, expressing gratitude and grief, and sharing experiences during crises. It provides examples of how government agencies and organizations used social media before and after Hurricane Sandy to plan, respond to, and recover from the storm through information sharing and situational awareness. Key metrics on social media mentions and photos related to Sandy are presented to demonstrate the scale of engagement on platforms like Twitter, Facebook, Instagram and Foursquare. The importance of verifying information before sharing on social media is emphasized.
Larsen Manufacturing is a precision metal manufacturing company that has been in business for over 70 years. They provide services like metal stamping, fabrication, machining and PCB depaneling. The document discusses Larsen's history and growth, leadership, capabilities across various manufacturing processes, and emphasis on quality, value engineering and customer satisfaction. It also includes examples of products they have manufactured for various industries.
Three simple ways you can improve any business with IBM ConnectionsLetsConnect
Many organisations think productivity and communications gains come simply by making an enterprise social network available to their users. The truth is you must find a genuine purpose for the system for it to be adopted and grow. Join this session to explore three simple uses you can put IBM Connections to in your business which will drive productivity, community and improve communications. Based on real-life implementations, Alan will show you how you can get started today.
Projects Department Weekly Report - SVC Hail-2, Dynamic and Static React.... ...ATIF HUSSAIN
This weekly progress report provides an update on the Dynamic Reactive Power Compensation project at the Hail-2 and Al-Jouf-2 380kV substations in Saudi Arabia. The key points are:
1) The project involves installing +450MVAr (capacitive) and -150MVAr (inductive) 380kV SVC systems at Hail-2 to improve rapid voltage support.
2) Major milestones for the SVC at Hail-2 include technical completion on June 2, 2016, preliminary acceptance on August 2, 2016, and final acceptance on November 2, 2016.
3) Commissioning of the SVC at Al-Jouf-2 is 98
This document provides a list of 47 items authored or edited by Colin Gagg related to forensic engineering and failure analysis. These include authored books, book chapters, journal articles, conference papers, and public lectures on topics such as failure of materials, products, structures, and case studies in forensic engineering.
Definir un objetivo puede ser, muchas veces, el punto de quiebre para que un plan se lleve a cabo de la manera más eficiente. Es decir, el paso a la acción directa establecida en un intervalo de tiempo.
This document appears to be a dissertation submitted by Rahul Donga to Gujarat Technological University in partial fulfillment of a Bachelor of Engineering degree. It was developed by Rahul Donga at J.B. Electronics and LDRP Institute of Technology and Research in Gandhinagar, India. The dissertation discusses programmable logic controllers, including their components, programming, and applications.
El documento describe la importancia de los valores en una compañía y cómo estos representan la forma de trabajar. Los valores expresan cómo debe trabajar cada empleado y establecen los límites para alcanzar la visión de la compañía. Al definir valores como el respeto, el trabajo en equipo o la integridad, se fideliza al personal y se crea una cultura empresarial positiva. Los valores también dan a la compañía una identidad frente a los clientes y el mercado.
Costruire il proprio profilo su linkedIN (ITALIANO)Andrea Cattaneo
Crea un profilo efficace
Cosa fare prima, dopo e durante la scrittura di un profilo:
Premesse & preparazione: Perché fare il profilo LinkedIN e il TUO “materiale”.
Compilazione : Le varie parti del profilo.
Pubblicazione : Metti “on-line” il TUO profilo e diventa “social” su LinkedIN.
Grazie alle mie correttrici: Moira Zugno, Daniela Bommarito e Paola Cottino.
The soil system is a dynamic ecosystem with inputs, outputs, storages and flows. The quality of soil influences the primary productivity of an area. Soil is made up of organic matter, organisms, nutrients, minerals, air and water. It exists in solid, liquid and gas states. Soils take a long time to develop and are considered a non-renewable resource. Soil degradation reduces soil quality and can be caused by erosion, biological degradation, physical degradation and chemical degradation from human activities like agriculture. Conservation efforts aim to reduce erosion, improve soil structure and condition, and promote sustainable land management.
The Urban Management Centre is a notforprofit organization based in Ahmedabad, Gujarat, working towards professionalizing urban management in India and South Asia. UMC provides technical assistance and support to Indian state local government associations and implements programs that work towards improvement in cities by partnering with city governments. UMC builds and enhances the capacity of city governments by providing muchneeded expertise and ready access to innovations on good governance implemented in India and abroad. UMC is a legacy organization of International City/County Management Association (ICMA) and hence is also known as ICMASouth Asia.
Office: Municipal Central Workshop Compound,
Opp. Sahakari Lati Bazar, Jagannathji Road, Ahmedabad- 380 022
Telephone No. 079-32982385 Fax No. 079-25321484
E-mail: swm@egovamc.com
We created an Advertising campaign for class about the popular cheesy snack Cheez Doodles. My team, Top Tier Ad Agency, played up the "cheez" factor of "Cheez Doodles" with a 90's nostalgic marketing approach, utilizing popular television shows, specifically on Nickelodeon, to target Millennials and their childhood. We also implemented an immersive and integrated marketing experience with Out-Of-Home executions that would surely attract attention from Millennials.
environmental control of poultry farms PLC based project reportAhsan Naeem Chaudary
This document outlines a study to develop and implement an environmental control system for poultry farms. The system will sense and control three key parameters: temperature, water level, and humidity. Sensors will monitor the parameters and a programmable logic controller (PLC) will correct any deviations from required conditions to ensure a healthy environment for chicken growth. The project aims to provide full understanding and control of the farm's environmental conditions. A literature review covers PLC programming and common temperature, humidity, and water level sensors.
To achieve sustainable agricultural production it is imperative to explore alternative integrated soil and nutrient management systems with minimum environmental degradation. Integrated Nutrient Management (INM) aims at maintenance or adjustment of soil fertility and plant nutrient supply to an optimum level for sustaining the desired crop productivity through optimization of benefit from all possible sources of plant nutrients in an integrated manner (Roy and Ange, 1991). Continuous and imbalanced use of fertilizers under intensive agricultural cultivation had adverse impact on the soil. Use of bio and organic fertilizers and adherence to ecofriendly land management practice enhances crop production and sustains soil fertility (Sailaja and Usha, 2002). Keeping these in view, INM practice is seen as a viable option in restoring the soil physical structure and chemical fertility, improving soil organic C and therefore, sustaining the system productivity. Sources such as nitrogen fixers, phosphate solubilizers, mycorrhize and other beneficial organisms contribute to enhance efficient uptake of plant nutrients (Gupta et al., 2003).
INM tries to reduce the need for chemical fertilizers by taking advantages of non-chemical sources of nutrients such as the manures, composts and bio-fertilizers (Gopalasundaram et al., 2012). Bio-fertilizers application not only increases plants growth and yield, but increase soil microbial population and activity; resulting in improved soil fertility (Ramesh et al., 2014). They include free-living bacteria which promote plant growth even in polluted soils. Azospirillum, Azotobacter, Pseudomonas, Bacillus and Thiobacillus are examples of these bacteria (Zahir et al., 2004). Niess (2002) reported that plant growth promoting bacteria reduced the toxicity of heavy metals and increased plant growth and yield.
Apart from this, agroforestry interventions through integration of suitable trees, soil improvement through cover cropping, soil and water conservation measures etc can be potential INM strategies that can be practiced to sustain yield, minimize risk, utilize the lag phase, and improve productivity (Rao, 2000). The success of INM depends on the judicious use of the right combination of INM component suitable for a particular land use system.
Diseño Instruccional Y Tic Basado En Blo Gsguestf5edca
Presentación que muestra esquemáicamente relación entre Diseño Instruccional y TIC basado en BLOGs. Adaptación, realizada por Ricardo Vásquez, de presentación "modelo-de-diseo-instruccional-basado-en-weblogs223" cuyo autor es José Antonio Rivas Chirinos.
Mahmoud Yacoub is an electrical engineer with over 6 years of experience working on high voltage projects in Saudi Arabia. He is currently a technical advisor and lead installation supervisor at ABB Electrical Industries Company in Saudi Arabia, where he is responsible for full gas insulated switchgear (GIS) substation projects from planning to testing and handover. He has successfully completed three major GIS substation projects in Saudi Arabia involving voltages up to 550kV. Yacoub is certified as a GIS supervisor by ABB Switzerland and aims to continue gaining experience in new technologies.
This document describes an online library management system created by Bharat Raj Kunwar. The system allows librarians and students to manage library activities and resources digitally. Main features include allowing users to search for and request books, and for librarians to add, remove, and edit user and book details. The system was created using PHP, HTML, CSS for the front end and MySQL for the back end database. Testing was conducted and future improvements like online reading capabilities are discussed. In conclusion, the system aims to digitize key library functions to make managing and accessing resources more convenient.
This document provides an introduction and overview of forests in India. It defines forests and describes different classification systems for forests based on factors like age, growing stock, and species composition. It then outlines the major forest types in India according to the Champion and Seth classification system from 1935, including tropical wet evergreen forests, tropical moist deciduous forests, tropical dry deciduous forests, and various Himalayan forest types. It concludes by discussing the importance and distribution of forests in India, as well as some problems related to forest development.
This document defines agroforestry as a sustainable land use system that combines trees, crops, and livestock. It discusses several types of agroforestry including silvopasture, alley cropping, forest farming, riparian forest buffers, and windbreaks/shelterbelts. Silvopasture combines trees, forage, and livestock. Alley cropping grows crops between rows of trees. Forest farming cultivates high-value crops under forest canopy. Riparian buffers protect waterways. Windbreaks shelter crops, livestock, and roads from wind.
El Test de Bender evalúa la madurez de la percepción visomotriz en niños de 5 a 10 años mediante la copia de 9 figuras geométricas. Se basa en la teoría de la Gestalt y puede detectar problemas en el aprendizaje o desarrollo. Consiste en 30 ítems que miden errores como distorsión de formas, perseverancia e integración. Una puntuación alta indica un bajo rendimiento en percepción visomotriz.
Ecstasy, also known as MDMA, is a synthetic psychoactive drug that alters mood and perception. It was first patented in 1913 but later banned in 1985 due to its negative health effects. While it produces feelings of euphoria and intimacy, it can also cause physical issues like increased heart rate and psychological problems such as depression and anxiety. Long-term use has been linked to brain damage and other serious health problems. Ecstasy remains illegal but is still used recreationally, especially at clubs and music events.
The document provides information on MDMA (Ecstasy/Molly) including its discovery, history of use, effects, and legal status. It was first synthesized in 1912 as a substance to stop abnormal bleeding but research was suspended. In the 1970s, chemist Alexander Shulgin rediscovered its psychoactive effects and published reports of its use. Psychotherapists began experimenting with MDMA to help patients, believing it created "primordial innocence". Throughout the 1980s, MDMA spread widely and was produced on a large scale before being made illegal and classified as a Schedule 1 drug in 1985 due to its abuse potential and lack of accepted medical use.
Ecstasy is a dangerous drug that can have serious short-term and long-term health effects. While it is often portrayed as a "love drug" that enhances sensations, in reality it contains hallucinogenic substances that can cause scary experiences and psychological problems. The document discusses the physical health risks of taking Ecstasy such as dehydration, exhaustion, liver and kidney damage, and even death. It also notes the potential for psychological addiction and that users often move on to other harder drugs to cope with the negative effects. Overall, the document aims to provide facts about Ecstasy and discourage its use by highlighting the very real health dangers.
The document provides an overview of the four main classes of hallucinogenic drugs: serotonergic hallucinogens like LSD and psilocybin; methylated amphetamines like MDMA; anticholinergic hallucinogens found in plants; and dissociative anesthetics like PCP. It discusses the history of hallucinogen use from the 1960s counterculture movement to current trends, physiological and psychological effects of different classes of drugs, risks and adverse effects, and mechanisms of action in the brain.
Psychedlics & applications in PTSD treatment Hayley Peerless
This document summarizes research on the potential applications of psychedelic drugs like MDMA and psilocybin in treating anxiety disorders such as PTSD. It discusses studies that found psychedelic-assisted psychotherapy using these drugs showed promise in reducing symptoms of PTSD and depression in participants. For example, a study on MDMA-assisted therapy found one participant, Nicholas Blackston, had a realization about self-healing during a session. The document also reviews research on the mechanisms of action, risks, and legal status of psychedelics. It calls for further research with larger and more diverse cohorts and different treatment timelines.
MDMA, also known as ecstasy, can induce feelings of intimacy and reduce anxiety. While it has potential therapeutic benefits, it also has dangerous side effects. A study found that MDMA-assisted psychotherapy significantly reduced symptoms of PTSD in patients who had not benefited from other treatments. However, MDMA use carries risks of overdose and long-term neurotoxicity. More research is still needed to fully understand the risks and potential medical applications of MDMA.
Definir un objetivo puede ser, muchas veces, el punto de quiebre para que un plan se lleve a cabo de la manera más eficiente. Es decir, el paso a la acción directa establecida en un intervalo de tiempo.
This document appears to be a dissertation submitted by Rahul Donga to Gujarat Technological University in partial fulfillment of a Bachelor of Engineering degree. It was developed by Rahul Donga at J.B. Electronics and LDRP Institute of Technology and Research in Gandhinagar, India. The dissertation discusses programmable logic controllers, including their components, programming, and applications.
El documento describe la importancia de los valores en una compañía y cómo estos representan la forma de trabajar. Los valores expresan cómo debe trabajar cada empleado y establecen los límites para alcanzar la visión de la compañía. Al definir valores como el respeto, el trabajo en equipo o la integridad, se fideliza al personal y se crea una cultura empresarial positiva. Los valores también dan a la compañía una identidad frente a los clientes y el mercado.
Costruire il proprio profilo su linkedIN (ITALIANO)Andrea Cattaneo
Crea un profilo efficace
Cosa fare prima, dopo e durante la scrittura di un profilo:
Premesse & preparazione: Perché fare il profilo LinkedIN e il TUO “materiale”.
Compilazione : Le varie parti del profilo.
Pubblicazione : Metti “on-line” il TUO profilo e diventa “social” su LinkedIN.
Grazie alle mie correttrici: Moira Zugno, Daniela Bommarito e Paola Cottino.
The soil system is a dynamic ecosystem with inputs, outputs, storages and flows. The quality of soil influences the primary productivity of an area. Soil is made up of organic matter, organisms, nutrients, minerals, air and water. It exists in solid, liquid and gas states. Soils take a long time to develop and are considered a non-renewable resource. Soil degradation reduces soil quality and can be caused by erosion, biological degradation, physical degradation and chemical degradation from human activities like agriculture. Conservation efforts aim to reduce erosion, improve soil structure and condition, and promote sustainable land management.
The Urban Management Centre is a notforprofit organization based in Ahmedabad, Gujarat, working towards professionalizing urban management in India and South Asia. UMC provides technical assistance and support to Indian state local government associations and implements programs that work towards improvement in cities by partnering with city governments. UMC builds and enhances the capacity of city governments by providing muchneeded expertise and ready access to innovations on good governance implemented in India and abroad. UMC is a legacy organization of International City/County Management Association (ICMA) and hence is also known as ICMASouth Asia.
Office: Municipal Central Workshop Compound,
Opp. Sahakari Lati Bazar, Jagannathji Road, Ahmedabad- 380 022
Telephone No. 079-32982385 Fax No. 079-25321484
E-mail: swm@egovamc.com
We created an Advertising campaign for class about the popular cheesy snack Cheez Doodles. My team, Top Tier Ad Agency, played up the "cheez" factor of "Cheez Doodles" with a 90's nostalgic marketing approach, utilizing popular television shows, specifically on Nickelodeon, to target Millennials and their childhood. We also implemented an immersive and integrated marketing experience with Out-Of-Home executions that would surely attract attention from Millennials.
environmental control of poultry farms PLC based project reportAhsan Naeem Chaudary
This document outlines a study to develop and implement an environmental control system for poultry farms. The system will sense and control three key parameters: temperature, water level, and humidity. Sensors will monitor the parameters and a programmable logic controller (PLC) will correct any deviations from required conditions to ensure a healthy environment for chicken growth. The project aims to provide full understanding and control of the farm's environmental conditions. A literature review covers PLC programming and common temperature, humidity, and water level sensors.
To achieve sustainable agricultural production it is imperative to explore alternative integrated soil and nutrient management systems with minimum environmental degradation. Integrated Nutrient Management (INM) aims at maintenance or adjustment of soil fertility and plant nutrient supply to an optimum level for sustaining the desired crop productivity through optimization of benefit from all possible sources of plant nutrients in an integrated manner (Roy and Ange, 1991). Continuous and imbalanced use of fertilizers under intensive agricultural cultivation had adverse impact on the soil. Use of bio and organic fertilizers and adherence to ecofriendly land management practice enhances crop production and sustains soil fertility (Sailaja and Usha, 2002). Keeping these in view, INM practice is seen as a viable option in restoring the soil physical structure and chemical fertility, improving soil organic C and therefore, sustaining the system productivity. Sources such as nitrogen fixers, phosphate solubilizers, mycorrhize and other beneficial organisms contribute to enhance efficient uptake of plant nutrients (Gupta et al., 2003).
INM tries to reduce the need for chemical fertilizers by taking advantages of non-chemical sources of nutrients such as the manures, composts and bio-fertilizers (Gopalasundaram et al., 2012). Bio-fertilizers application not only increases plants growth and yield, but increase soil microbial population and activity; resulting in improved soil fertility (Ramesh et al., 2014). They include free-living bacteria which promote plant growth even in polluted soils. Azospirillum, Azotobacter, Pseudomonas, Bacillus and Thiobacillus are examples of these bacteria (Zahir et al., 2004). Niess (2002) reported that plant growth promoting bacteria reduced the toxicity of heavy metals and increased plant growth and yield.
Apart from this, agroforestry interventions through integration of suitable trees, soil improvement through cover cropping, soil and water conservation measures etc can be potential INM strategies that can be practiced to sustain yield, minimize risk, utilize the lag phase, and improve productivity (Rao, 2000). The success of INM depends on the judicious use of the right combination of INM component suitable for a particular land use system.
Diseño Instruccional Y Tic Basado En Blo Gsguestf5edca
Presentación que muestra esquemáicamente relación entre Diseño Instruccional y TIC basado en BLOGs. Adaptación, realizada por Ricardo Vásquez, de presentación "modelo-de-diseo-instruccional-basado-en-weblogs223" cuyo autor es José Antonio Rivas Chirinos.
Mahmoud Yacoub is an electrical engineer with over 6 years of experience working on high voltage projects in Saudi Arabia. He is currently a technical advisor and lead installation supervisor at ABB Electrical Industries Company in Saudi Arabia, where he is responsible for full gas insulated switchgear (GIS) substation projects from planning to testing and handover. He has successfully completed three major GIS substation projects in Saudi Arabia involving voltages up to 550kV. Yacoub is certified as a GIS supervisor by ABB Switzerland and aims to continue gaining experience in new technologies.
This document describes an online library management system created by Bharat Raj Kunwar. The system allows librarians and students to manage library activities and resources digitally. Main features include allowing users to search for and request books, and for librarians to add, remove, and edit user and book details. The system was created using PHP, HTML, CSS for the front end and MySQL for the back end database. Testing was conducted and future improvements like online reading capabilities are discussed. In conclusion, the system aims to digitize key library functions to make managing and accessing resources more convenient.
This document provides an introduction and overview of forests in India. It defines forests and describes different classification systems for forests based on factors like age, growing stock, and species composition. It then outlines the major forest types in India according to the Champion and Seth classification system from 1935, including tropical wet evergreen forests, tropical moist deciduous forests, tropical dry deciduous forests, and various Himalayan forest types. It concludes by discussing the importance and distribution of forests in India, as well as some problems related to forest development.
This document defines agroforestry as a sustainable land use system that combines trees, crops, and livestock. It discusses several types of agroforestry including silvopasture, alley cropping, forest farming, riparian forest buffers, and windbreaks/shelterbelts. Silvopasture combines trees, forage, and livestock. Alley cropping grows crops between rows of trees. Forest farming cultivates high-value crops under forest canopy. Riparian buffers protect waterways. Windbreaks shelter crops, livestock, and roads from wind.
El Test de Bender evalúa la madurez de la percepción visomotriz en niños de 5 a 10 años mediante la copia de 9 figuras geométricas. Se basa en la teoría de la Gestalt y puede detectar problemas en el aprendizaje o desarrollo. Consiste en 30 ítems que miden errores como distorsión de formas, perseverancia e integración. Una puntuación alta indica un bajo rendimiento en percepción visomotriz.
Ecstasy, also known as MDMA, is a synthetic psychoactive drug that alters mood and perception. It was first patented in 1913 but later banned in 1985 due to its negative health effects. While it produces feelings of euphoria and intimacy, it can also cause physical issues like increased heart rate and psychological problems such as depression and anxiety. Long-term use has been linked to brain damage and other serious health problems. Ecstasy remains illegal but is still used recreationally, especially at clubs and music events.
The document provides information on MDMA (Ecstasy/Molly) including its discovery, history of use, effects, and legal status. It was first synthesized in 1912 as a substance to stop abnormal bleeding but research was suspended. In the 1970s, chemist Alexander Shulgin rediscovered its psychoactive effects and published reports of its use. Psychotherapists began experimenting with MDMA to help patients, believing it created "primordial innocence". Throughout the 1980s, MDMA spread widely and was produced on a large scale before being made illegal and classified as a Schedule 1 drug in 1985 due to its abuse potential and lack of accepted medical use.
Ecstasy is a dangerous drug that can have serious short-term and long-term health effects. While it is often portrayed as a "love drug" that enhances sensations, in reality it contains hallucinogenic substances that can cause scary experiences and psychological problems. The document discusses the physical health risks of taking Ecstasy such as dehydration, exhaustion, liver and kidney damage, and even death. It also notes the potential for psychological addiction and that users often move on to other harder drugs to cope with the negative effects. Overall, the document aims to provide facts about Ecstasy and discourage its use by highlighting the very real health dangers.
The document provides an overview of the four main classes of hallucinogenic drugs: serotonergic hallucinogens like LSD and psilocybin; methylated amphetamines like MDMA; anticholinergic hallucinogens found in plants; and dissociative anesthetics like PCP. It discusses the history of hallucinogen use from the 1960s counterculture movement to current trends, physiological and psychological effects of different classes of drugs, risks and adverse effects, and mechanisms of action in the brain.
Psychedlics & applications in PTSD treatment Hayley Peerless
This document summarizes research on the potential applications of psychedelic drugs like MDMA and psilocybin in treating anxiety disorders such as PTSD. It discusses studies that found psychedelic-assisted psychotherapy using these drugs showed promise in reducing symptoms of PTSD and depression in participants. For example, a study on MDMA-assisted therapy found one participant, Nicholas Blackston, had a realization about self-healing during a session. The document also reviews research on the mechanisms of action, risks, and legal status of psychedelics. It calls for further research with larger and more diverse cohorts and different treatment timelines.
MDMA, also known as ecstasy, can induce feelings of intimacy and reduce anxiety. While it has potential therapeutic benefits, it also has dangerous side effects. A study found that MDMA-assisted psychotherapy significantly reduced symptoms of PTSD in patients who had not benefited from other treatments. However, MDMA use carries risks of overdose and long-term neurotoxicity. More research is still needed to fully understand the risks and potential medical applications of MDMA.
MDMA (ecstasy) can induce euphoria and reduce anxiety and depression. It is being studied for potential therapeutic uses for PTSD and cancer patients. While it can provide benefits, it also has risks. Short term side effects include increased heart rate, sweating, and jaw clenching. Long term risks include depression, anxiety, and memory loss. A clinical trial found MDMA-assisted psychotherapy significantly improved symptoms of PTSD in patients who had not benefited from other treatments. However, more research is still needed to fully understand ecstasy's risks and potential medical applications.
The document discusses the history and therapeutic potential of using entheogens (psychedelics) in psychotherapy. It describes how LSD and psilocybin were used in the 1950s and 1960s to help uncover unconscious material and facilitate psychotherapy, but research was halted in 1964. Recent studies have re-examined entheogens' ability to occasion mystical experiences and increases in openness. The document argues entheogens may help connect people to spirituality and higher states of consciousness, suggesting their therapeutic use could benefit conditions like addiction, anxiety, and existential distress.
Transcending the Medical Frontiers Exploring the Future of Ps.docxedwardmarivel
Transcending the Medical Frontiers: Exploring the Future of Psychedelic Drug Research by David Jay B
Main Book Content:
29
Transcending the Medical Frontiers: Exploring the Future of Psychedelic Drug Research by David Jay Brown
Prepared by: Mary H. Maguire, California State University, Sacramento Article Kim Schnurbush, California State University,Sacramento
Transcending the Medical Frontiers
Exploring the Future of Psychedelic Drug Research
David Jay Brown
Learning Outcomes
After reading this article, you will be able to:
• Discuss the history of psychedelic drug use.
• Discuss the medical benefits of psychedelic drugs.
• Analyzetheargumentsforandagainstthemedicaluseof psychedelic drugs.
When I was in graduate school studying behavioral neuroscience I wanted nothing more than to be able to conduct psychedelic drug research. However, in the mid-1980s, this was impossible to do at any academic insti- tution on Earth. There wasn’t a single government on the entire planet that legally allowed clinical research with psychedelic drugs. However, this worldwide research ban started to recede in the early 1990s, and we’re currently witnessing a renaissance of medical research into psychedelic drugs.
Working with the Multidisciplinary Association for Psyche- delic Studies (MAPS) for the past four years as their guest edi- tor has been an extremely exciting and tremendously fruitful endeavor for me. It’s a great joy to see how MDMA can help people suffering from posttraumatic stress disorder (PTSD), how LSD can help advanced-stage cancer patients come to peace with the dying process, and how ibogaine can help opi- ate addicts overcome their addiction. There appears to be enor- mous potential for the development of psychedelic drugs into effective treatments for a whole range of difficult-to-treat psy- chiatric disorders.
However, as thrilled as I am by all the new clinical studies exploring the medical potential of psychedelic drugs, I still long for the day when our best minds and resources can be
applied to the study of these extraordinary substances with an eye that looks beyond their medical applications, toward their ability to enhance human potential and explore new realities.
This article explores these possibilities. But first, let’s take a look at how we got to be where we are.
A Brief History of Time-Dilation Studies
Contemporary Western psychedelic drug research began in 1897, when the German chemist Arthur Heffter first isolated mescaline, the primary psychoactive compound in the peyote cactus. In 1943 Swiss chemist Albert Hofmann discovered the hallucinogenic effects of LSD (lysergic acid diethylamide) at Sandoz Pharmaceuticals in Basel while studying ergot, a fun- gus that grows on rye. Then, 15 years later, in 1958, he was the first to isolate psilocybin and psilocin—the psychoactive components of the Mexican “magic mushroom,” Psilocybe mexicana.
Before 1972, nearly 700 studies with LSD and other psyche- delic drugs wer ...
The document provides an overview of ecstasy/MDMA, including its history, chemistry, effects, symptoms of use, trends in college student usage, and legislative efforts to address the drug. It was discovered in Germany in 1913 and studied as a potential chemical weapon before gaining popularity as a recreational drug in the 1980s. MDMA increases serotonin, dopamine, and norepinephrine levels and can cause euphoria but also neurological and physical side effects. Usage among college students rose significantly in the late 1990s according to one study. Various laws have aimed to target trafficking and hold rave organizers responsible.
Schizophrenia has been described since ancient times, with formal diagnosis beginning in the late 19th century. Eugen Bleuler coined the term "schizophrenia" in 1911 to describe fragmented thinking. Research in the mid-20th century focused on family dynamics and genetics, finding that schizophrenia has genetic risk factors. Early treatments included sleep temple therapy, insulin shock therapy, bathing therapy, and electroconvulsive therapy, but these were replaced by first-generation antipsychotic drugs in the 1950s and later by second-generation atypical antipsychotics with fewer side effects.
This document discusses the work of Thomas Szasz and other critics of modern psychiatry. It argues that the concept of "mental illness" is a myth and that behaviors labeled as mental illnesses are often normal reactions to life experiences or social problems. It raises concerns that psychiatric diagnoses are subjective and that psychotropic drugs can have dangerous side effects like increased suicide risk or contributing to acts of violence. The document questions the close relationship between psychiatry and pharmaceutical companies.
LSD and Albert Hofmann Trick Tract (Parody of 'Chick Tracts')Anton Novikov
Dr. Albert Hofmann accidentally ingested LSD while researching lysergic acid compounds at a Swiss pharmaceutical company in 1943. This led to him experiencing the first LSD trip, noticing effects like altered perception and an "inebriated dream-like state." He then intentionally ingested a small dose of LSD to study its effects, experiencing profound alterations in consciousness including fear and vivid hallucinations while cycling home. This self-experiment marked the discovery of the psychedelic effects of LSD. Later research found LSD could induce mystical or religious experiences and showed promise for treating conditions like alcoholism and cancer-related anxiety, though it was later banned for recreational use.
The disadvantage of MDMA or Ecstasy use has been reported to lead to clinical depression, confusion, panic attack ,anxiety, and sleep depravations. Other negative side effects of using Ecstasy involve:
The document discusses developing novel molecular descriptors for antimicrobial peptides (AMPs) using machine learning methods. It aims to use distances between transmembrane proteins of different organisms as descriptors in quantitative structure-activity relationship (QSAR) models to improve selectivity predictions of AMPs. A workflow is proposed that involves selecting homogeneous AMP datasets, developing QSAR models using genetic algorithms and artificial neural networks, defining new distance-based metrics between proteomes, and testing the novel molecular descriptors.
This document is a thesis submitted by Federica Campana for a PhD in molecular dynamics investigations of drug-cell membrane interactions. It summarizes research on how drug molecules interact with and influence cell membranes. Key findings include that membrane cholesterol content influences the effects of membrane fluidizers and heat shock protein co-inducers. Hydroxylamine derivatives were found to modify membrane physical state and induce heat shock proteins. Hydroxy arachidonic acid was identified as a potential new non-steroidal anti-inflammatory drug that targets cyclooxygenase enzymes with less affinity than arachidonic acid.
This document summarizes Federica Campana's doctoral thesis on investigating drug-cell membrane interactions using molecular dynamics simulations. The thesis examines how membrane composition influences the effects of membrane fluidizers and heat shock protein co-inducers. It also analyzes the binding of anti-inflammatory molecules like hydroxyarachidonic acid to cyclooxygenase enzymes. The overall goal is to better understand how drug molecules interact with and modulate lipid bilayer properties at a molecular level.
The document summarizes 4 projects being conducted as part of a PhD program:
1) Studying the effect of G protein lipids on membrane structure using molecular dynamics simulations. Results show the lipids interact differently with the membrane.
2) Examining 2-hydroxy arachidonic acid as a potential anti-inflammatory drug through binding energy and docking analyses with COX enzymes. It may have advantages over arachidonic acid.
3) Investigating how the drug BGP-15 remodels plasma membrane rafts using density profiles. It enhances docking with cholesterol-rich regions and increases order.
4) Developing GRIMD, a system for distributed molecular dynamics simulations across multiple machines
Sanatan Vastu | Experience Great Living | Vastu ExpertSanatan Vastu
Santan Vastu Provides Vedic astrology courses & Vastu remedies, If you are searching Vastu for home, Vastu for kitchen, Vastu for house, Vastu for Office & Factory. Best Vastu in Bahadurgarh. Best Vastu in Delhi NCR
The Hope of Salvation - Jude 1:24-25 - MessageCole Hartman
Jude gives us hope at the end of a dark letter. In a dark world like today, we need the light of Christ to shine brighter and brighter. Jude shows us where to fix our focus so we can be filled with God's goodness and glory. Join us to explore this incredible passage.
The Enchantment and Shadows_ Unveiling the Mysteries of Magic and Black Magic...Phoenix O
This manual will guide you through basic skills and tasks to help you get started with various aspects of Magic. Each section is designed to be easy to follow, with step-by-step instructions.
The Book of Samuel is a book in the Hebrew Bible, found as two books in the Old Testament. The book is part of the Deuteronomistic history, a series of books that constitute a theological history of the Israelites and that aim to explain God's law for Israel under the guidance of the prophets.
Heartfulness Magazine - June 2024 (Volume 9, Issue 6)heartfulness
Dear readers,
This month we continue with more inspiring talks from the Global Spirituality Mahotsav that was held from March 14 to 17, 2024, at Kanha Shanti Vanam.
We hear from Daaji on lifestyle and yoga in honor of International Day of Yoga, June 21, 2024. We also hear from Professor Bhavani Rao, Dean at Amrita Vishwa Vidyapeetham University, on spirituality in action, the Venerable BhikkuSanghasena on how to be an ambassador for compassion, Dr. Tony Nader on the Maharishi Effect, Swami Mukundananda on the crossroads of modernization, Tejinder Kaur Basra on the purpose of work, the Venerable GesheDorjiDamdul on the psychology of peace, the Rt. Hon. Patricia Scotland, KC, Secretary-General of the Commonwealth, on how we are all related, and world-renowned violinist KumareshRajagopalan on the uplifting mysteries of music.
Dr. Prasad Veluthanar shares an Ayurvedic perspective on treating autism, Dr. IchakAdizes helps us navigate disagreements at work, Sravan Banda celebrates World Environment Day by sharing some tips on land restoration, and Sara Bubber tells our children another inspiring story and challenges them with some fun facts and riddles.
Happy reading,
The editors
Protector & Destroyer: Agni Dev (The Hindu God of Fire)Exotic India
So let us turn the pages of ancient Indian literature and get to know more about Agni, the mighty purifier of all things, worshipped in Indian culture as a God since the Vedic time.
The forces involved in this witchcraft spell will re-establish the loving bond between you and help to build a strong, loving relationship from which to start anew. Despite any previous hardships or problems, the spell work will re-establish the strong bonds of friendship and love upon which the marriage and relationship originated. Have faith, these stop divorce and stop separation spells are extremely powerful and will reconnect you and your partner in a strong and harmonious relationship.
My ritual will not only stop separation and divorce, but rebuild a strong bond between you and your partner that is based on truth, honesty, and unconditional love. For an even stronger effect, you may want to consider using the Eternal Love Bond spell to ensure your relationship and love will last through all tests of time. If you have not yet determined if your partner is considering separation or divorce, but are aware of rifts in the relationship, try the Love Spells to remove problems in a relationship or marriage. Keep in mind that all my love spells are 100% customized and that you'll only need 1 spell to address all problems/wishes.
Save your marriage from divorce & make your relationship stronger using anti divorce spells to make him or her fall back in love with you. End your marriage if you are no longer in love with your husband or wife. Permanently end your marriage using divorce spells that work fast. Protect your marriage from divorce using love spells to boost commitment, love & bind your hearts together for a stronger marriage that will last. Get your ex lover who has remarried using divorce spells to break up a couple & make your ex lost lover come back to you permanently.
Visit https://www.profbalaj.com/love-spells-loves-spells-that-work/
Call/WhatsApp +27836633417 for more info.
The Book of Ruth is included in the third division, or the Writings, of the Hebrew Bible. In most Christian canons it is treated as one of the historical books and placed between Judges and 1 Samuel.
Trusting God's Providence | Verse: Romans 8: 28-31JL de Belen
Trusting God's Providence.
Providence - God’s active preservation and care over His creation. God is both the Creator and the Sustainer of all things Heb. 1:2-3; Col. 1:17
-God keep His promises.
-God’s general providence is toward all creation
- All things were made through Him
God’s special providence is toward His children.
We may suffer now, but joy can and will come
God can see what we cannot see
A375 Example Taste the taste of the Lord, the taste of the Lord The taste of...franktsao4
It seems that current missionary work requires spending a lot of money, preparing a lot of materials, and traveling to far away places, so that it feels like missionary work. But what was the result they brought back? It's just a lot of photos of activities, fun eating, drinking and some playing games. And then we have to do the same thing next year, never ending. The church once mentioned that a certain missionary would go to the field where she used to work before the end of his life. It seemed that if she had not gone, no one would be willing to go. The reason why these missionary work is so difficult is that no one obeys God’s words, and the Bible is not the main content during missionary work, because in the eyes of those who do not obey God’s words, the Bible is just words and cannot be connected with life, so Reading out God's words is boring because it doesn't have any life experience, so it cannot be connected with human life. I will give a few examples in the hope that this situation can be changed. A375
A Free eBook ~ Valuable LIFE Lessons to Learn ( 5 Sets of Presentations)...OH TEIK BIN
A free eBook comprising 5 sets of PowerPoint presentations of meaningful stories /Inspirational pieces that teach important Dhamma/Life lessons. For reflection and practice to develop the mind to grow in love, compassion and wisdom. The texts are in English and Chinese.
My other free eBooks can be obtained from the following Links:
https://www.slideshare.net/ohteikbin/presentations
https://www.slideshare.net/ohteikbin/documents
3. Fast forward to Christmas Eve of 1912,
when a new savior is born…
The German pharmaceutical company Merck files a procedure patent that mentions
3,4-methylenedioxymethamphetamine (MDMA) and 3,4-methylenedioxyamphetamine (MDA)
as intermediate chemicals used in a novel synthesis of clotting agents.
4. While investigating drugs
for use in chemical warfare in 1953,
the United States Army studies MDMA,
MDA, and other psychedelics in animals.
That same year an Army-contracted physician
experimentally injects a psych patient with a
fatal overdose of 500 milligrams of MDA.
5. In 1959, UCLA psychopharmacologist Gorden Alles reports on the effects of orally consumed MDA.
After taking a total of 126 mg, he describes hallucinating diaphanous smoke rings in the air.
6. While working for Dow Chemical, Alexander
“Sasha” Shulgin investigates psychedelics.
He first synthesizes MDMA in 1965, but he
doesn’t try it himself until some years later.
He finds it offers him an undistorted “window”
into his inner and outer realms. His friends try it
and have similarly positive results.
7. One such friend, the elderly psychologist
Leo Zeff, tries some of Shulgin’s MDMA in 1977.*
He immediately dismisses his plans for a quiet retirement
and spends the next decade turning on hundreds of other
therapists. Zeff calls the drug “Adam,” as he feels that it strips
away ego defense mechanisms, returning the user
to a primordial state of innocence.
*That same year Shulgin tries a psychoactive dose of his own chemical spin-off of MDMA,
3,4-methylenedioxy-N-ethylamphetamine (MDE), which later becomes known as “Eve” in the underground.
8. In 1981 researchers Myron and Jean Stolaroff interview Zeff, recording his techniques.
“A single MDMA-assisted
therapy session could accomplish
as much as six or more months of
traditional therapy.”
Therapists find MDMA to be of immeasurable value for trauma and grief counseling,
for improving relationships, and for those facing terminal illness.
9. Some experts feel that the term “psychedelic” doesn’t accurately describe MDMA’s effects…
“You feel EMPATHY
for others!” “No, you feel in TOUCH
with yourself!”
“What about
ENTHEOGEN?
Um… guys?”
…Ralph Metzner proposes “empathogen” in 1983. David Nichols suggests “entactogen” in 1986.
10. And indeed, MDMA’s effects can be profoundly spiritual. A Benedictine monk describes MDMA as
“opening a direct link with God.” A rabbi recalls his “great delight of loving the universe and feeling
loved by the universe.” A Buddhist monk expresses that MDMA helped him to become enlightened.
And the Indian guru Bhagwan Shree Rajneesh’s followers start to distribute the drug internationally.
11. Catholic priest Michael Clegg had spent his whole life wanting to know the thoughts of God…
…and MDMA completely fulfills this desire for him.
“It’s like Moses on the mountain,
with the revelation!”
Clegg christens MDMA with the name “Ecstasy,” and begins his mission to get it to the whole world.
12. MDMA’s popularity increases. While 10,000 doses are estimated to have been consumed across
America in 1976, by the mid-1980s Clegg is flooding the city of Dallas with nearly 500,000 doses
per month.* Pills can be purchased at nightclubs using a credit card, making Clegg a millionaire.
*ABC News. Other sources have estimated 30,000 pills per month.
13. The San Francisco Chronicle reports on
“The Yuppie Psychedelic” in June of 1984.
On July 27 of that same year the DEA
announces its intention to make MDMA illegal.
By August, the DEA has received letters
requesting a hearing from professor
Thomas Roberts, chemist Dave Nichols,
psychiatrist George Greer, and many others.
14. On April 25, 1985, the Donahue Show points out the benefits of MDMA therapy,
while acknowledging the increase in recreational use.
“It makes you love everybody!
Now who doesn’t want to take Ecstasy?!”
The DEA quickly institutes an “emergency” one-year ban on MDMA.
15. MDMA’s legal status ping-pongs over the next
few years. The DEA ignores their Judge
Francis Young’s hearing recommendation,
and MDMA is ultimately placed into Schedule I.
“It should be in Schedule III.”
In 1986 Rick Doblin founds the Multidisciplinary
Association for Psychedelic Studies (MAPS) to
fund MDMA research. An unrelated Swiss psycho-
therapy study occurs between 1988 and 1993,
but getting U.S. research approved is difficult.
16. Illicit recreational use, on the other hand,
explodes in the late 1980s and early 1990s,
due to a cultural phenomenon called “raving.”
Drug-inspired trance dancing becomes
the spiritual practice of youth worldwide.
E
for ec
by Nich
stasy
olas Sa
unders
New books about psychedelics,
including several monographs on MDMA,
target a growing interest.
17. One bright research note is the 1992 FDA
“Ecstasy burns holes into your brain!”
approval of Dr. Charles S. Grob’s investigation
into human psychobiologic effects of MDMA.
Harbor-UCLA
Medical Center
But anti-drug propaganda still rules the roost,
promoting unreasonable fears of neurotoxicity.
Even Oprah Winfrey acts as a government shill.
19. Since 1989, the National Institute on Drug Abuse
has been funding George Ricaurte’s research team
to the tune of over 15 million dollars, gunning for him
to show negative effects from MDMA. Appreciating
where his grant money is coming from, Ricaurte’s
2002 paper in Science states that MDMA causes
severe dopamine neurotoxicity and death in primates
following the administration of a single “recreational”
dose. However, Ricaurte submits a full retraction
a year later, when it is discovered that
methamphetamine had been accidentally (?)
administered to research animals instead of MDMA.
“Oops.”
20. Mainstream news media has a field day; dozens of articles point out Ricaurte’s mistake.
Ecstasy Rising, an even-handed TV show hosted by ABC’s Peter Jennings on April 1, 2004,
describes several U.S. government lies and the problems inherent in crying wolf.
“The government’s dramatic claims about brain
damage are exaggerated and unconvincing.”
21. In the last few years, MAPS’ research into treating
post-traumatic stress disorder with MDMA has
shown a great deal of promise. MDMA may also
be effective in treating symptoms of Parkinson’s
disease, the pain and anxiety resulting from
end-stage cancer, or the social anxiety
caused by Asperger syndrome.
22. And so, we end on a hopeful note…
“Our godfather, who synthesized heaven, Sasha be thy name…”
…in June of 2007, as we celebrate the 82nd birthday of MDMA’s godfather,
Dr. Alexander Shulgin, and raise a glass to toast his “low-calorie martini.”
23. COULD THERE BE MANY CHEMICAL PATHS TO HEAVEN?
NOTHING ELSE CAN SAVE YOU. Were Entheogenic Drugs
TRUST ENTHEOGENS TODAY! the Origin of ALL Religions?
Numerous psychoactive plants and chemicals In the words of R. Gordon Wasson:
can provide valuable insights into a deeper,
all-encompassing spiritual reality. “[At] that point Religion was born, Religion pure
As Dr. Albert Hofmann himself has said: and simple, free of Theology, free of Dogmatics,
expressing itself in awe and reverence and in
“This is the reality which all of the great mystics and lowered voices, mostly at night, when people would
founders of religions described; it is in truth the gather together to consume the Sacred Element.
kingdom of heaven destined for humankind. There The first entheogenic experience could have been the
is, however, a fundamental distinction; whether one first, and an authentic, perhaps the only authentic
knows of this reality only from the reports of others, miracle. This was the beginning of the Age of the
or whether one has experienced it personally in Entheogens, long, long ago.” Wasson 1986: 78
beatific moments; spontaneously or with the aid of
entheogenic drugs.” Ott 1993: 12 To help your growth in spiritual awareness,
take The Next Step! Try an entheogen.
24. 002
Compliments of:
TRICK
PUBLICATIONS
For more information about how psychoactive drugs
MDMA
are responsible for the origins of all religion,
use an Internet search engine
and type in “entheogen.”
Looking for MDMA?
Contact a dealer in your area.
CAUTION: Following the true religion
may result in persecution and/ or
criminal penalties.