Major connectors unite the major parts of the denture framework and provide cross-arch stability. Minor connectors connect the major connector to other framework components to transfer stresses. Rests and rest seats provide vertical support on tooth surfaces. Direct retainers resist movement away from teeth, while indirect retainers provide retention for distal extension bases when dislodged from their seats. Key considerations in design include rigidity, contour, avoidance of impingement, and ensuring proper cleansing access.