Lecture 19 Pseudomonas
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This document discusses Pseudomonas aeruginosa, an opportunistic pathogen that causes nosocomial infections. It is a gram-negative rod that is oxidase-positive and grows well aerobically. It infects patients with compromised immune systems or wounds. Transmission occurs in hospitals via contact with contaminated surfaces or medical equipment. Laboratory diagnosis involves culturing on blood and nutrient agar to observe characteristic colonies and positive oxidase and OF tests. Treatment is difficult as it is highly resistant to many antibiotics. The document also analyzes antibiotic resistance of Pseudomonas species isolated from hospital and community cockroaches. It was found to be resistant to many commonly used antibiotics.
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TEST BANK For Community Health Nursing A Canadian Perspective, 5th Edition by...
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Lecture 19 Pseudomonas
- 1. “” بسم ا الرحمن الرحيم Pseudomonas Prof. Khalifa Sifaw Ghenghesh
- 2. Pseudomonas aeruginosa • Oxidase-positive, Strict aerobe, Gram –ve rods • A major Cause of Nosocomial Infections. • Infection Occur in Patients with Altered Host Defences, Wounds or Burns. • In Non-Hospitalized Patients: • Vehicles of Transmission:
- 4. • LABORATORY DIAGNOSIS: – On BA • Irregular, β -hemolytic colonies • Oxidase-positive • O-F test >> Aerobic – On NA • Bluish, irregular colonies • TREATMENT – Resistant to antimicrobial agents • CONTROL
- 5. Resistance of Pseudomonas aeruginosa isolated from different clinical sources to antibiotics Antibiotic No. (%) resistant (n=235) -----------------------------------------------------Cefsulodin 61 (26) Gentamicin 102 (43) Carbenicillin 113 (48)
- 6. Resistance of Pseudomonas spp isolated from hospital and community cockroaches to antibiotics No. (%) resistant Antibiotic Hospital Community Total (n=34) (n=9) (n=43) --------------------------------------------------------------------------------Ampicillin 33 (97) 9 (100) 42 (97) Amoxicillin33 (97) 9 (100) 43 (100) clavulanic acid Ceftazidime 0 (0.0) 0 (0.0) 0 (0.0) Cephalothin 34 (100) 9 (100) 43 (100) Chloramphenicol 33 (97) 9 (100) 42 (97) Gentamicin 4 (12) 0 (0.0) 4 (9.5) Nalidixic acid 34 (100) 9 (100) 43 (100) Nitrofurantoin 34 (100) 9 (100) 43 (100) Ciprofloxacin 0 (0.0) 0 (0.0) 0 (0.0) Tetracycline 32 (94) 9 (100) 41 (95.3) Trimethoprim34 (100) 9 (100 43 (100) sulphamethoxazole
- 7. Resistance of Pseudomonas spp isolated from hospital and community cockroaches to antibiotics No. (%) resistant Antibiotic Hospital Community Total (n=34) (n=9) (n=43) --------------------------------------------------------------------------------Ampicillin 33 (97) 9 (100) 42 (97) Amoxicillin33 (97) 9 (100) 43 (100) clavulanic acid Ceftazidime 0 (0.0) 0 (0.0) 0 (0.0) Cephalothin 34 (100) 9 (100) 43 (100) Chloramphenicol 33 (97) 9 (100) 42 (97) Gentamicin 4 (12) 0 (0.0) 4 (9.5) Nalidixic acid 34 (100) 9 (100) 43 (100) Nitrofurantoin 34 (100) 9 (100) 43 (100) Ciprofloxacin 0 (0.0) 0 (0.0) 0 (0.0) Tetracycline 32 (94) 9 (100) 41 (95.3) Trimethoprim34 (100) 9 (100 43 (100) sulphamethoxazole