Bring cost-effective medical instrument sterilization to district hospitals in Nepal. At the MIT Global Challenge at: http://globalchallenge.mit.edu/teams/view/213

1. Problem
“One
in
three
pa+ents
having
surgery
in
some
se3ngs
with
limited
resources
become
infected.”
-­‐
World
Health
Organiza8on
• Many
district-­‐level
hospitals
and
private
clinics
(medium
size
facili8es)
in
Nepal
use
disinfec)on
measures,
like
flaming
or
concentrated
“barbicide,”
which
kill
some
but
not
all
microbes
on
their
medical
instruments.
• Steriliza)on
via
an
autoclave
kills
all
microbes
making
tools
safe
for
surgical
use,
but
is
not
commonly
prac8ced
due
to
a
lack
of
resources
and
training.
• Improper
steriliza8on
has
been
iden8fied
as
a
key
contributor
to
a
much
greater
incidence
of
infec8on
in
developing
vs.
developed
na8ons1,2,3

2. Solu8on
Provide
Simple
and
Effec8ve
Steriliza8on
at
Low-­‐Cost
Our
product…
• Can
be
powered
by
any
locally
available
energy
source
(kerosene
in
Nepal,
coal
stoves
in
Sierra
Leone),
not
just
electricity
like
most
other
autoclaves.
• Is
small
efficient
and
portable
and
is
suitable
for
smaller
loads
of
district
level
hospitals
and
private
clinics,
unlike
the
oversized
compe88on.
• Our
product
has
an
LED
interface
which
no8fies
the
user
when
the
steriliza8on
is
complete,
while
other
autoclaves
do
not
• Our
product’s
price
range
is
much
more
appropriate
for
our
target
audience

3. Innova8on
• Low
cost
plaWorm
based
on
widely-­‐available
pressure
cookers
• Easy
for
unskilled
users
to
operate
the
straighWorward
LED
display
• Easily
to
calibrate
at
varying
eleva8ons
(very
important
at
high
eleva8on
in
Nepal)

4. Nepali
Community
Tier
2
Tier
3
• Health
posts
in
Nepal
have
8er
systems
ranging
from
1
to
4.
Our
target
audience
are
hospitals
in
8ers
2
and
3.
The
pa8ents
and
healthcare
workers
at
these
loca8ons
can
benefit
most
from
our
product.
• We
are
partnering
with
the
doctors
in
• We
will
make
mul8ple
trips
to
all
of
these
hospitals
in
the
five
loca8ons
on
the
loca8ons
in
Nepal
over
the
summer
of
right.
2011

5. 12
Month
Projec8on
Income
Q1
Q2
Q3
Q4
Revenue
$15,300
$42,500
$51,000
$51,000
COGS
$10,800
$30,000
$36,000
$36,000
Gross
Profit
$4,500
$12,500
$15,000
$15,000
Profit
Margin
42%
42%
42%
42%
Expense
Equipment
$5,080
$0
$0
$0
administra8ve
$420
$420
$420
$420
shipping
$900
$2,500
$3,000
$3,000
salaries
$480
$960
$1,080
$1,080
insurance
$0
$0
$0
$0
taxes
$1,125
$3,125
$3,750
$3,750
Total
Expense
$8,005
$7,005
$8,250
$8,250
Net
Income
($3,505)
$5,495
$6,750
$6,750
workers
2
3
3
3
units
sold
90
250
300
300

6. Team
LCAAS
(Low-­‐Cost
Advanced
Autoclave
Solu8on)
We
have
assembled
a
team
that
has
the
necessary
background
to
implement
this
undertaking
• Greg
Tao
-­‐
Team
and
Technical
Lead
• Hallie
Cho
-­‐
Business
Strategy
and
Development,
Design
consult,
Web
Designer
• Hai
Tran
-­‐
Business
Development
• Yida
Gao
-­‐
Business
Development,
Patent
Research
• Shambhu
–
Nepali
Implementa8on
Co-­‐Director
• Pramod
Krandel
–
Nepali
Implementa8on
Co-­‐Director
• Nimesh
Ghimire
–
Nepali
Organiza8onal
Support
• Dr.
Ishwar
Bhalarai
–
Medical
director
in
Nepal,
Clinical
Study
Designer
• Dr.
John
Daniel
Kelly
–
Medical
consultant

7. References
1. Allegranzi
B
et
al.
Burden
of
endemic
health-­‐care-­‐
associated
infec8on
in
developing
countries:
systema8c
review
and
meta-­‐analysis.
The
Lancet
2011;
377:
228-­‐241.
2. Eriksen
HM,
Chugulu
S,
Kondo
S,
Lingaas
E.
Surgical-­‐site
infec8ons
at
Kilimanjaro
Chris8an
Medical
Center.
J
Hosp
Infect
2003;
55:14-­‐20.
3. Fehr
J,
Hatz
C,
Soka
I,
et
al.
Risk
factors
for
surgical
site
infec8on
in
a
Tanzanian
district
hospital:
a
challenge
for
the
tradi8onal
na8onal
nosocomial
infec8ons
surveillance
system
index.
Infect
Control
Hosp
Epidemiol
2006;
27:
1401–04.
4. Centers
for
Disease
Control,
Guidelines
for
Disinfec8on
and
Steriliza8on
in
Healthcare
Facili8es
2008.