Kaleido Webinar: Transforming Healthcare with Blockchain

1. WEBINAR
Digitally Transforming
Healthcare with Blockchain

2. Jamie Kurtz Lana KalashnykHeather FlannerySophia Lopez
Founder & COO,
Kaleido
Founder & CEO,
ConsenSys Health
Blockchain Partner
Technology Lead, PSA,
AWS
CTO
Diagnotes
Meet the Speakers

3. 1 Current Healthcare Trends (Heather Flannery)
2
3
4
5
Blockchain in Healthcare (Heather Flannery and
Sophia Lopez)
Private Data Marketplace Demo (Sophia Lopez)
AWS Solutions for Healthcare (Lana Kalashnyk)
Diagnotes Collaboration Platform (Jamie Kurtz)
Agenda

4. Technology platform for
digitally transforming
modern business networks
Leveraging blockchain
and machine learning for
sustainable and value-
based healthcare
Leading cloud provider
with best-in-class services
for your decentralized
Apps
Partnering to accelerate the digital
transformation of healthcare solutions
+ +

5. Current
trends in
healthcare

6. The cost of
administrative
waste in healthcare
exceeds $200B
annually in the US
Healthcare is
ready for digital
transformation
*https://www.modernhealthcare.com/opinion-editorial/reduce-total-cost-care-6-reasons-why-providers-and-payers-should-tackle-challenge

7. Blockchain
in
healthcare

8. The PHI Readiness Framework
In developed health economies, the barrier of regulatory risk and uncertainty creates opportunity through
evolving views on ethical data governance
PopulationHealthImpact
Time & PHI Involvement
Non-PHI Use Cases
All forms of IRB-Overseen
Health Research
Fully-Identified,
Biometrically Attested,
Sensitive PHI Use-Cases
➔ Supply Chain
➔ Provider Directory
➔ Contracting
➔ Credentialing
➔ Aspects of Revenue Cycle
➔ “Walled Garden” Paradigm
➔ Advancing Ethical and Scientific
Values
Stage Three use-cases can be brought into
the Stage Two interval when under an IRB-
overseen research protocol.
➔ Care Coordination
Across Org Boundaries,
Clinical Integration
➔ Precision Medicine,
Personalization
➔ APMs: Value-Based Care
➔ Ultra-Secure, Incentivized
Digital Therapeutics
1 2 3

9. 05
04
03
02
01
Over 75 enterprise applications to join SHA received; new memberships suspended while governance matures.
Two additional big pharma participants soon to be announced, still confidential.
More than ten large enterprises remain confidential, to be announced.
Health Utility
Network
(“HUN,” rebranding in progress)
Announced January 2019;
prioritized use-cases still
confidential, major
announcements anticipated
Nov/Dec ‘19
Announced April 2018;
initial focus
shared provider data
management
Announced April 2019;
initial focus
shared accumulator
administration
Announced July 2019;
initial focus federated
learning for drug
discovery
Announced July 2018;
initial focus clinical
trials, health data
exchange, supply
chain
There are important blockchain business networks
emerging in healthcare today

10. Blockchain Networks
Public, Private, and Hybrid
Optional Tokenized Assets
Secured and Transferred
1. Old tech used in a new way
2. Creates potential for
entirely new business
models
3. Opportunity to apply game
theory and behavioral
economics at scale
4. AI for optimization of
incentives
5. New converging
innovations, “Privacy-in-
Depth” and “Decentralized
AI”
Web2 or Today’s Mainstream Modern Web
Smart Contracts
Secure Automation Across
Organizational Boundaries
Decentralized Apps (“dApps”)
Web3 User Experience
Privacy-in-Depth
• Zero-Knowledge Proofs (ZKPs)
• Trusted Execution Environments (TEEs)
• Secure Encrypted Virtualization (SEV)
• Blind Computation
• Verifiable Computation
• Secure Multi-Party Computation
• Differential Privacy
• Homomorphic Encryption
• Quantum-Resistant Encryption
Decentralized AI
• Federated learning in blockchain networks
• Intelligent agent-based automation
• Optimization w/agent-based simulation
• New paradigm in training data provenance
A new scope for ‘blockchain’ and ‘web3’

11. Kaleido’s Blockchain Business Cloud
Business Networks Made Radically Simple For the Enterprise

12. From concept
to consortium
A steep mountain to climb
Technology Curve
Core technology
adoption
Shared IT
Distributed
ownership and
governance
Consortia Building
Scale diverse business
networksPoC
PILOT
PRODUCTION

13. Examples of clients transforming healthcare
Accelerating next-
generation TB disease
surveillance to protect
U.S. public health
ePrescriptions to bring
the right data to the
right place for the right
patient
Enabling a genomic
data exchange to
address rising diabetes
rates in China
Large
Government
Agency
Optimizing the Food
Safety Inspection
process to be more
efficient, faster and less
costly to execute
Aligning technology
with what healthcare
professionals do best…
collaborate in teams
and take care of
patients

14. Diagnotes
collaboration
platform

15. Our mission
INDUSTRY SPECIFIC
Designed by healthcare
professionals for
healthcare professionals
INTUITIVE
Easy-to-use platform
that reflects standard
smartphone
functionality
EMPOWERS TEAMS
Leverages natural
team collaboration
and communication
We deliver communication tools that reflect the natural habits of
healthcare professionals and patients.

16. The evolution
Although many technologies claim to support the communication needs of
healthcare professionals, none have done so adequately.

17. Diagnotes next generation
It’s time to move beyond secure messaging
Diagnotes is aligning technology with what healthcare professionals do
best… collaborate in teams and take care of patients.
Team-Focused Patient-Centric Workflow-Automation

18. Team rooms
Diagnotes gets everyone in the same “room”
Team Rooms mirror the natural workflows of the
healthcare professional, making Diagnotes very simple
and intuitive to use.
Clinicians can dialogue and share information via text,
voice recordings, video, or attachment.
CUSTOMIZABLE
WORKSPACES
TEAM COLLABORATION,
NOT POINT-TO-POINT
INTELLIGENT
NOTIFICATIONS
RECOGNIZES TEAM
FLUIDITY
CENTRALIZED
INFORMATION HUB

19. Patient rooms
Virtual Rooms where patient care teams can collaborate
Workspaces that are automatically created for each patient and uniquely
reflect each patient’s care needs
Positive identification and preservation of patient context
Created automatically via HL7 integration
Link the Team Rooms, mirroring active patient lists
Integrated data feeds for immediate access to key clinical
information

21. Diagnotes solution architecture

22. Private data
marketplace demo
on Kaleido

23. Typical projects have over 40 components
Modernizing business networks
The chain is
ONLY 5%
of a complete
blockchain solution

24. Full Stack blockchain for the modern business network

25. Immutable Private Data Exchange
Share public data among companies and participants with the ability to pin
private data to a blockchain and to provide real-time updates. A token
based economy helps align incentives to contribute and maintain the data
quality
● Data storage & transfer is done off-chain
● Proof (Hash) of transaction is sent to the blockchain
● Everybody has a representation of the content (no deniability)
Event
Streams
Document
Store
On Chain
Registry
Rest API
Gateway
Smart
Contracts
This solution utilizes the following Kaleido plug-and-play
services:
Kaleido
demo

26. Demo time

27. AWS
solutions for
healthcare

28. AWS Healthcare Customers

29. Trends
54%
Percentage of Hospital
CEOs who say the
transition from volume to
value is their biggest
financial challenge
Value-based care
Amount of data that will
be generated globally in
2025. 10 times the 16.1
ZB of data generated in
2016
163ZB
Increasing volume
of digital data
Rate at which computer
processing power
doubles, according to
Moore’s Law
18 months
Continuous
technology advances
1 per day
Rate of security breaches
(ransomware and hacking)
in 2016 across healthcare
organizations
Sophisticated
security breaches
Sources: 2016 American College of Healthcare Executives Annual Survey; Moore’s Law; IDC Forecast, April 2017; Breach Barometer Report: Mid-Year 2017, by
Protenus, Inc.

30. Where AWS supports healthcare providers
Storage and Archiving Core Operations and
Business Continuity
Care Coordination
Patient Engagement Clinical and Population
Health Analytics
Clinical
Information Systems

31. Solutions powered by AWS benefits
Scalable architecture to
allow rapid and dynamic
data analysis
Hyperscale storage with
automated life cycle
management and deep
analytics tools
Flexible infrastructure
to leverage ever-
advancing technology
Automated security
and compliance
checks reduce risk
AWS Benefits
Extracting valuable insights
from data becomes far more
complicated
Traditional IT model &
internal systems lack
necessary agility
Lack of resources to
implement data-driven
decision making
Patient data & compliance
standards vulnerable to
compromise
Provider Challenges
Value-based care
Increasing volume of
digital data
Continuous technology
advances
Sophisticated
security breaches
Trends

32. Provider challenges
Value-based care
Increasing volume of
digital data
Continuous technology
advances
Sophisticated
security breaches
Trends
Extracting valuable
insights from data
becomes far more
complicated
Traditional IT model &
internal systems lack
necessary agility
Lack of resources to
implement data-driven
decision making
Patient data & compliance
standards vulnerable to
compromise
Provider Challenges

33. How can Blockchain enable
Healthcare customers

34. Working backwards – Decentralized trust
Financial
institutions
Peer-to-peer payments
Mortgage
lenders
Process syndicated loans
Supply chain
Transact with suppliers
and distributors
Retail
Streamline
customer rewards
21 TRANSACTIONS WITH
DECENTRALIZED TRUST
LEDGERS WITH
CENTRALIZED TRUST

35. ConsenSys Health, Kaleido and AWSOnly about 10%of a blockchain
solution
is the blockchain network!

36. Foundational
Services
Transformation and
Connectivity
API Management
Edge Services
Core Blockchain
Platform
IoT Thing
Notification
Management
Core Blockchain Platform
AnalyticsOff Chain Storage
Security
Membership and
Identity
Consensus
Smart Contract
Ledger
Transactions and
Messaging
Certificate
manager
Compute
Network
Integrations
Blockchain platform high level architecture

37. Take the next step on
your digital
transformation journey
Get started for free at
kaleido.io
Revolutionize your care team’s
workflow + collaboration @
diagnotes.com
Get in touch at
ConsenSysHealth.com
Visit the AWS Marketplace at
https://aws.amazon.com/mar
ketplace/pp/ConsenSys-
Kaleido-Enterprise-
Blockchain-
SaaS/B07CSLDS7R