This study explored the relationship between physical activity levels, telomere length, and telomerase activity in immune cells of older adults. The researchers found that moderate physical activity was associated with longer telomere length compared to low and high activity levels. No relationship was observed between activity level and telomerase enzyme activity. Additionally, individuals with the hTERT TT genotype had greater telomerase activity than other genotypes, and the TT genotype combined with high activity was associated with even greater telomerase activity. The findings suggest moderate physical activity may benefit telomere length while higher levels may not provide the same benefits.