SlideShare a Scribd company logo
Linkatu: Linked data in
industry
W3C, Granada 2012
http://richard.cyganiak.de/2007/10/lod/
“the value of your information
grows exponentially with your
ability to combine it with new
information”
– Henry Story, Sun Microsystems
BBC and Linked Data
       @metade
http://www.bbc.co.uk/programmes/b00hqlc4
http://www.bbc.co.uk/music/artists/70248960-cb53-4ea4-943a-edb18f7d336f
http://en.wikipedia.org/wiki/Springsteen
http://musicbrainz.org/artist/70248960-cb53-4ea4-943a-edb18f7d336f
http://www.bbc.co.uk/nature/life/Lion
http://en.wikipedia.org/wiki/Lion




                         http://dbpedia.org/page/Lion
http://www.w3.org/2001/sw/sweo/public/UseCases/Volkswagen/
Domain Driven Design
Website is the API
  Persistence
  Linked Data
  RESTful
Internet is the CMS
opendata
Officially launched 21st January 2010
http://www.legislation.gov.uk/
data.worldbank.org
http://openelectiondata.org/
http://data.nytimes.com/
http://datos.fundacionctic.org/sandbox/catalog/faceted/
http://www.guardian.co.uk/news/datablog
http://www.guardian.co.uk/news/datablog
opendata
Open about what you do
Open about what you know
Open to new engagement
Supporting others to be open
Semantic Web projects in
 life sciences and health
    care environments
         @Linkatu
Drug Development Process
                                   Early Clinical
         Discovery                                        Development
                                       Dev.

    TI              HI        LO      ECD      PoC      DfL        Reg    LCM



    Preclinical studies                         Clinical studies
 • Target Identification                      • Proof of Concept
 • Hit Identification                         • Development for Launch
 • Lead Optimisation                          • Registration and Launch
                                              • Life Cycle Management

The way to semantic Service
Oriented Architecture
$1,000 genome;
 $100,000 analysis?
50 million sequences
obtained by 2015
 The pharma industry loses
 $4.2 billion per year due to
 drug trial delays
http://www.flickr.com/photos/nic221/391536867/
1.5M publications/year


1 15
  million       million
  authors       readers
                at >10,000
                institutions




 1.5B       downloads
            per year
20billion€
too much to read

  too expensive

too difficult to find
http://linkedlifedata.com/
code.google.com/p/bio2rdf
what is a “data market place" ?




     Service that make it easy to find data from a
     range of secondary data sources, then consume
     the data in a usable and unified format. Several
     of these services are trying to create
     marketplaces for data, envisioning that data
     providers can offer their data sets for sale to
     data seekers
what is a "platform" ?



          a place where we
          encourage...
          support...
          enable...
          our communities
You own the data
You control access
You can pull it/change it
You can delete it
You can decide what is best
Translational Medicine Platform for Alzheimer´s Disease
Data Integration Platform for Patients, Physicians and Researchers
Use Tabs for play each role.
http://85.48.202.13:8080/AD/index.html
Being a Patient
Monitor your progress
Know Side Effects of Drugs you are taking
Mappings to Generic Ontologies
ICD9 Coded
Being a Physician
Monitor your patients
Retrieve info from PubMed
Answer complex queries
Are there active clinical trials that my patients may   participate with different MOA
because of side effects?
Being a Researcher
Retrieve information from distributed sources
Get the latest relevant scientific articles
Answer complex queries
What Biomarkers are associated with or implicated in Alzheimer´s Disease?
Breast Cancer Decision Support System
http://85.48.202.13:8080/BreastCancer/BC.html
Deployed at Cruces Hospital – Bilbao
Use of Description Logic and Inference Rules to deduce the Diagnosis and Treatment
Customized Breast Cancer ontology
Information Retrieval from Distributed Sources for Breast Cancer
Matchmaking process between Patient´s PHR and Distributed Sources
Retrieves Information such as Clinical Trials, PubMed articles, Adjuvant Treatments, genes,…
Information Retrieval from Distributed Sources for Breast Cancer
Matchmaking process between Patient´s PHR and Distributed Sources
Retrieves Information such as Clinical Trials, PubMed articles, Adjuvant Treatments, genes,…
OmicsHub
http://85.48.202.13:8080/SWDemo/index.jsp




The inputs for the prototype will be a list of genes and a list of proteins which have
been acquired from different time points of the lifecycle of a cell.
Integrate Both Datasets
Find Relevant Pubmed Articles
Organize into clusters
Known Protein Interactions
The data marketing ecosystem—beyond APIs.



 Marketers        Marketers         Developers




                                      Data
Consumers        Consumers
                                   Applications
                                     Copyright © 2010 Scott Brinker




 Marketing               Data Marketing
Mendeley Snags $2 Million In Early-Stage
Funding For Research Paper Management Tool

        "Data marketplace" Infochimps raises
        $1.2M to build out its data offerings

Factual, a startup that claims to host hundreds
of thousands of data sets, has raised $25
million in its first round of institutional funding.

    Sermo Closes 26.7 Million in Funding to
    Evolve Online Community for Physicians
 PatientsLikeMe take in $8M funding
hola@linkatu.net

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