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INDIAN DENTAL ACADEMY
Leader in continuing dental education
www.indiandentalacademy.com
www.indiandentalacademy.com
 Mesenchymal
 Epithelial
 Mixed
www.indiandentalacademy.com
Incidence
 20% of all cancers in India
 Tongue and floor of mouth ca in western countries
 Buccal mucosa and alveolus in India(Gingivo buccal
cancers or Indian oral cancer
www.indiandentalacademy.com
Anatomical subsites
 Lip
 Buccal mucosa
 Alveolus
 Retro molar trigone
 Tongue
www.indiandentalacademy.com
Aetiology
 Tobacco
 Alcohol
 Viruses
 Trauma
www.indiandentalacademy.com
Spread of malignancy
 Local infiltration
 Lymphatic
 Blood borne
www.indiandentalacademy.com
Precancer
 Premalignant lesion
 Premalignant condition
Treatment by medical or surgical methods
 Leukoplakia – stripping or excision
 OSMF – Local injections, surgical release
www.indiandentalacademy.com
Clinical features of oral ca.
 Most commonly present as non healing ulcers
 Exophytic growth
 Submucosal growth with induration
 Trismus
 Restricted mobility of tongue
 Pain
 Bleeding
 Dysphagia
 Neck swelling
 Mobility of teeth
www.indiandentalacademy.com
Investigations
IMAGING
 Radiographs
 CT
 MRI
 SPECT – Single photon emission computed
tomography
 PET – positron emission tomography
 Bone scan
www.indiandentalacademy.com
 Biopsy
 FNAC
www.indiandentalacademy.com
Staging
T- Tumour size
 Tx – primary cannot be assessed
 T0 – No primary
 Tis – Ca in situ
 T1 – 2cm or less
 T2 - >2 but <4
 T3 - >4 cm
 T4 – 4A – Invading bone and adjacent muscles
 4B – To skull base, pterygoid plates, ICA
www.indiandentalacademy.com
N- Lymph node metastasis
 Nx- Regionaql lymph nodes cannot be assessed
 N0 – no nodes
 N1 – single ipsilateral <3cm
 N2 A – single ipsilateral >3 but <6 cm
 N2B – Multiple ipsilateral < 6 cm
 N2C – Bilateral or contralateral < 6 cm
 N3 - >6cm
www.indiandentalacademy.com
M- Distant metastasis
 Mx – cannot be assessed
 M0 – No distant metastasis
 M1 – metastasis present
www.indiandentalacademy.com
Staging
 Stage I – T1 N0M0
 Stage II – T2N0M0
 Stage III – T3N0M0, T1,T2,N1
 Stage IVA– T4N0M0, Any T,N2
IV B – Any T, N3
IV C – Any T, any N, M1
www.indiandentalacademy.com
Management
Depends on stage of presentation
 Surgery
 Radiotherapy
 Chemotherapy
 Combination
www.indiandentalacademy.com
Surgery
 Extent depends on the stage of presentation.
 Minimum 2 cm margin
Composite resection, Commando operation, En bloc
removal
www.indiandentalacademy.com
Neck dissection
www.indiandentalacademy.com
Radical neck dissection
Modified Radical neck dissection
Spinal accessory
Internal jugular vein
Sternocleidomastoid
(Functional neck dissection)
Selective neck dissection
Extended neck dissection
www.indiandentalacademy.com
 Radiotherapy – curative or palliative
 56- 7- gray/30 fractions/6wks
 Chemotherapy
Generally palliative
www.indiandentalacademy.com
Thank you
For more details please visit
www.indiandentalacademy.com
www.indiandentalacademy.com

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Malignant diseases of oral cavity (1) /certified fixed orthodontic courses by Indian dental academy

  • 1. INDIAN DENTAL ACADEMY Leader in continuing dental education www.indiandentalacademy.com www.indiandentalacademy.com
  • 2.  Mesenchymal  Epithelial  Mixed www.indiandentalacademy.com
  • 3. Incidence  20% of all cancers in India  Tongue and floor of mouth ca in western countries  Buccal mucosa and alveolus in India(Gingivo buccal cancers or Indian oral cancer www.indiandentalacademy.com
  • 4. Anatomical subsites  Lip  Buccal mucosa  Alveolus  Retro molar trigone  Tongue www.indiandentalacademy.com
  • 5. Aetiology  Tobacco  Alcohol  Viruses  Trauma www.indiandentalacademy.com
  • 6. Spread of malignancy  Local infiltration  Lymphatic  Blood borne www.indiandentalacademy.com
  • 7. Precancer  Premalignant lesion  Premalignant condition Treatment by medical or surgical methods  Leukoplakia – stripping or excision  OSMF – Local injections, surgical release www.indiandentalacademy.com
  • 8. Clinical features of oral ca.  Most commonly present as non healing ulcers  Exophytic growth  Submucosal growth with induration  Trismus  Restricted mobility of tongue  Pain  Bleeding  Dysphagia  Neck swelling  Mobility of teeth www.indiandentalacademy.com
  • 9. Investigations IMAGING  Radiographs  CT  MRI  SPECT – Single photon emission computed tomography  PET – positron emission tomography  Bone scan www.indiandentalacademy.com
  • 11. Staging T- Tumour size  Tx – primary cannot be assessed  T0 – No primary  Tis – Ca in situ  T1 – 2cm or less  T2 - >2 but <4  T3 - >4 cm  T4 – 4A – Invading bone and adjacent muscles  4B – To skull base, pterygoid plates, ICA www.indiandentalacademy.com
  • 12. N- Lymph node metastasis  Nx- Regionaql lymph nodes cannot be assessed  N0 – no nodes  N1 – single ipsilateral <3cm  N2 A – single ipsilateral >3 but <6 cm  N2B – Multiple ipsilateral < 6 cm  N2C – Bilateral or contralateral < 6 cm  N3 - >6cm www.indiandentalacademy.com
  • 13. M- Distant metastasis  Mx – cannot be assessed  M0 – No distant metastasis  M1 – metastasis present www.indiandentalacademy.com
  • 14. Staging  Stage I – T1 N0M0  Stage II – T2N0M0  Stage III – T3N0M0, T1,T2,N1  Stage IVA– T4N0M0, Any T,N2 IV B – Any T, N3 IV C – Any T, any N, M1 www.indiandentalacademy.com
  • 15. Management Depends on stage of presentation  Surgery  Radiotherapy  Chemotherapy  Combination www.indiandentalacademy.com
  • 16. Surgery  Extent depends on the stage of presentation.  Minimum 2 cm margin Composite resection, Commando operation, En bloc removal www.indiandentalacademy.com
  • 18. Radical neck dissection Modified Radical neck dissection Spinal accessory Internal jugular vein Sternocleidomastoid (Functional neck dissection) Selective neck dissection Extended neck dissection www.indiandentalacademy.com
  • 19.  Radiotherapy – curative or palliative  56- 7- gray/30 fractions/6wks  Chemotherapy Generally palliative www.indiandentalacademy.com
  • 20. Thank you For more details please visit www.indiandentalacademy.com www.indiandentalacademy.com